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• 1 Geng, H., et al. (2022). miR-431-5p regulates apoptosis of cardiomyocytes after acute myocardial infarction via targeting selenoprotein T. Physiol Res.
• 2 He, Y., et al. (2022). Pachymic Acid Ameliorates Pulmonary Hypertension by Regulating Nrf2-Keap1-ARE Pathway. Curr Med Sci 42(1): 56-67.
• 3 Hou, Y., et al. (2022). Mechanism of SMND-309 against lung injury induced by chronic intermittent hypoxia. Int Immunopharmacol 105: 108576.
• 4 Klaska, I. P., et al. (2022). Intravitreal administration of recombinant human opticin protects against hyperoxia-induced pre-retinal neovascularization. Exp Eye Res 215: 108908.
• 5 Paco-Meza, L.-M., et al. (2022). Identification of molecular pathways and protein-protein interactions in adipose tissue-derived mesenchymal stromal cells (ASCs) under physiological oxygen concentration in a diabetic rat model. Iranian Journal of Basic Medical Sciences 25(2)
• 6 Penumatsa, K. C., et al. (2022). Vascular smooth muscle ROCK1 contributes to hypoxia-induced pulmonary hypertension development in mice. Biochemical and biophysical research communications 604: 137-143.
• 7 Wilson, M. L., et al. (2022). Effects of Anesthesia on Ozone-Induced Lung and Systemic Inflammation. Lung.
• 8 Xu, Y., et al. (2022). miR-485-5p alleviates obstructive sleep apnea syndrome with hypertension by inhibiting PI3K/AKT signaling pathway via downregulating HIF3A expression. Sleep Breath: 1-11.
• 9 Yang, J., et al. (2022). Hepatoma‐derived growth factor is associated with pulmonary vascular remodeling and PAH disease severity and survival. Pulmonary Circulation 12(1): e12007.
• 10 Zheng, Z., et al. (2022). Gene losses may contribute to subterranean adaptations in naked mole-rat and blind mole-rat. BMC biology 20(1): 1-17
• 11 AlMarabeh, S., et al. (2022). Intrarenal pelvic bradykinin-induced sympathoexcitatory reno-renal reflex is attenuated in rats exposed to chronic intermittent hypoxia. Journal of hypertension 40(1): 46-64
• 12 Bastarache, J. A., et al. (2022). A two-hit model of sepsis plus hyperoxia causes lung permeability and inflammation. Am J Physiol Lung Cell Mol Physiol 322(2): L273-L282.
• 13 Beckmann, L., et al. (2022). Regulatory T Cells Contribute to Sexual Dimorphism in Neonatal Hypoxic-Ischemic Brain Injury. Stroke 53(2): 381-390.
• 14 Bensaid, S., et al. (2022). Oxygen supplementation to limit hypoxia-induced muscle atrophy in C2C12 myotubes: comparison with amino acid supplement and electrical stimulation. Cell Tissue Res 387(2): 287-301.
• 15 Camacho-Hernandez, P., et al. (2022). Perinatal inflammation and gestational intermittent hypoxia disturbs respiratory rhythm generation and long-term facilitation in vitro: Partial protection by acute minocycline. Respir Physiol Neurobiol 297: 103829.
• 16 Carmona, M., et al. (2022). Hypoxia preconditioning increases the ability of healthy but not diabetic rat-derived adipose stromal/stem cells (ASC) to improve histological lesions of streptozotocin-induced diabetic nephropathy. Pathol Res Pract 230: 153756.
• 17 Clees, A.-S., et al. (2022). Identification of the Cysteine Protease Legumain as a Potential Chronic Hypoxia-Specific Multiple Myeloma Target Gene. Cells 11(2): 292
• 18 Cluff, E., et al. (2022). Hypoxia-inducible factor-1 alpha expression is induced by IL-2 via the PI3K/mTOR pathway in hypoxic NK cells and supports effector functions in NKL cells and ex vivo expanded NK cells. Cancer Immunol Immunother.
• 19 Cole, H. D., et al. (2022). Fine-Feature Modifications to Strained Ruthenium Complexes Radically Alter Their Hypoxic Anticancer Activity(dagger). Photochem Photobiol 98(1): 73-84.
• 20 Cui, T. X., et al. (2022). Gelsolin Attenuates Neonatal Hyperoxia-Induced Inflammatory Responses to Rhinovirus Infection and Preserves Alveolarization. Frontiers in Immunology 13.
• 21 Danielpour, D., et al. (2022). Hypoxia represses early responses of prostate and renal cancer cells to YM155 independent of HIF-1alpha and HIF-2alpha. Curr Res Pharmacol Drug Discov 3: 100076.
• 22 Dupont, M., et al. (2022). Autophagy Targeting and Hematological Mobilization in FLT3-ITD Acute Myeloid Leukemia Decrease Repopulating Capacity and Relapse by Inducing Apoptosis of Committed Leukemic Cells. Cancers (Basel) 14(2): 453.
• 23 Fouda, A. Y., et al. (2022). Preclinical investigation of Pegylated arginase 1 as a treatment for retina and brain injury. Exp Neurol 348: 113923.
• 24 Ganouna-Cohen, G., et al. (2022). Additive effects of orchiectomy and intermittent hypoxia on lung mechanics and inflammation in C57BL/6J male mice. Exp Physiol 107(1): 68-81.
• 25 Gierhardt, M., et al. (2022). Genetic deletion of p66shc and/or cyclophilin D results in decreased pulmonary vascular tone. Cardiovasc Res 118(1): 305-315.
• 26 He, Y., et al. (2022). Optimal Efficacy and Safety of Humanized Anti-Scg3 Antibody to Alleviate Oxygen-Induced Retinopathy. International journal of molecular sciences 23(1): 350.
• 27 Huang, Z., et al. (2022). AD-16 Protects Against Hypoxic-Ischemic Brain Injury by Inhibiting Neuroinflammation. Neurosci Bull.
• 28 Im, J., et al. (2022). Normobaric hyperoxia re-sensitizes paclitaxel-resistant lung cancer cells. Molecular & Cellular Toxicology.
• 29 Ismaeel, A., et al. (2022). Endothelial cell-derived pro-fibrotic factors increase TGF-beta1 expression by smooth muscle cells in response to cycles of hypoxia-hyperoxia. Biochim Biophys Acta Mol Basis Dis 1868(1): 166278.
• 30 Labuz, D. F., et al. (2022). Intrauterine Growth Restriction (IUGR) as a Potential Target for Transamniotic Stem Cell Therapy. Journal of pediatric surgery.
• 31 Lana, D., et al. (2022). Hypoxia/Ischemia-Induced Rod Microglia Phenotype in CA1 Hippocampal Slices. International journal of molecular sciences 23(3): 1422.
• 32 Li, C., et al. (2022). Under-Oil Autonomously Regulated Oxygen Microenvironments: A Goldilocks Principle-Based Approach for Microscale Cell Culture. Adv Sci (Weinh) n/a(n/a): e2104510.
• 33 Li, D., et al. (2022). Abnormal lipid droplets accumulation induced cognitive deficits in obstructive sleep apnea syndrome mice via JNK/SREBP/ACC pathway but not through PDP1/PDC pathway. Mol Med 28(1): 3.
• 34 Li, X., et al. (2022). Hypoxia-induced lncRNA RBM5-AS1 promotes tumorigenesis via activating Wnt/beta-catenin signaling in breast cancer. Cell Death Dis 13(2): 95.
• 35 Liu, W., et al. (2022). Long non-coding RNA muscleblind like splicing regulator 1 antisense RNA 1 (LncRNA MBNL1-AS1) promotes the progression of acute myocardial infarction by regulating the microRNA-132-3p/SRY-related high-mobility-group box 4 (SOX4) axis. Bioengineered 13(1): 1424-1435.
• 36 Liu, W., et al. (2022). Rapamycin ameliorates chronic intermittent hypoxia and sleep deprivation-induced renal damage via the mammalian target of rapamycin (mTOR)/NOD-like receptor protein 3 (NLRP3) signaling pathway. Bioengineered 13(3): 5537-5550.
• 37 Lu, M., et al. (2022). Mineralocorticoid Receptor Antagonist Treatment of Established Pulmonary Arterial Hypertension Improves Interventricular Dependence in SU5416-Hypoxia Rat Model. Am J Physiol Lung Cell Mol Physiol 0(0): null.
• 38 Ma, C., et al. (2022). Ubiquitinated AIF is a major mediator of hypoxia-induced mitochondrial dysfunction and pulmonary artery smooth muscle cell proliferation. Cell Biosci 12(1): 9.
• 39 Osinski, V., et al. (2022). Loss of Id3 (Inhibitor of Differentiation 3) Increases the Number of IgM-Producing B-1b Cells in Ischemic Skeletal Muscle Impairing Blood Flow Recovery During Hindlimb Ischemia. Arterioscler Thromb Vasc Biol 42(1): 6-18.
• 40 Ozgur, B., et al. (2022). Hypoxia increases expression of selected blood-brain barrier transporters GLUT-1, P-gp, SLC7A5 and TFRC, while maintaining barrier integrity, in brain capillary endothelial monolayers. Fluids Barriers CNS 19(1): 1.
• 41Pavlatovská, B., et al. (2022). Lactic Acidosis Interferes With Toxicity of Perifosine to Colorectal Cancer Spheroids: Multimodal Imaging Analysis. Front Oncol: 2527
• 42 Peeples, E. S., et al. (2022). Temporal brain microRNA expression changes in a mouse model of neonatal hypoxic-ischemic injury. Pediatr Res 91(1): 92-100.
• 43 Purandare, N., et al. (2022). Intraperitoneal Triamcinolone Reduces Postoperative Adhesions, Possibly through Alteration of Mitochondrial Function. Journal of clinical medicine 11(2): 301
• 44 Ravizzoni Dartora, D., et al. (2022). Cardiac Left Ventricle Mitochondrial Dysfunction After Neonatal Exposure to Hyperoxia: Relevance for Cardiomyopathy After Preterm Birth. Hypertension: HYPERTENSIONAHA. 121.17979
• 45 Reddy, N. M., et al. (2022). Nrf2 Is Required for Optimal Alveolar-Macrophage-Mediated Apoptotic Neutrophil Clearance after Oxidant Injury. Antioxidants 11(2): 212.
• 46 Ryan, R. M., et al. (2022). Oxygen and steroids affect the regulatory role of natriuretic peptide receptor-C on surfactant secretion by type II cells. Am J Physiol Lung Cell Mol Physiol 322(1): L13-L22.
• 47 Salazar, C., et al. (2022). Dynamic Distribution of HIG2A between the Mitochondria and the Nucleus in Response to Hypoxia and Oxidative Stress. International journal of molecular sciences 23(1): 389.
• 48 Smith, T. L., et al. (2022). eNOS controls angiogenic sprouting and retinal neovascularization through the regulation of endothelial cell polarity. Cellular and Molecular Life Sciences 79(1): 1-18
• 49 Snyder, B., et al. (2022). Aged Mouse Hippocampus Exhibits Signs of Chronic Hypoxia and an Impaired HIF-Controlled Response to Acute Hypoxic Exposures. Cells 11(3): 423.
• 50 Šranková, M., et al. (2022). Antiproliferative and Cytotoxic Activities of Fluorescein—A Diagnostic Angiography Dye. International journal of molecular sciences 23(3): 1504
• 51 Szojka, A. R. A., et al. (2022). Time course of 3D fibrocartilage formation by expanded human meniscus fibrochondrocytes in hypoxia. J Orthop Res 40(2): 495-503.
• 52 Tao, Y., et al. (2022). Long noncoding RNA LUCAT1 enhances the survival and therapeutic effects of mesenchymal stromal cells post-myocardial infarction. Mol Ther Nucleic Acids 27: 412-426.
• 53 Vandenberg, G. G., et al. (2022). Mitochondrial bioenergetics of astrocytes in Fragile X syndrome: new perspectives on culture conditions and sex effects. Am J Physiol Cell Physiol 322(2): C125-C135.
• 54 Won, T., et al. (2022). Endothelial thrombomodulin downregulation caused by hypoxia contributes to severe infiltration and coagulopathy in COVID-19 patient lungs. EBioMedicine 75: 103812.
• 55 Xu, P., et al. (2022). Erythrocyte transglutaminase-2 combats hypoxia and chronic kidney disease by promoting oxygen delivery and carnitine homeostasis. Cell Metab 34(2): 299-316 e296.
• 56 Xu, Y., et al. (2022). A novel regulatory mechanism network mediated by lncRNA TUG1 that induces the impairment of spiral artery remodeling in Preeclampsia. Mol Ther.
• 57 Yang, K., et al. (2022). Lactate promotes macrophage HMGB1 lactylation, acetylation, and exosomal release in polymicrobial sepsis. Cell Death Differ 29(1): 133-146.
• 58 Zhang, G., et al. (2022). Sulforaphane Does Not Protect Right Ventricular Systolic and Diastolic Functions in Nrf2 Knockout Pulmonary Artery Hypertension Mice. Cardiovasc Drugs Ther.
• 59 Zhang, J. S., et al. (2022). microRNA-455-5p alleviates neuroinflammation in cerebral ischemia/reperfusion injury. Neural Regen Res 17(8): 1769-1775.
• 60 Zhang, J., et al. (2022). Hypoxia promotes steroidogenic competence of buffalo (Bubalus bubalis) theca cells. Theriogenology 180: 113-120.
• 61 Zhao, C., et al. (2022). Dynamic Multiscale Regulation of Perfusion Recovery in Experimental Peripheral Arterial Disease: A Mechanistic Computational Model. JACC Basic Transl Sci 7(1): 28-50.
• 62 Adams, K. V., et al. (2021). Constraint-induced movement therapy promotes motor recovery after neonatal stroke in the absence of neural precursor activation. Eur J Neurosci 53(4): 1334-1349.
• 63 Aghajanian, A., et al. (2021). Decreased inspired oxygen stimulates de novo formation of coronary collaterals in adult heart. J Mol Cell Cardiol 150: 1-11.
• 64 Al Khazal, F., et al. (2021). Unexpected obesity, rather than tumorigenesis, in a conditional mouse model of mitochondrial complex II deficiency. FASEB J 35(2): e21227.
• 65 Alhalhooly, L., et al. (2021). Dynamic cellular biomechanics in responses to chemotherapeutic drug in hypoxia probed by atomic force spectroscopy. Oncotarget 12(12): 1165-1177.
• 66 Al-Hilal, T. A., et al. (2021). Design, synthesis and biological evaluations of a long-acting, hypoxia-activated prodrug of fasudil, a ROCK inhibitor, to reduce its systemic side-effects. J Control Release 334: 237-247.
• 67 Alicea-Torres, K., et al. (2021). Immune suppressive activity of myeloid-derived suppressor cells in cancer requires inactivation of the type I interferon pathway. Nat Commun 12(1): 1717.
• 68 Allan, K. C., et al. (2021). Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function. Cell Stem Cell 28(2): 257-272 e211.
• 69 Allmon, E., et al. (2021). The influence of hypoxia on the cardiac transcriptomes of two estuarine species – C. variegatus and F. grandis. Comp Biochem Physiol Part D Genomics Proteomics 39: 100837.
• 70 AlMarabeh, S., et al. (2021). Chronic intermittent hypoxia impairs diuretic and natriuretic responses to volume expansion in rats with preserved low-pressure baroreflex control of the kidney. Am J Physiol Renal Physiol 320(1): F1-F16.
• 71 Alzahrani, A. A., et al. (2021). beta-Adrenoceptor blockade prevents carotid body hyperactivity and elevated vascular sympathetic nerve density induced by chronic intermittent hypoxia. Pflugers Arch 473(1): 37-51.
• 72 Amin, S. M., et al. (2021). Efficacy of Aflibercept Treatment and Its Effect on the Retinal Perfusion in the Oxygen-Induced Retinopathy Mouse Model of Retinopathy of Prematurity. Ophthalmic Res 64(1): 91-98.
• 73 Arce, C., et al. (2021). Hypoxia Increases Nitric Oxide-Dependent Inhibition of Angiogenic Growth. International Journal of Translational Medicine 1(3): 366-380.
• 74 Arias-Reyes, C., et al. (2021). Mice and Rats Display Different Ventilatory, Hematological, and Metabolic Features of Acclimatization to Hypoxia. Front Physiol 12: 647822.
• 75 Atala, A., et al. (2021). Regen med therapeutic opportunities for fighting COVID-19. Stem Cells Transl Med 10(1): 5-13.
• 76 Bapat, A., et al. (2021). Hypoxia promotes erythroid differentiation through the development of progenitors and proerythroblasts. Exp Hematol 97: 32-46 e35.
• 77 Barreto-Duran, E., et al. (2021). 3D Multicellular Spheroid for the Study of Human Hematopoietic Stem Cells: Synergistic Effect Between Oxygen Levels, Mesenchymal Stromal Cells and Endothelial Cells. Journal of Blood Medicine 12: 517.
• 78 Bazilio, D. S., et al. (2021). Distinct cardiovascular and respiratory responses to short-term sustained hypoxia in juvenile Sprague Dawley and Wistar Hannover rats. Auton Neurosci 230: 102746.
• 79 Berghausen, E. M., et al. (2021). Disrupted PI3K subunit p110alpha signaling protects against pulmonary hypertension and reverses established disease in rodents. J Clin Invest 131(19).
• 80Bernhard, J. M., et al. (2021). Impacts of multiple stressors on a benthic foraminiferal community: A long-term experiment assessing response to ocean acidification, hypoxia and warming. Frontiers in Marine Science
• 81 Bodkin, D., et al. (2021). Neonatal intermittent hypoxia, fish oil, and/or antioxidant supplementation on gut microbiota in neonatal rats. Pediatr Res.
• 82 Cahill, L. S., et al. (2021). Sex differences in modulation of fetoplacental vascular resistance in growth-restricted mouse fetuses following betamethasone administration: comparisons with human fetuses. Am J Obstet Gynecol MFM 3(1): 100251.
• 83 Cai, C., et al. (2021). Lymphocytic microparticles suppress retinal angiogenesis via targeting Muller cells in the ischemic retinopathy mouse model. Exp Cell Res 399(2): 112470.
• 84 Cao, X., et al. (2021). TRB3 mediates vascular remodeling by activating the MAPK signaling pathway in hypoxic pulmonary hypertension. Respir Res 22(1): 312.
• 85 Casalino-Matsuda, S. M., et al. (2021). Hypercapnia selectively modulates LPS-induced changes in innate immune and DNA replication-related gene transcription in the macrophage. Interface Focus 11(2): 20200039.
• 86 Castillo, M. C., et al. (2021). NIN-like protein7 and PROTEOLYSIS6 functional interaction enhances tolerance to sucrose, ABA, and submergence. Plant Physiol 187(4): 2731-2748.
• 87 Chandran, R. R., et al. (2021). Distinct roles of KLF4 in mesenchymal cell subtypes during lung fibrogenesis. Nat Commun 12(1): 7179.
• 88 Chang, C. C., et al. (2021). Three-dimensional Imaging Coupled with Topological Quantification Uncovers Retinal Vascular Plexuses Undergoing Obliteration. Theranostics 11(3): 1162-1175.
• 89 Chang, J., et al. (2021). Intrauterine growth restriction followed by oxygen support uniquely interferes with genetic regulators of myelination. eneuro.
• 90 Chaubey, S., et al. (2021). alpha1,3-Fucosyltransferase-IX, an enzyme of pulmonary endogenous lung stem cell marker SSEA-1, alleviates experimental bronchopulmonary dysplasia. Pediatr Res 89(5): 1126-1135.
• 91 Chen, C. M., et al. (2021). Immunization with anti-Tn immunogen in maternal rats protects against hyperoxia-induced kidney injury in newborn offspring. Pediatr Res 89(3): 476-482.
• 92 Chen, C. M., et al. (2021). Maternal antibiotic exposure disrupts microbiota and exacerbates hyperoxia-induced lung injury in neonatal mice. Pediatr Res 90(4): 776-783.
• 93 Chen, J. E., et al. (2021). Matrix Hyaluronic Acid and Hypoxia Influence a CD133(+) Subset of Patient-Derived Glioblastoma Cells. Tissue Eng Part A 0(ja): null.
• 94 Chen, J., et al. (2021). A drug-tunable Flt23k gene therapy for controlled intervention in retinal neovascularization. Angiogenesis 24(1): 97-110.
• 95 Chen, J., et al. (2021). Exploiting the acquired vulnerability of cisplatin-resistant tumors with a hypoxia-amplifying DNA repair–inhibiting (HYDRI) nanomedicine. Sci Adv 7(13): eabc5267.
• 96 Chen, J., et al. (2021). The protective role of SOD1 overexpression in central mediation of bradycardia following chronic intermittent hypoxia in mice. Am J Physiol Regul Integr Comp Physiol 320(3): R317-R330.
• 97 Chen, L., et al. (2021). Chronic Exposure to Hypoxia Inhibits Myelinogenesis and Causes Motor Coordination Deficits in Adult Mice. Neurosci Bull 37(10): 1397-1411.
• 98 Chen, Y., et al. (2021). The lncRNA Malat1 regulates microvascular function after myocardial infarction in mice via miR-26b-5p/Mfn1 axis-mediated mitochondrial dynamics. Redox Biol 41: 101910.
• 99 Cheng, W. H., et al. (2021). Hypoxia-induced preadipocyte factor 1 expression in human lung fibroblasts through ERK/PEA3/c-Jun pathway. Mol Med 27(1): 69.
• 100 Cheng, W. H., et al. (2021). Pref-1 induced lung fibroblast differentiation by hypoxia through integrin alpha5beta1/ERK/AP-1 cascade. Eur J Pharmacol 909: 174385.
• 101 Chiang, C. T., et al. (2021). High-throughput microscopy reveals the impact of multifactorial environmental perturbations on colorectal cancer cell growth. GigaScience 10(4): giab026.
• 102 Cho, H., et al. (2021). Dendrimer-Triamcinolone Acetonide Reduces Neuroinflammation, Pathological Angiogenesis, and Neuroretinal Dysfunction in Ischemic Retinopathy. Adv Ther (Weinh) 4(2): 2000181.
• 103 Christou, H., et al. (2021). Carbonic anhydrase inhibition improves pulmonary artery reactivity and nitric oxide-mediated relaxation in sugen-hypoxia model of pulmonary hypertension. Am J Physiol Regul Integr Comp Physiol 320(6): R835-R850.
• 104 Clapper, E., et al. (2021). The regulation of bcr-abl in hypoxia is through the mTOR pathway. Leukemia & Lymphoma 62(4): 967-978
• 105 Cole, H. D., et al. (2021). Anticancer Agent with Inexplicable Potency in Extreme Hypoxia: Characterizing a Light-Triggered Ruthenium Ubertoxin. J Am Chem Soc.
• 106 Compton, S. L. E., et al. (2021). Adaptation of metabolism to multicellular aggregation, hypoxia and obese stromal cell incorporation as potential measure of survival of ovarian metastases. Exp Cell Res 399(1): 112397.
• 107 Cooper, J. F., et al. (2021). Stress increases in exopher-mediated neuronal extrusion require lipid biosynthesis, FGF, and EGF RAS/MAPK signaling. Proc Natl Acad Sci U S A 118(36).
• 108 Correia, M. J., et al. (2021). Aryl Hydrocarbon Receptor and Cysteine Redox Dynamics Underlie (Mal)adaptive Mechanisms to Chronic Intermittent Hypoxia in Kidney Cortex. Antioxidants (Basel) 10(9): 1484.
• 109 Cortese, R., et al. (2021). Gestational sleep apnea perturbations induce metabolic disorders by divergent epigenomic regulation. Epigenomics 13(10): 751-765.
• 110 Coyle, R. C., et al. (2021). Targeting HIF-alpha for robust prevascularization of human cardiac organoids. J Tissue Eng Regen Med 15(2): 189-202.
• 111 Cui, T. X., et al. (2021). Lung CD103(+)dendritic cells and Clec9a signaling are required for neonatal hyperoxia-induced inflammatory responses to rhinovirus infection. Am J Physiol Lung Cell Mol Physiol 320(2): L193-L204.
• 112 Cyr-Depauw, C., et al. (2021). Characterization of the innate immune response in a novel murine model mimicking bronchopulmonary dysplasia. Pediatr Res 89(4): 803-813.
• 113 da Silva, M. P., et al. (2021). Chronic intermittent hypoxia increases excitability and synaptic excitation of protrudor and retractor hypoglossal motoneurones. J Physiol 599(6): 1917-1932.
• 114 Dai, W., et al. (2021). Effects of Op2113 on Myocardial Infarct Size and No Reflow in a Rat Myocardial Ischemia/reperfusion Model. Cardiovascular Drugs and Therapy: 1-11
• 115 Dani, C., et al. (2021). Neurotoxicity of Unconjugated Bilirubin in Neonatal Hypoxic-Ischemic Brain Injury in vitro. Front Pediatr 9: 659477.
• 116 Das, P., et al. (2021). Chitin-Derived AVR-48 Prevents Experimental Bronchopulmonary Dysplasia (BPD) and BPD-Associated Pulmonary Hypertension in Newborn Mice. Int J Mol Sci 22(16): 8547.
• 117 Deprez, A., et al. (2021). Transient neonatal exposure to hyperoxia, an experimental model of preterm birth, leads to skeletal muscle atrophy and fiber type switching. Clin Sci (Lond) 135(22): 2589-2605.
• 118 Desjarlais, M., et al. (2021). Tyrosine-Protein Phosphatase Non-receptor Type 9 (PTPN9) Negatively Regulates the Paracrine Vasoprotective Activity of Bone-Marrow Derived Pro-angiogenic Cells: Impact on Vascular Degeneration in Oxygen-Induced Retinopathy. Front Cell Dev Biol 9: 679906.
• 119 Dias, G. F., et al. (2021). Uremia and Inadequate Oxygen Supply Induce Eryptosis and Intracellular Hypoxia in Red Blood Cells. Cell Physiol Biochem 55(4): 449-459.
• 120 Díaz-García, E., et al. (2021). Intermittent Hypoxia Mediates Paraspeckle Protein-1 Upregulation in Sleep Apnea. Cancers 13(15): 3888.
• 121 Dizin, E., et al. (2021). Activation of the Hypoxia-Inducible Factor Pathway Inhibits Epithelial Sodium Channel–Mediated Sodium Transport in Collecting Duct Principal Cells. Journal of the American Society of Nephrology 32(12): 3130-3145
• 122 Domingos-Souza, G., et al. (2021). Alpha adrenergic receptor signaling in the hypothalamic paraventricular nucleus is diminished by the chronic intermittent hypoxia model of sleep apnea. Exp Neurol 335: 113517.
• 123 Domogauer, J. D., et al. (2021). Acquired radioresistance in cancer associated fibroblasts is concomitant with enhanced antioxidant potential and DNA repair capacity. Cell Commun Signal 19(1): 30.
• 124 Dong, D., et al. (2021). Hyperoxia sensitizes hypoxic HeLa cells to ionizing radiation by downregulating HIF1alpha and VEGF expression. Mol Med Rep 23(1).
• 125 Drummond, S. E., et al. (2021). The role of NADPH oxidase in chronic intermittent hypoxia-induced respiratory plasticity in adult male mice. Respir Physiol Neurobiol 292: 103713.
• 126 Dumas, P. Y., et al. (2021). Dual Inhibition of FLT3 and AXL by Gilteritinib Overcomes Hematopoietic Niche-Driven Resistance Mechanisms in FLT3-ITD Acute Myeloid Leukemia. Clin Cancer Res 27(21): 6012-6025.
• 127 Dvořák, A., et al. (2021). The effects of bilirubin and lumirubin on metabolic and oxidative stress markers. Frontiers in pharmacology 12: 26
• 128 Dwight, T., et al. (2021). Functional significance of germline EPAS1 variants. Endocr Relat Cancer 28(2): 97-109.
• 129 Dykstra, K. M., et al. (2021). Inhibiting autophagy targets human leukemic stem cells and hypoxic AML blasts by disrupting mitochondrial homeostasis. Blood Adv 5(8): 2087-2100.
• 130 Dzah, C. S., et al. (2021). Effects of pretreatment and type of hydrolysis on the composition, antioxidant potential and HepG2 cytotoxicity of bound polyphenols from Tartary buckwheat (Fagopyrum tataricum L. Gaerth) hulls. Food Res Int 142: 110187.
• 131 El Hafny-Rahbi, B., et al. (2021). Tumour angiogenesis normalized by myo-inositol trispyrophosphate alleviates hypoxia in the microenvironment and promotes antitumor immune response. J Cell Mol Med 25(7): 3284-3299.
• 132 Elkhenany, H. A., et al. (2021). Bone Marrow Mesenchymal Stem Cell-Derived Tissues are Mechanically Superior to Meniscus Cells. Tissue Eng Part A 27(13-14): 914-928.
• 133 Fachi, J. L., et al. (2021). Hypoxia enhances ILC3 responses through HIF-1alpha-dependent mechanism. Mucosal Immunol 14(4): 828-841.
• 134 Fang, Y. Y., et al. (2021). 7,8-Dihydroxyflavone protects retinal ganglion cells against chronic intermittent hypoxia-induced oxidative stress damage via activation of the BDNF/TrkB signaling pathway. Sleep Breath: 1-9.
• 135 Framnes-DeBoer, S. N., et al. (2021). The timing of intermittent hypoxia differentially affects macronutrient intake and energy substrate utilization in mice. Am J Physiol Endocrinol Metab 321(4): E543-E550.
• 136 Gabrielli, N. M., et al. (2021). TRAF2 is a novel ubiquitin E3 ligase for the Na, K-ATPase β-subunit that drives alveolar epithelial barrier dysfunction in hypercapnia. Frontiers in Cell and Developmental Biology 9: 1744
• 137 Gao, S., et al. (2021). Complement promotes endothelial von Willebrand factor and angiopoietin-2 release in obstructive sleep apnea. Sleep 44(4).
• 138 Garcia, D., et al. (2021). Short exposure to hyperoxia causes cultured lung epithelial cell mitochondrial dysregulation and alveolar simplification in mice. Pediatr Res 90(1): 58-65.
• 139 Gauthier, A. G., et al. (2021). The Positive Allosteric Modulation of alpha7-Nicotinic Cholinergic Receptors by GAT107 Increases Bacterial Lung Clearance in Hyperoxic Mice by Decreasing Oxidative Stress in Macrophages. Antioxidants (Basel) 10(1): 135.
• 140 Ge, H., et al. (2021). Ambroxol Upregulates Glucocerebrosidase Expression to Promote Neural Stem Cells Differentiation Into Neurons Through Wnt/β-Catenin Pathway After Ischemic Stroke. Frontiers in Molecular Neuroscience 13: 263
• 141 Gerace, E., et al. (2021). NIR Laser Photobiomodulation Induces Neuroprotection in an In Vitro Model of Cerebral Hypoxia/Ischemia. Mol Neurobiol 58(10): 5383-5395.
• 142 Getsy, P. M., et al. (2021). Carotid sinus nerve transection abolishes the facilitation of breathing that occurs upon cessation of a hypercapnic gas challenge in male mice. J Appl Physiol (1985) 131(2): 821-835.
• 143 Getsy, P. M., et al. (2021). Short-term facilitation of breathing upon cessation of hypoxic challenge is impaired in male but not female endothelial NOS knock-out mice. Sci Rep 11(1): 18346.
• 144 Getsy, P. M., et al. (2021). Ventilatory Responses During and Following Hypercapnic Gas Challenge are Impaired in Male but Not Female Endothelial NOS Knock-out Mice. Scientific Reports.
• 145 Ginerete, R. P., et al. (2021). Repeated episodes of transient reduction of oxygen exposure simulating aircraft cabin conditions enhance resilience to stress in mice. Eur J Neurosci 54(9): 7109-7124.
• 146 Głuszko, A., et al. (2021). Small Extracellular Vesicles from Head and Neck Squamous Cell Carcinoma Cells Carry a Proteomic Signature for Tumor Hypoxia. Cancers 13(16): 4176
• 147 Gomaa, F., et al. (2021). Multiple integrated metabolic strategies allow foraminiferan protists to thrive in anoxic marine sediments. Sci Adv 7(22): eabf1586.
• 148 Gong, J., et al. (2021). The pentose phosphate pathway mediates hyperoxia-induced lung vascular dysgenesis and alveolar simplification in neonates. JCI Insight 6(5).
• 149 Grant, G. J., et al. (2021). Enhanced epithelial sodium channel activity in neonatal Scnn1b mouse lung attenuates high oxygen-induced lung injury. Am J Physiol Lung Cell Mol Physiol 321(1): L29-L41.
• 150 Grant, Z. L., et al. (2021). The histone acetyltransferase HBO1 promotes efficient tip cell sprouting during angiogenesis. Development 148(20).
• 151 Gu, C., et al. (2021). Altered expression of ADM and ADM2 by hypoxia regulates migration of trophoblast and HLA-G expressiondagger. Biol Reprod 104(1): 159-169.
• 152 Gu, Y., et al. (2021). CTRP1 Aggravates Cardiac Dysfunction Post Myocardial Infarction by Modulating TLR4 in Macrophages. Front Immunol 12: 635267.
• 153 Gu, Y., et al. (2021). Neutrophil Gelatinase-Associated Lipocalin 2 Accelerates Hypoxia-Induced Endothelial Cell Injury via eNOS/NRF2 Signalling. Cell J 23(4): 435-444.
• 154 Guan, D., et al. (2021). The DpdtbA induced EMT inhibition in gastric cancer cell lines was through ferritinophagy-mediated activation of p53 and PHD2/hif-1alpha pathway. J Inorg Biochem 218: 111413.
• 155 Guduric-Fuchs, J., et al. (2021). miR-130a activates the VEGFR2/STAT3/HIF1alpha axis to potentiate the vasoregenerative capacity of endothelial colony-forming cells in hypoxia. Mol Ther Nucleic Acids 23: 968-981.
