Programmed control of dynamic oxygen conditions permit a range of biological modeling possibilities. Chambers for in vitro and in vivo exposures permit highly reproducible experiments using intermittent hypoxia (IH), acute intermittent hypoxia (AIH), episodic hypoxia, and chronic intermittent hypoxia (CIH). These studies advance scientific understanding of human disease, disorders, and conditions like:
- obstructive sleep apnea (OSA)
- apnea of prematurity
- oxidative stress
- neurodegeneration (Alzheimer’s and Parkinson’s)
Therapeutic models of IH are aimed at increasing motor function following spinal cord injury (SCI) or promoting neurogenesis to offset cognitive decline.
Xvivo System Model X3
The Xvivo System Model X3 hypoxia workstation provides full-time control of hypoxia for in vitro IH studies. Configure the Xvivo System with multiple incubator chambers (up to 9) to carry out simultaneous but independent hypoxia profiles at the same time. Closed hypoxia hoods adjoin the incubator chambers permitting scientists to move cells in/out without disruption of hypoxic conditions.
OxyCycler A84XOV & A-Chamber
Optional Monitor Pod for OxyCycler A84XOV & A-Chamber monitors and records environmental conditions inside chamber: parts per million levels of carbon dioxide (CO2 ppm), relative humidity (RH), temperature, and O2 levels at any location within the chamber.
Quick & Quiet Profiler
Maximize the speed of intermittent hypoxia models with Quick & Quiet Profiler accessory kit for either OxyCycler A84XOV & A-Chamber or OxyCycler A41OV & A-Chamber. Hypoxia profiling is made more rapid while also maintaining sound levels (dB) within acceptable ranges.