/** * WPForms Custom Honeypot * * @author Bill Erickson * @link http://www.billerickson.net/eliminate-spam-with-a-custom-honeypot/ * * @param string $honeypot, empty if not spam, honeypot text is used in WPForms Log * @param array $fields * @param array $entry * @param array $form_data */ function be_wpforms_custom_honeypot( $honeypot, $fields, $entry, $form_data ) { $honeypot_class = 'my-bio-field'; $honey_field = false; foreach( $form_data['fields'] as $form_field ) { if( false !== strpos( $form_field['css'], $honeypot_class ) ) { $honey_field = absint( $form_field['id'] ); } } if( !empty( $entry['fields'][$honey_field] ) ) { $honeypot = 'Custom honeypot'; } return $honeypot; } add_filter( 'wpforms_process_honeypot', 'be_wpforms_custom_honeypot', 10, 4 );

Closed incubators
and hoods for physiologically
relevant in vitro toxicology

STRUGGLING TO GET RESULTS THAT PREDICT HUMAN RISK?

Most labs aren’t equipped with tools for controlling oxygen. Room air conditions add ROS artifact to cell-based toxicological assays. This reduces the predictive capacity of tox assays, wasting precious time and money. Cell-based NAMs need protection from room air to accurately assess human risk.

Get the right equipment for controlling in vitro conditions that mimic in vivo temperature and oxygen levels full-time.

Options for Reducing Variability in Physioxia and Temperature for Cell-Based Tox Assays.

Upgrade your traditional CO2 incubator with hypoxic chambers

BioSpherix

Replace your incubator and BSC with a closed cell incubation and handling chamber

BioSpherix

How do I get cytocentric equipment FOR controlling OXYGEN LEVELS FOR TOXICOLOGY?

Step 1

TELL US ABOUT YOUR ASSAY

Step 2

LET US HELP YOU REFINE OR REPLACE YOUR INCUBATOR WITH CYTOCENTRIC EQUIPMENT

Step 3

Get quality results

Search 3300+ customer research publications citing BioSpherix equipment

Publications

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Piossek F, et al. Physiological oxygen and co-culture with human fibroblasts facilitate in vivo-like properties in human renal proximal tubular epithelial cells. Chem Biol Interact. 2022 Jul 1;361:109959.

Bordt EA. The importance of controlling in vitro oxygen tension to accurately model in vivo neurophysiology. Neurotoxicology. 2018 May;66:213-220.

Coyle JP, et al. Reduced oxygen tension culturing conditionally alters toxicogenic response of differentiated H9c2 cardiomyoblasts to acrolein. Toxicol Mech Methods. 2018 Sep;28(7):488-498.

Nzou G, et al. Human Cortex Spheroid with a Functional Blood Brain Barrier for High-Throughput Neurotoxicity Screening and Disease Modeling. Sci Rep. 2018 May 9;8(1):7413.

Blog Posts

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Cytocentric Blog – Interview with Cytocentric Visionary: Ian Mudway, Lecturer – Respiratory Toxicology Lung Biology Group , King’s College London

Part One: What Are the Fundamental Things That We Absolutely Have To Get Right?

Part Two: Taking a Career Risk for Better Cell Culture and Better Science

Part Three: We Will Know We Have Gotten Through When People Complain About the Difficulties of Publishing Data Generated under Atmospheric Oxygen

Posters

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Society of Toxicology – Supraphysioxic Room Air Adaptation of Human Lung A549 Cells Affects Silver Nanoparticle Toxicity Assays

In the future, tears won’t accompany a diagnosis because

researchers will unlock the full potential of living cells to:

Reveal Truths

Discover Therapies

Heal Humans