• 156 Guo, X., et al. (2021). O‑GlcNAcylation contributes to intermittent hypoxia‑associated vascular dysfunction via modulation of MAPKs but not CaMKII pathways. Molecular medicine reports 24(5): 1-12
• 157 Guzel, S., et al. (2021). Dose Response of Bumetanide on Aquaporins and Angiogenesis Biomarkers in Human Retinal Endothelial Cells Exposed to Intermittent Hypoxia. Pharmaceuticals (Basel) 14(10): 967.
• 158 Halder, S. K. and R. Milner (2021). The impact of chronic mild hypoxia on cerebrovascular remodelling; uncoupling of angiogenesis and vascular breakdown. Fluids Barriers CNS 18(1): 50.
• 159 Hao, S., et al. (2021). Chronic intermittent hypoxia promoted lung cancer stem cell-like properties via enhancing Bach1 expression. Respir Res 22(1): 58.
• 160 Harada, T., et al. (2021). Comprehensive analysis of sucrolytic enzyme gene families in carnation (Dianthus caryophyllus L.). Phytochemistry 185: 112607.
• 161 He, B., et al. (2021). Sevoflurane alleviates hepatic ischaemia/reperfusion injury by up-regulating miR-96 and down-regulating FOXO4. J Cell Mol Med.
• 162 He, Y., et al. (2021). Pachymic Acid Ameliorates Pulmonary Hypertension by Regulating Nrf2-Keap1-ARE Pathway. Curr Med Sci.
• 163 Heinisch, O., et al. (2021). Erythropoietin Abrogates Post-Ischemic Activation of the NLRP3, NLRC4, and AIM2 Inflammasomes in Microglia/Macrophages in a TAK1-Dependent Manner. Transl Stroke Res.
• 164 Hernandez-Soto, R., et al. (2021). Chronic intermittent hypoxia alters main olfactory bulb activity and olfaction. Exp Neurol 340: 113653.
• 165 Hong, C. R., et al. (2021). Spatially-resolved pharmacokinetic/pharmacodynamic modelling of bystander effects of a nitrochloromethylbenzindoline hypoxia-activated prodrug. Cancer Chemother Pharmacol 88(4): 673-687.
• 166 Hong, X., et al. (2021). Exogenous Wnt1 Prevents Acute Kidney Injury and Its Subsequent Progression to Chronic Kidney Disease. Front Physiol 12: 745816.
• 167 Horii, M., et al. (2021). Modeling preeclampsia using human induced pluripotent stem cells. Sci Rep 11(1): 5877.
• 168 Hossain, M. I., et al. (2021). Restoration of CTSD (cathepsin D) and lysosomal function in stroke is neuroprotective. Autophagy 17(6): 1330-1348.
• 169 Huang, L. T., et al. (2021). Roxadustat attenuates hyperoxia-induced lung injury by upregulating proangiogenic factors in newborn mice. Pediatr Neonatol 62(4): 369-378.
• 170 Huang, L. T., et al. (2021). TRIM72 mediates lung epithelial cell death upon hyperoxia exposure. J Chin Med Assoc 84(1): 79-86.
• 171 Huang, Z., et al. (2021). Nattokinase Attenuates Retinal Neovascularization Via Modulation of Nrf2/HO-1 and Glial Activation. Invest Ophthalmol Vis Sci 62(6): 25.
• 172 Hurskainen, M., et al. (2021). Single cell transcriptomic analysis of murine lung development on hyperoxia-induced damage. Nat Commun 12(1): 1565.
• 173 Igelmann, S., et al. (2021). A hydride transfer complex reprograms NAD metabolism and bypasses senescence. Mol Cell 81(18): 3848-3865 e3819.
• 174 Iqbal, K., et al. (2021). Catechol-O-methyltransferase and Pregnancy Outcome: an Appraisal in Rat. Reprod Sci 28(2): 462-469.
• 175 Jain, N., et al. (2021). Identification of Novel Endogenous Controls for qPCR Normalization in SK-BR-3 Breast Cancer Cell Line. Genes (Basel) 12(10).
• 176 Jain, P. P., et al. (2021). Halofuginone, a promising drug for treatment of pulmonary hypertension. Br J Pharmacol 178(17): 3373-3394.
• 177 Jain, P. P., et al. (2021). TRPC6, a therapeutic target for pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 321(6): L1161-L1182.
• 178 Joharapurkar, A., et al. (2021). Effect of dual PPAR-alpha/gamma agonist saroglitazar on diabetic retinopathy and oxygen-induced retinopathy. Eur J Pharmacol 899: 174032.
• 179 Joshi, S., et al. (2021). ACE2/ACE imbalance and impaired vasoreparative functions of stem/progenitor cells in aging. Geroscience 43(3): 1423-1436.
• 180 Kang, Z., et al. (2021). An L-2-hydroxyglutarate biosensor based on specific transcriptional regulator LhgR. Nat Commun 12(1): 3619.
• 181 Kassa, B., et al. (2021). Endothelial cell PHD2-HIF1alpha-PFKFB3 contributes to right ventricle vascular adaptation in pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 321(4): L675-L685.
• 182KAYMAZ, A. and S. Erimşah (2021). Evaluation of the effect of Carvacrol on retinal neovascularization in rats. Turkish Journal of Veterinary Research 5(1): 35-40
• 183 Kearon, J. E., et al. (2021). GDNF requires HIF-1alpha and RET activation for suppression of programmed cell death of enteric neurons by metabolic challenge. Mol Cell Neurosci 115: 103655.
• 184 Khalyfa, A., et al. (2021). Circulating exosomes and gut microbiome induced insulin resistance in mice exposed to intermittent hypoxia: Effects of physical activity. EBioMedicine 64: 103208.
• 185 Khalyfa, A., et al. (2021). Transcriptomic Changes of Murine Visceral Fat Exposed to Intermittent Hypoxia at Single Cell Resolution. International journal of molecular sciences 22(1): 261
• 186 Khawaja, R. R., et al. (2021). GluA2 overexpression in oligodendrocyte progenitors promotes postinjury oligodendrocyte regeneration. Cell Rep 35(7): 109147.
• 187 Kim, D., et al. (2021). Discovery of Novel Small-Molecule Antiangiogenesis Agents to Treat Diabetic Retinopathy. J Med Chem 64(9): 5535-5550.
• 188 Klaska, I. P., et al. (2021). Intravitreal administration of recombinant human opticin protects against hyperoxia-induced pre-retinal neovascularization. Exp Eye Res 215: 108908.
• 189 Kolb, T. M., et al. (2021). PDE9A deficiency does not prevent chronic-hypoxic pulmonary hypertension in mice. Physiol Rep 9(18): e15057.
• 190 Koritala, B. S. C., et al. (2021). Intermittent Hypoxia Alters the Circadian Expression of Clock Genes in Mouse Brain and Liver. Genes (Basel) 12(10): 1627.
• 191 Kouthouridis, S., et al. (2021). Oxygenation as a driving factor in epithelial differentiation at the air-liquid interface. Integr Biol (Camb) 13(3): 61-72.
• 192Kryvenko, V., et al. (2021). Hypercapnia-induces IRE1α-driven Endoplasmic Reticulum-associated Degradation of the Na, K-ATPase β-subunit. American Journal of Respiratory Cell and Molecular Biology(ja)
• 193 Kukumberg, M., et al. (2021). Hypoxia-induced amniotic fluid stem cell secretome augments cardiomyocyte proliferation and enhances cardioprotective effects under hypoxic-ischemic conditions. Sci Rep 11(1): 163.
• 194 Kvarik, T., et al. (2021). The Protective Effects of Endogenous PACAP in Oxygen-Induced Retinopathy. J Mol Neurosci 71(12): 2546-2557.
• 195 Laban, H., et al. (2021). NFAT5/TonEBP Limits Pulmonary Vascular Resistance in the Hypoxic Lung by Controlling Mitochondrial Reactive Oxygen Species Generation in Arterial Smooth Muscle Cells. Cells 10(12): 3293.
• 196 Ladak, Z., et al. (2021). Sulforaphane (SFA) protects neuronal cells from oxygen & glucose deprivation (OGD). PLOS ONE 16(3): e0248777.
• 197 Larcombe, A. N., et al. (2021). Mouse Lung Structure and Function after Long-Term Exposure to an Atmospheric Carbon Dioxide Level Predicted by Climate Change Modeling. Environ Health Perspect 129(1): 17001.
• 198 Lee, D. E., et al. (2021). Cancer-induced Cardiac Atrophy Adversely Affects Myocardial Redox State and Mitochondrial Oxidative Characteristics. JCSM Rapid Commun 4(1): 3-15.
• 199 Lee, R. H., et al. (2021). Activation of Neuropeptide Y2 Receptor Can Inhibit Global Cerebral Ischemia-Induced Brain Injury. Neuromolecular Med.
• 200Lee, S. J., et al. (2021). Specific ablation of PDGFRβ-overexpressing pericytes with antibody-drug conjugate potently inhibits pathologic ocular neovascularization in mouse models. Communications Medicine 1(1): 1-12
• 201 Li, C., et al. (2021). Annexin A2 promotes development of retinal neovascularization through PI3K/ AKT signaling pathway. Curr Eye Res: 1-11.
• 202 Li, L., et al. (2021). Salidroside Ameliorated Intermittent Hypoxia-Aggravated Endothelial Barrier Disruption and Atherosclerosis via the cAMP/PKA/RhoA Signaling Pathway. Front Pharmacol 12: 723922.
• 203 Li, Q., et al. (2021). Small extracellular vesicles containing miR-486-5p promote angiogenesis after myocardial infarction in mice and nonhuman primates. Sci Transl Med 13(584): eabb0202.
• 204 Li, R., et al. (2021). Autophagy is required for the promoting effect of angiogenic factor with G patch domain and forkhead-associated domain 1 (AGGF1) in retinal angiogenesis. Microvasc Res 138: 104230.
• 205 Li, Y., et al. (2021). Extracellular vesicle microRNA cargoes from intermittent hypoxia-exposed cardiomyocytes and their effect on endothelium. Biochem Biophys Res Commun 548: 182-188.
• 206 Liang, L., et al. (2021). Exosomes derived from miR-301a-3p-overexpressing adipose-derived mesenchymal stem cells reverse hypoxia-induced erectile dysfunction in rat models. Stem Cell Res Ther 12(1): 87.
• 207 Liang, R., et al. (2021). The Stress-Inducible BCL2A1 Is Required for Ovarian Cancer Metastatic Progression in the Peritoneal Microenvironment. Cancers (Basel) 13(18).
• 208 Lignelli, E., et al. (2021). The H2S-generating enzyme 3-mercaptopyruvate sulfurtransferase regulates pulmonary vascular smooth muscle cell migration and proliferation but does not impact normal or aberrant lung development. Nitric Oxide 107: 31-45.
• 209 Lin, Y., et al. (2021). Environmental enrichment implies GAT-1 as a potential therapeutic target for stroke recovery. Theranostics 11(8): 3760-3780.
• 210 Linge, M., et al. (2021). Systematic analysis of candidate reference genes for gene expression analysis in hyperoxia-based mouse models of bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol 321(4): L718-L725.
• 211 Liu, J., et al. (2021). Hypoxic postconditioning-induced neuroprotection increases neuronal autophagy via activation of the SIRT1/FoxO1 signaling pathway in rats with global cerebral ischemia. Exp Ther Med 22(1): 695.
• 212 Liu, L., et al. (2021). Effect of synthetic oxygen-generating system on cell survival under hypoxic condition in vitro. J Biomater Sci Polym Ed 32(8): 967-979.
• 213 Liu, M., et al. (2021). Transforming Growth Factor-induced Protein Promotes NF-kappaB-mediated Angiogenesis during Postnatal Lung Development. Am J Respir Cell Mol Biol 64(3): 318-330.
• 214 Liu, Q., et al. (2021). The Agonist of Inward Rectifier Potassium Channel (IK1) Attenuates Rat Reperfusion Arrhythmias Linked to CaMKII Signaling. Int Heart J 62(6): 1348-1357.
• 215 Liu, X., et al. (2021). Proteomic Profiling Identifies Kaposi’s Sarcoma-Associated Herpesvirus (KSHV)-Encoded LANASIM-Associated Proteins in Hypoxia. mSystems 6(6): e01109-01121
• 216 Lui, H., et al. (2021). Fibroblastic differentiation of mesenchymal stem/stromal cells (MSCs) is enhanced by hypoxia in 3D cultures treated with bone morphogenetic protein 6 (BMP6) and growth and differentiation factor 5 (GDF5). Gene 788: 145662
• 217 Magdaleno, C., et al. (2021). Fibronectin assembly regulates lumen formation in breast acini. J Cell Biochem 122(5): 524-537.
• 218 Mamnoon, B., et al. (2021). Targeted polymeric nanoparticles for drug delivery to hypoxic, triple-negative breast tumors. ACS Appl Bio Mater 4(2): 1450-1460.
• 219 Manlapaz-Mann, A., et al. (2021). Effects of omega 3 polyunsaturated fatty acids, antioxidants, and/or non-steroidal inflammatory drugs in the brain of neonatal rats exposed to intermittent hypoxia. Int J Dev Neurosci 81(5): 448-460.
• 220 Manning, E. P., et al. (2021). Mechanisms of Hypoxia-Induced Pulmonary Arterial Stiffening in Mice Revealed by a Functional Genetics Assay of Structural, Functional, and Transcriptomic Data. Front Physiol 12: 726253.
• 221 Mantripragada, V. P., et al. (2021). Characterization of heterogeneous primary human cartilage-derived cell population using non-invasive live-cell phase-contrast time-lapse imaging. Cytotherapy 23(6): 488-499.
• 222 Mao, M., et al. (2021). Impact of intrauterine hypoxia on adolescent and adult cognitive function in rat offspring: sexual differences and the effects of spermidine intervention. Acta Pharmacol Sin 42(3): 361-369.
• 223 Marcouiller, F., et al. (2021). Metabolic responses to intermittent hypoxia are regulated by sex and estradiol in mice. Am J Physiol Endocrinol Metab 320(2): E316-E325.
• 224 Marcus, J. M., et al. (2021). PARP-1 activation leads to cytosolic accumulation of TDP-43 in neurons. Neurochem Int 148: 105077.
• 225 Marsh, K. G., et al. (2021). The peroxisomal enzyme, FAR1, is induced during ER stress in an ATF6-dependent manner in cardiac myocytes. Am J Physiol Heart Circ Physiol 320(5): H1813-H1821.
• 226 Martins, F. O., et al. (2021). Chronic Intermittent Hypoxia Induces Early-Stage Metabolic Dysfunction Independently of Adipose Tissue Deregulation. Antioxidants (Basel) 10(8): 1233.
• 227 Marulanda, K., et al. (2021). Intravenous Delivery of Lung-Targeted Nanofibers for Pulmonary Hypertension in Mice. Adv Healthc Mater 10(13): e2100302.
• 228 Mathias, M., et al. (2021). Neonatal Extracellular Superoxide Dismutase Knockout Mice Increase Total Superoxide Dismutase Activity and VEGF Expression after Chronic Hyperoxia. Antioxidants (Basel) 10(8): 1236.
• 229 Mathuber, M., et al. (2021). Development of a cobalt(iii)-based ponatinib prodrug system. Inorg Chem Front 8(10): 2468-2485.
• 230 Mavrodi, O. V., et al. (2021). Root Exudates Alter the Expression of Diverse Metabolic, Transport, Regulatory, and Stress Response Genes in Rhizosphere Pseudomonas. Front Microbiol 12: 651282.
• 231 Mezu-Ndubuisi, O. J., et al. (2021). Retinopathy of prematurity shows alterations in Vegfa164 isoform expression. Pediatr Res.
• 232 Miyauchi, K., et al. (2021). Renal interstitial fibroblasts coproduce erythropoietin and renin under anaemic conditions. EBioMedicine 64: 103209.
• 233 Monaco, G., et al. (2021). Mesenchymal Stromal Cell Differentiation for Generating Cartilage and Bone-Like Tissues In Vitro. Cells 10(8): 2165.
• 234 Moulton, M., et al. (2021). Neuronal ROS-Induced Glial Lipid Droplet Formation is Altered by Loss of Alzheimer’s Disease-Associated Genes. Available at SSRN 3811838
• 235 Mullin, N. K., et al. (2021). Patient derived stem cells for discovery and validation of novel pathogenic variants in inherited retinal disease. Prog Retin Eye Res 83: 100918.
• 236 Mulling, K., et al. (2021). Neutrophil dynamics, plasticity and function in acute neurodegeneration following neonatal hypoxia-ischemia. Brain Behav Immun 92: 234-244.
• 237 Mülling, K., et al. (2021). Neutrophil dynamics, plasticity and function in acute neurodegeneration following neonatal hypoxia–ischemia. Brain, behavior, and immunity 92: 234-244
• 238 Mustafa, G., et al. (2021). Antioxidants and/or fish oil reduce intermittent hypoxia-induced inflammation in the neonatal rat terminal ileum. Prostaglandins Other Lipid Mediat 155: 106565.
• 239 Nakahara, M., et al. (2021). The inflammatory role of dysregulated IRS2 in pulmonary vascular remodeling under hypoxic conditions. Am J Physiol Lung Cell Mol Physiol 321(2): L416-L428.
• 240 Namba, F. (2021). An experimental animal model of bronchopulmonary dysplasia: Secondary publication. Pediatr Int 63(5): 504-509.
• 241 Negi, V., et al. (2021). Computational repurposing of therapeutic small molecules from cancer to pulmonary hypertension. Sci Adv 7(43): eabh3794.
• 242 Nikolits, I., et al. (2021). Towards Physiologic Culture Approaches to Improve Standard Cultivation of Mesenchymal Stem Cells. Cells 10(4): 886.
• 243 Ninchoji, T., et al. (2021). eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin. eLife 10: e64944.
• 244 Nitzsche, A., et al. (2021). Paladin is a phosphoinositide phosphatase regulating endosomal VEGFR2 signalling and angiogenesis. EMBO Rep 22(2): e50218.
• 245 Noueihed, B., et al. (2021). Mesenchymal Stromal Cells Promote Retinal Vascular Repair by Modulating Sema3E and IL-17A in a Model of Ischemic Retinopathy. Front Cell Dev Biol 9: 630645.
• 246 Ntokou, A., et al. (2021). Macrophage-derived PDGF-B induces muscularization in murine and human pulmonary hypertension. JCI Insight 6(6).
• 247 Ordway, B., et al. (2021). Targeting of Evolutionarily Acquired Cancer Cell Phenotype by Exploiting pHi-Metabolic Vulnerabilities. Cancers 13(1): 64
• 248 Page, L. K., et al. (2021). Influence of Hypoxia on the Epithelial-Pathogen Interactions in the Lung: Implications for Respiratory Disease. Front Immunol 12(939): 653969.
• 249 Pan, J., et al. (2021). Alpinetin protects against hepatic ischemia/reperfusion injury in mice by inhibiting the NF-kappaB/MAPK signaling pathways. Int Immunopharmacol 95: 107527.
• 250 Papathanasiou, A. E., et al. (2021). Adipokines and Metabolic Regulators in Human and Experimental Pulmonary Arterial Hypertension. Int J Mol Sci 22(3): 1435.
• 251 Pascoaloti-Lima, J. C., et al. (2021). Sustained Hypoxia Reduces GABAergic Modulation on NTS Neurons Sending Projections to Ventral Medulla of Rats. Neuroscience 457: 1-11.
• 252 Paumann-Page, M., et al. (2021). Peroxidasin protein expression and enzymatic activity in metastatic melanoma cell lines are associated with invasive potential. Redox Biol 46: 102090.
• 253 Peng, L., et al. (2021). Extracellular Vesicles Derived from Intermittent Hypoxia-Treated Red Blood Cells Impair Endothelial Function Through Regulating eNOS Phosphorylation and ET-1 Expression. Cardiovasc Drugs Ther 35(5): 901-913.
• 254 Peng, S., et al. (2021). Hypoxia-degradable and long-circulating zwitterionic phosphorylcholine-based nanogel for enhanced tumor drug delivery. Acta Pharm Sin B 11(2): 560-571.
• 255 Penkala, I. J., et al. (2021). Age-dependent alveolar epithelial plasticity orchestrates lung homeostasis and regeneration. Cell Stem Cell 28(10): 1775-1789 e1775.
• 256 Perelli, R. M., et al. (2021). Environmental oxygen regulates astrocyte proliferation to guide angiogenesis during retinal development. Development 148(9): dev199418.
• 257 Piasecki, P., et al. (2021). A new in vitro model applied (90)Y microspheres to study the effects of low dose beta radiation on colorectal cancer cell line in various oxygenation conditions. Sci Rep 11(1): 4472.
• 258 Piasecki, P., et al. (2021). Initial experience with novel Embocure Plus microspheres for transarterial chemoembolization (TACE) of liver metastatic colorectal cancer tumours–a clinical and in vitro study. Polish Journal of Radiology 86: e136.
• 259 Porzionato, A., et al. (2021). Intratracheal administration of mesenchymal stem cell-derived extracellular vesicles reduces lung injuries in a chronic rat model of bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol 320(5): L688-L704.
• 260 Pressley, M., et al. (2021). Cycling hypoxia selects for constitutive HIF stabilization. Sci Rep 11(1): 5777.
• 261 Purandare, N., et al. (2021). Molecular mechanisms regulating lysophosphatidylcholine acyltransferase 1 (LPCAT1) in human pregnancy. Placenta 106: 40-48.
• 262 Qadri, A., et al. (2021). Ocular Versus Oral Propranolol for Prevention and/or Treatment of Oxygen-Induced Retinopathy in a Rat Model. J Ocul Pharmacol Ther 37(2): 112-130.
• 263 Rahman, S., et al. (2021). Inability of Low Oxygen Tension to Induce Chondrogenesis in Human Infrapatellar Fat Pad-Mesenchymal Stem Cells. Frontiers in Cell and Developmental Biology 9: 1780
• 264 Rajgarhia, A., et al. (2021). Extracellular Superoxide Dismutase (EC-SOD) Regulates Gene Methylation and Cardiac Fibrosis During Chronic Hypoxic Stress. Front Cardiovasc Med 8: 669975.
• 265 Rao, V. K. S., et al. (2021). Multiple roles for peptidylglycine alpha-amidating monooxygenase in the response to hypoxia. J Cell Physiol 236(11): 7745-7758.
• 266 Rashed, F. B., et al. (2021). Identification of proteins and cellular pathways targeted by 2-nitroimidazole hypoxic cytotoxins. Redox Biol 41: 101905.
• 267 Rehman, A. U., et al. (2021). Proline is a quencher of singlet oxygen and superoxide both in in vitro systems and isolated thylakoids. Physiologia Plantarum 172(1): 7-18.
• 268 Reis, M., et al. (2021). Mesenchymal Stromal Cell-Derived Extracellular Vesicles Restore Thymic Architecture and T Cell Function Disrupted by Neonatal Hyperoxia. Front Immunol 12: 640595.
• 269 Ribon-Demars, A., et al. (2021). Lung oxidative stress and transcriptional regulations induced by estradiol and intermittent hypoxia. Free Radic Biol Med 164: 119-129.
• 270 Rios-Colon, L., et al. (2021). Carnitine Palmitoyltransferase 1 Regulates Prostate Cancer Growth under Hypoxia. Cancers (Basel) 13(24): 6302.
• 271 Rodrigues, K. L., et al. (2021). Changes in the autonomic and respiratory patterns in mice submitted to short-term sustained hypoxia. Exp Physiol 106(3): 759-770.
• 272 Romanowicz, J., et al. (2021). Chronic perinatal hypoxia delays cardiac maturation in a mouse model for cyanotic congenital heart disease. Am J Physiol Heart Circ Physiol 320(5): H1873-H1886.
• 273 Safitri, E. and H. Purnobasuki (2021). Effectiveness of mesenchymal stem cells cultured under hypoxia to increase the fertility rate in rats (Rattus norvegicus). Vet World 14(11): 3056-3064.
• 274 Sakihama, H., et al. (2021). Carbon Monoxide Suppresses Neointima Formation in Transplant Arteriosclerosis by Inhibiting Vascular Progenitor Cell Differentiation. Arterioscler Thromb Vasc Biol 41(6): 1915-1927.
• 275 Samal, J. R. K., et al. (2021). Discrepancies on the Role of Oxygen Gradient and Culture Condition on Mesenchymal Stem Cell Fate. Adv Healthc Mater 10(6): e2002058.
• 276 Sanz-Rubio, D., et al. (2021). Cell-Selective Altered Cargo Properties of Extracellular Vesicles Following In Vitro Exposures to Intermittent Hypoxia. Int J Mol Sci 22(11): 5604.
• 277 Saralkar, P., et al. (2021). The Mitochondrial mitoNEET Ligand NL-1 Is Protective in a Murine Model of Transient Cerebral Ischemic Stroke. Pharm Res 38(5): 803-817.
• 278 Sathyanesan, A., et al. (2021). Disruption of neonatal Purkinje cell function underlies injury-related learning deficits. Proc Natl Acad Sci U S A 118(11).
• 279 Scaffa, A., et al. (2021). Single-cell transcriptomics reveals lasting changes in the lung cellular landscape into adulthood after neonatal hyperoxic exposure. Redox Biol 48: 102091.
• 280 Scharping, N. E., et al. (2021). Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion. Nat Immunol 22(2): 205-215.
• 281 Schauer, A., et al. (2021). Pharmacological Pre- and Postconditioning With Levosimendan Protect H9c2 Cardiomyoblasts From Anoxia/Reoxygenation-induced Cell Death via PI3K/Akt Signaling. J Cardiovasc Pharmacol 77(3): 378-385.
• 282 Scheuer, T., et al. (2021). Reduction of cortical parvalbumin-expressing GABAergic interneurons in a rodent hyperoxia model of preterm birth brain injury with deficits in social behavior and cognition. Development 148(20).
• 283 Schmidt, J., et al. (2021). Carbonic-anhydrase IX expression is increased in thyroid cancer tissue and represents a potential therapeutic target to eradicate thyroid tumor-initiating cells. Molecular and cellular endocrinology: 111382
• 284 Seeger, D. R., et al. (2021). Cyclooxygenase inhibition attenuates brain angiogenesis and independently decreases mouse survival under hypoxia. J Neurochem 158(2): 246-261.
• 285 Seitz, M., et al. (2021). Hypothermia modulates myeloid cell polarization in neonatal hypoxic-ischemic brain injury. J Neuroinflammation 18(1): 266.
• 286 Shah, D., et al. (2021). Retraction notice for: “miR-184 mediates hyperoxia-induced injury by targeting cell death and angiogenesis signalling pathways in the developing lung.” Dilip Shah, Karmyodh Sandhu, Pragnya Das, Zubair H. Aghai, Sture Andersson, Gloria Pryhuber and Vineet Bhandari. Eur Respir J 2020; in press. Eur Respir J 58(3).
• 287 Sharrock, A. V., et al. (2021). Engineering the Escherichia coli Nitroreductase NfsA to Create a Flexible Enzyme-Prodrug Activation System. Front Pharmacol 12: 701456.
• 288 She, D., et al. (2021). Hypoxia-degradable zwitterionic phosphorylcholine drug nanogel for enhanced drug delivery to glioblastoma. Chemical Engineering Journal 408: 127359.
• 289 Shen, W., et al. (2021). FTO overexpression inhibits apoptosis of hypoxia/reoxygenation-treated myocardial cells by regulating m6A modification of Mhrt. Mol Cell Biochem 476(5): 2171-2179.
• 290 Shimizu, T., et al. (2021). PERK inhibition attenuates vascular remodeling in pulmonary arterial hypertension caused by BMPR2 mutation. Sci Signal 14(667): eabb3616.
• 291 Shin, H.-W., et al. (2021). Urine 5-Eicosatetraenoic Acids as Diagnostic Markers for Obstructive Sleep Apnea. Antioxidants 10(8): 1242.
• 292 Silverstein, A. L. and W. J. Alilain (2021). Intermittent Hypoxia Induces Greater Functional Breathing Motor Recovery as a Fixed Rather Than Varied Duration Treatment after Cervical Spinal Cord Injury in Rats. Neurotrauma Reports 2(1): 343-353
• 293 Simões‐Pires, E. N., et al. (2021). Roles of glutamate receptors in a novel in vitro model of early, comorbid cerebrovascular, and Alzheimer’s diseases. Journal of neurochemistry 156(4): 539-552.
• 294 Simoes-Pires, E. N., et al. (2021). Roles of glutamate receptors in a novel in vitro model of early, comorbid cerebrovascular, and Alzheimer’s diseases. J Neurochem 156(4): 539-552.
• 295 Smith, T. L., et al. (2021). eNOS controls angiogenic sprouting and retinal neovascularization through the regulation of endothelial cell polarity. Cell Mol Life Sci 79(1): 37.
• 296 Song, H., et al. (2021). HIF-1alpha-Mediated Telomerase Reverse Transcriptase Activation Inducing Autophagy Through Mammalian Target of Rapamycin Promotes Papillary Thyroid Carcinoma Progression During Hypoxia Stress. Thyroid 31(2): 233-246.
• 297 Song, H., et al. (2021). HIF-1α-Mediated Telomerase Reverse Transcriptase Activation Inducing Autophagy Through Mammalian Target of Rapamycin Promotes Papillary Thyroid Carcinoma Progression During Hypoxia Stress. Thyroid 31(2): 233-246.
• 298 Soontarapornchai, K., et al. (2021). Pharmacodynamic Effects of Standard versus High Caffeine Doses in the Developing Brain of Neonatal Rats Exposed to Intermittent Hypoxia. Int J Mol Sci 22(7): 3473.
• 299 Sorenson, C. M., et al. (2021). Targeted Thrombospondin-1 Expression in Ocular Vascular Development and Neovascularization. Front Cell Dev Biol 9: 671989.
• 300 Spyropoulos, F., et al. (2021). Acetazolamide Improves Right Ventricular Function and Metabolic Gene Dysregulation in Experimental Pulmonary Arterial Hypertension. Front Cardiovasc Med 8: 662870.
• 301 Strutz, J., et al. (2021). Transient Hyperglycemia and Hypoxia Induce Memory Effects in AngiomiR Expression Profiles of Feto-Placental Endothelial Cells. Int J Mol Sci 22(24): 13378.
• 302 Sun, H., et al. (2021). Increased intracellular Cl(-) concentration in pulmonary arterial myocytes is associated with chronic hypoxic pulmonary hypertension. Am J Physiol Cell Physiol 321(2): C297-C307.
• 303 Sun, Y., et al. (2021). Intrauterine Hypoxia Changed the Colonization of the Gut Microbiota in Newborn Rats. Front Pediatr 9: 675022.
• 304 Szojka, A. R. A., et al. (2021). Engineered human meniscus’ matrix-forming phenotype is unaffected by low strain dynamic compression under hypoxic conditions. PLOS ONE 16(3): e0248292.
• 305 Szojka, A. R. A., et al. (2021). Mechano-Hypoxia Conditioning of Engineered Human Meniscus. Front Bioeng Biotechnol 9(792): 739438.
• 306 Szojka, A. R., et al. (2021). Human engineered meniscus transcriptome after short-term combined hypoxia and dynamic compression. J Tissue Eng 12: 2041731421990842.
• 307 Tandl, V., et al. (2021). Different regulation of IRE1α and eIF2α pathways by oxygen and insulin in ACH-3P trophoblast model. Reproduction 162(1): 1-10.
• 308 Tessonnier, T., et al. (2021). FLASH Dose Rate Helium Ion Beams: First In Vitro Investigations. Int J Radiat Oncol Biol Phys 111(4): 1011-1022.
• 309 Torosyan, R., et al. (2021). Hypoxic preconditioning protects against ischemic kidney injury through the IDO1/kynurenine pathway. Cell Rep 36(7): 109547.
• 310 Trivlidis, J., et al. (2021). HuR drives lung fibroblast differentiation but not metabolic reprogramming in response to TGF-beta and hypoxia. Respir Res 22(1): 323.
• 311 Tsai, M. J., et al. (2021). Minocycline exhibits synergism with conditioned medium of bone marrow mesenchymal stem cells against ischemic stroke. J Tissue Eng Regen Med 15(3): 279-292.
• 312 Tseng, W. C., et al. (2021). Hypoxic mesenchymal stem cells ameliorate acute kidney ischemia-reperfusion injury via enhancing renal tubular autophagy. Stem Cell Res Ther 12(1): 367.
• 313 Turlova, E., et al. (2021). TRPM7 Mediates Neuronal Cell Death Upstream of Calcium/Calmodulin-Dependent Protein Kinase II and Calcineurin Mechanism in Neonatal Hypoxic-Ischemic Brain Injury. Transl Stroke Res 12(1): 164-184.
• 314 Ulland, T. K., et al. (2021). Alzheimer’s Disease, Sleep Disordered Breathing, and Microglia: Puzzling out a Common Link. Cells 10(11): 2907
• 315 Vahatupa, M., et al. (2021). Selective Targeting and Tissue Penetration to the Retina by a Systemically Administered Vascular Homing Peptide in Oxygen Induced Retinopathy (OIR). Pharmaceutics 13(11).
• 316 Vainio, L., et al. (2021). GSK3beta Serine 389 Phosphorylation Modulates Cardiomyocyte Hypertrophy and Ischemic Injury. Int J Mol Sci 22(24): 13586.
• 317 Vang, A., et al. (2021). alpha7 Nicotinic acetylcholine receptor mediates right ventricular fibrosis and diastolic dysfunction in pulmonary hypertension. JCI Insight 6(12).
• 318 Vega-Tapia, F., et al. (2021). Specific arterio-venous transcriptomic and ncRNA-RNA-interactions in human umbilical endothelial cells: a meta-analysis. iScience: 102675
• 319 Veglia, F., et al. (2021). Analysis of classical neutrophils and polymorphonuclear myeloid-derived suppressor cells in cancer patients and tumor-bearing mice. J Exp Med 218(4).
• 320 Visniauskas, B., et al. (2021). Intermittent hypoxia changes the interaction of the kinin–VEGF system and impairs myocardial angiogenesis in the hypertrophic heart. Physiological Reports 9(9): e14863.
