Intermittent Hypoxia

intermittent hypoxia graph v1

Programmed control of dynamic oxygen conditions permit a range of biological modeling possibilities. Chambers for in vitro and in vivo exposures permit highly reproducible experiments using intermittent hypoxia (IH), acute intermittent hypoxia (AIH), episodic hypoxia, and chronic intermittent hypoxia (CIH). These studies advance scientific understanding of human disease, disorders, and conditions like:

  • obstructive sleep apnea (OSA)
  • apnea of prematurity
  • hypertension
  • oxidative stress
  • inflammation
  • diabetes
  • obesity
  • neurodegeneration (Alzheimer’s and Parkinson’s)

Therapeutic models of IH are aimed at increasing motor function following spinal cord injury (SCI) or promoting neurogenesis to offset cognitive decline.