C-SHUTTLE
Glove Box
- Full Time O2/CO2 Optimization During Handling
- Full Time Protection
- Better Cell Growth
- Better Cell Health
- Maximum User Comfort
- Ample Workspace
- Accommodates Subchambers
- Hypoxia in vitro models
- Physiologic oxygen for cell culture

When you publish your data generated with this equipment, please copy and paste the below to cite it in your manuscripts.

When you publish your data generated with this equipment, please copy and paste the below to cite it in your manuscripts.
C-Shuttle Overview
CYTOCENTRIC HOOD
The C-Shuttle laboratory glove box is part of a practical system for handling your cells under the same conditions at which they incubate. It provides ample workspace where you can handle and manipulate your cells without disruption of O2 and/or CO2.
FULL TIME OPTIMIZATION DURING CELL HANDLING
Interruption in optimal O2 and/or CO2 conditions can have major effects on cell cultures. Normally when cells are manipulated outside their incubator in clean hoods, controlled gases such as CO2 and O2 are disrupted. Effects can be devastating on cultures. Consider oxygen regulated genes. Hypoxia upregulated genes are immediately shut off by even brief exposures to room air. Imagine what can happen to receptors, ion channels, cytokines, extracellular matrix, etc. when the pH changes out of the physiologic range!
DOCKS SUBCHAMBERS FROM REMOTE INCUBATORS
Using a transport vessel such as the BioSpherix C-Chamber between the C-Shuttle laboratory glove box and your incubator is the most economical way to achieve uninterrupted conditions. The incubator protects cells from exposure. The transport chamber maintains conditions for the brief period between controlled environments. The C-Shuttle hypoxia work station is controlled, and the buffer chamber allows your cells to enter without disrupting the set environment within.
PartsCOMPLETE SYSTEMThe C-Shuttle, a C-Chamber (sold separately), a gas controller (system comes with ProOx P360, other options available) and gas (customer supplied). A nitrogen gas supply is necessary for hypoxia. If CO2 control is necessary, a CO2 controller and tank of CO2 is also required. CONTROLLERSControllers such as the ProOx P360 (pictured above) and similar O2 / CO2 controllers fit the C-Shuttle. They are flexible and very capable. |
OptionsTypical configuration for one user access (Top view)Optional two user access configuration (Top view)DimensionsFront ViewBuffer End View |
Installation SchematicInstallation1. Set C-Shuttle on Secure level surface. 2. Place controller(s) on or near buffer chamber. 3. Hook up gas supply. 4. Connect the controller(s), power supply and sensor |
How It Works
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![]() Cells are moved into the buffer chamber protected inside a subchamber with opening facing the workspace. |
![]() Technician removes cells from the subchamber docked in the buffer chamber. |
![]() Cells are handled and manipulated under aseptic and optimal O2/2 conditions and returned to subchamber after handling. |
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C-Shuttles protect the researchersCells are often purposely grown and processed to generate or test viruses and vectors. More worrisome is when cells are unknowingly infected with viruses or other transmissible agents. C-Chambers will limit exposure to harmful viruses, vectors and prions where conventional open labs allow the technicians to breathe potentially dangerous non-cellular biological entities. UninterruptibilityCells removed from normal incubator and handled in normal hood are exposed to suboptimal conditions. Cells cultured in a subchamber and handled in a C-Shuttle are never exposed to suboptimal conditions. PROTECTION AGAINST CONTAMINATIONIn open labs with open hoods, cells and researchers share the critical workspace most of the time. The majority of contamination in labs is caused by humans and their bioburden. A closed environment provided by the C-Shuttle and C-Chambers ensures that the main source of contamination is removed. |