• 321 Wang, J. H., et al. (2021). Bulk Gene Expression Deconvolution Reveals Infiltration of M2 Macrophages in Retinal Neovascularization. Invest Ophthalmol Vis Sci 62(14): 22.
• 322 Wang, L., et al. (2021). Mice with a specific deficiency of Pfkfb3 in myeloid cells are protected from hypoxia-induced pulmonary hypertension. Br J Pharmacol 178(5): 1055-1072.
• 323 Wang, W., et al. (2021). Coordination of escape and spatial navigation circuits orchestrates versatile flight from threats. Neuron 109(11): 1848-1860 e1848.
• 324 Wang, Y. n., et al. (2021). Blocking the interaction between interleukin-17A and endoplasmic reticulum stress in macrophage attenuates retinal neovascularization in oxygen-induced retinopathy. Cell & bioscience 11(1): 1-17
• 325 Wang, Y., et al. (2021). Brown Adipose Tissue Activation Is Involved in Atherosclerosis of ApoE(-/-) Mice Induced by Chronic Intermittent Hypoxia. Front Cardiovasc Med 8: 751519.
• 326 Wang, Y., et al. (2021). Elevated reactivity of Apelin inhibited renal fibrosis induced by chronic intermittent hypoxia. Arch Biochem Biophys 711: 109021.
• 327 Wang, Y., et al. (2021). Mirabegron Ameliorated Atherosclerosis of ApoE(-/-) Mice in Chronic Intermittent Hypoxia but Not in Normoxia. Cardiovasc Drugs Ther.
• 328 Wang, Y., et al. (2021). Mirabegron Ameliorated Atherosclerosis of ApoE−/− Mice in Chronic Intermittent Hypoxia but Not in Normoxia. Cardiovascular Drugs and Therapy: 1-11
• 329 Wang, Y., et al. (2021). PTEN protects kidney against acute kidney injury by alleviating apoptosis and promoting autophagy via regulating HIF1-alpha and mTOR through PI3K/Akt pathway. Exp Cell Res 406(1): 112729.
• 330 Wendt, T. S., et al. (2021). Ozanimod, an S1PR1 ligand, attenuates hypoxia plus glucose deprivation-induced autophagic flux and phenotypic switching in human brain VSM cells. Am J Physiol Cell Physiol 320(6): C1055-C1073.
• 331 Wiacek, M. P., et al. (2021). Long-Term Effects of Adjuvant Intravitreal Treatment with Autologous Bone Marrow-Derived Lineage-Negative Cells in Retinitis Pigmentosa. Stem Cells Int 2021: 6631921.
• 332 Willis, G. R., et al. (2021). Extracellular Vesicles Protect the Neonatal Lung from Hyperoxic Injury through the Epigenetic and Transcriptomic Reprogramming of Myeloid Cells. Am J Respir Crit Care Med 204(12): 1418-1432.
• 333 Wu, G., et al. (2021). Short-term exposure to intermittent hypoxia leads to changes in gene expression seen in chronic pulmonary disease. eLife 10: e63003.
• 334 Wu, X., et al. (2021). NLRP3 Deficiency Protects Against Intermittent Hypoxia-Induced Neuroinflammation and Mitochondrial ROS by Promoting the PINK1-Parkin Pathway of Mitophagy in a Murine Model of Sleep Apnea. Front Immunol 12: 628168.
• 335 Wu, Z., et al. (2021). OMA1 reprograms metabolism under hypoxia to promote colorectal cancer development. EMBO Rep 22(1): e50827.
• 336 Wyrwoll, C. S., et al. (2021). Long-term exposure of mice to 890 ppm atmospheric CO2 alters growth trajectories and elicits hyperactive behaviours in young adulthood. J Physiol.
• 337 Xiong, M., et al. (2021). Mouse model of experimental pulmonary hypertension: Lung angiogram and right heart catheterization. Pulm Circ 11(4): 20458940211041512.
• 338 Xu, L., et al. (2021). Suppression of CHOP Reduces Neuronal Apoptosis and Rescues Cognitive Impairment Induced by Intermittent Hypoxia by Inhibiting Bax and Bak Activation. Neural Plast 2021: 4090441.
• 339 Xu, M., et al. (2021). DJ-1 Deficiency in Hepatocytes Improves Liver Ischemia-Reperfusion Injury by Enhancing Mitophagy. Cell Mol Gastroenterol Hepatol 12(2): 567-584.
• 340 Xu, S., et al. (2021). The role of RNA m(6)A methylation in the regulation of postnatal hypoxia-induced pulmonary hypertension. Respir Res 22(1): 121.
• 341 Xu, Y., et al. (2021). Inhibiting miR-205 Alleviates Cardiac Ischemia/Reperfusion Injury by Regulating Oxidative Stress, Mitochondrial Function, and Apoptosis. Oxid Med Cell Longev 2021: 9986506.
• 342 Xu, Y., et al. (2021). Mild Hypoxia Enhances the Expression of HIF and VEGF and Triggers the Response to Injury in Rat Kidneys. Front Physiol 12: 690496.
• 343 Yan, Y. R., et al. (2021). Chronic intermittent hypoxia-induced mitochondrial dysfunction mediates endothelial injury via the TXNIP/NLRP3/IL-1beta signaling pathway. Free Radic Biol Med 165: 401-410.
• 344 Yang, J., et al. (2021). Sevoflurane preconditioning promotes mesenchymal stem cells to relieve myocardial ischemia/reperfusion injury via TRPC6-induced angiogenesis. Stem Cell Res Ther 12(1): 584.
• 345 Yang, Y. Y., et al. (2021). Angiopoietin-like proteins 8 knockout reduces intermittent hypoxia-induced vascular remodeling in a murine model of obstructive sleep apnea. Biochem Pharmacol 186: 114502.
• 346 Zaitoun, I. S., et al. (2021). Hypoxic-ischemic injury causes functional and structural neurovascular degeneration in the juvenile mouse retina. Sci Rep 11(1): 12670.
• 347 Zarkada, G., et al. (2021). Specialized endothelial tip cells guide neuroretina vascularization and blood-retina-barrier formation. Dev Cell 56(15): 2237-2251 e2236.
• 348 Zhang, J., et al. (2021). Transforming Growth Factor-beta1 Enhances Mesenchymal Characteristics of Buffalo (Bubalus bubalis) Bone Marrow-Derived Mesenchymal Stem Cells. Cell Reprogram 23(2): 127-138.
• 349 Zhang, L., et al. (2021). Endogenous sulfur dioxide is a novel inhibitor of hypoxia-induced mast cell degranulation. Journal of Advanced Research 29: 55-65
• 350 Zhang, L.-j., et al. (2021). Lipoxin A4 Attenuates the Lung Ischemia Reperfusion Injury in Rats After Lung Transplantation.
• 351 Zhang, X., et al. (2021). Visualizing and evaluating mitochondrial cysteine via near-infrared fluorescence imaging in cells, tissues and in vivo under hypoxia/reperfusion stress. J Hazard Mater 419: 126476.
• 352 Zhao, J., et al. (2021). Zwitterionic Block Copolymer Prodrug Micelles for pH Responsive Drug Delivery and Hypoxia-Specific Chemotherapy. Mol Pharm.
• 353 Zhao, L., et al. (2021). CB1 receptor antagonist rimonabant protects against chronic intermittent hypoxia-induced renal injury in rats. BMC Nephrol 22(1): 153.
• 354 Zhao, M., et al. (2021). MicroRNA153 attenuates hypoxiainduced excessive proliferation and migration of pulmonary arterial smooth muscle cells by targeting ROCK1 and NFATc3. Mol Med Rep 23(3).
• 355 Zhao, Y. and X. Lin (2021). A PAS Protein Directs Metabolic Reprogramming during Cryptococcal Adaptation to Hypoxia. mBio 12(2).
• 356 Zhao, Y., et al. (2021). Non-enzymatic glucose biofuel cells based on highly porous PtxNi1-x nanoalloys. Journal of Materials Science 56(23): 13066-13082.
• 357 Zhao, Y., et al. (2021). The effects of short time hyperoxia on glutamate concentration and glutamate transporters expressions in brain of neonatal rats. Neurosci Lett 758: 136013.
• 358 Zhao, Z., et al. (2021). MicroRNA let-7f alleviates vascular endothelial cell dysfunction via targeting HMGA2 under oxygen-glucose deprivation and reoxygenation. Brain Res 1772: 147662.
• 359 Zhen, X., et al. (2021). Combined intermittent and sustained hypoxia is a novel and deleterious cardio-metabolic phenotype. Sleep.
• 360 Zhou, D., et al. (2021). Microbiota Modulates Cardiac Transcriptional Responses to Intermittent Hypoxia and Hypercapnia. Front Physiol 12: 680275.
• 361 Zhou, H., et al. (2021). The mineral dust-induced gene, mdig, regulates angiogenesis and lymphangiogenesis in lung adenocarcinoma by modulating the expression of VEGF-A/C/D via EGFR and HIF-1α signaling. Oncology reports 45(5): 1-13
• 362 Zhou, J., et al. (2021). A rapid juvenile murine model of nonalcoholic steatohepatitis (NASH): Chronic intermittent hypoxia exacerbates Western diet-induced NASH. Life Sci 276: 119403.
• 363 Zhou, T., et al. (2021). IL-17 signaling induces iNOS+ microglia activation in retinal vascular diseases. Glia 69(11): 2644-2657.
• 364 Zhou, W., et al. (2021). Flooding represses soybean seed germination by mediating anaerobic respiration, glycometabolism and phytohormones biosynthesis. Environmental and Experimental Botany 188: 104491.
• 365 Abu-El-Rub, E., et al. (2020). Hypoxia-induced increase in Sug1 leads to poor post-transplantation survival of allogeneic mesenchymal stem cells. FASEB J 34(9): 12860-12876.
• 366 Abu-El-Rub, E., et al. (2020). Hypoxia-induced shift in the phenotype of proteasome from 26S toward immunoproteasome triggers loss of immunoprivilege of mesenchymal stem cells. Cell Death Dis 11(6): 419.
• 367 Ahmed, F., et al. (2020). Meprin-beta activity modulates the beta-catalytic subunit of protein kinase A in ischemia-reperfusion-induced acute kidney injury. Am J Physiol Renal Physiol 318(5): F1147-F1159.
• 368 Alleboina, S., et al. (2020). Inhibition of protein kinase C beta phosphorylation activates nuclear factor-kappa B and improves postischemic recovery in type 1 diabetes. Exp Biol Med (Maywood) 245(9): 785-796.
• 369 Amgalan, D., et al. (2020). A small-molecule allosteric inhibitor of BAX protects against doxorubicin-induced cardiomyopathy. Nat Cancer 1(3): 315-328.
• 370 Aravamuthan, B. R., et al. (2020). Sex may influence motor phenotype in a novel rodent model of cerebral palsy. Neurobiol Dis 134: 104711.
• 371 Arita, M., et al. (2020). Licochalcone A Inhibits BDNF and TrkB Gene Expression and Hypoxic Growth of Human Tumor Cell Lines. Int J Mol Sci 21(2): 506.
• 372 Ashley, S. L., et al. (2020). Lung and gut microbiota are altered by hyperoxia and contribute to oxygen-induced lung injury in mice. Sci Transl Med 12(556): eaau9959.
• 373 Bachmann, J., et al. (2020). Ischemia-Like Stress Conditions Stimulate Trophic Activities of Adipose-Derived Stromal/Stem Cells. Cells 9(9).
• 374 Badran, M., et al. (2020). Fecal microbiota transplantation from mice exposed to chronic intermittent hypoxia elicits sleep disturbances in naive mice. Exp Neurol 334: 113439.
• 375 Bagati, A., et al. (2020). Novel combination therapy for melanoma induces apoptosis via a gap junction positive feedback mechanism. Oncotarget 11(37): 3443-3458.
• 376 Barbosa, D. M., et al. (2020). Rhein, a novel Histone Deacetylase (HDAC) inhibitor with antifibrotic potency in human myocardial fibrosis. Sci Rep 10(1): 4888.
• 377 Bats, M. L., et al. (2020). Therapies targeting Frizzled-7/beta-catenin pathway prevent the development of pathological angiogenesis in an ischemic retinopathy model. FASEB J 34(1): 1288-1303.
• 378 Beer, Y., et al. (2020). 3β‐Diol Attenuates COX‐2 Levels in a Neonatal In‐Vivo and In‐Vitro Ischemic Injury Rodent and Human Model. The FASEB Journal 34(S1): 1-1.
• 379 Beharry, K. D., et al. (2020). Combination Antioxidant/NSAID Therapies and Oral/Topical Ocular Delivery Modes for Prevention of Oxygen-Induced Retinopathy in a Rat Model. Nutrients 12(7).
• 380Bennett, A. D. and C. F. Rakocinski (2020). Respiration by the Opportunistic Spionid Polychaete Streblospio gynobranchiata during Adjustment to and Recovery from Moderate Hypoxia. Diversity 12(2): 73
• 381 Bermudez, D., et al. (2020). Increased hypoxic proliferative response and gene expression in erythroid progenitor cells of Andean highlanders with chronic mountain sickness. Am J Physiol Regul Integr Comp Physiol 318(1): R49-R56.
• 382 Bharat, A., et al. (2020). High CO2 Levels Impair Lung Wound Healing. Am J Respir Cell Mol Biol 63(2): 244-254.
• 383 Bhedi, C. D., et al. (2020). Glycolysis regulated transglutaminase 2 activation in cardiopulmonary fibrogenic remodeling. FASEB J 34(1): 930-944.
• 384 Bikou, O., et al. (2020). Induction and Characterization of Pulmonary Hypertension in Mice using the Hypoxia/SU5416 Model. J Vis Exp(160).
• 385 Bittencourt-Silva, P. G., et al. (2020). Postnatal intermittent hypoxia enhances phrenic and reduces vagal upper airway motor activities in rats by epigenetic mechanisms. Exp Physiol 105(1): 148-159.
• 386 Brackley, A. D., et al. (2020). Intermittent hypercapnic hypoxia induces respiratory hypersensitivity to fentanyl accompanied by tonic respiratory depression by endogenous opioids. J Physiol 598(15): 3239-3257.
• 387 Bretz, C. A., et al. (2020). Erythropoietin Receptor Signaling Supports Retinal Function after Vascular Injury. Am J Pathol 190(3): 630-641.
• 388 Bretz, C. A., et al. (2020). Signaling Through the Erythropoietin Receptor Affects Angiogenesis in Retinovascular Disease. Invest Ophthalmol Vis Sci 61(10): 23.
• 389 Casalino-Matsuda, S. M., et al. (2020). Hypercapnia Suppresses Macrophage Antiviral Activity and Increases Mortality of Influenza A Infection via Akt1. J Immunol 205(2): 489-501.
• 390 Cavallo, D., et al. (2020). Neuroprotective effects of mGluR5 activation through the PI3K/Akt pathway and the molecular switch of AMPA receptors. Neuropharmacology 162: 107810.
• 391 Ceco, E., et al. (2020). Elevated CO2 Levels Delay Skeletal Muscle Repair by Increasing Fatty Acid Oxidation. Front Physiol 11: 630910.
• 392 Chao, C. M., et al. (2020). Failure to Down-Regulate miR-154 Expression in Early Postnatal Mouse Lung Epithelium Suppresses Alveologenesis, with Changes in Tgf-beta Signaling Similar to those Induced by Exposure to Hyperoxia. Cells 9(4).
• 393 Chavali, M., et al. (2020). Wnt-Dependent Oligodendroglial-Endothelial Interactions Regulate White Matter Vascularization and Attenuate Injury. Neuron 108(6): 1130-1145 e1135.
• 394 Chen, H., et al. (2020). Ghrelin suppresses migration of macrophages via inhibition of ROCK2 under chronic intermittent hypoxia. J Int Med Res 48(6): 300060520926065.
• 395 Chen, H., et al. (2020). NLRP12 collaborates with NLRP3 and NLRC4 to promote pyroptosis inducing ganglion cell death of acute glaucoma. Mol Neurodegener 15(1): 26.
• 396 Chen, X., et al. (2020). Pharmacokinetics of Inter-Alpha Inhibitor Proteins and Effects on Hemostasis After Hypoxic-Ischemic Brain Injury in Neonatal Rats. Curr Pharm Des 26(32): 3997-4006.
• 397 Cho, H., et al. (2020). iPSC-derived endothelial cell response to hypoxia via SDF1a/CXCR4 axis facilitates incorporation to revascularize ischemic retina. JCI Insight 5(6).
• 398 Clapper, E., et al. (2020). The regulation of bcr-abl in hypoxia is through the mTOR pathway. Leukemia & Lymphoma: 1-12
• 399 Coelho, N. R., et al. (2020). First evidence of aryl hydrocarbon receptor as a druggable target in hypertension induced by chronic intermittent hypoxia. Pharmacol Res 159: 104869.
• 400 Cohen, E. B., et al. (2020). Metabolic pathway alterations in microvascular endothelial cells in response to hypoxia. PLOS ONE 15(7): e0232072.
• 401 Coucha, M., et al. (2020). Increased Ephrin-B2 expression in pericytes contributes to retinal vascular death in rodents. Vascul Pharmacol 131: 106761.
• 402 Coy, R., et al. (2020). Combining in silico and in vitro models to inform cell seeding strategies in tissue engineering. J R Soc Interface 17(164): 20190801.
• 403 Cubillos-Zapata, C., et al. (2020). Differential effect of intermittent hypoxia and sleep fragmentation on PD-1/PD-L1 upregulation. Sleep 43(5).
• 404 Cubillos-Zapata, C., et al. (2020). Proangiogenic factor midkine is increased in melanoma patients with sleep apnea and induces tumor cell proliferation. FASEB J 34(12): 16179-16190.
• 405 Dalal, S., et al. (2020). Exogenous ubiquitin attenuates hypoxia/reoxygenation-induced cardiac myocyte apoptosis via the involvement of CXCR4 and modulation of mitochondrial homeostasis. Biochem Cell Biol 98(4): 492-501.
• 406 Dantzler, H. A. and D. D. Kline (2020). Exaggerated potassium current reduction by oxytocin in visceral sensory neurons following chronic intermittent hypoxia. Auton Neurosci 229: 102735.
• 407 Das, P., et al. (2020). Small Molecule Inhibitor Adjuvant Surfactant Therapy Attenuates Ventilator- and Hyperoxia-Induced Lung Injury in Preterm Rabbits. Front Physiol 11: 266.
• 408 Deep, G., et al. (2020). Exosomes secreted by prostate cancer cells under hypoxia promote matrix metalloproteinases activity at pre-metastatic niches. Mol Carcinog 59(3): 323-332.
• 409 Deng, Y., et al. (2020). TLR2 antagonism attenuates the hippocampal neuronal damage in a murine model of sleep apnea via inhibiting neuroinflammation and oxidative stress. Sleep Breath 24(4): 1613-1621.
• 410 Desjarlais, M., et al. (2020). MicroRNA-96 Promotes Vascular Repair in Oxygen-Induced Retinopathy-A Novel Uncovered Vasoprotective Function. Front Pharmacol 11: 13.
• 411 Devarasetty, M., et al. (2020). Simulating the human colorectal cancer microenvironment in 3D tumor-stroma co-cultures in vitro and in vivo. Sci Rep 10(1): 9832.
• 412 Dewan, M. V., et al. (2020). Repetitive Erythropoietin Treatment Improves Long-Term Neurocognitive Outcome by Attenuating Hyperoxia-Induced Hypomyelination in the Developing Brain. Front Neurol 11: 804.
• 413 Dewitte, A., et al. (2020). CD154 Induces Interleukin-6 Secretion by Kidney Tubular Epithelial Cells under Hypoxic Conditions: Inhibition by Chloroquine. Mediators Inflamm 2020: 6357046.
• 414 Diaz-Garcia, E., et al. (2020). SMAD4 Overexpression in Patients with Sleep Apnoea May Be Associated with Cardiometabolic Comorbidities. J Clin Med 9(8).
• 415 Donato, C., et al. (2020). Hypoxia Triggers the Intravasation of Clustered Circulating Tumor Cells. Cell Rep 32(10): 108105.
• 416 Donnelly, W. T., et al. (2020). Prenatal intermittent hypoxia sensitizes the laryngeal chemoreflex, blocks serotoninergic shortening of the reflex, and reduces 5-HT3 receptor binding in the NTS in anesthetized rat pups. Exp Neurol 326: 113166.
• 417 Du, W., et al. (2020). Ephrin-A5 Is Involved in Retinal Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy. Biomed Res Int 2020: 7161027.
• 418 Du, Y., et al. (2020). miRNA-Mediated Suppression of a Cardioprotective Cardiokine as a Novel Mechanism Exacerbating Post-MI Remodeling by Sleep Breathing Disorders. Circ Res 126(2): 212-228.
• 419 Dunigan-Russell, K., et al. (2020). Club Cell Heme Oxygenase-1 Deletion: Effects in Hyperoxia-Exposed Adult Mice. Oxid Med Cell Longev 2020: 2908271.
• 420 Dutta, S., et al. (2020). Hypoxia-induced small extracellular vesicle proteins regulate proinflammatory cytokines and systemic blood pressure in pregnant rats. Clin Sci (Lond) 134(6): 593-607.
• 421 Dzah, C. S., et al. (2020). Ultrasound-, subcritical water- and ultrasound assisted subcritical water-derived Tartary buckwheat polyphenols show superior antioxidant activity and cytotoxicity in human liver carcinoma cells. Food Res Int 137: 109598.
• 422 El-Tohamy, R., et al. (2020). Myoglobin variants are expressed in human glioblastoma cellshypoxia effect? Oncol Rep 43(3): 975-985.
• 423 Endesfelder, S., et al. (2020). Prevention of Oxygen-Induced Inflammatory Lung Injury by Caffeine in Neonatal Rats. Oxid Med Cell Longev 2020: 3840124.
• 424 Faes, C., et al. (2020). Effects of hypoxia-reoxygenation stimuli on renal redox status and nuclear factor erythroid 2-related factor 2 pathway in sickle cell SAD mice. Exp Physiol 105(2): 357-369.
• 425 Fan, M., et al. (2020). Endothelial cell HSPA12B and yes-associated protein cooperatively regulate angiogenesis following myocardial infarction. JCI Insight 5(18).
• 426 Feddersen, S., et al. (2020). Impact of litter size on survival, growth and lung alveolarization of newborn mouse pups. Ann Anat 232: 151579.
• 427 Flor, K. C., et al. (2020). Inhibitory control of active expiration by the Botzinger complex in rats. J Physiol 598(21): 4969-4994.
• 428 Forbes, T. A., et al. (2020). Environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery. Nat Commun 11(1): 964.
• 429 Forstner, D., et al. (2020). Platelet-derived factors impair placental chorionic gonadotropin beta-subunit synthesis. J Mol Med (Berl) 98(2): 193-207.
• 430 Foster, A. J., et al. (2020). Applications of a novel radiotelemetry method for the measurement of intrathoracic pressures and physiological rhythms in freely behaving mice. J Appl Physiol (1985) 129(4): 992-1005.
• 431 Fu, H., et al. (2020). Interleukin 35 Delays Hindlimb Ischemia-Induced Angiogenesis Through Regulating ROS-Extracellular Matrix but Spares Later Regenerative Angiogenesis. Front Immunol 11(2662): 595813.
• 432 Fukushima, Y., et al. (2020). RhoJ integrates attractive and repulsive cues in directional migration of endothelial cells. EMBO J 39(12): e102930.
• 433 Gaborit, B., et al. (2020). Glucagon-like Peptide 1 Receptor Agonists, Diabetic Retinopathy and Angiogenesis: The AngioSafe Type 2 Diabetes Study. J Clin Endocrinol Metab 105(4).
• 434 Gandham, S., et al. (2020). Striatal cholinergic interneuron numbers are increased in a rodent model of dystonic cerebral palsy. Neurobiol Dis 144: 105045.
• 435 Gao, B., et al. (2020). Brain Endothelial Cell-Derived Exosomes Induce Neuroplasticity in Rats with Ischemia/Reperfusion Injury. ACS Chem Neurosci 11(15): 2201-2213.
• 436 Ge, H., et al. (2020). Ambroxol Upregulates Glucocerebrosidase Expression to Promote Neural Stem Cells Differentiation Into Neurons Through Wnt/beta-Catenin Pathway After Ischemic Stroke. Front Mol Neurosci 13: 596039.
• 437 Gerace, E., et al. (2020). Differential mechanisms of tolerance induced by NMDA and 3,5-dihydroxyphenylglycine (DHPG) preconditioning. J Neurochem 155(6): 638-649.
• 438 Gerace, E., et al. (2020). Tolerance Induced by (S)-3,5-Dihydroxyphenylglycine Postconditioning is Mediated by the PI3K/Akt/GSK3beta Signalling Pathway in an In Vitro Model of Cerebral Ischemia. Neuroscience 433: 221-229.
• 439 Gidlof, O., et al. (2020). Inhibition of the long non-coding RNA NEAT1 protects cardiomyocytes from hypoxia in vitro via decreased pri-miRNA processing. Cell Death Dis 11(8): 677.
• 440 Gomez-Puerto, M. C., et al. (2020). MnTBAP Reverses Pulmonary Vascular Remodeling and Improves Cardiac Function in Experimentally Induced Pulmonary Arterial Hypertension. Int J Mol Sci 21(11).
• 441 Gong, J., et al. (2020). Endothelial to mesenchymal transition during neonatal hyperoxia-induced pulmonary hypertension. J Pathol 252(4): 411-422.
• 442 Gong, L. J., et al. (2020). Pinocembrin ameliorates intermittent hypoxia-induced neuroinflammation through BNIP3-dependent mitophagy in a murine model of sleep apnea. J Neuroinflammation 17(1): 337.
• 443 Gore, A., et al. (2020). The nitric oxide donor, (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl)amino]diazen-1-ium-1,2-diolate (DETA-NONOate/D-NO), increases survival by attenuating hyperoxia-compromised innate immunity in bacterial clearance in a mouse model of ventilator-associated pneumonia. Biochem Pharmacol 176: 113817.
• 444 Grannonico, M., et al. (2020). DF3016A induces increased BDNF transcription in ischemic neuroinflammation injury. Brain Res 1748: 147057.
• 445 Grant, Z. L., et al. (2020). Blocking endothelial apoptosis revascularizes the retina in a model of ischemic retinopathy. J Clin Invest 130(8): 4235-4251.
• 446 Guo, W. Z., et al. (2020). Six-Transmembrane Epithelial Antigen of the Prostate 3 Deficiency in Hepatocytes Protects the Liver Against Ischemia-Reperfusion Injury by Suppressing Transforming Growth Factor-beta-Activated Kinase 1. Hepatology 71(3): 1037-1054.
• 447 Guzel, S., et al. (2020). Bumetanide Suppression of Angiogenesis in a Rat Model of Oxygen-Induced Retinopathy. Int J Mol Sci 21(3).
• 448 Ha, J. H., et al. (2020). Effects of long term normobaric hyperoxia exposure on lipopolysaccharide-induced lung injury. Exp Lung Res 46(1-2): 44-52.
• 449 Hait, N. C., et al. (2020). Regulation of hypoxia-inducible factor functions in the nucleus by sphingosine-1-phosphate. FASEB J 34(3): 4293-4310.
• 450 Halder, S. K. and R. Milner (2020). Chronic mild hypoxia accelerates recovery from preexisting EAE by enhancing vascular integrity and apoptosis of infiltrated monocytes. Proc Natl Acad Sci U S A 117(20): 11126-11135.
• 451 Halder, S. K. and R. Milner (2020). Mild hypoxia triggers transient blood-brain barrier disruption: a fundamental protective role for microglia. Acta Neuropathol Commun 8(1): 175.
• 452 Hallal, R., et al. (2020). Acriflavine targets oncogenic STAT5 signaling in myeloid leukemia cells. J Cell Mol Med 24(17): 10052-10062.
• 453 Harman, J. C., et al. (2020). Intermittent Hypoxia Promotes Functional Neuroprotection from Retinal Ischemia in Untreated First-Generation Offspring: Proteomic Mechanistic Insights. Invest Ophthalmol Vis Sci 61(11): 15.
• 454 Hilchey, S. P., et al. (2020). Cyclosporine a directly affects human and mouse b cell migration in vitro by disrupting a hIF-1 alphadependent, o2 sensing, molecular switch. BMC Immunol 21(1): 13.
• 455 Hill, N. C., et al. (2020). Life cycle of a cyanobacterial carboxysome. Sci Adv 6(19): eaba1269.
• 456 Hoch, D., et al. (2020). Maternal Obesity Alters Placental Cell Cycle Regulators in the First Trimester of Human Pregnancy: New Insights for BRCA1. Int J Mol Sci 21(2).
• 457 Hsieh, T. E., et al. (2020). Optimizing an Injectable Composite Oxygen-Generating System for Relieving Tissue Hypoxia. Front Bioeng Biotechnol 8: 511.
• 458 Huang, T., et al. (2020). Circular RNA YAP1 acts as the sponge of microRNA-21-5p to secure HK-2 cells from ischaemia/reperfusion-induced injury. J Cell Mol Med 24(8): 4707-4715.
• 459 Ishak Gabra, M. B., et al. (2020). Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth. Nat Commun 11(1): 3326.
• 460 Ivashkiv, L. B. (2020). The hypoxia-lactate axis tempers inflammation. Nat Rev Immunol 20(2): 85-86.
• 461 Jain, I. H., et al. (2020). Genetic Screen for Cell Fitness in High or Low Oxygen Highlights Mitochondrial and Lipid Metabolism. Cell 181(3): 716-727 e711.
• 462 Jewer, M., et al. (2020). Translational control of breast cancer plasticity. Nat Commun 11(1): 2498.
• 463 Jiangqiao, Z., et al. (2020). Ubiquitin-Specific Peptidase 10 Protects Against Hepatic Ischaemic/Reperfusion Injury via TAK1 Signalling. Front Immunol 11: 506275.
• 464 Joseph, V., et al. (2020). Progesterone decreases apnoea and reduces oxidative stress induced by chronic intermittent hypoxia in ovariectomized female rats. Exp Physiol 105(6): 1025-1034.
• 465 Junejo, R. T., et al. (2020). Prostaglandin contribution to postexercise hyperemia is dependent on tissue oxygenation during rhythmic and isometric contractions. Physiol Rep 8(12): e14471.
• 466 Jung, D. H., et al. (2020). Electroacupuncture on the Scalp over the Motor Cortex Ameliorates Behavioral Deficits Following Neonatal Hypoxia-Ischemia in Rats via the Activation of Neural Stem Cells. Life (Basel) 10(10): 240.
• 467 Kaiser, S., et al. (2020). Carbon monoxide controls microglial erythrophagocytosis by regulating CD36 surface expression to reduce the severity of hemorrhagic injury. Glia 68(11): 2427-2445.
• 468 Kaminski, N., et al. (2020). Mesenchymal Stromal Cell-Derived Extracellular Vesicles Reduce Neuroinflammation, Promote Neural Cell Proliferation and Improve Oligodendrocyte Maturation in Neonatal Hypoxic-Ischemic Brain Injury. Front Cell Neurosci 14: 601176.
• 469 Kang, H. H., et al. (2020). The Effects of Chronic Intermittent Hypoxia in Bleomycin-induced lung injury on Pulmonary Fibrosis via Regulating the NF-κB/Nrf2 Signaling Pathway. Tuberculosis and Respiratory Diseases
• 470 Kang, H. S., et al. (2020). Intermittent hypoxia exacerbates tumor progression in a mouse model of lung cancer. Sci Rep 10(1): 1854.
• 471 Kang, Y., et al. (2020). Sulforaphane prevents right ventricular injury and reduces pulmonary vascular remodeling in pulmonary arterial hypertension. Am J Physiol Heart Circ Physiol 318(4): H853-H866.
• 472 Khalyfa, A., et al. (2020). Transcriptomic Changes of Murine Visceral Fat Exposed to Intermittent Hypoxia at Single Cell Resolution. Int J Mol Sci 22(1).
• 473 Kim, J., et al. (2020). Inhibition of hypoxia-inducible factor 1alpha accumulation by glyceryl trinitrate and cyclic guanosine monophosphate. Biosci Rep 40(1).
• 474 Kim, S. W., et al. (2020). Effects of chronic intermittent hypoxia caused by obstructive sleep apnea on lipopolysaccharide-induced acute lung injury. Exp Lung Res 46(9): 341-351.
• 475 Kinoshita, S., et al. (2020). Real-time Monitoring of Hypoxic-Ischemic Brain Damage in Neonatal Rats Using Diffuse Light Reflectance Spectroscopy. Reprod Sci 27(1): 172-181.
• 476 Klomp, J., et al. (2020). Comprehensive transcriptomic profiling reveals SOX7 as an early regulator of angiogenesis in hypoxic human endothelial cells. Journal of Biological Chemistry: jbc. RA119. 011822
• 477 Koehler, J., et al. (2020). Differential Expression of miRNAs in Hypoxia (“HypoxamiRs”) in Three Canine High-Grade Glioma Cell Lines. Front Vet Sci 7: 104.
• 478 Kolle, S. T., et al. (2020). Ex vivo-expanded autologous adipose tissue-derived stromal cells ensure enhanced fat graft retention in breast augmentation: A randomized controlled clinical trial. Stem Cells Transl Med 9(11): 1277-1286.
• 479 Kolosowska, N., et al. (2020). Intracerebral overexpression of miR-669c is protective in mouse ischemic stroke model by targeting MyD88 and inducing alternative microglial/macrophage activation. J Neuroinflammation 17(1): 194.
• 480 Korponay, T. C., et al. (2020). High CO2 Downregulates Skeletal Muscle Protein Anabolism via AMP-activated Protein Kinase alpha2-mediated Depressed Ribosomal Biogenesis. Am J Respir Cell Mol Biol 62(1): 74-86.
• 481 Kryvenko, V., et al. (2020). Hypercapnia Impairs Na,K-ATPase Function by Inducing Endoplasmic Reticulum Retention of the beta-Subunit of the Enzyme in Alveolar Epithelial Cells. Int J Mol Sci 21(4).
