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Closed incubators, hoods,
and chambers for studies of mitochondria and metabolism

Struggling to control physiologic oxygen without the right tools?
Room air oxygen adds ROS and oxidative stress to cells in culture. It can change glycolytic and oxphos metabolic programs. Most labs aren’t equipped with chambers that reproducibly control O2. This makes it difficult to accurately assess mitochondrial and metabolic function.

Get the right equipment for physiologic oxygen in vitro.

Improve Relevance and Reproducibility of Findings with Full Time Control

Options for Adding Hypoxic Control to Research

Upgrade your traditional CO2 incubator with hypoxic chambers

BioSpherix

Replace your incubator and BSC with a closed cell incubation and handling chamber

BioSpherix

How do I get cytocentric equipment FOR SIMULATING physioxia/hypoxia?

Step 2

LET US HELP YOU REFINE OR REPLACE YOUR INCUBATOR WITH CYTOCENTRIC EQUIPMENT

Step 3

Get quality results

Visit a Cytocentric Lab

Mitochondrial Research at McGill University

Metabolic Research at Tufts Medical Center

Metabolic Research at RESTORE (Toulouse)

Publications

He, Yang-Yang et al. Identification of Hypoxia Induced Metabolism Associated Genes in Pulmonary Hypertension. Front. Pharmacol 2021: 12:753727. doi: 10.3389/fphar.2021.753727

Surace, L. et al. Dichotomous metabolic networks govern human ILC2 proliferation and function. Nat Immunol. 2021; 22, 1367–1374 . doi: 10.1038/s41590-021-01043-8

Elliott RL, Jiang XP. The adverse effect of gentamicin on cell metabolism in three cultured mammary cell lines: “Are cell culture data skewed?”. PLoS One. 2019;14(4):e0214586. Published 2019 Apr 1. doi:10.1371/ journal.pone. 0214586. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443165/

Timpano S., et al., Physioxic human cell culture improves viability, metabolism, and mitochondrial morphology while reducing DNA damage. FASEB J. 2019 Apr;33(4):5716-5728. https://www.ncbi.nlm.nih.gov/pubmed/30649960

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