Dry Eye System

 

The Dry Eye System is engineered to deliver precision, consistency, and environmental control in in vivo research by tightly regulating conditions that significantly influence study outcomes. By enabling stable low-humidity environments and rapid transition from ambient conditions, the system improves reproducibility and data quality. Its quiet operation reduces subject stress, supporting more ethical and humane study conditions. With flexible chamber configurations, streamlined access, and retrofit compatibility, the Dry Eye System integrates easily into existing laboratory workflows, and enables researchers to generate higher-fidelity, translationally relevant data.

 

Reduce Operating Costs

Rapid and Precise RH Control

Our system enables precise control of relative humidity from 40% down to 15% (depending on ambient conditions), rapidly transitioning to target levels to minimize the time spent outside controlled environments. This tighter RH control improves data fidelity and reduces artifacts caused by environmental fluctuations.

Adaptable icon

Spacious and Adaptable Design

Multiple chamber size options (66, 30, and 15-inch) allow flexibility to fit a range of lab spaces, with the 66-inch chamber accommodating up to 14 standard rodent cages. Large doors enable fast, simultaneous access, and a retrofit kit is available to upgrade existing BioSpherix animal chambers.

Mitigate Microbial Risk

Supports Ethical in vivo Studies

Designed to support ethical, humane, and efficient in vivo studies, the system defaults to room air as a safeguard to help protect subjects. Its quiet operation further minimizes stress, helping maintain stable conditions and more reliable study outcomes.

Supporting Data

We’ve partnered with reputable Contract Research Organizations to validate in vivo studies that utilize our Dry Eye System.

1. Dry eye induction in the BioSpherix Dry Eye System resulted in an increase in corneal punctate density relative to baseline and naïve controls, indicating greater disease severity in these subjects.

2 A reduction in tear volume was observed in the dry-eye induced group relative to baseline and naïve controls.

3. Dry eye chamber maintained consistently lower, stable humidity levels compared to ambient conditions.

4. Proteomic analysis revealed several up- and down-regulated proteins corresponding to molecular changes induced by the Dry Eye System.

 

BioSpherix and Ichor Life Sciences poster presentation for ARVO, 2026

Click the poster to download