• 482 Kumar, R., et al. (2020). Interstitial macrophage-derived thrombospondin-1 contributes to hypoxia-induced pulmonary hypertension. Cardiovasc Res 116(12): 2021-2030.
• 483 Kumar, V. H. S., et al. (2020). Short-term perinatal oxygen exposure may impair lung development in adult mice. Biol Res 53(1): 51.
• 484 Lafleur, M. A., et al. (2020). MRGPRX2 activation as a rapid, high-throughput mechanistic-based approach for detecting peptide-mediated human mast cell degranulation liabilities. J Immunotoxicol 17(1): 110-121.
• 485 Lech, W., et al. (2020). Biomimetic microenvironmental preconditioning enhance neuroprotective properties of human mesenchymal stem cells derived from Wharton’s Jelly (WJ-MSCs). Sci Rep 10(1): 16946.
• 486 Lei, Y., et al. (2020). O-GlcNAcylation of PFKFB3 is required for tumor cell proliferation under hypoxia. Oncogenesis 9(2): 21.
• 487 Li, C., et al. (2020). Expression of BACE1 in the Rat Carotid Body. Front Physiol 11: 505.
• 488 Li, C., et al. (2020). Functional glutamate transporters are expressed in the carotid chemoreceptor. Respir Res 21(1): 208.
• 489 Li, J., et al. (2020). Blocking GSDMD processing in innate immune cells but not in hepatocytes protects hepatic ischemia-reperfusion injury. Cell Death Dis 11(4): 244.
• 490 Li, X., et al. (2020). Sodium Tanshinone IIA Silate Exerts Microcirculation Protective Effects against Spinal Cord Injury In Vitro and In Vivo. Oxid Med Cell Longev 2020: 3949575.
• 491 Li, Y. J., et al. (2020). Targeted role for sphingosine-1-phosphate receptor 1 in cerebrovascular integrity and inflammation during acute ischemic stroke. Neurosci Lett 735: 135160.
• 492 Liew, H., et al. (2020). Modeling Direct and Indirect Action on Cell Survival After Photon Irradiation under Normoxia and Hypoxia. Int J Mol Sci 21(10): 3471.
• 493 Lin, H., et al. (2020). Systemic hypoxia potentiates anti-tumor effects of metformin in hepatocellular carcinoma in mice. Acta Biochim Biophys Sin (Shanghai) 52(4): 421-429.
• 494 Lin, X., et al. (2020). Metallothionein induction attenuates the progression of lung injury in mice exposed to long-term intermittent hypoxia. Inflamm Res 69(1): 15-26.
• 495 Lin, Y., et al. (2020). Atractylon treatment prevents sleep-disordered breathing-induced cognitive dysfunction by suppression of chronic intermittent hypoxia-induced M1 microglial activation. Biosci Rep 40(6).
• 496 Liu, L., et al. (2020). Effects of oxygen generating scaffolds on cell survival and functional recovery following acute spinal cord injury in rats. J Mater Sci Mater Med 31(12): 115.
• 497 Lourenssen, S. R. and M. G. Blennerhassett (2020). M2 Macrophages and Phenotypic Modulation of Intestinal Smooth Muscle Cells Characterize Inflammatory Stricture Formation in Rats. Am J Pathol 190(9): 1843-1858.
• 498 Lu, M., et al. (2020). MiR-134-5p targeting XIAP modulates oxidative stress and apoptosis in cardiomyocytes under hypoxia/reperfusion-induced injury. IUBMB Life 72(10): 2154-2166.
• 499 Lucas, A., et al. (2020). Polymerized human hemoglobin increases the effectiveness of cisplatin-based chemotherapy in non-small cell lung cancer. Oncotarget 11(42): 3770-3781.
• 500 Lv, P., et al. (2020). TANK-binding kinase 1 alleviates myocardial ischemia/reperfusion injury through regulating apoptotic pathway. Biochem Biophys Res Commun 528(3): 574-579.
• 501 Mahiddine, K., et al. (2020). Relief of tumor hypoxia unleashes the tumoricidal potential of neutrophils. J Clin Invest 130(1): 389-403.
• 502 Malhotra, A., et al. (2020). Two-year outcomes of infants enrolled in the first-in-human study of amnion cells for bronchopulmonary dysplasia. Stem Cells Transl Med 9(3): 289-294.
• 503 Mamnoon, B., et al. (2020). Hypoxia-Responsive, Polymeric Nanocarriers for Targeted Drug Delivery to Estrogen Receptor-Positive Breast Cancer Cell Spheroids. Mol Pharm 17(11): 4312-4322.
• 504 Mantripragada, V. P., et al. (2020). Automated in-process characterization and selection of cell-clones for quality and efficient cell manufacturing. Cytotechnology 72(5): 615-627.
• 505 Martens, M. D., et al. (2020). Misoprostol attenuates neonatal cardiomyocyte proliferation through Bnip3, perinuclear calcium signaling, and inhibition of glycolysis. J Mol Cell Cardiol 146: 19-31.
• 506 Martinez, D., et al. (2020). Loss of excitatory amino acid transporter restraint following chronic intermittent hypoxia contributes to synaptic alterations in nucleus tractus solitarii. J Neurophysiol 123(6): 2122-2135.
• 507 Mathuber, M., et al. (2020). Improving the Stability of EGFR Inhibitor Cobalt(III) Prodrugs. Inorg Chem 59(23): 17794-17810.
• 508 Matott, M. P., et al. (2020). Sustained Hypoxia Alters nTS Glutamatergic Signaling and Expression and Function of Excitatory Amino Acid Transporters. Neuroscience 430: 131-140.
• 509 Matsuda, K., et al. (2020). A Rapid Shift from Chronic Hyperoxia to Normoxia Induces Systemic Anaphylaxis via Transient Receptor Potential Ankyrin 1 Channels on Mast Cells. J Immunol 205(11): 2959-2967.
• 510 McCullough, D. J., et al. (2020). Endurance exercise training in pulmonary hypertension increases skeletal muscle electron transport chain supercomplex assembly. Pulm Circ 10(2): 2045894020925762.
• 511 McCullough, D. J., et al. (2020). EXPRESS: Endurance Exercise Training in Pulmonary Hypertension increases Skeletal Muscle Electron Transport Chain Supercomplex Assembly. Pulmonary Circulation: 2045894020925762
• 512 Mei, L., et al. (2020). Rieske iron-sulfur protein induces FKBP12.6/RyR2 complex remodeling and subsequent pulmonary hypertension through NF-kappaB/cyclin D1 pathway. Nat Commun 11(1): 3527.
• 513 Meira, E. C. M., et al. (2020). Putative contributions of circadian clock and sleep in the context of SARS-CoV-2 infection. Eur Respir J 55(6): 2001023.
• 514 Meng, Y., et al. (2020). How Does Chronic Intermittent Hypoxia Influence Upper Airway Stability in Rats? Nat Sci Sleep 12: 749-758.
• 515 Mezu-Ndubuisi, O. J., et al. (2020). Long-term evaluation of retinal morphology and function in a mouse model of oxygen-induced retinopathy. Mol Vis 26: 257-276.
• 516 Moffitt, L. R., et al. (2020). Hypoxia Regulates DPP4 Expression, Proteolytic Inactivation, and Shedding from Ovarian Cancer Cells. Int J Mol Sci 21(21).
• 517 Moreira, A., et al. (2020). Intranasal delivery of human umbilical cord Wharton’s jelly mesenchymal stromal cells restores lung alveolarization and vascularization in experimental bronchopulmonary dysplasia. Stem Cells Transl Med 9(2): 221-234.
• 518 Mostazo, M. G. C., et al. (2020). Metabolic Plasticity Is an Essential Requirement of Acquired Tyrosine Kinase Inhibitor Resistance in Chronic Myeloid Leukemia. Cancers (Basel) 12(11).
• 519 Nagano, N., et al. (2020). Attenuation of Hyperoxic Lung Injury in Newborn Thioredoxin-1-Overexpressing Mice through the Suppression of Proinflammatory Cytokine mRNA Expression. Biomedicines 8(3).
• 520 Nie, H., et al. (2020). O-GlcNAcylation of PGK1 coordinates glycolysis and TCA cycle to promote tumor growth. Nat Commun 11(1): 36.
• 521 Nzou, G., et al. (2020). Multicellular 3D Neurovascular Unit Model for Assessing Hypoxia and Neuroinflammation Induced Blood-Brain Barrier Dysfunction. Sci Rep 10(1): 9766.
• 522 O’Connor, K. M., et al. (2020). Prebiotic administration modulates gut microbiota and faecal short-chain fatty acid concentrations but does not prevent chronic intermittent hypoxia-induced apnoea and hypertension in adult rats. EBioMedicine 59: 102968.
• 523 Ordway, B., et al. (2020). Targeting of Evolutionarily Acquired Cancer Cell Phenotype by Exploiting pHi-Metabolic Vulnerabilities. Cancers (Basel) 13(1).
• 524 O’Reilly, M., et al. (2020). Late Rescue Therapy with Cord-Derived Mesenchymal Stromal Cells for Established Lung Injury in Experimental Bronchopulmonary Dysplasia. Stem Cells Dev 29(6): 364-371.
• 525 Paavola, J., et al. (2020). Vezf1 regulates cardiac structure and contractile function. EBioMedicine 51: 102608.
• 526 Pan, W. M., et al. (2020). miR-210 Participates in Hepatic Ischemia Reperfusion Injury by Forming a Negative Feedback Loop With SMAD4. Hepatology 72(6): 2134-2148.
• 527 Pandey, A., et al. (2020). Heterogeneous surface architectured pH responsive Metal-Drug Nano-conjugates for mitochondria targeted therapy of Glioblastomas: A multimodal intranasal approach. Chemical Engineering Journal 394: 124419.
• 528 Patel, V., et al. (2020). Dietary Antioxidants Significantly Attenuate Hyperoxia-Induced Acute Inflammatory Lung Injury by Enhancing Macrophage Function via Reducing the Accumulation of Airway HMGB1. Int J Mol Sci 21(3): E977.
• 529 Pavlatovska, B., et al. (2020). Lactic Acidosis Interferes With Toxicity of Perifosine to Colorectal Cancer Spheroids: Multimodal Imaging Analysis. Front Oncol 10: 581365.
• 530 Pecher, S. J., et al. (2020). Impact of Short-Term Hypoxia on Sirtuins as Regulatory Elements in HUVECs. J Clin Med 9(8).
• 531 Penaloza, E., et al. (2020). MiR-21-5p directly contributes to regulating eNOS expression in human artery endothelial cells under normoxia and hypoxia. Biochem Pharmacol 182: 114288.
• 532 Peterson, A. L., et al. (2020). Hyperoxic Exposure Caused Lung Lipid Compositional Changes in Neonatal Mice. Metabolites 10(9).
• 533 Polonis, K., et al. (2020). Chronic Intermittent Hypoxia Triggers a Senescence-like Phenotype in Human White Preadipocytes. Sci Rep 10(1): 6846.
• 534 Qiu, T., et al. (2020). DUSP12 protects against hepatic ischemia-reperfusion injury dependent on ASK1-JNK/p38 pathway in vitro and in vivo. Clin Sci (Lond) 134(17): 2279-2294.
• 535 Radhakrishnan, J., et al. (2020). Constitutive cyclophilin-D ablation in mice increases exercise and cognitive-behavioral performance under normoxic and hypoxic conditions. Physiol Behav 219: 112828.
• 536 Reid, S., et al. (2020). Inhibition of BRD4 Reduces Neutrophil Activation and Adhesion to the Vascular Endothelium Following Ischemia Reperfusion Injury. Int J Mol Sci 21(24).
• 537 Ren, J., et al. (2020). Secoisolariciresinol diglucoside improves myocardial injury by regulating TXNIP/NLRP3 signaling pathway in CIH mice. Chinese Pharmacological Bulletin 36(8): 1094-1099.
• 538 Renfrow, J. J., et al. (2020). Attenuating hypoxia driven malignant behavior in glioblastoma with a novel hypoxia-inducible factor 2 alpha inhibitor. Sci Rep 10(1): 15195.
• 539 Revhaug, C., et al. (2020). Pulmonary vascular disease is evident in gene regulation of experimental bronchopulmonary dysplasia. J Matern Fetal Neonatal Med 33(12): 2122-2130.
• 540 Richards, D. J., et al. (2020). Human cardiac organoids for the modelling of myocardial infarction and drug cardiotoxicity. Nat Biomed Eng 4(4): 446-462.
• 541 Roque, J., 3rd, et al. (2020). Strained, Photoejecting Ru(II) Complexes that are Cytotoxic Under Hypoxic Conditions. Photochem Photobiol 96(2): 327-339.
• 542 Rytkonen, K. T., et al. (2020). Transcriptomic responses to hypoxia in endometrial and decidual stromal cells. Reproduction 160(1): 39-51.
• 543 Saldana-Caboverde, A., et al. (2020). Hypoxia Promotes Mitochondrial Complex I Abundance via HIF-1alpha in Complex III and Complex IV Eficient Cells. Cells 9(10).
• 544 Saralkar, P., et al. (2020). Nanoparticle formulation and in vitro efficacy testing of the mitoNEET ligand NL-1 for drug delivery in a brain endothelial model of ischemic reperfusion-injury. Int J Pharm 578: 119090.
• 545 Sareen, N., et al. (2020). Hypoxia-induced downregulation of cyclooxygenase 2 leads to the loss of immunoprivilege of allogeneic mesenchymal stem cells. FASEB J 34(11): 15236-15251.
• 546 Sawant, O. B., et al. (2020). Thyroid Activating Enzyme, Deiodinase II Is Required for Photoreceptor Function in the Mouse Model of Retinopathy of Prematurity. Invest Ophthalmol Vis Sci 61(13): 36.
• 547 Schuffels, S., et al. (2020). Effects of inter-alpha inhibitor proteins on brain injury after exposure of neonatal rats to severe hypoxia-ischemia. Exp Neurol 334: 113442.
• 548 Seimetz, M., et al. (2020). NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD. Nat Metab 2(6): 532-546.
• 549 Seo, S., et al. (2020). Evogliptin, a dipeptidyl peptidase-4 inhibitor, attenuates pathological retinal angiogenesis by suppressing vascular endothelial growth factor-induced Arf6 activation. Exp Mol Med 52(10): 1744-1753.
• 550 Shen, H., et al. (2020). Mononuclear diploid cardiomyocytes support neonatal mouse heart regeneration in response to paracrine IGF2 signaling. eLife 9.
• 551 Shi, L., et al. (2020). Hypoxia-induced hsa_circ_0000826 is linked to liver metastasis of colorectal cancer. J Clin Lab Anal 34(9): e23405.
• 552 Shults, N. V., et al. (2020). Increased Smooth Muscle Kv11.1 Channel Expression in Pulmonary Hypertension and Protective Role of Kv11.1 Channel Blocker Dofetilide. Am J Pathol 190(1): 48-56.
• 553 Shyu, K. G., et al. (2020). Hyperbaric oxygen-induced long non-coding RNA MALAT1 exosomes suppress MicroRNA-92a expression in a rat model of acute myocardial infarction. J Cell Mol Med 24(22): 12945-12954.
• 554 Sidramagowda Patil, S., et al. (2020). Alda-1 Attenuates Hyperoxia-Induced Acute Lung Injury in Mice. Front Pharmacol 11: 597942.
• 555 Silva, M., et al. (2020). Therapeutic Benefit of the Association of Lodenafil with Mesenchymal Stem Cells on Hypoxia-induced Pulmonary Hypertension in Rats. Cells 9(9).
• 556 Singh, C., et al. (2020). Hyperoxia induces glutamine-fuelled anaplerosis in retinal Muller cells. Nat Commun 11(1): 1277.
• 557 Sitapara, R. A., et al. (2020). The alpha7 nicotinic acetylcholine receptor agonist, GTS-21, attenuates hyperoxia-induced acute inflammatory lung injury by alleviating the accumulation of HMGB1 in the airways and the circulation. Mol Med 26(1): 63.
• 558Slocum, J. T., et al. (2020). Design and validation of a device for the mechanical stimulation of bioengineered 3D neo-tissue constructs. Precision Engineering 64: 129-137
• 559 Smith, R. O., et al. (2020). Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin. eLife 9.
• 560 Smolle, E., et al. (2020). Distribution and prognostic significance of gluconeogenesis and glycolysis in lung cancer. Mol Oncol 14(11): 2853-2867.
• 561 Sokolova, V., et al. (2020). Transport of ultrasmall gold nanoparticles (2 nm) across the blood-brain barrier in a six-cell brain spheroid model. Sci Rep 10(1): 18033.
• 562 Son, J.-H., et al. (2020). Dopaminergic Co-Regulation of Locomotor Development and Motor Neuron Synaptogenesis is Uncoupled by Hypoxia in Zebrafish. eneuro
• 563 Song, J. Q., et al. (2020). Heterozygous SOD2 deletion deteriorated chronic intermittent hypoxia-induced lung inflammation and vascular remodeling through mtROS-NLRP3 signaling pathway. Acta Pharmacol Sin 41(9): 1197-1207.
• 564 Spyropoulos, F., et al. (2020). Echocardiographic markers of pulmonary hemodynamics and right ventricular hypertrophy in rat models of pulmonary hypertension. Pulm Circ 10(2): 2045894020910976.
• 565 Steele, A. N., et al. (2020). Multi-phase catheter-injectable hydrogel enables dual-stage protein-engineered cytokine release to mitigate adverse left ventricular remodeling following myocardial infarction in a small animal model and a large animal model. Cytokine 127: 154974.
• 566 Sun, M., et al. (2020). Epithelial Membrane Protein 2 (EMP2) Promotes VEGF-Induced Pathological Neovascularization in Murine Oxygen-Induced Retinopathy. Invest Ophthalmol Vis Sci 61(2): 3.
• 567 Sun, Z. M., et al. (2020). Resveratrol protects against CIH-induced myocardial injury by targeting Nrf2 and blocking NLRP3 inflammasome activation. Life Sci 245: 117362.
• 568 Tang, H., et al. (2020). Protective effects of SS-31 against SDHB suppression-mitochondrial dysfunction-EndMT axis-modulated CBT sclerosis and progression. Am J Transl Res 12(11): 7603-7619.
• 569 Tantingco, G. and M. G. Ryou (2020). Normobaric intermittent hypoxic training regulates microglia phenotype and enhances phagocytic activity. Exp Biol Med (Maywood) 245(8): 740-747.
• 570 Tsai, M. H., et al. (2020). Ischemic Stroke Risk Associated with Mitochondrial Haplogroup F in the Asian Population. Cells 9(8).
• 571 Tsuji, S., et al. (2020). Aggravated brain injury after neonatal hypoxic ischemia in microglia-depleted mice. J Neuroinflammation 17(1): 111.
• 572 Vagaska, B., et al. (2020). Modelling human CNS injury with human neural stem cells in 2- and 3-Dimensional cultures. Sci Rep 10(1): 6785.
• 573 Vazquez-Membrillo, M., et al. (2020). Prolactin stimulates the vascularisation of the retina in newborn mice under hyperoxia conditions. J Neuroendocrinol 32(11): e12858.
• 574 Villasana-Salazar, B., et al. (2020). Chronic intermittent hypoxia transiently increases hippocampal network activity in the gamma frequency band and 4-Aminopyridine-induced hyperexcitability in vitro. Epilepsy Res 166: 106375.
• 575 Vitali, S. H., et al. (2020). Heme oxygenase-1 dampens the macrophage sterile inflammasome response and regulates its components in the hypoxic lung. Am J Physiol Lung Cell Mol Physiol 318(1): L125-L134.
• 576 Vlaski-Lafarge, M., et al. (2020). Normal Hematopoetic Stem and Progenitor Cells Can Exhibit Metabolic Flexibility Similar to Cancer Cells. Front Oncol 10(713): 713.
• 577 Voss, D. M., et al. (2020). The Alternative Splicing Factor, MBNL1, Inhibits Glioblastoma Tumor Initiation and Progression by Reducing Hypoxia-Induced Stemness. Cancer Res 80(21): 4681-4692.
• 578 Wang, J., et al. (2020). Stress Signal Regulation by Na/K-ATPase As a New Approach to Promote Physiological Revascularization in a Mouse Model of Ischemic Retinopathy. Invest Ophthalmol Vis Sci 61(14): 9.
• 579 Wang, L., et al. (2020). Galectin-3 expression and secretion by tumor-associated macrophages in hypoxia promotes breast cancer progression. Biochem Pharmacol 178: 114113.
• 580 Wang, S., et al. (2020). Typhae pollen polysaccharides protect hypoxia-induced PC12 cell injury via regulation of miR-34a/SIRT1. Int J Immunopathol Pharmacol 34: 2058738420910005.
• 581 Wang, T. T., et al. (2020). Transcriptional Profile Alteration of Peripheral Blood in Chronic Hypoxia. Chin Med Sci J 35(1): 54-64.
• 582 Wang, X., et al. (2020). Role of miR-326 in neonatal hypoxic-ischemic brain damage pathogenesis through targeting of the delta-opioid receptor. Mol Brain 13(1): 51.
• 583 Wang, Y., et al. (2020). Drag-reducing polymers attenuates pulmonary vascular remodeling and right ventricular dysfunction in a rat model of chronic hypoxia-induced pulmonary hypertension. Clin Hemorheol Microcirc 74(2): 189-200.
• 584 Wang, Y., et al. (2020). Ex-vivo treatment of allografts using adipose-derived stem cells induced prolonged rejection-free survival in an allogenic hind-limb transplantation model. Annals of Translational Medicine 8(14): 867.
• 585 Wedgwood, S., et al. (2020). Intestinal Dysbiosis and the Developing Lung: The Role of Toll-Like Receptor 4 in the Gut-Lung Axis. Front Immunol 11: 357.
• 586 Wedgwood, S., et al. (2020). The developing gut-lung axis: postnatal growth restriction, intestinal dysbiosis, and pulmonary hypertension in a rodent model. Pediatr Res 87(3): 472-479.
• 587 Wei, S. T., et al. (2020). Atypical chemokine receptor ACKR3/CXCR7 controls postnatal vasculogenesis and arterial specification by mesenchymal stem cells via Notch signaling. Cell Death Dis 11(5): 307.
• 588 Willis, G. R., et al. (2020). Mesenchymal stromal cell-derived small extracellular vesicles restore lung architecture and improve exercise capacity in a model of neonatal hyperoxia-induced lung injury. J Extracell Vesicles 9(1): 1790874.
• 589 Willis, K. A., et al. (2020). Perinatal maternal antibiotic exposure augments lung injury in offspring in experimental bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol 318(2): L407-L418.
• 590 Winter, M. P., et al. (2020). Interruption of vascular endothelial growth factor receptor 2 signaling induces a proliferative pulmonary vasculopathy and pulmonary hypertension. Basic Res Cardiol 115(6): 58.
• 591 Wong, M. K., et al. (2020). Establishment of an in vitro placental barrier model cultured under physiologically relevant oxygen levels. Mol Hum Reprod 26(5): 353-365.
• 592 Wu, W., et al. (2020). PI3Kdelta as a Novel Therapeutic Target in Pathological Angiogenesis. Diabetes 69(4): 736-748.
• 593 Xie, S., et al. (2020). Andrographolide Protects Against Adverse Cardiac Remodeling After Myocardial Infarction through Enhancing Nrf2 Signaling Pathway. Int J Biol Sci 16(1): 12-26.
• 594Xing, Y., et al. (2020). A novel neonatal rat model of bronchopulmonary dysplasia complicated by pulmonary hypertension established by high-low oxygen bidirectional induction. Journal of China Medical University 49(9): 846-853
• 595 Xu, W., et al. (2020). TRAF5 protects against myocardial ischemia reperfusion injury via AKT signaling. Eur J Pharmacol 878: 173092.
• 596 Yadav, A. K., et al. (2020). An Activity-Based Sensing Approach for the Detection of Cyclooxygenase-2 in Live Cells. Angew Chem Int Ed Engl 59(8): 3307-3314.
• 597 Yang, J. H., et al. (2020). Regulation of Cellular Stress Signaling in Bladder Ischemia. Res Rep Urol 12: 391-402.
• 598 Yang, Y., et al. (2020). An Interplay Between MRTF-A and the Histone Acetyltransferase TIP60 Mediates Hypoxia-Reoxygenation Induced iNOS Transcription in Macrophages. Front Cell Dev Biol 8: 484.
• 599 Yao, X., et al. (2020). Vanillic Acid Alleviates Acute Myocardial Hypoxia/Reoxygenation Injury by Inhibiting Oxidative Stress. Oxid Med Cell Longev 2020: 8348035.
• 600 Yin, X., et al. (2020). Effects of Glucose Deprivation on ATP and Proteoglycan Production of Intervertebral Disc Cells under Hypoxia. Sci Rep 10(1): 8899.
• 601Young, H. E. and M. O. Speight (2020). Informed Consent Guidelines for Optimizing the Use of Telomerase-Positive Stem Cells. J Reg Med Biol Res 1(1): 1-20
• 602Yuan, J., et al. (2020). MicroRNA-421 protects against chronic intermittent hypoxia-induced vascular endothelial cell injury by targeting TLR4. Tropical Journal of Pharmaceutical Research 19(3): 525-532
• 603 Yuan, X., et al. (2020). Hypoxic preconditioning enhances the differentiation of bone marrow stromal cells into mature oligodendrocytes via the mTOR/HIF-1alpha/VEGF pathway in traumatic brain injury. Brain Behav 10(7): e01675.
• 604 Zambuto, S. G., et al. (2020). Response of neuroglia to hypoxia-induced oxidative stress using enzymatically crosslinked hydrogels. MRS Commun 10(1): 83-90.
• 605 Zasada, M., et al. (2020). Short- and long-term impact of hyperoxia on the blood and retinal cells’ transcriptome in a mouse model of oxygen-induced retinopathy. Pediatr Res 87(3): 485-493.
• 606 Zemskova, M., et al. (2020). Necrosis-Released HMGB1 (High Mobility Group Box 1) in the Progressive Pulmonary Arterial Hypertension Associated With Male Sex. Hypertension 76(6): 1787-1799.
• 607 Zhang, H., et al. (2020). MicroRNA137 regulates hypoxiamediated migration and epithelialmesenchymal transition in prostate cancer by targeting LGR4 via the EGFR/ERK signaling pathway. Int J Oncol 57(2): 540-549.
• 608 Zhang, J., et al. (2020). Expression of sirtuin type 3 in locus ceruleus is associated with long-term intermittent hypoxia-induced neurocognitive impairment in mice. NeuroReport 31(3): 220-225
• 609 Zhang, J., et al. (2020). Hypoxia Enhances Mesenchymal Characteristics Maintenance of Buffalo Bone Marrow-Derived Mesenchymal Stem Cells. Cell Reprogram 22(3): 167-177.
• 610 Zhang, J., et al. (2020). MicroRNA-210 improves perfusion recovery following hindlimb ischemia via suppressing reactive oxygen species. Exp Ther Med 20(6): 236.
• 611 Zhang, J., et al. (2020). Potential Role of mRNAs and LncRNAs in Chronic Intermittent Hypoxia Exposure-Aggravated Atherosclerosis. Front Genet 11: 290.
• 612 Zhang, L., et al. (2020). Impaired Autophagic Activity Contributes to the Pathogenesis of Bronchopulmonary Dysplasia. Evidence from Murine and Baboon Models. Am J Respir Cell Mol Biol 63(3): 338-348.
• 613 Zhang, P., et al. (2020). Agrin Involvement in Synaptogenesis Induced by Exercise in a Rat Model of Experimental Stroke. Neurorehabil Neural Repair 34(12): 1124-1137.
• 614 Zhang, Q., et al. (2020). Globular adiponectin alleviates chronic intermittent hypoxia-induced H9C2 cardiomyocytes apoptosis via ER-phagy induction. Cell Cycle 19(22): 3140-3153.
• 615 Zhao, S., et al. (2020). Hypothermia-Induced Ubiquitination of Voltage-Dependent Anion Channel 3 Protects BV2 Microglia Cells From Cytotoxicity Following Oxygen-Glucose Deprivation/Recovery. Front Mol Neurosci 13: 100.
• 616 Zhao, Y., et al. (2020). [Effects of Xiaotan Huayu Liqiao Formula on cognitive impairment in mice exposed to chronic intermittent hypoxia]. Zhongguo Ying Yong Sheng Li Xue Za Zhi 36(2): 143-147.
• 617 Zhao, Y., et al. (2020). GDF11 enhances therapeutic efficacy of mesenchymal stem cells for myocardial infarction via YME1L-mediated OPA1 processing. Stem Cells Transl Med 9(10): 1257-1271.
• 618 Zhao, Y., et al. (2020). Gene-environment regulation of chamber-specific maturation during hypoxemic perinatal circulatory transition. J Mol Med (Berl) 98(7): 1009-1020.
• 619 Zhu, S., et al. (2020). IGFBPrP1silencing promotes hypoxiainduced angiogenic potential of choroidal endothelial cells via the RAF/MEK/ERK signaling pathway. Mol Med Rep 22(6): 4837-4847.
• 620 Zions, M., et al. (2020). Nest Carbon Dioxide Masks GABA-Dependent Seizure Susceptibility in the Naked Mole-Rat. Curr Biol 30(11): 2068-2077 e2064.
• 621 Abdulnour-Nakhoul, S., et al. (2019). Effects of chronic hypercapnia on ammonium transport in the mouse kidney. Physiol Rep 7(16): e14221.
• 622 Abu-El-Rub, E., et al. (2019). Hypoxia-induced 26S proteasome dysfunction increases immunogenicity of mesenchymal stem cells. Cell Death Dis 10(2): 90.
• 623 Accorsi-Mendonca, D., et al. (2019). Astrocytic modulation of glutamatergic synaptic transmission is reduced in NTS of rats submitted to short-term sustained hypoxia. J Neurophysiol 121(5): 1822-1830.
• 624 Al Khazal, F., et al. (2019). A conditional mouse model of complex II deficiency manifesting as Leigh-like syndrome. FASEB J 33(12): 13189-13201.
• 625 Al-Ahmad, A. J., et al. (2019). Hyaluronan impairs the barrier integrity of brain microvascular endothelial cells through a CD44-dependent pathway. Journal of Cerebral Blood Flow & Metabolism 39(9): 1759-1775
• 626 Alakoski, T., et al. (2019). Inhibition of cardiomyocyte Sprouty1 protects from cardiac ischemia-reperfusion injury. Basic Res Cardiol 114(2): 7.
• 627 Alleboina, S., et al. (2019). Dual specificity phosphatase 5 regulates perfusion recovery in experimental peripheral artery disease. Vasc Med 24(5): 395-404.
• 628 Armond, R. D., et al. (2019). 0285 Sex As A Biological Variable On The Inflammatory Effects Of Intermittent Hypoxia. Sleep 42(Supplement_1): A116-A116.
• 629 Ashraf, S., et al. (2019). CAMKII as a therapeutic target for growth factor-induced retinal and choroidal neovascularization. JCI Insight 4(6).
• 630 Atay, C., et al. (2019). BRAF Targeting Sensitizes Resistant Melanoma to Cytotoxic T Cells. Clin Cancer Res 25(9): 2783-2794.
• 631 Banach, A., et al. (2019). CEMIP upregulates BiP to promote breast cancer cell survival in hypoxia. Oncotarget 10(42): 4307-4320.
• 632 Barrios-Anderson, A., et al. (2019). Inter-alpha Inhibitor Proteins Modulate Neuroinflammatory Biomarkers After Hypoxia-Ischemia in Neonatal Rats. J Neuropathol Exp Neurol.
• 633 Bavis, R. W., et al. (2019). Combined effects of intermittent hyperoxia and intermittent hypercapnic hypoxia on respiratory control in neonatal rats. Respir Physiol Neurobiol 260: 70-81.
• 634 Bazilio, D. S., et al. (2019). Cardiovascular and respiratory profiles during the sleep-wake cycle of rats previously submitted to chronic intermittent hypoxia. Exp Physiol 104(9): 1408-1419.
• 635 Bensaid, S., et al. (2019). Impact of different methods of induction of cellular hypoxia: focus on protein homeostasis signaling pathways and morphology of C2C12 skeletal muscle cells differentiated into myotubes. J Physiol Biochem 75(3): 367-377.
• 636 Berahovich, R., et al. (2019). Hypoxia Selectively Impairs CAR-T Cells In Vitro. Cancers (Basel) 11(5): 602.
• 637 Bernard, A., et al. (2019). Cigarette smoke extract exacerbates hyperpermeability of cerebral endothelial cells after oxygen glucose deprivation and reoxygenation. Sci Rep 9(1): 15573.
• 638 Binch, A. L. A., et al. (2019). Combinatorial conditioning of adipose derived-mesenchymal stem cells enhances their neurovascular potential: Implications for intervertebral disc degeneration. JOR spine 2(4): e1072.
• 639 Blackwood, E. A., et al. (2019). Pharmacologic ATF6 activation confers global protection in widespread disease models by reprograming cellular proteostasis. Nat Commun 10(1): 187.
• 640 Brandolini, L., et al. (2019). The Novel C5aR Antagonist DF3016A Protects Neurons Against Ischemic Neuroinflammatory Injury. Neurotoxicity Research: 1-12
• 641 Buceta, P. M. R., et al. (2019). The kynurenine pathway is essential for rhodoquinone biosynthesis in Caenorhabditis elegans. Journal of Biological Chemistry 294(28): 11047-11053
• 642 Cahill, L. S., et al. (2019). Fetal brain sparing in a mouse model of chronic maternal hypoxia. J Cereb Blood Flow Metab 39(6): 1172-1184.
• 643 Cai, M., et al. (2019). Profiling the Gene Expression and DNA Methylation in the Mouse Brain after Ischemic Preconditioning. Neuroscience 406: 249-261.
• 644 Campillo, N., et al. (2019). Differential Oxygenation in Tumor Microenvironment Modulates Macrophage and Cancer Cell Crosstalk: Novel Experimental Setting and Proof of Concept. Front Oncol 9: 43.
