NO Subchamber Cell Culture System
- First NO Gasotransmitter Cell Culture System
- Precise Automated Exposures of NO
- Dynamic or Static Exposures
- Simulate Physiologic and Pathophysiologic conditions
- Unprecedented NO Induced Phenotypes
- Keeps Unwanted NO2 Side Product Within Limits
ADVANCED GASOTRANSMITTER INCUBATION
Nitric oxide (NO) is one of the most widely studied cell gasotransmitters, but traditionally has been difficult to work with in cell culture research. Until now the only way to dose NO in cell cultures previously was with a chemical that reacted to produce or “donate” NO. Chemical NO donors are messy and crude. Exposures possible with NO donors are limited. Every attempt is difficult to control and even more difficult to reproduce. Now, with the OxyCycler GT4181N, for the first time, you can precisely and automatically control NO.
UNLIMITED PROGRAMMED, DYNAMIC EXPOSURES
Consisting of a GT41 which provides the common O2, CO2, and RH control, and the modular GT81N piggyback controller, which provides the NO, a subchamber culture system controlled by the OxyCycler GT4181N is the most advanced and reliable method for NO culture. Any dose and duration programmed, without the hassle and limitations of chemical donors. With the click of a mouse, any exposure can be precisely reproduced. In addition, an unwanted side product that forms from NO and O2 is NO2. This nuisance gas can be prevented from building up in your culture chamber by automated sensing and displacement in real time to limit the concentration of NO2. This is essential for relevant and reproducible results of NO exposures.
The controller is compatible and will fit any standard size C-Chamber. The entire system will fit any existing incubator.