• 645 Carrasco-Wong, I., et al. (2019). Human umbilical artery endothelial cells from Large-for-Gestational-Age newborn have increased antioxidant efficiency and gene expression. J Cell Physiol 234(10): 18571-18586.
• 646 Cengiz, P., et al. (2019). Developmental differences in microglia morphology and gene expression during normal brain development and in response to hypoxia-ischemia. Neurochem Int 127: 137-147.
• 647 Chabi, S., et al. (2019). Hypoxia Regulates Lymphoid Development of Human Hematopoietic Progenitors. Cell Rep 29(8): 2307-2320 e2306.
• 648 Chai, N., et al. (2019). Spermidine Prevents Heart Injury in Neonatal Rats Exposed to Intrauterine Hypoxia by Inhibiting Oxidative Stress and Mitochondrial Fragmentation. Oxid Med Cell Longev 2019: 5406468.
• 649 Chao, C. M., et al. (2019). Impact of Fgf10 deficiency on pulmonary vasculature formation in a mouse model of bronchopulmonary dysplasia. Hum Mol Genet 28(9): 1429-1444.
• 650 Chen, C. M. and H. C. Chou (2019). Maternal inflammation exacerbates neonatal hyperoxia-induced kidney injury in rat offspring. Pediatr Res 86(2): 174-180.
• 651 Chen, P. Y., et al. (2019). Glial response to hypoxia in mutants of NPAS1/3 homolog Trachealess through Wg signaling to modulate synaptic bouton organization. PLoS Genet 15(8): e1007980.
• 652 Chen, X., et al. (2019). Neuroprotective effects of inter-alpha inhibitor proteins after hypoxic-ischemic brain injury in neonatal rats. Exp Neurol 317: 244-259.
• 653 Chiblak, S., et al. (2019). Carbon irradiation overcomes glioma radioresistance by eradicating stem cells and forming an antiangiogenic and immunopermissive niche. JCI Insight 4(2).
• 654 Chioua, M., et al. (2019). New Quinolylnitrones for Stroke Therapy: Antioxidant and Neuroprotective ( Z)- N- tert-Butyl-1-(2-chloro-6-methoxyquinolin-3-yl)methanimine Oxide as a New Lead-Compound for Ischemic Stroke Treatment. J Med Chem 62(4): 2184-2201.
• 655 Chu, A., et al. (2019). The Placental Transcriptome in Late Gestational Hypoxia Resulting in Murine Intrauterine Growth Restriction Parallels Increased Risk of Adult Cardiometabolic Disease. Sci Rep 9(1): 1243.
• 656 Clements, R. T., et al. (2019). Treatment of Pulmonary Hypertension With Angiotensin II Receptor Blocker and Neprilysin Inhibitor Sacubitril/Valsartan. Circ Heart Fail 12(11): e005819.
• 657 Cole, A. R., et al. (2019). Safety of inhaled hydrogen gas in healthy mice. Med Gas Res 9(3): 133-138.
• 658 Coronado, R. E., et al. (2019). Hepatocyte-like cells derived from human amniotic epithelial, bone marrow, and adipose stromal cells display enhanced functionality when cultured on decellularized liver substrate. Stem cell research: 101471
• 659 Coronel, M., et al. (2019). Oxygen generating biomaterial improves the function and efficacy of beta cells within a macroencapsulation device. Biomaterials
• 660 Coyle, R., et al. (2019). The Effects of Metabolic Substrate Availability on Human Adipose-Derived Stem Cell Spheroid Survival. Tissue Eng Part A 25(7-8): 620-631.
• 661 Crnkovic, S., et al. (2019). Disconnect between Fibrotic Response and Right Ventricular Dysfunction. Am J Respir Crit Care Med 199(12): 1550-1560.
• 662 da Silva, M. P., et al. (2019). Hyperexcitability and plasticity induced by sustained hypoxia on rectus abdominis motoneurons. J Physiol 597(7): 1935-1956.
• 663 Dai, X., et al. (2019). Scaling up the Manufacturing Process of Adoptive T Cell Immunotherapy. Biotechnol J 14(4): e1800239.
• 664 Daviaud, N., et al. (2019). Distinct Vulnerability and Resilience of Human Neuroprogenitor Subtypes in Cerebral Organoid Model of Prenatal Hypoxic Injury. Front Cell Neurosci 13: 336.
• 665 Deng, Y., et al. (2019). Hypoxia enhances buffalo adipose‐derived mesenchymal stem cells proliferation, stemness, and reprogramming into induced pluripotent stem cells. Journal of Cellular Physiology 234(10): 17254-17268.
• 666 Dereli, A. S., et al. (2019). Adaptation of Respiratory-Related Brain Regions to Long-Term Hypercapnia: Focus on Neuropeptides in the RTN. Front Neurosci 13: 1343.
• 667 Desjarlais, M., et al. (2019). MicroRNA expression profile in retina and choroid in oxygen-induced retinopathy model. PLOS ONE 14(6): e0218282.
• 668 Dikalova, A. E., et al. (2019). Reactive oxygen species modulate Na(+)-coupled neutral amino acid transporter 1 expression in piglet pulmonary arterial endothelial cells. Am J Physiol Heart Circ Physiol 316(4): H911-H919.
• 669 do Carmo, J. M., et al. (2019). Role of melanocortin 4 receptor in hypertension induced by chronic intermittent hypoxia. Acta Physiol (Oxf) 225(4): e13222.
• 670Dominguez, C. P., et al. (2019). Sensitivity to hypoxia and microbial activity are instrumental in pericarp-imposed dormancy expression in sunflower (Helianthus annuus L.). Seed Science Research: 1-12
• 671 Doshi, S., et al. (2019). Neuropeptide signaling regulates the susceptibility of developing C. elegans to anoxia. Free Radic Biol Med 131: 197-208.
• 672 Dumas, P. Y., et al. (2019). Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib via STAT5-and hypoxia-dependent upregulation of AXL. Haematologica 104(10): 2017-2027.
• 673 Endesfelder, S., et al. (2019). Antioxidative effects of caffeine in a hyperoxia-based rat model of bronchopulmonary dysplasia. Respir Res 20(1): 88.
• 674 Erber, L., et al. (2019). Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation. Mol Cell Proteomics 18(9): 1772-1781.
• 675Esen, N., et al. (2019). Endogenous Adaptation to Chronic Mild Hypoxia Shifts the Balance towards Anti-Inflammatory Milieu in Progressive Myelin Oligodendrocyte Glycoprotein Induced EAE. Int J Neurodegener Dis 2(011)
• 676 Evans, R. G. (2019). Another step forward for methods for studying renal oxygenation. Kidney Int 96(3): 552-554.
• 677 Fan, F., et al. (2019). Rapamycin as a potential treatment for succinate dehydrogenase deficiency. Heliyon 5(2): e01217.
• 678 Ferro, T., et al. (2019). Successful isolation and ex vivo expansion of human mesenchymal stem/stromal cells obtained from different synovial tissue-derived (biopsy) samples. J Cell Physiol 234(4): 3973-3984.
• 679 Fragopoulou, A. F., et al. (2019). Can Neonatal Systemic Inflammation and Hypoxia Yield a Cerebral Palsy-Like Phenotype in Periadolescent Mice? Mol Neurobiol 56(10): 6883-6900.
• 680 Fukumoto, J., et al. (2019). Oxidative stress induces club cell proliferation and pulmonary fibrosis in Atp8b1 mutant mice. Aging (Albany NY) 11(1): 209-229.
• 681 Ge, M. Q., et al. (2019). Differential metabolic and inflammatory responses to intermittent hypoxia in substrains of lean and obese C57BL/6 mice. Life Sci 238: 116959.
• 682 Geranurimi, A., et al. (2019). Probing Anti-inflammatory Properties Independent of NF-κB Through Conformational Constraint of Peptide-Based Interleukin-1 Receptor Biased Ligands. Frontiers in chemistry 7: 23.
• 683 Gerby, S., et al. (2019). Hypoxia/hypercapnia prevents iron-dependent cold injuries in cord blood stem and progenitor cells. Cytotherapy 21(4): 460-467.
• 684 Goloshvili, G., et al. (2019). Sodium nitroprusside induces H-Ras depalmitoylation and alters the cellular response to hypoxia in differentiated and undifferentiated PC12 cells. Cell Biochem Funct 37(7): 545-552.
• 685 Goto, T., et al. (2019). ATP produced by anaerobic glycolysis is essential for enucleation of human erythroblasts. Exp Hematol 72: 14-26 e11.
• 686 Greenshields, A. L., et al. (2019). The anti-malarial drug artesunate causes cell cycle arrest and apoptosis of triple-negative MDA-MB-468 and HER2-enriched SK-BR-3 breast cancer cells. Exp Mol Pathol 107: 10-22.
• 687 Guan, P., et al. (2019). Hydrogen gas alleviates chronic intermittent hypoxia-induced renal injury through reducing iron overload. Molecules 24(6): 1184
• 688 Guan, P., et al. (2019). Hydrogen protects against chronic intermittent hypoxia induced renal dysfunction by promoting autophagy and alleviating apoptosis. Life Sci 225: 46-54.
• 689 Guan, P., et al. (2019). Resveratrol prevents chronic intermittent hypoxia-induced cardiac hypertrophy by targeting the PI3K/AKT/mTOR pathway. Life Sci 233: 116748.
• 690 Gugliandolo, A., et al. (2019). The Role of Hypoxia on the Neuronal Differentiation of Gingival Mesenchymal Stem Cells: A Transcriptional Study. Cell Transplant 28(5): 538-552.
• 691 Halder, S. K. and R. Milner (2019). A critical role for microglia in maintaining vascular integrity in the hypoxic spinal cord. Proc Natl Acad Sci U S A 116(51): 26029-26037.
• 692 Han, J. S., et al. (2019). Hypoxia Restrains Lipid Utilization via Protein Kinase A and Adipose Triglyceride Lipase Downregulation through Hypoxia-Inducible Factor. Mol Cell Biol 39(2): e00390-00318.
• 693 Han, X., et al. (2019). Enhancing Retinal Endothelial Glycolysis by Inhibiting UCP2 Promotes Physiologic Retinal Vascular Development in a Model of Retinopathy of Prematurity. Invest Ophthalmol Vis Sci 60(5): 1604-1613.
• 694 Hao, S., et al. (2019). 2-Methoxyestradiol attenuates chronic-intermittent-hypoxia-induced pulmonary hypertension through regulating microRNA-223. J Cell Physiol 234(5): 6324-6335.
• 695 Hawkins, A. G., et al. (2019). Microenvironmental Factors Drive Tenascin C and Src Cooperation to Promote Invadopodia Formation in Ewing Sarcoma. Neoplasia 21(10): 1063-1072.
• 696 He, J., et al. (2019). Identification and functional analysis of the Mandarin fish (Siniperca chuatsi) hypoxia-inducible factor-1alpha involved in the immune response. Fish Shellfish Immunol 92: 141-150.
• 697 Heiduschka, P., et al. (2019). Different effects of various anti-angiogenic treatments in an experimental mouse model of retinopathy of prematurity. Clin Exp Ophthalmol 47(1): 79-87.
• 698 Hsu, H. L., et al. (2019). Chloramphenicol Induces Autophagy and Inhibits the Hypoxia Inducible Factor-1 Alpha Pathway in Non-Small Cell Lung Cancer Cells. Int J Mol Sci 20(1): 157.
• 699 Hudalla, H., et al. (2019). Carbonic Anhydrase Inhibition Ameliorates Inflammation and Experimental Pulmonary Hypertension. Am J Respir Cell Mol Biol 61(4): 512-524.
• 700 Huizenga, M. N., et al. (2019). Preclinical safety and efficacy of cannabidivarin for early life seizures. Neuropharmacology 148: 189-198.
• 701Hurskainen, M. K., et al. (2019). Multiplexed single-cell transcriptomic analysis of normal and impaired lung development in the mouse. bioRxiv: 868802
• 702 Imamura, T., et al. (2019). Intermittent hypoxia and hypercapnia induces inhibitor of nuclear factor-kappaB kinase subunit beta-dependent atherosclerosis in pulmonary arteries. Am J Physiol Regul Integr Comp Physiol 317(6): R763-R769.
• 703 Jackson-Weaver, O., et al. (2019). Hypoxia/reoxygenation decreases endothelial glycocalyx via reactive oxygen species and calcium signaling in a cellular model for shock. J Trauma Acute Care Surg 87(5): 1070-1076.
• 704 Jeyarajah, M. J., et al. (2019). Syndecan-4 regulates extravillous trophoblast migration by coordinating protein kinase C activation. Sci Rep 9(1): 10175.
• 705 Jin, J., et al. (2019). Human natural killer cell manufacturing using a closed system process for patients with metastatic solid tumors or hematologic malignancies. Cytotherapy 21(5): S37.
• 706 Josephrajan, A., et al. (2019). Unconventional Secretion of Adipocyte Fatty Acid Binding Protein 4 Is Mediated By Autophagic Proteins in a Sirtuin-1-Dependent Manner. Diabetes 68(9): 1767-1777.
• 707 Joshi, S., et al. (2019). Hypoxic regulation of angiotensin-converting enzyme 2 and Mas receptor in human CD34(+) cells. J Cell Physiol 234(11): 20420-20431.
• 708 Kaiser, S., et al. (2019). Neuroprotection after Hemorrhagic Stroke Depends on Cerebral Heme Oxygenase-1. Antioxidants (Basel) 8(10): 496.
• 709 Keshavarz, A., et al. (2019). CAR, a Homing Peptide, Prolongs Pulmonary Preferential Vasodilation by Increasing Pulmonary Retention and Reducing Systemic Absorption of Liposomal Fasudil. Mol Pharm 16(8): 3414-3429.
• 710 Keskin, I., et al. (2019). The molecular pathogenesis of superoxide dismutase 1-linked ALS is promoted by low oxygen tension. Acta Neuropathol 138(1): 85-101.
• 711 Kline, D. D., et al. (2019). TrpV1 channels contribute to spontaneous glutamate release in nucleus tractus solitarius (nTS) following chronic intermittent hypoxia (CIH). Journal of neurophysiology
• 712 Komabayashi-Suzuki, M., et al. (2019). Spatiotemporally Dependent Vascularization Is Differently Utilized among Neural Progenitor Subtypes during Neocortical Development. Cell Rep 29(5): 1113-1129 e1115.
• 713 Kong, D., et al. (2019). Inhibition of glycogen synthase kinase 3beta protects liver against ischemia/reperfusion injury by activating 5′ adenosine monophosphate-activated protein kinase-mediated autophagy. Hepatol Res 49(4): 462-472.
• 714 Kwee, E., et al. (2019). Quantifying proliferative and surface marker heterogeneity in colony-founding connective tissue progenitors and their progeny using time-lapse microscopy. J Tissue Eng Regen Med 13(2): 203-216.
• 715 Lackner, M., et al. (2019). Cryptic species of Aspergillus section Terrei display essential physiological features to cause infection and are similar in their virulence potential in Galleria mellonella. Virulence 10(1): 542-554.
• 716 Laouafa, S., et al. (2019). Erythropoietin and caffeine exert similar protective impact against neonatal intermittent hypoxia: Apnea of prematurity and sex dimorphism. Exp Neurol 320: 112985.
• 717 Laouafa, S., et al. (2019). Roles of oestradiol receptor alpha and beta against hypertension and brain mitochondrial dysfunction under intermittent hypoxia in female rats. Acta Physiol (Oxf) 226(2): e13255.
• 718 Latorre-Pellicer, A., et al. (2019). Regulation of Mother-to-Offspring Transmission of mtDNA Heteroplasmy. Cell Metab 30(6): 1120-1130 e1125.
• 719 Lau, G. W., et al. (2019). Pdk-1/Hif-1α Ratios Define Geniohyoid Muscle Fiber Phenotypes. International Journal of Sciences 8(7): 11-19.
• 720 Leary, S., et al. (2019). Genetic Strain and Sex Differences in a Hyperoxia-Induced Mouse Model of Varying Severity of Bronchopulmonary Dysplasia. Am J Pathol 189(5): 999-1014.
• 721 Lee, D. E., et al. (2019). Mitochondrial mRNA translation initiation contributes to oxidative metabolism in the myocardia of aged, obese mice. Exp Gerontol 121: 62-70.
• 722 Lee, R. H., et al. (2019). Palmitic acid methyl ester is a novel neuroprotective agent against cardiac arrest. Prostaglandins Leukot Essent Fatty Acids 147: 6-14.
• 723 Lee, R. H.-C., et al. (2019). Palmitic acid methyl ester is a novel neuroprotective agent against cardiac arrest. Prostaglandins, Leukotrienes and Essential Fatty Acids 147: 6-14.
• 724 Lee, S., et al. (2019). CCN1-Yes-Associated Protein Feedback Loop Regulates Physiological and Pathological Angiogenesis. Mol Cell Biol 39(18): MCB.00107-00119.
• 725 Lee, S., et al. (2019). Developing a flow cytometry-based quantitative ido assay to measure immune potency of mesenchymal stromal cells product for phase i clinical trial. Cytotherapy 21(5): S37-S38.
• 726 Lees, J. G., et al. (2019). Oxygen Regulates Human Pluripotent Stem Cell Metabolic Flux. Stem Cells Int 2019: 8195614.
• 727 Li, F., et al. (2019). Neuroprotective Effects of AG490 in Neonatal Hypoxic-Ischemic Brain Injury. Mol Neurobiol 56(12): 8109-8123.
• 728 Li, J. W., et al. (2019). Mesenchymal stromal cells-derived exosomes alleviate ischemia/reperfusion injury in mouse lung by transporting anti-apoptotic miR-21-5p. Eur J Pharmacol 852: 68-76.
• 729 Li, J., et al. (2019). Endothelin-1 enhanced carotid body chemosensory activity in chronic intermittent hypoxia through PLC, PKC and p38MAPK signaling pathways. Neuropeptides 74: 44-51.
• 730 Li, L., et al. (2019). FoxO3 activation in hypoxic tubules prevents chronic kidney disease. J Clin Invest 129(6): 2374-2389.
• 731 Li, N., et al. (2019). Anti-apoptotic effect of interleukin-17 in a mouse model of oxygen-induced retinopathy. Exp Eye Res 187: 107743.
• 732 Li, R., et al. (2019). Autophagy: a new mechanism for regulating VEGF and PEDF expression in retinal pigment epithelium cells. Int J Ophthalmol 12(4): 557-562.
• 733 Li, W. Y., et al. (2019). Transient upregulation of TASK-1 expression in the hypoglossal nucleus during chronic intermittent hypoxia is reduced by serotonin 2A receptor antagonist. J Cell Physiol 234(10): 17886-17895.
• 734 Lima-Ojeda, J. M., et al. (2019). Altered prepulse inhibition of the acoustic startle response in BDNF-deficient mice in a model of early postnatal hypoxia: implications for schizophrenia. Eur Arch Psychiatry Clin Neurosci 269(4): 439-447.
• 735 Lima‐Silveira, L., et al. (2019). Enhancement of excitatory transmission in NTS neurons projecting to ventral medulla of rats exposed to sustained hypoxia is blunted by minocycline. The Journal of physiology
• 736 Liu, B., et al. (2019). Hypoxia-induced autophagy promotes EGFR loss in specific cell contexts, which leads to cell death and enhanced radiosensitivity. Int J Biochem Cell Biol 111: 12-18.
• 737 Liu, Y., et al. (2019). Commitment to Aerobic Glycolysis Sustains Immunosuppression of Human Mesenchymal Stem Cells. Stem Cells Transl Med 8(1): 93-106.
• 738 Liu, Y., et al. (2019). Vascular endothelial growth factor regulation of endothelial nitric oxide synthase phosphorylation is involved in isoflurane cardiac preconditioning. Cardiovasc Res 115(1): 168-178.
• 739 Lu, W. J., et al. (2019). New therapeutic strategy of hinokitiol in haemorrhagic shock-induced liver injury. J Cell Mol Med 23(3): 1723-1734.
• 740Luisetto, M., et al. (2019). The association between hypoxia, chronic ischemia and alters prostate structure and progress of chronic prostatic disease.
• 741 Luo, F., et al. (2019). Invasive Hemodynamic Assessment for the Right Ventricular System and Hypoxia-Induced Pulmonary Arterial Hypertension in Mice. J Vis Exp(152): e60090.
• 742 Luo, Y., et al. (2019). CD146-HIF-1alpha hypoxic reprogramming drives vascular remodeling and pulmonary arterial hypertension. Nat Commun 10(1): 3551.
• 743 Macheda, T., et al. (2019). Chronic Intermittent Hypoxia Induces Robust Astrogliosis in an Alzheimer’s Disease-Relevant Mouse Model. Neuroscience 398: 55-63.
• 744 Mahiddine, K., et al. (2019). Relief of tumor hypoxia unleashes the tumoricidal potential of neutrophils. The Journal of clinical investigation 130(1)
• 745 Maurer, E., et al. (2019). Hypoxia Decreases Diagnostic Biomarkers for Aspergillosis In Vitro. J Fungi (Basel) 5(3): 61.
• 746 Mendez-Sanchez, J. F. and W. W. Burggren (2019). Hypoxia-induced developmental plasticity of larval growth, gill and labyrinth organ morphometrics in two anabantoid fish: The facultative air-breather Siamese fighting fish (Betta splendens) and the obligate air-breather the blue gourami (Trichopodus trichopterus). J Morphol 280(2): 193-204.
• 747 Menneteau, T., et al. (2019). Mass Spectrometry-based Absolute Quantification of 20S Proteasome Status for Controlled Ex-vivo Expansion of Human Adipose-derived Mesenchymal Stromal/Stem Cells. Mol Cell Proteomics 18(4): 744-759.
• 748 Mezu-Ndubuisi, O. J., et al. (2019). Intravitreal Delivery of VEGF-A165-loaded PLGA Microparticles Reduces Retinal Vaso-Obliteration in an In Vivo Mouse Model of Retinopathy of Prematurity. Curr Eye Res 44(3): 275-286.
• 749 Mezu-Ndubuisi, O. J., et al. (2019). Simultaneous assessment of aberrant retinal vascularization, thickness, and function in an in vivo mouse oxygen-induced retinopathy model. Eye (Lond) 33(3): 363-373.
• 750 Mian, M. O. R., et al. (2019). TLR (Toll-Like Receptor) 4 Antagonism Prevents Left Ventricular Hypertrophy and Dysfunction Caused by Neonatal Hyperoxia Exposure in Rats. Hypertension 74(4): 843-853.
• 751 Mobius, M. A., et al. (2019). Oxygen Disrupts Human Fetal Lung Mesenchymal Cells. Implications for Bronchopulmonary Dysplasia. Am J Respir Cell Mol Biol 60(5): 592-600.
• 752 Monteiro, L. J., et al. (2019). Reduced FOXM1 expression limits trophoblast migration and angiogenesis and is associated with preeclampsia. Reproductive Sciences 26(5): 580-590.
• 753 Moriyama, M., et al. (2019). Adipose-derived stromal/stem cells improve epidermal homeostasis. Sci Rep 9(1): 18371.
• 754 Mount, S., et al. (2019). Physiologic expansion of human heart-derived cells enhances therapeutic repair of injured myocardium. Stem Cell Res Ther 10(1): 316.
• 755 Murinello, S., et al. (2019). miR-30a-5p inhibition promotes interaction of Fas(+) endothelial cells and FasL(+) microglia to decrease pathological neovascularization and promote physiological angiogenesis. Glia 67(2): 332-344.
• 756 Nakamura, S., et al. (2019). Nrf2 Activator RS9 Suppresses Pathological Ocular Angiogenesis and Hyperpermeability. Invest Ophthalmol Vis Sci 60(6): 1943-1952.
• 757 Nasyrov, E., et al. (2019). The neuronal oxygen-sensing pathway controls postnatal vascularization of the murine brain. FASEB J 33(11): 12812-12824.
• 758 Nikolic, I., et al. (2019). Bone Morphogenetic Protein 9 Is a Mechanistic Biomarker of Portopulmonary Hypertension. Am J Respir Crit Care Med 199(7): 891-902.
• 759 Ning, F., et al. (2019). Hypoxia enhances CD8(+) TC2 cell-dependent airway hyperresponsiveness and inflammation through hypoxia-inducible factor 1alpha. J Allergy Clin Immunol 143(6): 2026-2037 e2027.
• 760 Nonn, O., et al. (2019). Placental CX3CL1 is deregulated by angiotensin II and contributes to a pro-inflammatory trophoblast-monocyte interaction. International journal of molecular sciences 20(3): 641
• 761 Obradovic, H., et al. (2019). Improving stemness and functional features of mesenchymal stem cells from Wharton’s jelly of a human umbilical cord by mimicking the native, low oxygen stem cell niche. Placenta 82: 25-34.
• 762 Ock, S., et al. (2019). RANKL blockade suppresses pathological angiogenesis and vascular leakage in ischemic retinopathy. Biochem Biophys Res Commun 516(2): 350-356.
• 763 Oleaga, C., et al. (2019). A human in vitro platform for the evaluation of pharmacology strategies in cardiac ischemia. APL Bioeng 3(3): 036103.
• 764 O’Leary, C., et al. (2019). Involvement of TRPV1 and TRPV4 Channels in Retinal Angiogenesis. Invest Ophthalmol Vis Sci 60(10): 3297-3309.
• 765 O’Leary, O. E., et al. (2019). The vasoreparative potential of endothelial colony-forming cells in the ischemic retina is enhanced by cibinetide, a non-hematopoietic erythropoietin mimetic. Exp Eye Res 182: 144-155.
• 766 O’Neill, J., et al. (2019). Renal cortical oxygen tension is decreased following exposure to long-term but not short-term intermittent hypoxia in the rat. Am J Physiol Renal Physiol 316(4): F635-F645.
• 767 Pagé, M., et al. (2019). CD34 regulates the skeletal muscle response to hypoxia. Journal of Muscle Research and Cell Motility: 1-10
• 768 Patil, S. S., et al. (2019). Alda-1 attenuates hyperoxia-induced mitochondrial dysfunction in lung vascular endothelial cells. Aging (Albany NY) 11(12): 3909-3918.
• 769 Peeples, E. S., et al. (2019). Combined Treatment with Insulin-Like Growth Factor 1 and AMD3100 Improves Motor Outcome in a Murine Model of Neonatal Hypoxic-Ischemic Encephalopathy. Dev Neurosci 41(5-6): 255-262.
• 770 Peloquin, G. L., et al. (2019). SU5416 does not attenuate early RV angiogenesis in the murine chronic hypoxia PH model. Respir Res 20(1): 123.
• 771 Poletto Bonetto, J. H., et al. (2019). Impact of early life AT1 blockade on adult cardiac morpho-functional changes and the renin-angiotensin system in a model of neonatal high oxygen-induced cardiomyopathy. Eur J Pharmacol 860: 172585.
• 772 Porzionato, A., et al. (2019). Intratracheal administration of clinical-grade mesenchymal stem cell-derived extracellular vesicles reduces lung injury in a rat model of bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol 316(1): L6-L19.
• 773 Qian, X., et al. (2019). Respiratory hyperoxia reverses immunosuppression by regulating myeloid-derived suppressor cells and PD-L1 expression in a triple-negative breast cancer mouse model. Am J Cancer Res 9(3): 529-545.
• 774 Qiu, J., et al. (2019). delta-Opioid Receptor-Nrf-2-Mediated Inhibition of Inflammatory Cytokines in Neonatal Hypoxic-Ischemic Encephalopathy. Mol Neurobiol 56(7): 5229-5240.
• 775 Rafikov, R., et al. (2019). Inositol monophosphatase 1 as a novel interacting partner of RAGE in pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 316(3): L428-L444.
• 776 Rashid, J., et al. (2019). Inhaled combination of sildenafil and rosiglitazone improves pulmonary hemodynamics, cardiac function, and arterial remodeling. Am J Physiol Lung Cell Mol Physiol 316(1): L119-L130.
• 777 Rashid, J., et al. (2019). Translational Physiology: Inhaled combination of sildenafil and rosiglitazone improves pulmonary hemodynamics, cardiac function, and arterial remodeling. American Journal of Physiology-Lung Cellular and Molecular Physiology 316(1): L119.
• 778 Rempel, L. C. T., et al. (2019). Chronic exposure to hypoxia attenuates renal injury and innate immunity activation in the remnant kidney model. Am J Physiol Renal Physiol 317(5): F1285-F1292.
• 779 Ribon-Demars, A., et al. (2019). Protective roles of estradiol against vascular oxidative stress in ovariectomized female rats exposed to normoxia or intermittent hypoxia. Acta Physiol (Oxf) 225(2): e13159.
• 780 Romanowicz, J., et al. (2019). Treatment With Tetrahydrobiopterin Improves White Matter Maturation in a Mouse Model for Prenatal Hypoxia in Congenital Heart Disease. J Am Heart Assoc 8(15): e012711.
• 781Roque III, J., et al. (2019). Strained, Photoejecting Ru (II) Complexes that are Cytotoxic Under Hypoxic Conditions. Photochemistry and photobiology
• 782 Rudyk, O., et al. (2019). Oxidation of PKGIalpha mediates an endogenous adaptation to pulmonary hypertension. Proc Natl Acad Sci U S A 116(26): 13016-13025.
• 783 Ruyle, B. C., et al. (2019). The PVN enhances cardiorespiratory responses to acute hypoxia via input to the nTS. Am J Physiol Regul Integr Comp Physiol 317(6): R818-R833.
• 784 Sadler, K. E., et al. (2019). Gabapentin alleviates chronic spontaneous pain and acute hypoxia-related pain in a mouse model of sickle cell disease. Br J Haematol 187(2): 246-260.
• 785 Saforo, D., et al. (2019). Primary lung cancer samples cultured under microenvironment-mimetic conditions enrich for mesenchymal stem-like cells that promote metastasis. Sci Rep 9(1): 4177.
• 786 Salazar, C., et al. (2019). The OXPHOS supercomplex assembly factor HIG2A responds to changes in energetic metabolism and cell cycle. J Cell Physiol 234(10): 17405-17419.
• 787 Scheuer, T., et al. (2019). Transient Improvement of Cerebellar Oligodendroglial Development in a Neonatal Hyperoxia Model by PDGFA Treatment. Dev Neurobiol 79(3): 222-235.
• 788 Sharma, S., et al. (2019). Mitochondrial hypoxic stress induces widespread RNA editing by APOBEC3G in natural killer cells. Genome Biol 20(1): 37.
• 789 Shigemura, M., et al. (2019). Elevated CO2 regulates the Wnt signaling pathway in mammals, Drosophila melanogaster and Caenorhabditis elegans. Sci Rep 9(1): 18251.
• 790 Shults, N. V., et al. (2019). Ultrastructural Changes of the Right Ventricular Myocytes in Pulmonary Arterial Hypertension. J Am Heart Assoc 8(5): e011227.
• 791 Simning, D., et al. (2019). The combined effects of salinity, hypoxia, and oil exposure on survival and gene expression in developing sheepshead minnows, Cyprinodon variegatus. Aquat Toxicol 214: 105234.
• 792 Singh, C., et al. (2019). Serine and 1-carbon metabolism are required for HIF-mediated protection against retinopathy of prematurity. JCI Insight 4(14).
• 793 Solingapuram Sai, K. K., et al. (2019). Initial biological evaluations of (18)F-KS1, a novel ascorbate derivative to image oxidative stress in cancer. EJNMMI Res 9(1): 43.
• 794 Souza, G. M., et al. (2019). Pre-and post-inspiratory neurons change their firing properties in female rats exposed to chronic intermittent hypoxia. Neuroscience 406: 467-486.
• 795 Steele, A. N., et al. (2019). A Biocompatible Therapeutic Catheter-Deliverable Hydrogel for In Situ Tissue Engineering. Adv Healthc Mater 8(5): e1801147.
• 796 Sun, H., et al. (2019). ESM-1 promotes adhesion between monocytes and endothelial cells under intermittent hypoxia. J Cell Physiol 234(2): 1512-1521.
• 797 Swaminathan, G., et al. (2019). Hypoxia Stimulates Synthesis of Neutrophil Gelatinase-Associated Lipocalin in Aortic Valve Disease. Front Cardiovasc Med 6: 156.
• 798 Sweeney, N. W., et al. (2019). Hypoxia Suppresses High Fat Diet-Induced Steatosis And Development Of Hepatic Adenomas. Hypoxia (Auckl) 7: 53-63.
• 799 Tajiri, A., et al. (2019). Hyperoxia reduces salivary secretion by inducing oxidative stress in mice. Arch Oral Biol 98: 38-46.
• 800 Tan, Z., et al. (2019). Environmental stresses induce karyotypic instability in colorectal cancer cells. Mol Biol Cell 30(1): 42-55.
• 801 Tedesco, L., et al. (2019). von Hippel-Lindau mutants in renal cell carcinoma are regulated by increased expression of RSUME. Cell Death Dis 10(4): 266.
• 802 Tejero, R., et al. (2019). Gene signatures of quiescent glioblastoma cells reveal mesenchymal shift and interactions with niche microenvironment. EBioMedicine 42: 252-269.
• 803 Tiono, J., et al. (2019). Mouse genetic background impacts susceptibility to hyperoxia-driven perturbations to lung maturation. Pediatr Pulmonol 54(7): 1060-1077.
• 804 Tisch, N., et al. (2019). Caspase-8 modulates physiological and pathological angiogenesis during retina development. J Clin Invest 129(12): 5092-5107.
• 805 Tornabene, E., et al. (2019). Effects of oxygen-glucose deprivation (OGD) on barrier properties and mRNA transcript levels of selected marker proteins in brain endothelial cells/astrocyte co-cultures. PLOS ONE 14(8): e0221103.
• 806 Tozoni, S. S., et al. (2019). Uremia and Hypoxia Independently Induce Eryptosis and Erythrocyte Redox Imbalance. Cell Physiol Biochem 53: 794-804.
• 807 Tripathi, A., et al. (2019). Intermittent Hypoxia and Hypercapnia Reproducibly Change the Gut Microbiome and Metabolome across Rodent Model Systems. mSystems 4(2): e00058-00019.
• 808 Tsai, M.-J., et al. (2019). Attenuating spinal cord injury by conditioned medium from bone marrow mesenchymal stem cells. Journal of clinical medicine 8(1): 23
• 809 Vera, N., et al. (2019). Small Extracellular Vesicles Released from Ovarian Cancer Spheroids in Response to Cisplatin Promote the Pro-Tumorigenic Activity of Mesenchymal Stem Cells. Int J Mol Sci 20(20): 4972.
• 810 Vijayan, M., et al. (2019). Novel miRNA PC-5P-12969 in Ischemic Stroke. Mol Neurobiol 56(10): 6976-6985.
• 811 Wall, S. B., et al. (2019). Thioredoxin Reductase-1 Inhibition Augments Endogenous Glutathione-Dependent Antioxidant Responses in Experimental Bronchopulmonary Dysplasia. Oxid Med Cell Longev 2019: 7945983.
• 812 Wang, J., et al. (2019). Glucagon-like peptide-1 (GLP-1) mediates the protective effects of dipeptidyl peptidase IV inhibition on pulmonary hypertension. J Biomed Sci 26(1): 6.
• 813 Wang, Z., et al. (2019). Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 316(1): L216-L228.
• 814 Wedgwood, S., et al. (2019). The developing gut–lung axis: postnatal growth restriction, intestinal dysbiosis, and pulmonary hypertension in a rodent model. Pediatric Research: 1-8
• 815 Wei, Y., et al. (2019). Hypoxia-induced circular RNA has_circRNA_403658 promotes bladder cancer cell growth through activation of LDHA. Am J Transl Res 11(11): 6838-6849.
• 816 Weiner, G. A., et al. (2019). Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation. Nat Commun 10(1): 2477.
• 817 Wu, C., et al. (2019). Tangeretin protects human brain microvascular endothelial cells against oxygen-glucose deprivation-induced injury. J Cell Biochem 120(4): 4883-4891.
• 818 Wulftange, W. J., et al. (2019). Spatial control of oxygen delivery to three-dimensional cultures alters cancer cell growth and gene expression. J Cell Physiol 234(11): 20608-20622.
• 819 Xu, R., et al. (2019). The role of the XBP-1/AGR2 signaling pathway in the regulation of airway Mucin5ac hypersecretion under hypoxia. Exp Cell Res 382(1): 111442.
• 820 Xu, W., et al. (2019). TRAF1 Exacerbates Myocardial Ischemia Reperfusion Injury via ASK1-JNK/p38 Signaling. J Am Heart Assoc 8(21): e012575.
• 821 Xu, X., et al. (2019). Early Enzyme Replacement Therapy Improves Hearing and Immune Defects in Adenosine Deaminase Deficient-Mice. Front Immunol 10: 416.
• 822 Yang, F., et al. (2019). Leptin enhances glycolysis via OPA1-mediated mitochondrial fusion to promote mesenchymal stem cell survival. Int J Mol Med 44(1): 301-312.
• 823 Yang, L., et al. (2019). Creg in Hepatocytes Ameliorates Liver Ischemia/Reperfusion Injury in a TAK1-Dependent Manner in Mice. Hepatology 69(1): 294-313.
• 824 Yao, H., et al. (2019). Fatty Acid Oxidation Protects against Hyperoxia-induced Endothelial Cell Apoptosis and Lung Injury in Neonatal Mice. Am J Respir Cell Mol Biol 60(6): 667-677.
• 825 Yim, H. E., et al. (2019). Controlled Delivery of Stem Cell-Derived Trophic Factors Accelerates Kidney Repair After Renal Ischemia-Reperfusion Injury in Rats. Stem Cells Transl Med 8(9): 959-970.
• 826 Yoon, D. W., et al. (2019). Intermittent hypoxia promotes carcinogenesis in azoxymethane and dextran sodium sulfate-induced colon cancer model. Mol Carcinog 58(5): 654-665.
• 827 Yu, S., et al. (2019). Hypoxia-induced miR-191-C/EBPbeta signaling regulates cell proliferation and apoptosis of fibroblast-like synoviocytes from patients with rheumatoid arthritis. Arthritis Res Ther 21(1): 78.
• 828 Yuan, X., et al. (2019). Aggregation of human mesenchymal stem cells enhances survival and efficacy in stroke treatment. Cytotherapy 21(10): 1033-1048.
• 829 Zaitoun, I. S., et al. (2019). Bcl-2 Expression in Pericytes and Astrocytes Impacts Vascular Development and Homeostasis. Sci Rep 9(1): 9700.
• 830 Zambuto, S. G., et al. (2019). Response of neuroglia to hypoxia-induced oxidative stress using enzymatically crosslinked hydrogels. MRS Communications: 1-8
• 831 Zhang, D., et al. (2019). lncRNA HOTAIR Protects Myocardial Infarction Rat by Sponging miR-519d-3p. J Cardiovasc Transl Res 12(3): 171-183.
• 832 Zhang, F., et al. (2019). Radiosensitizing effects of Cyclocarya paliurus polysaccharide on hypoxic A549 and H520 human non-small cell lung carcinoma cells. Int J Mol Med 44(4): 1233-1242.
• 833 Zhang, J., et al. (2019). Curcumin improves perfusion recovery in experimental peripheral arterial disease by upregulating microRNA-93 expression. Exp Ther Med 17(1): 798-802.
• 834 Zhang, J., et al. (2019). The AAA + ATPase Thorase is neuroprotective against ischemic injury. J Cereb Blood Flow Metab 39(9): 1836-1848.
• 835 Zhang, Q. Y., et al. (2019). Neuroprotective Effect of SCM-198 through Stabilizing Endothelial Cell Function. Oxid Med Cell Longev 2019: 7850154.
• 836 Zhang, X., et al. (2019). Adiponectin Relieves Human Adult Cardiac Myocytes Injury Induced by Intermittent Hypoxia. Med Sci Monit 25: 786-793.
• 837 Zhao, S., et al. (2019). Placental growth factor gene silencing mitigates the epithelial‑to‑mesenchymal transition via the p38 MAPK pathway in rats with hyperoxia‑induced lung injury. Molecular medicine reports 20(6): 4867-4874.
• 838 Zheng, J., et al. (2019). Nrdp1 is involved in hippocampus apoptosis in cardiopulmonary bypass-induced cognitive dysfunction via the regulation of ErbB3 protein levels. International journal of molecular medicine 43(4): 1747-1757.
• 839 Zhou, F., et al. (2019). Prevascularized mesenchymal stem cell-sheets increase survival of random skin flaps in a nude mouse model. Am J Transl Res 11(3): 1403-1416.
• 840 Zhou, J., et al. (2019). USP4 deficiency exacerbates hepatic ischaemia/reperfusion injury via TAK1 signalling. Clin Sci (Lond) 133(2): 335-349.
• 841 Zhou, Y., et al. (2019). MicroRNA-221 Is Cardioprotective and Anti-fibrotic in a Rat Model of Myocardial Infarction. Mol Ther Nucleic Acids 17: 185-197.
• 842 Zhu, X. and X. Lu (2019). MiR-423-5p inhibition alleviates cardiomyocyte apoptosis and mitochondrial dysfunction caused by hypoxia/reoxygenation through activation of the wnt/beta-catenin signaling pathway via targeting MYBL2. J Cell Physiol 234(12): 22034-22043.
• 843 Zoccal, D. B., et al. (2019). Centrally acting adrenomedullin in the long-term potentiation of sympathetic vasoconstrictor activity induced by intermittent hypoxia in rats. Exp Physiol 104(9): 1371-1383.
• 844 Abid, S., et al. (2018). New Nitric Oxide Donor NCX 1443: Therapeutic Effects on Pulmonary Hypertension in the SAD Mouse Model of Sickle Cell Disease. J Cardiovasc Pharmacol 71(5): 283-292.
• 845 Abu Eid, S., et al. (2018). Life Under Hypoxia Lowers Blood Glucose Independently of Effects on Appetite and Body Weight in Mice. Front Endocrinol (Lausanne) 9: 490.
• 846 Ahmed, H. A., et al. (2018). RAS modulation prevents progressive cognitive impairment after experimental stroke: a randomized, blinded preclinical trial. J Neuroinflammation 15(1): 229.
• 847 Al-Ahmad, A. J., et al. (2018). Hyaluronan impairs the barrier integrity of brain microvascular endothelial cell through a CD44-dependent pathway. Journal of Cerebral Blood Flow & Metabolism: 0271678X18767748
• 848 Al-Anazi, A., et al. (2018). Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression. Data Brief 21: 2395-2397.
• 849 Al-Anazi, A., et al. (2018). Intracellular calcium and NF-kB regulate hypoxia-induced leptin, VEGF, IL-6 and adiponectin secretion in human adipocytes. Life Sci 212: 275-284.
• 850 Alencar, A. K. N., et al. (2018). Human Mesenchymal Stem Cell Therapy Reverses Su5416/Hypoxia-Induced Pulmonary Arterial Hypertension in Mice. Front Pharmacol 9: 1395.
• 851 Allawzi, A. M., et al. (2018). Activation of anoctamin-1 limits pulmonary endothelial cell proliferation via p38–mitogen-activated protein kinase–dependent apoptosis. American Journal of Respiratory Cell and Molecular Biology 58(5): 658-667
• 852 Allwood, M. A., et al. (2018). Moderate and severe hypoxia elicit divergent effects on cardiovascular function and physiological rhythms. J Physiol 596(15): 3391-3410.
• 853 Anderson, D. E., et al. (2018). Physioxia Promotes the Articular Chondrocyte-Like Phenotype in Human Chondroprogenitor-Derived Self-Organized Tissue. Tissue Eng Part A 24(3-4): 264-274.
• 854 Augstein, P., et al. (2018). Characterization of the Human Pancreas Side Population as a Potential Reservoir of Adult Stem Cells. Pancreas 47(1): 25-34.
• 855 Avezov, K., et al. (2018). Intermittent Hypoxia and Unsaturated Aldehydes: Effects on Oral Epithelial Wound Healing. Adv Exp Med Biol 1023: 47-54.
• 856 Bargiela, D., et al. (2018). Mitochondria and Hypoxia: Metabolic Crosstalk in Cell-Fate Decisions. Trends Endocrinol Metab 29(4): 249-259.
• 857Barnes, J. and R. C. Upstill-Goddard (2018). The denitrification paradox: The role of O2 in sediment N2O production. Estuarine, Coastal and Shelf Science 200: 270-276
• 858 Barreto Ortiz, S., et al. (2018). Opsin 3 and 4 mediate light-induced pulmonary vasorelaxation that is potentiated by G protein-coupled receptor kinase 2 inhibition. Am J Physiol Lung Cell Mol Physiol 314(1): L93-L106.
• 859 Becker, S., et al. (2018). Targeted Knockdown of Overexpressed VEGFA or VEGF164 in Muller cells maintains retinal function by triggering different signaling mechanisms. Sci Rep 8(1): 2003.
• 860 Beharry, K. D., et al. (2018). Human retinal endothelial cells and astrocytes cultured on 3-D scaffolds for ocular drug discovery and development. Prostaglandins Other Lipid Mediat 134: 93-107.
• 861 Beharry, K. D., et al. (2018). Impact of Chronic Neonatal Intermittent Hypoxia on Severity of Retinal Damage in a Rat Model of Oxygen-Induced Retinopathy. J Nat Sci 4(3).
• 862 Beharry, K. D., et al. (2018). Intermittent hypoxia alters dose dependent caffeine effects on renal prostanoids and receptors in neonatal rats. Prostaglandins Other Lipid Mediat 134: 57-65.
• 863 Beharry, K. D., et al. (2018). Oxygen-induced retinopathy from recurrent intermittent hypoxia is not dependent on resolution with room air or oxygen, in neonatal rats. International journal of molecular sciences 19(5): 1337
• 864 Benyamine, A., et al. (2018). BTN3A is a prognosis marker and a promising target for Vγ9Vδ2 T cells based-immunotherapy in pancreatic ductal adenocarcinoma (PDAC). Oncoimmunology 7(1): e1372080
• 865 Bergholt, N. L., et al. (2018). Surface chemistry, substrate, and topography guide the behavior of human articular chondrocytes cultured in vitro. J Biomed Mater Res A 106(11): 2805-2816.
• 866 Bernstock, J. D., et al. (2018). Quantitative high-throughput screening identifies cytoprotective molecules that enhance SUMO conjugation via the inhibition of SUMO-specific protease (SENP)2. FASEB J 32(3): 1677-1691.
• 867 Bik-Multanowski, M., et al. (2018). Hyperoxia induces epigenetic changes in newborn mice lungs. Free Radic Biol Med 121: 51-56.
• 868 Binder, U., et al. (2018). Generation of a Mucor circinelloides reporter strain—a promising new tool to study antifungal drug efficacy and mucormycosis. Genes 9(12): 613
• 869 Bordt, E. A. (2018). The importance of controlling in vitro oxygen tension to accurately model in vivo neurophysiology. Neurotoxicology 66: 213-220.
• 870 Boregowda, S. V., et al. (2018). Basal p53 expression is indispensable for mesenchymal stem cell integrity. Cell Death & Differentiation 25(4): 679-692
• 871 Bourdieu, A., et al. (2018). Steady state peripheral blood provides cells with functional and metabolic characteristics of real hematopoietic stem cells. J Cell Physiol 233(1): 338-349.
• 872 Burman, A., et al. (2018). Localized hypoxia links ER stress to lung fibrosis through induction of C/EBP homologous protein. JCI Insight 3(16)
• 873 Burnight, E. R., et al. (2018). CRISPR-Cas9 genome engineering: Treating inherited retinal degeneration. Prog Retin Eye Res 65: 28-49.
• 874 Burnight, E. R., et al. (2018). CRISPR-Cas9-Mediated Correction of the 1.02 kb Common Deletion in CLN3 in Induced Pluripotent Stem Cells from Patients with Batten Disease. CRISPR J 1(1): 75-87.
• 875 Burr, S., et al. (2018). Oxygen gradients can determine epigenetic asymmetry and cellular differentiation via differential regulation of Tet activity in embryonic stem cells. Nucleic Acids Res 46(3): 1210-1226.
• 876 Cahill, L. S., et al. (2018). Feto- and utero-placental vascular adaptations to chronic maternal hypoxia in the mouse. J Physiol 596(15): 3285-3297.
• 877 Chang, C. W., et al. (2018). Trophoblast lineage specification, differentiation and their regulation by oxygen tension. J Endocrinol 236(1): R43-R56.
• 878 Chang, J. L., et al. (2018). Intrauterine Growth Restriction and Hyperoxia as a Cause of White Matter Injury. Developmental neuroscience: 1-14
• 879 Chang, W.-T., et al. (2018). MicroRNA-21 is Associated with the Severity of Right Ventricular Dysfunction in Patients with Hypoxia-Induced Pulmonary Hypertension. Acta Cardiologica Sinica 34(6): 511
• 880 Chao, C. M., et al. (2018). Neonatal exposure to hyperoxia leads to persistent disturbances in pulmonary histone signatures associated with NOS3 and STAT3 in a mouse model. Clin Epigenetics 10(1): 37.
• 881Chaqour, J., et al. (2018). Abscisic acid: an antiangiogenic phytohormone that modulates the phenotypical plasticity of endothelial cells and macrophages. J Cell Sci: jcs. 210492
• 882 Chau, M. J., et al. (2018). Delayed and repeated intranasal delivery of bone marrow stromal cells increases regeneration and functional recovery after ischemic stroke in mice. BMC Neurosci 19(1): 20.
• 883 Chaubey, S., et al. (2018). Early gestational mesenchymal stem cell secretome attenuates experimental bronchopulmonary dysplasia in part via exosome-associated factor TSG-6. Stem Cell Res Ther 9(1): 173.
• 884 Chaudhary, K. R., et al. (2018). Efficacy of treprostinil in the SU5416-hypoxia model of severe pulmonary arterial hypertension: haemodynamic benefits are not associated with improvements in arterial remodelling. Br J Pharmacol 175(20): 3976-3989.
• 885 Chen, C.-M., et al. (2018). Tn (N-acetyl-d-galactosamine-O-serine/threonine) immunization protects against hyperoxia-induced lung injury in adult mice through inhibition of the nuclear factor kappa B activity. International immunopharmacology 59: 261-268
• 886 Chen, J. E., et al. (2018). Hypoxia activates enhanced invasive potential and endogenous hyaluronic acid production by glioblastoma cells. Biomater Sci 6(4): 854-862.
• 887 Chen, L., et al. (2018). MicroRNA-133a impairs perfusion recovery after hindlimb ischemia in diabetic mice. Biosci Rep 38(4).
• 888 Cheon, I. S., et al. (2018). Neonatal hyperoxia promotes asthma-like features through IL-33-dependent ILC2 responses. J Allergy Clin Immunol 142(4): 1100-1112.
• 889 Chihanga, T., et al. (2018). NMR-based urine metabolic profiling and immunohistochemistry analysis of nephron changes in a mouse model of hypoxia-induced acute kidney injury. Am J Physiol Renal Physiol 315(4): F1159-F1173.
• 890 Cho, B., et al. (2018). Systemic control of immune cell development by integrated carbon dioxide and hypoxia chemosensation in Drosophila. Nat Commun 9(1): 2679.
• 891 Christou, H., et al. (2018). Impaired pulmonary arterial vasoconstriction and nitric oxide–Mediated relaxation underlie severe pulmonary hypertension in the sugen-Hypoxia rat model. Journal of Pharmacology and Experimental Therapeutics 364(2): 258-274
• 892 Coelho, N. R., et al. (2018). Cysteine Oxidative Dynamics Underlies Hypertension and Kidney Dysfunction Induced by Chronic Intermittent Hypoxia. Adv Exp Med Biol 1071: 83-88.
• 893 Crassini, K., et al. (2018). The dual inhibitor of the phosphoinositol-3 and PIM kinases, IBL-202, is effective against chronic lymphocytic leukaemia cells under conditions that mimic the hypoxic tumour microenvironment. Br J Haematol 182(5): 654-669.
• 894 Dai, J., et al. (2018). Alpha-enolase regulates the malignant phenotype of pulmonary artery smooth muscle cells via the AMPK-Akt pathway. Nat Commun 9(1): 3850.
• 895 Dai, J., et al. (2018). Smooth muscle cell-specific FoxM1 controls hypoxia-induced pulmonary hypertension. Cell Signal 51: 119-129.
• 896 Dai, Z., et al. (2018). Therapeutic Targeting of Vascular Remodeling and Right Heart Failure in Pulmonary Arterial Hypertension with a HIF-2alpha Inhibitor. Am J Respir Crit Care Med 198(11): 1423-1434.
• 897 Das, M., et al. (2018). JNK2 regulates vascular remodeling in pulmonary hypertension. Pulm Circ 8(3): 2045894018778156.
• 898 de Oliveira, R. W., et al. (2018). Chronic intermittent hypoxia induces changes on the expression and activity of neprilysin (EC 3.4. 24.16) in the brain of rats. Neuroscience Letters
• 899 de Theije, C. C., et al. (2018). Glucocorticoid Receptor Signaling Impairs Protein Turnover Regulation in Hypoxia-Induced Muscle Atrophy in Male Mice. Endocrinology 159(1): 519-534.
• 900 de Theije, C. C., et al. (2018). Hypoxia impairs adaptation of skeletal muscle protein turnover- and AMPK signaling during fasting-induced muscle atrophy. PLOS ONE 13(9): e0203630.
• 901 Devlin, M. J., et al. (2018). Differential effects of high fat diet and diet-induced obesity on skeletal acquisition in female C57BL/6J vs. FVB/NJ Mice. Bone Rep 8: 204-214.
• 902 Ding, H.-G., et al. (2018). Hypercapnia induces IL-1β overproduction via activation of NLRP3 inflammasome: implication in cognitive impairment in hypoxemic adult rats. Journal of neuroinflammation 15(1): 4.
• 903 Dorayappan, K. D. P., et al. (2018). Hypoxia-induced exosomes contribute to a more aggressive and chemoresistant ovarian cancer phenotype: a novel mechanism linking STAT3/Rab proteins. Oncogene 37(28): 3806-3821.
• 904 Dunn, R., et al. (2018). Divergent effects of levetiracetam and tiagabine against spontaneous seizures in adult rats following neonatal hypoxia. Epilepsy Res 140: 1-7.
• 905 Dvoriantchikova, G., et al. (2018). Pannexin 1 sustains the electrophysiological responsiveness of retinal ganglion cells. Sci Rep 8(1): 5797.
• 906 Elamaa, H., et al. (2018). Angiopoietin-4-dependent venous maturation and fluid drainage in the peripheral retina. eLife 7: e37776.
• 907 Elliot-Portal, E., et al. (2018). Brain-derived erythropoietin protects from intermittent hypoxia-induced cardiorespiratory dysfunction and oxidative stress in mice. Sleep 41(7).
• 908 Elshaer, S. L. and A. B. El-Remessy (2018). Deletion of p75 NTR prevents vaso-obliteration and retinal neovascularization via activation of Trk-A receptor in ischemic retinopathy model. Scientific Reports 8(1): 12490.
• 909 Fan, W. L., et al. (2018). Transplantation of hypoxic preconditioned neural stem cells benefits functional recovery via enhancing neurotrophic secretion after spinal cord injury in rats. J Cell Biochem 119(6): 4339-4351.
• 910 Feng, Q., et al. (2018). Hypoxia-specific therapeutic agents delivery nanotheranostics: A sequential strategy for ultrasound mediated on-demand tritherapies and imaging of cancer. J Control Release 275: 192-200.
• 911 Flor, K. C., et al. (2018). Short-term sustained hypoxia elevates basal and hypoxia-induced ventilation but not the carotid body chemoreceptor activity in rats. Frontiers in physiology 9: 134
• 912 Flores-Santin, J., et al. (2018). Hematology from embryo to adult in the bobwhite quail (Colinus virginianus): Differential effects in the adult of clutch, sex and hypoxic incubation. Comp Biochem Physiol A Mol Integr Physiol 218: 24-34.
• 913 Foxler, D. E., et al. (2018). A HIF-LIMD1 negative feedback mechanism mitigates the pro-tumorigenic effects of hypoxia. EMBO Mol Med 10(8).
• 914 Frille, A., et al. (2018). No erythropoietin-induced growth is observed in non-small cell lung cancer cells. International journal of oncology 52(2): 518-526
• 915 Gagner, J. P., et al. (2018). Induction and Assessment of Hypoxia in Glioblastoma Cells In Vitro. Methods Mol Biol 1741: 111-123.
• 916 Gallo, S., et al. (2018). Upregulation of the alternative splicing factor NOVA2 in colorectal cancer vasculature. Onco Targets Ther 11: 6049-6056.
• 917 Gao, J., et al. (2018). The midline axon crossing decision is regulated through an activity-dependent mechanism by the NMDA receptor. eneuro 5(2)
• 918 Gauster, M., et al. (2018). Downregulation of p53 drives autophagy during human trophoblast differentiation. Cell Mol Life Sci 75(10): 1839-1855.
• 919 Gazdhar, A., et al. (2018). Alpha-Klotho Enrichment in Induced Pluripotent Stem Cell Secretome Contributes to Antioxidative Protection in Acute Lung Injury. Stem Cells 36(4): 616-625.
• 920 Gerri, C., et al. (2018). Hif-1α and Hif-2α regulate hemogenic endothelium and hematopoietic stem cell formation in zebrafish. Blood 131(9): 963-973
• 921 Girard-Bock, C., et al. (2018). Endothelial colony-forming cell therapy for heart morphological changes after neonatal high oxygen exposure in rats, a model of complications of prematurity. Physiol Rep 6(22): e13922.
• 922 Gong, L., et al. (2018). Knockdown of long non-coding RNA MEG3 protects H9c2 cells from hypoxia-induced injury by targeting microRNA-183. J Cell Biochem 119(2): 1429-1440.
• 923 Gong, T., et al. (2018). Knockdown of KLF5 suppresses hypoxia-induced resistance to cisplatin in NSCLC cells by regulating HIF-1α-dependent glycolysis through inactivation of the PI3K/Akt/mTOR pathway. J Transl Med 16(1): 164
• 924 Grissom, N. M., et al. (2018). Male-specific deficits in natural reward learning in a mouse model of neurodevelopmental disorders. Mol Psychiatry 23(3): 544-555.
• 925 Gu, J. M., et al. (2018). Blockade of placental growth factor reduces vaso-occlusive complications in murine models of sickle cell disease. Exp Hematol 60: 73-82 e73.
• 926 Halder, S. K., et al. (2018). Chronic mild hypoxia increases expression of laminins 111 and 411 and the laminin receptor alpha6beta1 integrin at the blood-brain barrier. Brain Res 1700: 78-85.
• 927 Halder, S. K., et al. (2018). Chronic mild hypoxia promotes profound vascular remodeling in spinal cord blood vessels, preferentially in white matter, via an α5β1 integrin-mediated mechanism. Angiogenesis: 1-16
• 928 Halder, S. K., et al. (2018). Hypoxic pre-conditioning suppresses experimental autoimmune encephalomyelitis by modifying multiple properties of blood vessels. Acta Neuropathol Commun 6(1): 86.
• 929 Han, Q., et al. (2018). Haemin attenuates intermittent hypoxia-induced cardiac injury via inhibiting mitochondrial fission. J Cell Mol Med 22(5): 2717-2726.
• 930 Han, S., et al. (2018). Temporal blood flow changes measured by diffuse correlation tomography predict murine femoral graft healing. PLOS ONE 13(5): e0197031.
• 931 Harris, E. M., et al. (2018). Preclinical Evaluation of Discorhabdins in Antiangiogenic and Antitumor Models. Mar Drugs 16(7): 241.
• 932 Harvey, A. J., et al. (2018). Physiological oxygen culture reveals retention of metabolic memory in human induced pluripotent stem cells. PLOS ONE 13(3): e0193949.
• 933 Heo, J. H., et al. (2018). Combined Treatment with Low-Level Laser and rhBMP-2 Promotes Differentiation and Mineralization of Osteoblastic Cells under Hypoxic Stress. Tissue Eng Regen Med 15(6): 793-801.
• 934 Herz, J., et al. (2018). Interaction between hypothermia and delayed mesenchymal stem cell therapy in neonatal hypoxic-ischemic brain injury. Brain Behav Immun 70: 118-130.
• 935 Herz, J., et al. (2018). Peripheral T Cell Depletion by FTY720 Exacerbates Hypoxic-Ischemic Brain Injury in Neonatal Mice. Front Immunol 9: 1696.
• 936 Heuslein, J. L., et al. (2018). Exposure of endothelium to biomimetic flow waveforms yields identification of miR-199a-5p as a potent regulator of arteriogenesis. Molecular Therapy-Nucleic Acids 12: 829-844
• 937 Heuslein, J. L., et al. (2018). MicroRNA-146a Regulates Perfusion Recovery in Response to Arterial Occlusion via Arteriogenesis. Front Bioeng Biotechnol 6: 1.
• 938 Hu, H., et al. (2018). Interleukin-22 receptor 1 upregulation and activation in hypoxic endothelial cells improves perfusion recovery in experimental peripheral arterial disease. Biochem Biophys Res Commun 505(1): 60-66.
• 939 Iizuka, N., et al. (2018). Anti-angiogenic effects of valproic acid in a mouse model of oxygen-induced retinopathy. J Pharmacol Sci 138(3): 203-208.
• 940Ikeda, K. T., et al. (2018). Hypoxia-Induced Pulmonary Hypertension in Different Mouse Strains-Relation to Transcriptome. American Journal of Respiratory Cell and Molecular Biology(ja)
• 941 Jaber, S. M., et al. (2018). Sex differences in the mitochondrial bioenergetics of astrocytes but not microglia at a physiologically relevant brain oxygen tension. Neurochem Int 117: 82-90.
• 942 Jankov, R. P., et al. (2018). Sodium nitrite augments lung S-nitrosylation and reverses chronic hypoxic pulmonary hypertension in juvenile rats. Am J Physiol Lung Cell Mol Physiol 315(5): L742-L751.
• 943 Jiang, Y., et al. (2018). Two-pore channels mediated receptor-operated Ca(2+) entry in pulmonary artery smooth muscle cells in response to hypoxia. Int J Biochem Cell Biol 97: 28-35.
• 944 Jochmans-Lemoine, A., et al. (2018). Divergent mitochondrial antioxidant activities and lung alveolar architecture in the lungs of rats and mice at high altitude. Frontiers in physiology 9: 311
• 945 Juch, H., et al. (2018). Dendritic polyglycerol nanoparticles show charge dependent bio-distribution in early human placental explants and reduce hCG secretion. Nanotoxicology 12(2): 90-103.
• 946 Kadle, R. L., et al. (2018). Microenvironmental cues enhance mesenchymal stem cell-mediated immunomodulation and regulatory T-cell expansion. PLOS ONE 13(3): e0193178.
• 947 Kannler, M., et al. (2018). TRPA1 channels: expression in non-neuronal murine lung tissues and dispensability for hyperoxia-induced alveolar epithelial hyperplasia. Pflugers Arch 470(8): 1231-1241.
• 948 Kim, D. S., et al. (2018). Carbon Monoxide Inhibits Islet Apoptosis via Induction of Autophagy. Antioxid Redox Signal 28(14): 1309-1322.
• 949 Kim, S. W., et al. (2018). Normobaric hyperoxia inhibits the progression of lung cancer by inducing apoptosis. Exp Biol Med (Maywood) 243(9): 739-748.
• 950 Klier, M., et al. (2018). Enzymatic activity is not required for phospholipase D mediated TNF-α regulation and myocardial healing. Frontiers in physiology 9: 1698
• 951 Klinke, A., et al. (2018). Myeloperoxidase aggravates pulmonary arterial hypertension by activation of vascular Rho-kinase. JCI Insight 3(11).
• 952Koch, A., et al. (2018). Ex-vivo-Lungenperfusion. Zeitschrift für Herz-, Thorax-und Gefäßchirurgie 32(4): 325-330
• 953 Kolb, A. L., et al. (2018). Exogenous Gene Transmission of Isocitrate Dehydrogenase 2 Mimics Ischemic Preconditioning Protection. J Am Soc Nephrol 29(4): 1154-1164.
• 954 Kosaku, K., et al. (2018). Long-Term Hypoxic Tolerance in Murine Cornea. High Alt Med Biol 19(1): 35-41.
• 955 Kossatz, E., et al. (2018). Octadecylpropyl Sulfamide Reduces Neurodegeneration and Restores the Memory Deficits Induced by Hypoxia-Ischemia in Mice. Front Pharmacol 9: 376.
• 956 Kosuru, R., et al. (2018). AMPK Contributes to Cardioprotective Effects of Pterostilbene Against Myocardial Ischemia- Reperfusion Injury in Diabetic Rats by Suppressing Cardiac Oxidative Stress and Apoptosis. Cell Physiol Biochem 46(4): 1381-1397.
• 957 Kulkarni, S., et al. (2018). A large-scale RNAi screen identifies SGK1 as a key survival kinase for GBM stem cells. Molecular Cancer Research 16(1): 103-114
• 958 Kwon, M. Y., et al. (2018). NOD2 deficiency exacerbates hypoxia-induced pulmonary hypertension and enhances pulmonary vascular smooth muscle cell proliferation. Oncotarget 9(16): 12671-12681.
• 959 Lalowski, M. M., et al. (2018). Characterizing the key metabolic pathways of the neonatal mouse heart using a quantitative combinatorial omics approach. Frontiers in physiology 9: 365
• 960 Lambertini, E., et al. (2018). Hypoxia Preconditioning of Human MSCs: a Direct Evidence of HIF-1alpha and Collagen Type XV Correlation. Cell Physiol Biochem 51(5): 2237-2249.
• 961 Lamy, S., et al. (2018). Antiproliferative efficacy of elderberries and elderflowers (Sambucus canadensis) on glioma and brain endothelial cells under normoxic and hypoxic conditions. Journal of Functional Foods 40: 164-179.
• 962 Landucci, E., et al. (2018). Bicuculline Reverts the Neuroprotective Effects of Meloxicam in an Oxygen and Glucose Deprivation (OGD) Model of Organotypic Hippocampal Slice Cultures. Neuroscience 386: 68-78.
• 963 Landucci, E., et al. (2018). Neuroprotective effects of topiramate and memantine in combination with hypothermia in hypoxic-ischemic brain injury in vitro and in vivo. Neurosci Lett 668: 103-107.
• 964 Larouche, O., et al. (2018). Real-life Lernaean Hydras: a practical activity about the effects of oxygen concentration on regenerative capabilities of planarians. Journal of Biological Education 54(1): 98-107.
• 965 Lee, H. Y., et al. (2018). Combination of carboplatin and intermittent normobaric hyperoxia synergistically suppresses benzo[a]pyrene-induced lung cancer. Korean J Intern Med 33(3): 541-551.
• 966 Lee, M. Y. K., et al. (2018). Low but not high frequency of intermittent hypoxia suppresses endothelium-dependent, oxidative stress-mediated contractions in carotid arteries of obese mice. J Appl Physiol (1985) 125(5): 1384-1395.
• 967 Leiton, C. V., et al. (2018). Astrocyte HIF-2alpha supports learning in a passive avoidance paradigm under hypoxic stress. Hypoxia (Auckl) 6: 35-56.
• 968 Li, C., et al. (2018). AMPK promotes survival and adipogenesis of ischemia-challenged ADSCs in an autophagy-dependent manner. Biochim Biophys Acta Mol Cell Biol Lipids 1863(12): 1498-1510.
• 969 Li, M., et al. (2018). Alda-1 Ameliorates Liver Ischemia-Reperfusion Injury by Activating Aldehyde Dehydrogenase 2 and Enhancing Autophagy in Mice. J Immunol Res 2018: 9807139.
• 970 Li, R., et al. (2018). Autophagy activation and the mechanism of retinal microvascular endothelial cells in hypoxia. Int J Ophthalmol 11(4): 567-574.
• 971 Li, R., et al. (2018). Manipulation of autophagy: a novelly potential therapeutic strategy for retinal neovascularization. BMC Ophthalmol 18(1): 110.
• 972 Li, R., et al. (2018). Pdgfra marks a cellular lineage with distinct contributions to myofibroblasts in lung maturation and injury response. eLife 7: e36865.
• 973 Lien, C. F., et al. (2018). Intermittent hypoxia-generated ROS contributes to intracellular zinc regulation that limits ischemia/reperfusion injury in adult rat cardiomyocyte. J Mol Cell Cardiol 118: 122-132.
• 974 Lim, R., et al. (2018). First-In-Human Administration of Allogeneic Amnion Cells in Premature Infants With Bronchopulmonary Dysplasia: A Safety Study. Stem Cells Transl Med 7(9): 628-635.
• 975 Lin, Y., et al. (2018). SIRT1 Deletion Impairs Retinal Endothelial Cell Migration Through Downregulation of VEGF-A/VEGFR-2 and MMP14. Investigative Ophthalmology & Visual Science 59(13): 5431-5440
• 976Lippe, E. M. O. (2018). Angiogenic responses in the pregnant mouse uterus under uNK cell deletion and hypoxia. Brazilian Journal of Biological Sciences 5(9): 13-24
• 977 Liu, F., et al. (2018). The role of NF-κB-mediated JNK pathway in cognitive impairment in a rat model of sleep apnea. Journal of thoracic disease 10(12): 6921
• 978 Liu, J., et al. (2018). IL-33 Initiates Vascular Remodelling in Hypoxic Pulmonary Hypertension by up-Regulating HIF-1alpha and VEGF Expression in Vascular Endothelial Cells. EBioMedicine 33: 196-210.
• 979 Liu, K. X., et al. (2018). Detection and analysis of apoptosis- and autophagy-related miRNAs of mouse vascular endothelial cells in chronic intermittent hypoxia model. Life Sci 193: 194-199.
• 980 Liu, Y., et al. (2018). AMPA Receptor-Dependent Glutamatergic Signaling is Present in the Carotid Chemoreceptor. Neuroscience 382: 59-68.
• 981 Lo Re, O., et al. (2018). Histone variant macroH2A1 rewires carbohydrate and lipid metabolism of hepatocellular carcinoma cells towards cancer stem cells. Epigenetics 13(8): 829-845.
• 982 Lu, Z., et al. (2018). A role for heat shock factor 1 in hypercapnia-induced inhibition of inflammatory cytokine expression. FASEB J 32(7): 3614-3622.
• 983 Lucking, E. F., et al. (2018). Chronic intermittent hypoxia disrupts cardiorespiratory homeostasis and gut microbiota composition in adult male guinea-pigs. EBioMedicine 38: 191-205.
• 984 Luo, Y., et al. (2018). β‑catenin nuclear translocation induced by HIF‑1α overexpression leads to the radioresistance of prostate cancer. International journal of oncology
• 985 Luther, K. M., et al. (2018). Exosomal miR-21a-5p mediates cardioprotection by mesenchymal stem cells. J Mol Cell Cardiol 119: 125-137.
• 986 Ma, L., et al. (2018). Effect of Allicin against Ischemia/Hypoxia-Induced H9c2 Myoblast Apoptosis via eNOS/NO Pathway-Mediated Antioxidant Activity. Evid Based Complement Alternat Med 2018: 3207973.
• 987 MacLauchlan, S. C., et al. (2018). HIF-1alpha represses the expression of the angiogenesis inhibitor thrombospondin-2. Matrix Biol 65: 45-58.
• 988 McDonald, C. A., et al. (2018). Effects of umbilical cord blood cells, and subtypes, to reduce neuroinflammation following perinatal hypoxic-ischemic brain injury. J Neuroinflammation 15(1): 47.
• 989 McIntyre, L. A., et al. (2018). Cellular Immunotherapy for Septic Shock. A Phase I Clinical Trial. Am J Respir Crit Care Med 197(3): 337-347.
• 990 Merfeld-Clauss, S., et al. (2018). Hypoxia-induced activin A diminishes endothelial cell vasculogenic activity. J Cell Mol Med 22(1): 173-184.
• 991 Mertens, T. C. J., et al. (2018). Switching-Off Adora2b in Vascular Smooth Muscle Cells Halts the Development of Pulmonary Hypertension. Front Physiol 9: 555.
• 992 Moriyama, H., et al. (2018). Notch Signaling Enhances Stemness by Regulating Metabolic Pathways Through Modifying p53, NF-kappaB, and HIF-1alpha. Stem Cells Dev 27(13): 935-947.
• 993 Moya, A., et al. (2018). Human Mesenchymal Stem Cell Failure to Adapt to Glucose Shortage and Rapidly use Intracellular Energy Reserves through Glycolysis Explains Poor Cell Survival After Implantation. Stem Cells
• 994 Moya, A., et al. (2018). Osteogenic potential of adipogenic predifferentiated human bone marrow-derived multipotent stromal cells for bone tissue-engineering. J Tissue Eng Regen Med 12(3): e1511-e1524.
• 995 Nair, D., et al. (2018). Cognitive Deficits Are Attenuated in Neuroglobin Overexpressing Mice Exposed to a Model of Obstructive Sleep Apnea. Front Neurol 9: 426.
• 996 Nair, S., et al. (2018). Human placental exosomes in gestational diabetes mellitus carry a specific set of miRNAs associated with skeletal muscle insulin sensitivity. Clin Sci (Lond) 132(22): 2451-2467.
• 997 Narala, V. R., et al. (2018). Akap1 genetic deletion increases the severity of hyperoxia-induced acute lung injury in mice. Am J Physiol Lung Cell Mol Physiol 314(5): L860-L870.
• 998 Ng, K. P., et al. (2018). The arginase inhibitor Nomega-hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target. PLOS ONE 13(10): e0205254.
• 999 Nguyen, H. L., et al. (2018). Hypoxic postconditioning enhances functional recovery following endothelin-1 induced middle cerebral artery occlusion in conscious rats. Exp Neurol 306: 177-189.
• 1000 Nguyen, V., et al. (2018). Sonic Hedgehog Agonist Protects Against Complex Neonatal Cerebellar Injury. Cerebellum 17(2): 213-227.
• 1001 Nyp, M. F., et al. (2018). Lung epithelial-specific TRIP-1 overexpression maintains epithelial integrity during hyperoxia exposure. Physiol Rep 6(5).
• 1002 Nzou, G., et al. (2018). Human Cortex Spheroid with a Functional Blood Brain Barrier for High-Throughput Neurotoxicity Screening and Disease Modeling. Sci Rep 8(1): 7413.
• 1003 Oakley, R. H., et al. (2018). Muscle-specific regulation of right ventricular transcriptional responses to chronic hypoxia-induced hypertrophy by the muscle ring finger-1 (MuRF1) ubiquitin ligase in mice. BMC Med Genet 19(1): 175.
• 1004 O’Kane, D., et al. (2018). Zinc preconditioning protects against renal ischaemia reperfusion injury in a preclinical sheep large animal model. Biometals 31(5): 821-834.
• 1005 Panigrahi, G. K., et al. (2018). Hypoxia-induced exosome secretion promotes survival of African-American and Caucasian prostate cancer cells. Sci Rep 8(1): 3853.
• 1006 Peng, Y. and K. Hu (2018). Effect of garlic on rats with chronic intermittent hypoxia combined with diabetes mellitus. Mol Med Rep 17(4): 6174-6184.
• 1007 Perim, R. R., et al. (2018). Previous exposure to chronic intermittent hypoxia blunts the development of one-kidney, one-clip hypertension in rats. Exp Physiol 103(4): 473-482.
• 1008 Phan, T. G., et al. (2018). Phase 1 Trial of Amnion Cell Therapy for Ischemic Stroke. Front Neurol 9: 198.
• 1009 Piuzzi, N. S., et al. (2018). Intra-articular hyaluronan injections for the treatment of osteoarthritis: perspective for the mechanism of action. Ther Adv Musculoskelet Dis 10(2): 55-57.
• 1010 Piuzzi, N. S., et al. (2018). The Stem-Cell Market for the Treatment of Knee Osteoarthritis: A Patient Perspective. J Knee Surg 31(6): 551-556.
• 1011 Piuzzi, N. S., et al. (2018). Variability in the Preparation, Reporting, and Use of Bone Marrow Aspirate Concentrate in Musculoskeletal Disorders: A Systematic Review of the Clinical Orthopaedic Literature. J Bone Joint Surg Am 100(6): 517-525.
• 1012 Preissner, M., et al. (2018). Application of a novel in vivo imaging approach to measure pulmonary vascular responses in mice. Physiol Rep 6(19): e13875.
• 1013 Purandare, N., et al. (2018). The cellular stress proteins CHCHD10 and MNRR1 (CHCHD2): Partners in mitochondrial and nuclear function and dysfunction. J Biol Chem 293(17): 6517-6529.
• 1014 Qadan, M. A., et al. (2018). Variation in primary and culture-expanded cells derived from connective tissue progenitors in human bone marrow space, bone trabecular surface and adipose tissue. Cytotherapy 20(3): 343-360.
• 1015 Qin, J. J., et al. (2018). Caspase recruitment domain 6 protects against hepatic ischemia/reperfusion injury by suppressing ASK1. J Hepatol 69(5): 1110-1122.
• 1016 Radom-Aizik, S., et al. (2018). A Translational Model of Incomplete Catch-Up Growth: Early-Life Hypoxia and the Effect of Physical Activity. Clin Transl Sci 11(4): 412-419.
• 1017 Rand, D. M., et al. (2018). Mitonuclear epistasis, genotype-by-environment interactions, and personalized genomics of complex traits in Drosophila. IUBMB Life 70(12): 1275-1288.
• 1018 Rashid, J., et al. (2018). Fasudil and DETA NONOate, Loaded in a Peptide-Modified Liposomal Carrier, Slow PAH Progression upon Pulmonary Delivery. Mol Pharm 15(5): 1755-1765.
• 1019 Rashid, J., et al. (2018). Repurposing rosiglitazone, a PPAR-gamma agonist and oral antidiabetic, as an inhaled formulation, for the treatment of PAH. J Control Release 280: 113-123.
• 1020 Reid, E., et al. (2018). Preclinical Evaluation and Optimization of a Cell Therapy Using Human Cord Blood-Derived Endothelial Colony-Forming Cells for Ischemic Retinopathies. Stem Cells Transl Med 7(1): 59-67.
• 1021 Revhaug, C., et al. (2018). Pulmonary vascular disease is evident in gene regulation of experimental bronchopulmonary dysplasia. The Journal of Maternal-Fetal & Neonatal Medicine: 1-9
• 1022Richards, D. J. (2018). Development of Biomimetic Models of Human Cardiac Tissue. Dissertation
• 1023 Rocha, R., et al. (2018). The Adenosine A(3) Receptor Regulates Differentiation of Glioblastoma Stem-Like Cells to Endothelial Cells under Hypoxia. Int J Mol Sci 19(4).
• 1024 Ruyle, B. C., et al. (2018). Hypoxia activates a neuropeptidergic pathway from the paraventricular nucleus of the hypothalamus to the nucleus tractus solitarii. Am J Physiol Regul Integr Comp Physiol 315(6): R1167-R1182.
• 1025 Rybka, V., et al. (2018). Effects of Bcl-2/Bcl-xL Inhibitors on Pulmonary Artery Smooth Muscle Cells. Antioxidants (Basel) 7(11).
• 1026 Sagi, V., et al. (2018). Mouse Models of Pain in Sickle Cell Disease. Curr Protoc Neurosci 85(1): e54.
• 1027 Sallon, C., et al. (2018). Essential Intracrine Androgenic Action in Lung Development for Both Sexes. J Steroid Biochem Mol Biol 183: 184-191.
• 1028 Scheuer, T., et al. (2018). Neonatal Hyperoxia Perturbs Neuronal Development in the Cerebellum. Mol Neurobiol 55(5): 3901-3915.
• 1029 Serdar, M., et al. (2018). Protection of oligodendrocytes through neuronal overexpression of the small gtpase ras in hyperoxia-induced neonatal brain injury. Frontiers in neurology 9: 175
• 1030 Shafa, M., et al. (2018). Human induced pluripotent stem cell-derived lung progenitor and alveolar epithelial cells attenuate hyperoxia-induced lung injury. Cytotherapy 20(1): 108-125.
• 1031 Sharma, P., et al. (2018). Intermittent hypoxia regulates vasoactive molecules and alters insulin-signaling in vascular endothelial cells. Sci Rep 8(1): 14110.
• 1032 Sheikh, A. Q., et al. (2018). Cell Autonomous and Non-cell Autonomous Regulation of SMC Progenitors in Pulmonary Hypertension. Cell Rep 23(4): 1152-1165.
• 1033 Shigemura, M., et al. (2018). Hypercapnia increases airway smooth muscle contractility via caspase-7–mediated miR-133a–RhoA signaling. Science translational medicine 10(457)
• 1034 Shults, N. V., et al. (2018). Ligand-mediated dephosphorylation signaling for MAP kinase. Cell Signal 52: 147-154.
• 1035 Siegers, G. M., et al. (2018). Functional Plasticity of Gamma Delta T Cells and Breast Tumor Targets in Hypoxia. Front Immunol 9: 1367.
• 1036 Simmons, A. B., et al. (2018). Gene therapy knockdown of VEGFR2 in retinal endothelial cells to treat retinopathy. Angiogenesis 21(4): 751-764.
• 1037 Simmons, M. A., et al. (2018). Automatic analysis of the retinal avascular area in the rat oxygen-induced retinopathy model. Mol Vis 24: 767-777.
• 1038 Sivasubramaniyan, K., et al. (2018). Bone Marrow–Harvesting Technique Influences Functional Heterogeneity of Mesenchymal Stem/Stromal Cells and Cartilage Regeneration. The American journal of sports medicine 46(14): 3521-3531
• 1039 Snyder, B., et al. (2018). Androgens modulate chronic intermittent hypoxia effects on brain and behavior. Horm Behav 106: 62-73.
• 1040 Snyder, B., et al. (2018). Rat Strain and Housing Conditions Alter Oxidative Stress and Hormone Responses to Chronic Intermittent Hypoxia. Front Physiol 9: 1554.
• 1041 Soares, M. A., et al. (2018). Ex vivo allotransplantation engineering: Delivery of mesenchymal stem cells prolongs rejection-free allograft survival. Am J Transplant 18(7): 1657-1667.
• 1042 Sun, P., et al. (2018). Monocyte Chemoattractant Protein-Induced Protein 1 Targets Hypoxia-Inducible Factor 1alpha to Protect Against Hepatic Ischemia/Reperfusion Injury. Hepatology 68(6): 2359-2375.
• 1043 Szojka, A. R. A., et al. (2018). Hypoxia and TGF-β3 synergistically mediate inner meniscus-like matrix formation by fibrochondrocytes. Tissue Engineering(ja)
• 1044 Tamosiuniene, R., et al. (2018). Dominant Role for Regulatory T Cells in Protecting Females Against Pulmonary Hypertension. Circ Res 122(12): 1689-1702.
• 1045 Than, N. G., et al. (2018). Integrated Systems Biology Approach Identifies Novel Maternal and Placental Pathways of Preeclampsia. Front Immunol 9: 1661.
• 1046 Tripathi, A., et al. (2018). Intermittent Hypoxia and Hypercapnia, a Hallmark of Obstructive Sleep Apnea, Alters the Gut Microbiome and Metabolome. mSystems 3(3): e00020-00018.
• 1047 Tubin, S., et al. (2018). Radiation and hypoxia-induced non-targeted effects in normoxic and hypoxic conditions in human lung cancer cells. Int J Radiat Biol 94(3): 199-211.
• 1048 Vahatupa, M., et al. (2018). SWATH-MS Proteomic Analysis of Oxygen-Induced Retinopathy Reveals Novel Potential Therapeutic Targets. Invest Ophthalmol Vis Sci 59(8): 3294-3306.
• 1049 Vijayan, M., et al. (2018). Identification of novel circulatory microRNA signatures linked to patients with ischemic stroke. Hum Mol Genet 27(13): 2318-2329.
• 1050 Vozdek, R., et al. (2018). The receptor tyrosine kinase HIR-1 coordinates HIF-independent responses to hypoxia and extracellular matrix injury. Sci Signal 11(550).
• 1051 Vyas-Read, S., et al. (2018). Hyperoxia induces paracellular leak and alters claudin expression by neonatal alveolar epithelial cells. Pediatr Pulmonol 53(1): 17-27.
• 1052 Wada, Y., et al. (2018). Impact of oxygen status on 10B-BPA uptake into human glioblastoma cells, referring to significance in boron neutron capture therapy. J Radiat Res 59(2): 122-128.
• 1053 Wade, B. E., et al. (2018). Hypoxia-induced alterations in the lung ubiquitin proteasome system during pulmonary hypertension pathogenesis. Pulm Circ 8(3): 2045894018788267.
• 1054 Wallace, K., et al. (2018). Novel treatment avenues for uterine leiomyoma: a new implication for endothelin? Clin Sci (Lond) 132(20): 2261-2267.
• 1055 Wang, F., et al. (2018). Enhancing Oligodendrocyte Myelination Rescues Synaptic Loss and Improves Functional Recovery after Chronic Hypoxia. Neuron 99(4): 689-701 e685.
• 1056 Wang, F., et al. (2018). Hypoxia Enhances Differentiation of Adipose Tissue-Derived Stem Cells toward the Smooth Muscle Phenotype. Int J Mol Sci 19(2).
• 1057 Wang, F., et al. (2018). Regeneration of the oesophageal muscle layer from oesophagus acellular matrix scaffold using adipose-derived stem cells. Biochemical and biophysical research communications 503(1): 271-277
• 1058 Wang, J., et al. (2018). MicroRNA-143 modulates the expression of Natriuretic Peptide Receptor 3 in cardiac cells. Sci Rep 8(1): 7055.
• 1059 Wang, L., et al. (2018). A Core-Shell Nanoplatform for Synergistic Enhanced Sonodynamic Therapy of Hypoxic Tumor via Cascaded Strategy. Adv Healthc Mater 7(22): e1800819.
• 1060 Wang, Y., et al. (2018). Low-Frequency Intermittent Hypoxia Promotes Subcutaneous Adipogenic Differentiation. Oxid Med Cell Longev 2018: 4501757.
• 1061 Wei, Z. Z., et al. (2018). Neuroprotective and regenerative roles of intranasal Wnt-3a administration after focal ischemic stroke in mice. J Cereb Blood Flow Metab 38(3): 404-421.
• 1062 Wheatley, B. M., et al. (2018). Palovarotene inhibits connective tissue progenitor cell proliferation in a rat model of combat-related heterotopic ossification. J Orthop Res 36(4): 1135-1144.
• 1063 Willis, G. R., et al. (2018). Mesenchymal Stromal Cell Exosomes Ameliorate Experimental Bronchopulmonary Dysplasia and Restore Lung Function through Macrophage Immunomodulation. Am J Respir Crit Care Med 197(1): 104-116.
• 1064 Wilson, E. N., et al. (2018). Chronic intermittent hypoxia induces hormonal and male sexual behavioral changes: Hypoxia as an advancer of aging. Physiol Behav 189: 64-73.
• 1065 Wong, R., et al. (2018). Blockade of the swelling-induced chloride current attenuates the mouse neonatal hypoxic-ischemic brain injury in vivo. Acta Pharmacol Sin 39(5): 858-865.
• 1066 Wu, X., et al. (2018). NLRP3 in fl ammasome mediates chronic intermittent hypoxia-induced renal injury implication of the microRNA-155/FOXO3a signaling pathway. J Cell Physiol 233(12): 9404-9415.
• 1067 Xiao, C., et al. (2018). Downregulation of hypoxiainducible factor-1alpha inhibits growth, invasion, and angiogenesis of human salivary adenoid cystic carcinoma cells under hypoxia. Oncol Rep 40(3): 1675-1683.
• 1068 Xing, J., et al. (2018). Hypoxia induces senescence of bone marrow mesenchymal stem cells via altered gut microbiota. Nat Commun 9(1): 2020.
• 1069 Xu, D., et al. (2018). Rictor Deficiency Aggravates Hepatic Ischemia/Reperfusion Injury in Mice by Suppressing Autophagy and Regulating MAPK Signaling. Cell Physiol Biochem 45(6): 2199-2212.
• 1070 Xu, J., et al. (2018). Dipeptidyl peptidase IV (DPP-4) inhibition alleviates pulmonary arterial remodeling in experimental pulmonary hypertension. Lab Invest 98(10): 1333-1346.
• 1071 Yadav, V. R., et al. (2018). PLCgamma1-PKCepsilon-IP3R1 signaling plays an important role in hypoxia-induced calcium response in pulmonary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 314(5): L724-L735.
• 1072 Yang, Z., et al. (2018). Aucubin Protects against Myocardial Infarction-Induced Cardiac Remodeling via nNOS/NO-Regulated Oxidative Stress. Oxid Med Cell Longev 2018: 4327901.
• 1073 Yeligar, S. M., et al. (2018). PPARgamma Regulates Mitochondrial Structure and Function and Human Pulmonary Artery Smooth Muscle Cell Proliferation. Am J Respir Cell Mol Biol 58(5): 648-657.
• 1074 Young, S. A., et al. (2018). Mechanically resilient injectable scaffolds for intramuscular stem cell delivery and cytokine release. Biomaterials 159: 146-160.
• 1075 Yu, H., et al. (2018). 1,25(OH)2D3 attenuates pulmonary arterial hypertension via microRNA-204 mediated Tgfbr2/Smad signaling. Exp Cell Res 362(2): 311-323.
• 1076 Zaitoun, I. S., et al. (2018). Attenuation of Retinal Vascular Development in Neonatal Mice Subjected to Hypoxic-Ischemic Encephalopathy. Sci Rep 8(1): 9166.
• 1077 Zeng, F., et al. (2018). Regulating glioma stem cells by hypoxia through the Notch1 and Oct3/4 signaling pathway. Oncology letters
• 1078 Zhang, H., et al. (2018). Neurofibromin Deficiency Induces Endothelial Cell Proliferation and Retinal Neovascularization. Invest Ophthalmol Vis Sci 59(6): 2520-2528.
• 1079 Zhang, J. Y., et al. (2018). Intranasally Delivered Wnt3a Improves Functional Recovery after Traumatic Brain Injury by Modulating Autophagic, Apoptotic, and Regenerative Pathways in the Mouse Brain. J Neurotrauma 35(5): 802-813.
• 1080 Zhang, J., et al. (2018). Hypoxic culture enhances the expansion of rat bone marrow-derived mesenchymal stem cells via the regulatory pathways of cell division and apoptosis. In Vitro Cell Dev Biol Anim 54(9): 666-676.
• 1081 Zhang, J., et al. (2018). Secretory kinase Fam20C tunes endoplasmic reticulum redox state via phosphorylation of Ero1alpha. EMBO J 37(14).
• 1082 Zhang, W., et al. (2018). Hydrogen alleviates cellular senescence via regulation of ROS/p53/p21 pathway in bone marrow-derived mesenchymal stem cells in vivo. Biomed Pharmacother 106: 1126-1134.
• 1083 Zhang, Y., et al. (2018). MiR-182 alleviates the development of cyanotic congenital heart disease by suppressing HES1. Eur J Pharmacol 836: 18-24.
• 1084 Zhao, Y., et al. (2018). Changes to social feeding behaviors are not sufficient for fitness gains of the Caenorhabditis elegans N2 reference strain. eLife 7: e38675
• 1085 Zheng, X., et al. (2018). Co-immunoprecipitation Assay Using Endogenous Nuclear Proteins from Cells Cultured Under Hypoxic Conditions. JoVE (Journal of Visualized Experiments)(138): e57836
• 1086 Zhong, Y., et al. (2018). Maternal omega-3 PUFA supplementation prevents hyperoxia-induced pulmonary hypertension in the offspring. Am J Physiol Lung Cell Mol Physiol 315(1): L116-L132.
• 1087 Zhou, L., et al. (2018). Imatinib Ameliorated Retinal Neovascularization by Suppressing PDGFR-alpha and PDGFR-beta. Cell Physiol Biochem 48(1): 263-273.
• 1088 Zhu, G., et al. (2018). miR‑371b‑5p inhibits endothelial cell apoptosis in monocrotaline‑induced pulmonary arterial hypertension via PTEN/PI3K/Akt signaling pathways. Molecular medicine reports 18(6): 5489-5501.
• 1089 Zhu, M., et al. (2018). Gastrodin Protects Cardiomyocytes from Anoxia/Reoxygenation Injury by 14-3-3η. Oxidative Medicine and Cellular Longevity 2018
• 1090 Zou, Y., et al. (2018). Chronic Intermittent Hypoxia Induces the Long-Term Facilitation of Genioglossus Corticomotor Activity. Can Respir J 2018: 5941429.
• 1091Zou, Y., et al. (2018). The effect of chronic-intermittent-hypoxia on 5-HT1A receptors and GIRK-2 in dorsal raphe nucleus of rats. European Respiratory Journal 52(suppl 62): PA2540
• 1092 Zurlo, G., et al. (2018). Sirtuin 1 regulates pulmonary artery smooth muscle cell proliferation: role in pulmonary arterial hypertension. J Hypertens 36(5): 1164-1177.
• 1093 程加秋 and 张庭然 (2018). 低氧环境下中等强度运动对老年 T2DM 大鼠骨密度, 胰岛素敏感性影响研究. Chinese Journal of Osteoporosis/Zhongguo Guzhi Shusong Zazhi 24(5)
• 1094Abdul, M., et al. (2017). Exposure to 15% oxygen in vivo up‐regulates cardioprotective SUR2A without affecting ERK1/2 and AKT: a crucial role for AMPK. Journal of cellular and molecular medicine
• 1095 Adesina, S. E., et al. (2017). Hypoxia inhibits expression and function of mitochondrial thioredoxin 2 to promote pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 312(5): L599-L608.
• 1096 Akbarpour, M., et al. (2017). Altered CD8+ T-Cell Lymphocyte Function and TC1 Cell Stemness Contribute to Enhanced Malignant Tumor Properties in Murine Models of Sleep Apnea. Sleep 40(2).
• 1097 Amsellem, V., et al. (2017). Roles for the CX3CL1/CX3CR1 and CCL2/CCR2 Chemokine Systems in Hypoxic Pulmonary Hypertension. Am J Respir Cell Mol Biol 56(5): 597-608.
• 1098 An, S. M., et al. (2017). Interleukin‑6 identified as an important factor in hypoxia‑and aldehyde dehydrogenase‑based gefitinib adaptive resistance in non‑small cell lung cancer cells. Oncology letters 14(3): 3445-3454
• 1099 Asosingh, K., et al. (2017). Bone marrow transplantation prevents right ventricle disease in the caveolin-1-deficient mouse model of pulmonary hypertension. Blood Adv 1(9): 526-534.
• 1100 Barbakadze, T., et al. (2017). Subcellular Distribution of S-Nitrosylated H-Ras in Differentiated and Undifferentiated PC12 Cells during Hypoxia. Cell J 19(3): 443-451.
• 1101 Barnett, W. H., et al. (2017). Chemoreception and neuroplasticity in respiratory circuits. Exp Neurol 287(Pt 2): 153-164.
• 1102 Bavassano, C., et al. (2017). Bicistronic CACNA1A Gene Expression in Neurons Derived from Spinocerebellar Ataxia Type 6 Patient-Induced Pluripotent Stem Cells. Stem Cells Dev 26(22): 1612-1625.
• 1103 Becker, S., et al. (2017). Effect of subretinal injection on retinal structure and function in a rat oxygen-induced retinopathy model. Mol Vis 23: 832-843.
• 1104 Becker, S., et al. (2017). Protective effect of maternal uteroplacental insufficiency on oxygen-induced retinopathy in offspring: removing bias of premature birth. Sci Rep 7: 42301.
• 1105 Beharry, K. D., et al. (2017). Co-Enzyme Q10 and n-3 Polyunsaturated Fatty Acid Supplementation Reverse Intermittent Hypoxia-Induced Growth Restriction and Improved Antioxidant Profiles in Neonatal Rats. Antioxidants (Basel) 6(4).
• 1106 Betous, R., et al. (2017). Human Adipose-Derived Stem Cells Expanded Under Ambient Oxygen Concentration Accumulate Oxidative DNA Lesions and Experience Procarcinogenic DNA Replication Stress. Stem Cells Transl Med 6(1): 68-76.
• 1107 Boopathy, G. T. K., et al. (2017). Cavin-2 regulates the activity and stability of endothelial nitric-oxide synthase (eNOS) in angiogenesis. J Biol Chem 292(43): 17760-17776.
• 1108 Bordt, E. A., et al. (2017). The Putative Drp1 Inhibitor mdivi-1 Is a Reversible Mitochondrial Complex I Inhibitor that Modulates Reactive Oxygen Species. Developmental Cell 40(6): 583-594. e586.
• 1109 Boregowda, S. V., et al. (2017). IP6K1 Reduces Mesenchymal Stem/Stromal Cell Fitness and Potentiates High Fat Diet-Induced Skeletal Involution. Stem Cells 35(8): 1973-1983.
• 1110 Brodowski, L., et al. (2017). Impaired functional capacity of fetal endothelial cells in preeclampsia. PLOS ONE 12(5): e0178340.
• 1111 Burnight, E. R., et al. (2017). Using CRISPR-Cas9 to Generate Gene-Corrected Autologous iPSCs for the Treatment of Inherited Retinal Degeneration. Mol Ther 25(9): 1999-2013.
• 1112 Cabral-Miranda, F., et al. (2017). rAAV8-733-Mediated Gene Transfer of CHIP/Stub-1 Prevents Hippocampal Neuronal Death in Experimental Brain Ischemia. Mol Ther 25(2): 392-400.
• 1113 Caino, M. C., et al. (2017). Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer. J Clin Invest 127(10): 3755-3769.
• 1114 Carmona-Fontaine, C., et al. (2017). Metabolic origins of spatial organization in the tumor microenvironment. Proc Natl Acad Sci U S A 114(11): 2934-2939.
• 1115 Caroti, C. M., et al. (2017). A Novel Technique for Accelerated Culture of Murine Mesenchymal Stem Cells that Allows for Sustained Multipotency. Sci Rep 7(1): 13334.
• 1116 Chao, C. M., et al. (2017). Fgf10 deficiency is causative for lethality in a mouse model of bronchopulmonary dysplasia. The Journal of pathology 241(1): 91-103
• 1117 Chau, M., et al. (2017). Transplantation of iPS cell-derived neural progenitors overexpressing SDF-1alpha increases regeneration and functional recovery after ischemic stroke. Oncotarget 8(57): 97537-97553.
• 1118 Chen, C. C., et al. (2017). Hypoxia and hyperoxia differentially control proliferation of rat neural crest stem cells via distinct regulatory pathways of the HIF1α–CXCR4 and TP53–TPM1 proteins. Developmental Dynamics 246(3): 162-185.
• 1119 Chen, C. M., et al. (2017). Genome-Wide Analysis of DNA Methylation in Hyperoxia-Exposed Newborn Rat Lung. Lung 195(5): 661-669.
• 1120 Chen, C. M., et al. (2017). Human mesenchymal stem cells ameliorate experimental pulmonary hypertension induced by maternal inflammation and neonatal hyperoxia in rats. Oncotarget 8(47): 82366-82375.
• 1121 Chen, C. M., et al. (2017). Surfactant effects on the viability and function of human mesenchymal stem cells: in vitro and in vivo assessment. Stem Cell Res Ther 8(1): 180.
• 1122 Chen, J. Y., et al. (2017). Hypoxia-induced ADAM 17 expression is mediated by RSK1-dependent C/EBPbeta activation in human lung fibroblasts. Mol Immunol 88: 155-163.
• 1123 Chen, L., et al. (2017). Modulation of miR29a improves impaired post-ischemic angiogenesis in hyperglycemia. Exp Biol Med (Maywood) 242(14): 1432-1443.
• 1124 Chen, O., et al. (2017). High-concentration hydrogen protects mouse heart against ischemia/reperfusion injury through activation of thePI3K/Akt1 pathway. Sci Rep 7(1): 14871.
• 1125 Chen, Y. C., et al. (2017). Genome-wide gene expression array identifies novel genes related to disease severity and excessive daytime sleepiness in patients with obstructive sleep apnea. PLOS ONE 12(5): e0176575.
• 1126 Chhasatia, R., et al. (2017). Non-invasive, in vitro analysis of islet insulin production enabled by an optical porous silicon biosensor. Biosens Bioelectron 91: 515-522.
• 1127 Chirco, K. R., et al. (2017). Preparation and evaluation of human choroid extracellular matrix scaffolds for the study of cell replacement strategies. Acta Biomater 57: 293-303.
• 1128 Chirco, K. R., et al. (2017). Structural and molecular changes in the aging choroid: implications for age-related macular degeneration. Eye (Lond) 31(1): 10-25.
• 1129 Clayton, B. L., et al. (2017). The integrated stress response in hypoxia-induced diffuse white matter injury. J Neurosci.
• 1130 Coronel, M. M., et al. (2017). Mitigating hypoxic stress on pancreatic islets via in situ oxygen generating biomaterial. Biomaterials 129: 139-151.
• 1131 Cortese, R., et al. (2017). Aorta macrophage inflammatory and epigenetic changes in a murine model of obstructive sleep apnea: Potential role of CD36. Sci Rep 7: 43648.
• 1132 Cox, A. M., et al. (2017). Cumulative effects of neonatal hyperoxia on murine alveolar structure and function. Pediatr Pulmonol 52(5): 616-624.
• 1133 Darnall, R. A., et al. (2017). Early postnatal exposure to intermittent hypoxia in rodents is proinflammatory, impairs white matter integrity, and alters brain metabolism. Pediatric Research 82(1): 164-172
• 1134Davidson, C., et al. (2017). Inhibition or deletion of 11β-HSD1 does not increase angiogenesis in ischemic retinopathy. Diabetes & Metabolism
• 1135 de Toledo, S. M., et al. (2017). Genomic instability induced in distant progeny of bystander cells depends on the connexins expressed in the irradiated cells. Int J Radiat Biol 93(10): 1182-1194.
• 1136 Deliyanti, D., et al. (2017). Foxp3(+) Tregs are recruited to the retina to repair pathological angiogenesis. Nat Commun 8(1): 748.
• 1137 Dellett, M., et al. (2017). MicroRNA-containing extracellular vesicles released from endothelial colony-forming cells modulate angiogenesis during ischaemic retinopathy. J Cell Mol Med 21(12): 3405-3419.
• 1138 DeMars, K. M., et al. (2017). Spatiotemporal Changes in P-glycoprotein Levels in Brain and Peripheral Tissues Following Ischemic Stroke in Rats. J Exp Neurosci 11: 1179069517701741.
• 1139 Duscher, D., et al. (2017). Comparison of the Hydroxylase Inhibitor Dimethyloxalylglycine and the Iron Chelator Deferoxamine in Diabetic and Aged Wound Healing. Plast Reconstr Surg 139(3): 695e-706e.
• 1140 Eberly, A. R., et al. (2017). Biofilm formation by uropathogenic Escherichia coli is favored under oxygen conditions that mimic the bladder environment. International journal of molecular sciences 18(10): 2077
• 1141 Edgar, K. S., et al. (2017). BH4-Mediated Enhancement of Endothelial Nitric Oxide Synthase Activity Reduces Hyperoxia-Induced Endothelial Damage and Preserves Vascular Integrity in the Neonate. Invest Ophthalmol Vis Sci 58(1): 230-241.
• 1142 Endesfelder, S., et al. (2017). Neuroprotection by Caffeine in Hyperoxia-Induced Neonatal Brain Injury. Int J Mol Sci 18(1): 187.
• 1143 Endesfelder, S., et al. (2017). Neuroprotective effects of dexmedetomidine against hyperoxia-induced injury in the developing rat brain. PLOS ONE 12(2): e0171498.
• 1144 Engels, J., et al. (2017). Sildenafil Enhances Quantity of Immature Neurons and Promotes Functional Recovery in the Developing Ischemic Mouse Brain. Dev Neurosci 39(1-4): 287-297.
• 1145 Fang, M., et al. (2017). Hypoxia-inducible microRNA-218 inhibits trophoblast invasion by targeting LASP1: Implications for preeclampsia development. Int J Biochem Cell Biol 87: 95-103.
• 1146 Fernandez-Robredo, P., et al. (2017). Neuropilin 1 Involvement in Choroidal and Retinal Neovascularisation. PLOS ONE 12(1): e0169865.
• 1147 Forget, A., et al. (2017). IGF-2 coated porous collagen microwells for the culture of pancreatic islets. J Mater Chem B 5(2): 220-225.
• 1148 Fouda, A. Y., et al. (2017). Role of interleukin-10 in the neuroprotective effect of the Angiotensin Type 2 Receptor agonist, compound 21, after ischemia/reperfusion injury. Eur J Pharmacol 799: 128-134.
• 1149 Fu, L., et al. (2017). Tyrosine phosphorylation of Kv1. 5 is upregulated in intrauterine growth retardation rats with exaggerated pulmonary hypertension. Brazilian Journal of Medical and Biological Research 50(11)
• 1150 Fu, Z., et al. (2017). Lutein facilitates physiological revascularization in a mouse model of retinopathy of prematurity. Clin Exp Ophthalmol 45(5): 529-538.
• 1151 Galeano-Garces, C., et al. (2017). Molecular Validation of Chondrogenic Differentiation and Hypoxia Responsiveness of Platelet-Lysate Expanded Adipose Tissue-Derived Human Mesenchymal Stromal Cells. Cartilage 8(3): 283-299.
• 1152 Gao, L., et al. (2017). Circulating long noncoding RNA HOTAIR is an essential mediator of acute myocardial infarction. Cellular Physiology and Biochemistry 44(4): 1497-1508
• 1153 Garg, J., et al. (2017). Catecholamines facilitate VEGF-dependent angiogenesis via beta2-adrenoceptor-induced Epac1 and PKA activation. Oncotarget 8(27): 44732-44748.
• 1154 Gerri, C., et al. (2017). Hif-1alpha regulates macrophage-endothelial interactions during blood vessel development in zebrafish. Nat Commun 8: 15492.
• 1155 Geyer, M. C., et al. (2017). First Report of Successful Total Pancreatectomy and Islet Autotransplant in Australia. Pancreas 46(3): e18-e20.
• 1156 Gileles-Hillel, A., et al. (2017). Prolonged Exposures to Intermittent Hypoxia Promote Visceral White Adipose Tissue Inflammation in a Murine Model of Severe Sleep Apnea: Effect of Normoxic Recovery. Sleep 40(3): zsw074.
• 1157 Gong, X., et al. (2017). Effects of the Macular Carotenoid Lutein in Human Retinal Pigment Epithelial Cells. Antioxidants (Basel) 6(4): 100.
• 1158 Gopal, U. and S. V. Pizzo (2017). Cell surface GRP78 promotes tumor cell histone acetylation through metabolic reprogramming: a mechanism which modulates the Warburg effect. Oncotarget 8(64): 107947.
• 1159 Gorgens, S. W., et al. (2017). Hypoxia in Combination With Muscle Contraction Improves Insulin Action and Glucose Metabolism in Human Skeletal Muscle via the HIF-1alpha Pathway. Diabetes 66(11): 2800-2807.
• 1160 Goschl, S., et al. (2017). Comparative studies of oxaliplatin-based platinum(iv) complexes in different in vitro and in vivo tumor models. Metallomics 9(3): 309-322.
• 1161 Gozal, D., et al. (2017). Temporal trajectories of novel object recognition performance in mice exposed to intermittent hypoxia. Eur Respir J 50(6).
• 1162 Gozal, E., et al. (2017). PKA activity exacerbates hypoxia-induced ROS formation and hypoxic injury in PC-12 cells. Toxicol Lett 279: 107-114.
• 1163 Green, D. E., et al. (2017). Peroxisome proliferator-activated receptor-γ enhances human pulmonary artery smooth muscle cell apoptosis through microRNA-21 and programmed cell death 4. American Journal of Physiology-Lung Cellular and Molecular Physiology 313(2): L371-L383
• 1164 Grzegorzewska, A. P., et al. (2017). Dimethyl Fumarate ameliorates pulmonary arterial hypertension and lung fibrosis by targeting multiple pathways. Sci Rep 7: 41605.
• 1165 Guo, J., et al. (2017). PRAS40 Connects Microenvironmental Stress Signaling to Exosome-Mediated Secretion. Mol Cell Biol 37(19).
• 1166 Guo, S., et al. (2017). Involvement of Ca 2+-activated K+ channel 3.1 in hypoxia-induced pulmonary arterial hypertension and therapeutic effects of TRAM-34 in rats. Bioscience Reports: BSR20170763
• 1167 Gupta, N., et al. (2017). Cocktail of superoxide dismutase and fasudil encapsulated in targeted liposomes slows PAH progression at a reduced dosing frequency. Molecular pharmaceutics 14(3): 830-841
• 1168 Gutsaeva, D. R., et al. (2017). STAT3-mediated activation of miR-21 is involved in down-regulation of TIMP3 and neovascularization in the ischemic retina. Oncotarget 8(61): 103568-103580.
• 1169 Gwoździńska, P., et al. (2017). Hypercapnia Impairs ENaC Cell Surface Stability by Promoting Phosphorylation, Polyubiquitination and Endocytosis of β-ENaC in a Human Alveolar Epithelial Cell Line. Frontiers in Immunology 8
• 1170 Ha, W. H., et al. (2017). Recombinant human bone morphogenic protein-2 Induces the Differentiation and Mineralization of Osteoblastic Cells Under Hypoxic Conditions via Activation of Protein Kinase D and p38 Mitogen-Activated Protein Kinase Signaling Pathways. Tissue Eng Regen Med 14(4): 433-441.
• 1171 Heywood, H. K. and D. A. Lee (2017). Bioenergetic reprogramming of articular chondrocytes by exposure to exogenous and endogenous reactive oxygen species and its role in the anabolic response to low oxygen. J Tissue Eng Regen Med 11(8): 2286-2294.
• 1172 Hirahara, S., et al. (2017). Suppression of Retinal Neovascularization by Anti-CCR3 Treatment in an Oxygen-Induced Retinopathy Model in Mice. Ophthalmic Res 58(1): 56-66.
• 1173 Holmes-Walker, D. J., et al. (2017). Islet Transplantation Provides Superior Glycemic Control With Less Hypoglycemia Compared With Continuous Subcutaneous Insulin Infusion or Multiple Daily Insulin Injections. Transplantation 101(6): 1268-1275.
• 1174 Huang, H. L., et al. (2017). Role of integrin-linked kinase in regulating the protein stability of the MUC1-C oncoprotein in pancreatic cancer cells. Oncogenesis 6(7): e359.
• 1175 Huang, S., et al. (2017). GSK-3beta inhibitor TDZD-8 reduces neonatal hypoxic-ischemic brain injury in mice. CNS Neurosci Ther 23(5): 405-415.
• 1176 Huang, S., et al. (2017). Transient receptor potential melastatin 2 channels (TRPM2) mediate neonatal hypoxic-ischemic brain injury in mice. Exp Neurol 296: 32-40.
• 1177 Huang, X., et al. (2017). Genome editing abrogates angiogenesis in vivo. Nat Commun 8(1): 112.
• 1178 Hufgard, J. R., et al. (2017). Phosphodiesterase-1b (Pde1b) knockout mice are resistant to forced swim and tail suspension induced immobility and show upregulation of Pde10a. Psychopharmacology (Berl) 234(12): 1803-1813.
• 1179 Huizenga, M. N., et al. (2017). Anticonvulsant effect of cannabinoid receptor agonists in models of seizures in developing rats. Epilepsia 58(9): 1593-1602.
• 1180 Huuskonen, M. T., et al. (2017). The copper bis (thiosemicarbazone) complex Cu II (atsm) is protective against cerebral ischemia through modulation of the inflammatory milieu. Neurotherapeutics 14(2): 519-532
• 1181 Ianniciello, A., et al. (2017). Chronic myeloid leukemia progenitor cells require autophagy when leaving hypoxia-induced quiescence. Oncotarget 8(57): 96984
• 1182 Ibrahim, Y. F., et al. (2017). Docetaxel Reverses Pulmonary Vascular Remodeling by Decreasing Autophagy and Resolves Right Ventricular Fibrosis. J Pharmacol Exp Ther 363(1): 20-34.
• 1183 Ito, M., et al. (2017). Genetic ablation of Bach1 gene enhances recovery from hyperoxic lung injury in newborn mice via transient upregulation of inflammatory genes. Pediatr Res 81(6): 926-931.
• 1184 Jamali, N., et al. (2017). Vitamin D receptor expression is essential during retinal vascular development and attenuation of neovascularization by 1, 25 (OH) 2D3. PLOS ONE 12(12)
• 1185 Jin, M., et al. (2017). Glycolytic Enzymes Coalesce in G Bodies under Hypoxic Stress. Cell Rep 20(4): 895-908.
• 1186 Kang, H. H., et al. (2017). Chronic intermittent hypoxia induces liver fibrosis in mice with diet-induced obesity via TLR4/MyD88/MAPK/NF-kB signaling pathways. Biochem Biophys Res Commun 490(2): 349-355.
• 1187 Kathiriya, J. J., et al. (2017). Galectin-1 inhibition attenuates profibrotic signaling in hypoxia-induced pulmonary fibrosis. Cell Death Discov 3(1): 17010.
• 1188 Kawaguchi, T., et al. (2017). Probucol attenuates hyperoxia-induced lung injury in mice. PLOS ONE 12(4): e0175129.
• 1189 Kerr, F., et al. (2017). Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease. PLOS Genetics 13(3)
• 1190 Khalyfa, A., et al. (2017). Late gestational intermittent hypoxia induces metabolic and epigenetic changes in male adult offspring mice. J Physiol 595(8): 2551-2568.
• 1191 Kim, H., et al. (2017). Histological and functional assessment of the efficacy of constraint-induced movement therapy in rats following neonatal hypoxic-ischemic brain injury. Exp Ther Med 13(6): 2775-2782.
• 1192 Kim, K. L. and W. Suh (2017). Apatinib, an Inhibitor of Vascular Endothelial Growth Factor Receptor 2, Suppresses Pathologic Ocular Neovascularization in Mice. Invest Ophthalmol Vis Sci 58(9): 3592-3599.
• 1193 Kitagawa, M. G., et al. (2017). hemodynamic and Pathologic characterization of the TasK-1−/− Mouse Does not Demonstrate Pulmonary hypertension. Frontiers in medicine 4: 177
• 1194 Klein, C., et al. (2017). Overcoming hypoxia-induced tumor radioresistance in non-small cell lung cancer by targeting DNA-dependent protein kinase in combination with carbon ion irradiation. Radiat Oncol 12(1): 208.
• 1195 Klimkiewicz, K., et al. (2017). A 3D model of tumour angiogenic microenvironment to monitor hypoxia effects on cell interactions and cancer stem cell selection. Cancer Lett 396: 10-20.
• 1196 Klofers, M., et al. (2017). Effects of Poly(ADP-Ribose) Polymerase-1 Inhibition in a Neonatal Rodent Model of Hypoxic-Ischemic Injury. Biomed Res Int 2017: 2924848.
• 1197 Kobayashi, K., et al. (2017). Dynamics of angiogenesis in ischemic areas of the infarcted heart. Sci Rep 7(1): 7156.
• 1198 Korayem, A. H., et al. (2017). Endothelial cAMP deactivates ischemia/reperfusion-induced microvascular hyperpermeability via Rap1-mediated mechanisms. American Journal of Physiology-Heart and Circulatory Physiology: ajpheart. 00002.02017
• 1199 Kumar, R., et al. (2017). TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma-and hypoxia-induced pulmonary hypertension. Nature communications 8(1): 1-13
• 1200 Kuo, C.-W., et al. (2017). mtDNA as a Mediator for Expression of Hypoxia-Inducible Factor 1α and ROS in Hypoxic Neuroblastoma Cells. International journal of molecular sciences 18(6): 1220.
• 1201 Kusuma, G. D., et al. (2017). Effect of the Microenvironment on Mesenchymal Stem Cell Paracrine Signaling: Opportunities to Engineer the Therapeutic Effect. Stem Cells Dev 26(9): 617-631.
• 1202 Labuz, J. M., et al. (2017). Building an experimental model of the human body with non-physiological parameters. Technology (Singap World Sci) 5(1): 42-59.
• 1203 Lajko, M., et al. (2017). Photoreceptor oxidative stress in hyperoxia-induced proliferative retinopathy accelerates rd8 degeneration. PLOS ONE 12(7): e0180384.
• 1204 Lamothe, S. M., et al. (2017). Hypoxia reduces mature hERG channels through calpain up-regulation. The FASEB Journal 31(11): 5068-5077
• 1205 Laouafa, S., et al. (2017). Estradiol Protects Against Cardiorespiratory Dysfunctions and Oxidative Stress in Intermittent Hypoxia. Sleep 40(8).
• 1206 Lee, J., et al. (2017). Plastic roles of pericytes in the blood–retinal barrier. Nature communications 8(1): 1-16
• 1207 Lee, S., et al. (2017). Analysis of CCN Protein Expression and Activities in Vasoproliferative Retinopathies. Methods Mol Biol 1489: 543-556.
• 1208 Lee, S., et al. (2017). Interplay between CCN1 and Wnt5a in endothelial cells and pericytes determines the angiogenic outcome in a model of ischemic retinopathy. Scientific Reports 7
• 1209 Li, C., et al. (2017). Protective effect of cyanidin-3-O-glucoside on neonatal porcine islets. J Endocrinol 235(3): 237-249.
• 1210 Li, C., et al. (2017). Rapamycin Promotes the Survival and Adipogenesis of Ischemia-Challenged Adipose Derived Stem Cells by Improving Autophagy. Cell Physiol Biochem 44(5): 1762-1774.
• 1211 Li, F., et al. (2017). Orientin reduces myocardial infarction size via eNOS/NO signaling and thus mitigates adverse cardiac remodeling. Frontiers in pharmacology 8: 926
• 1212 Li, G., et al. (2017). Fork Head Box Class O1 (FOXO1) Activates Bim Expression to Mediate Cardiac Apoptosis in Chronic Intermittent Hypoxia-Induced Cardiac Hypertrophy. Med Sci Monit 23: 3603-3616.
• 1213 Li, H., et al. (2017). Loss of CD73-mediated extracellular adenosine production exacerbates inflammation and abnormal alveolar development in newborn mice exposed to prolonged hyperoxia. Pediatr Res 82(6): 1039-1047.
• 1214 Li, L., et al. (2017). Forkhead box O3 (FoxO3) regulates kidney tubular autophagy following urinary tract obstruction. J Biol Chem 292(33): 13774-13783.
• 1215 Liao, P. L., et al. (2017). Anti-inflammatory properties of shikonin contribute to improved early-stage diabetic retinopathy. Sci Rep 7: 44985.
• 1216 Lim, R., et al. (2017). A Pilot Study Evaluating the Safety of Intravenously Administered Human Amnion Epithelial Cells for the Treatment of Hepatic Fibrosis. Front Pharmacol 8: 549.
• 1217 Lin, Y. J., et al. (2017). Tumor Hypoxia Regulates Forkhead Box C1 to Promote Lung Cancer Progression. Theranostics 7(5): 1177-1191.
• 1218 Liu, K. X., et al. (2017). Inhibition of microRNA-218 reduces HIF-1alpha by targeting on Robo1 in mice aortic endothelial cells under intermittent hypoxia. Oncotarget 8(61): 104359-104366.
• 1219 Liu, Y., et al. (2017). Gremlin promotes retinal pigmentation epithelial (RPE) cell proliferation, migration and VEGF production via activating VEGFR2-Akt-mTORC2 signaling. Oncotarget 8(1): 979-987.
• 1220 Loncaric, D., et al. (2017). To harness stem cells by manipulation of energetic metabolism. Transfus Clin Biol 24(4): 468-471.
• 1221 Looney, A. P., et al. (2017). Synergistic Role of Endothelial ERG and FLI1 in Mediating Pulmonary Vascular Homeostasis. Am J Respir Cell Mol Biol 57(1): 121-131.
• 1222 Lu, L., et al. (2017). Placental Stem Villus Arterial Remodeling Associated with Reduced Hydrogen Sulfide Synthesis Contributes to Human Fetal Growth Restriction. Am J Pathol 187(4): 908-920.
• 1223 Lu, Y., et al. (2017). Glucose-6-Phosphate Isomerase (G6PI) Mediates Hypoxia-Induced Angiogenesis in Rheumatoid Arthritis. Sci Rep 7: 40274.
• 1224 Luo, M., et al. (2017). Annexin A2 supports pulmonary microvascular integrity by linking vascular endothelial cadherin and protein tyrosine phosphatases. J Exp Med 214(9): 2535-2545.
• 1225 Lynch, B., et al. (2017). The effect of hypoxia on thermosensitive poly(N-vinylcaprolactam) hydrogels with tunable mechanical integrity for cartilage tissue engineering. J Biomed Mater Res B Appl Biomater 105(7): 1863-1873.
• 1226 Mankouski, A., et al. (2017). Intermittent hypoxia during recovery from neonatal hyperoxic lung injury causes long-term impairment of alveolar development: A new rat model of BPD. Am J Physiol Lung Cell Mol Physiol 312(2): L208-L216.
• 1227 Mantripragada, V. P., et al. (2017). Histopathological assessment of primary osteoarthritic knees in large patient cohort reveal the possibility of several potential patterns of osteoarthritis initiation. Curr Res Transl Med 65(4): 133-139.
• 1228 Massa, A., et al. (2017). The effect of extracellular acidosis on the behaviour of mesenchymal stem cells in vitro. Eur Cell Mater 33: 252-267.
• 1229 Masuda, T., et al. (2017). Apolipoprotein E2 and E3, but Not E4, Promote Retinal Pathologic NeovascularizationApoE2 and ApoE3 Promote Retinal Angiogenesis. Investigative Ophthalmology & Visual Science 58(2): 1208-1217
• 1230 Mata-Greenwood, E., et al. (2017). Comparative and Experimental Studies on the Genes Altered by Chronic Hypoxia in Human Brain Microendothelial Cells. Front Physiol 8: 365.
• 1231 Mathieu, R., et al. (2017). Neonatal exposure to high oxygen levels leads to impaired ischemia-induced neovascularization in adulthood. Sci Rep 7(1): 14143.
• 1232 Matsumoto, T., et al. (2017). Retinal VEGF levels correlate with ocular circulation measured by a laser speckle-micro system in an oxygen-induced retinopathy rat model. Graefes Arch Clin Exp Ophthalmol 255(10): 1981-1990.
• 1233McIntyre, L., et al. (2017). Cellular immunotherapy for septic shock (CISS): a phase I trial. Cytotherapy 19(5): e3-e4
• 1234 Meinert, C., et al. (2017). A novel bioreactor system for biaxial mechanical loading enhances the properties of tissue-engineered human cartilage. Sci Rep 7(1): 16997.
• 1235 Mendez-Sanchez, J. F. and W. W. Burggren (2017). Cardiorespiratory physiological phenotypic plasticity in developing air-breathing anabantid fishes (Betta splendens and Trichopodus trichopterus). Physiol Rep 5(15).
• 1236 Mills, D. R., et al. (2017). Effects of human umbilical cord blood mononuclear cells on respiratory system mechanics in a murine model of neonatal lung injury. Exp Lung Res 43(2): 66-81.
• 1237 Mossman, J. A., et al. (2017). Mitonuclear Interactions Mediate Transcriptional Responses to Hypoxia in Drosophila. Mol Biol Evol 34(2): 447-466.
• 1238 Moya, A., et al. (2017). Quiescence Preconditioned Human Multipotent Stromal Cells Adopt a Metabolic Profile Favorable for Enhanced Survival under Ischemia. Stem Cells 35(1): 181-196.
• 1239 Murata, K., et al. (2017). Hypoxia-Sensitive COMMD1 Integrates Signaling and Cellular Metabolism in Human Macrophages and Suppresses Osteoclastogenesis. Immunity 47(1): 66-79 e65.
• 1240 Muthyala, S., et al. (2017). The effect of hypoxia on free and encapsulated adult porcine islets-an in vitro study. Xenotransplantation 24(1).
• 1241 Nagaraj, C., et al. (2017). Hypoxic vascular response and ventilation/perfusion matching in end-stage COPD may depend on p22phox. Eur Respir J 50(1).
• 1242 Nagy, B. M., et al. (2017). Importance of kynurenine in pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 313(5): L741-L751.
• 1243 Nagy, B. M., et al. (2017). Lack of ABCG2 Leads to Biventricular Dysfunction and Remodeling in Response to Hypoxia. Front Physiol 8: 98.
• 1244 Nakagawa, M., et al. (2017). Impaired nephrogenesis in neonatal rats with oxygen-induced retinopathy. Pediatr Int 59(6): 704-710.
• 1245 Ng, M., et al. (2017). Stem cell industry update: 2012 to 2016 reveals accelerated investment, but market capitalization and earnings lag. Cytotherapy 19(10): 1131-1139.
• 1246 Nie, X., et al. (2017). Noradrenergic Activation of Hypoglossal Nucleus Modulates the Central Regulation of Genioglossus in Chronic Intermittent Hypoxic Rats. Front Neurol 8(171): 171.
• 1247 Nowak, G., et al. (2017). Deletion of protein kinase C-epsilon attenuates mitochondrial dysfunction and ameliorates ischemic renal injury. Am J Physiol Renal Physiol 312(1): F109-F120.
• 1248 Ortega, J. A., et al. (2017). Oxygen Levels Regulate the Development of Human Cortical Radial Glia Cells. Cereb Cortex 27(7): 3736-3751.
• 1249 Ortega, O., et al. (2017). [STAT3 activation by hypoxia in in vitro models of cervix cancer and endothelial cells]. Biomédica 37(1): 119-130.
• 1250 O’Shea, K. M., et al. (2017). The Formin, DIAPH1, is a Key Modulator of Myocardial Ischemia/Reperfusion Injury. EBioMedicine 26(Supplement C): 165-174.
• 1251 Oshikawa, M., et al. (2017). Affinity-Immobilization of VEGF on Laminin Porous Sponge Enhances Angiogenesis in the Ischemic Brain. Adv Healthc Mater 6(11): 1700183-n/a.
• 1252 Oshikawa, M., et al. (2017). Dnmt1-dependent Chk1 pathway suppression is protective against neuron division. Development 144(18): 3303-3314
• 1253 Patel, H., et al. (2017). Hypoxia-induced activation of specific members of the NF-kB family and its relevance to pulmonary vascular remodeling. Int J Biochem Cell Biol 92(Supplement C): 141-147.
• 1254 Patterson, T. E., et al. (2017). The Efficiency of Bone Marrow Aspiration for the Harvest of Connective Tissue Progenitors from the Human Iliac Crest. J Bone Joint Surg Am 99(19): 1673-1682.
• 1255 Pedersen, A. K., et al. (2017). Tumor microenvironment conditions alter Akt and Na(+)/H(+) exchanger NHE1 expression in endothelial cells more than hypoxia alone: implications for endothelial cell function in cancer. BMC cancer 17(1): 542.
• 1256 Penumatsa, K. C., et al. (2017). Transglutaminase 2 in pulmonary and cardiac tissue remodeling in experimental pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 313(5): L752-L762.
• 1257 Perez, M., et al. (2017). Aberrant cGMP signaling persists during recovery in mice with oxygen-induced pulmonary hypertension. PLOS ONE 12(8): e0180957.
• 1258 Phillips, T. J., et al. (2017). Treating the placenta to prevent adverse effects of gestational hypoxia on fetal brain development. Sci Rep 7(1): 9079.
• 1259 Phinney, D. G. and M. F. Pittenger (2017). Concise Review: MSC-Derived Exosomes for Cell-Free Therapy. Stem Cells 35(4): 851-858.
• 1260 Piuzzi, N. S. and G. F. Muschler (2017). CORR Insights((R)): Which Clinical and Patient Factors Influence the National Economic Burden of Hospital Readmissions After Total Joint Arthroplasty. Clin Orthop Relat Res 475(12): 2938-2940.
• 1261 Piuzzi, N. S., et al. (2017). Analysis of Cell Therapies Used in Clinical Trials for the Treatment of Osteonecrosis of the Femoral Head: A Systematic Review of the Literature. J Arthroplasty 32(8): 2612-2618.
• 1262 Piuzzi, N. S., et al. (2017). Cellular Therapies in Orthopedics: Where Are We? Surg Technol Int 31: 359-364.
• 1263 Piuzzi, N. S., et al. (2017). Evidence for the Use of Cell-Based Therapy for the Treatment of Osteonecrosis of the Femoral Head: A Systematic Review of the Literature. J Arthroplasty 32(5): 1698-1708.
• 1264 Piuzzi, N. S., et al. (2017). Platelet-Rich Plasma for the Treatment of Knee Osteoarthritis: A Review. J Knee Surg 30(7): 627-633.
• 1265 Polke, M., et al. (2017). Hypoxia and the hypoxia-regulated transcription factor HIF-1alpha suppress the host defence of airway epithelial cells. Innate Immun 23(4): 373-380.
• 1266 Polsek, D., et al. (2017). A novel adjustable automated system for inducing chronic intermittent hypoxia in mice. PLOS ONE 12(3): e0174896.
• 1267 Prokesch, A., et al. (2017). Placental DAPK1 and autophagy marker LC3B-II are dysregulated by TNF-alpha in a gestational age-dependent manner. Histochem Cell Biol 147(6): 695-705.
• 1268Qian, Z., et al. (2017). Effects of Short Term Hypoxia-Preconditioning on Glial Phenotype Induction of Human Mesenchymal Stem Cells. AIMS Cell and Tissue Engineering 1(1): 47
• 1269 Qin, J., et al. (2017). Hypoxia-inducible factor 1 alpha promotes cancer stem cells-like properties in human ovarian cancer cells by upregulating SIRT1 expression. Sci Rep 7(1): 10592.
• 1270 Quan, M., et al. (2017). MnTBAP or catalase is more protective against oxidative stress in human retinal endothelial cells exposed to intermittent hypoxia than their co-administration (EUK-134). Reactive Oxygen Species 3(7)
• 1271Rakocinski, C. F. and K. B. Gillam (2017). Temperature-modulated expression of allometric respiration strategies supports a metabolic scaling rule. Frontiers in Marine Science 4: 261
• 1272 Ramachandran, S., et al. (2017). Plasma microvesicle analysis identifies microRNA 129-5p as a biomarker of heart failure in univentricular heart disease. PLOS ONE 12(8): e0183624.
• 1273 Ramkumar, P. N., et al. (2017). Cellular therapy injections in today’s orthopedic market: A social media analysis. Cytotherapy 19(12): 1392-1399.
• 1274 Rashid, J., et al. (2017). Inhaled sildenafil as an alternative to oral sildenafil in the treatment of pulmonary arterial hypertension (PAH). Journal of Controlled Release 250: 96-106
• 1275 Raudenska, M., et al. (2017). VPA does not enhance platinum binding to DNA in cisplatin-resistant neuroblastoma cancer cells. Tumour Biol 39(9): 1010428317711656.
• 1276 Ren, H. and K. Hu (2017). Inflammatory and oxidative stress‑associated factors in chronic intermittent hypoxia in Chinese patients, rats, lymphocytes and endotheliocytes. Molecular medicine reports 16(6): 8092-8102
• 1277 Ren, H., et al. (2017). Stem Cell Factor/Kit Signal Insufficiency Contributes to Hypoxia-Induced Intestinal Motility Dysfunctions in Neonatal Mice. Dig Dis Sci 62(5): 1193-1203.
• 1278 Ren, J., et al. (2017). Losartan attenuates aortic endothelial apoptosis induced by chronic intermittent hypoxia partly via the phospholipase C pathway. Sleep Breath 21(3): 679-689.
• 1279 Richards, D. J., et al. (2017). Inspiration from heart development: Biomimetic development of functional human cardiac organoids. Biomaterials 142: 112-123.
• 1280 Riffle, S., et al. (2017). Linking hypoxia, DNA damage and proliferation in multicellular tumor spheroids. BMC cancer 17(1): 338.
• 1281 Riis, S., et al. (2017). Hypoxia enhances the wound-healing potential of adipose-derived stem cells in a novel human primary keratinocyte-based scratch assay. Int J Mol Med 39(3): 587-594.
• 1282 Rivera, J. C., et al. (2017). Tetrahydrobiopterin (BH4) deficiency is associated with augmented inflammation and microvascular degeneration in the retina. J Neuroinflammation 14(1): 181.
• 1283 Roeper, M., et al. (2017). Semiautomatic High-Content Analysis of Complex Images from Cocultures of Vascular Smooth Muscle Cells and Macrophages: A CellProfiler Showcase. SLAS Discov 22(7): 837-847.
• 1284 Roy, S., et al. (2017). Autophagy-Dependent Shuttling of TBC1D5 Controls Plasma Membrane Translocation of GLUT1 and Glucose Uptake. Mol Cell 67(1): 84-95 e85.
• 1285 Rumsey, W. L., et al. (2017). Effects of airborne toxicants on pulmonary function and mitochondrial DNA damage in rodent lungs. Mutagenesis 32(3): 343-353.
• 1286 Ryu, H. W., et al. (2017). HDAC6 regulates sensitivity to cell death in response to stress and post-stress recovery. Cell Stress Chaperones 22(2): 253-261.
• 1287 Sacchetti, B., et al. (2017). Effect of miR-204&211 and RUNX2 control on the fate of human mesenchymal stromal cells. Regen Med Res 5: 2.
• 1288 Sandvig, I., et al. (2017). Strategies to Enhance Implantation and Survival of Stem Cells After Their Injection in Ischemic Neural Tissue. Stem Cells Dev 26(8): 554-565.
• 1289 Sandvoß, M., et al. (2017). HELLP Syndrome: Altered Hypoxic Response of the Fatty Acid Oxidation Regulator SIRT 4. Reproductive Sciences 24(4): 568-574.
• 1290 Scharping, N. E., et al. (2017). Efficacy of PD-1 Blockade Is Potentiated by Metformin-Induced Reduction of Tumor Hypoxia. Cancer Immunol Res 5(1): 9-16.
• 1291 Schlosser, K., et al. (2017). Lack of elevation in plasma levels of pro-inflammatory cytokines in common rodent models of pulmonary arterial hypertension: questions of construct validity for human patients. Pulm Circ 7(2): 476-485.
• 1292 Schwingshackl, A., et al. (2017). Hyperoxia treatment of TREK-1/TREK-2/TRAAK-deficient mice is associated with a reduction in surfactant proteins. Am J Physiol Lung Cell Mol Physiol 313(6): L1030-L1046.
• 1293Schwingshackl, A., et al. (2017). Translational Research in Acute Lung Injury and Pulmonary Fibrosis: Hyperoxia treatment of TREK-1/TREK-2/TRAAK-deficient mice is associated with a reduction in surfactant proteins. American Journal of Physiology-Lung Cellular and Molecular Physiology 313(6): L1030
• 1294 Sethumadhavan, S., et al. (2017). Hypoxia and hypoxia-inducible factor (HIF) downregulate antigen-presenting MHC class I molecules limiting tumor cell recognition by T cells. PLOS ONE 12(11): e0187314.
• 1295 Shan, L. N., et al. (2017). The significant effect of chronic intermittent hypoxia on prostaglandin D2 biosynthesis in rat brain. Biochem Biophys Res Commun 483(1): 283-287.
• 1296 Sharma, S., et al. (2017). Mitochondrial complex II regulates a distinct oxygen sensing mechanism in monocytes. Hum Mol Genet 26(7): 1328-1339.
• 1297 Sharma, S., et al. (2017). Transient overexpression of exogenous APOBEC3A causes C-to-U RNA editing of thousands of genes. RNA Biol 14(5): 603-610.
• 1298 Sharma, T. P., et al. (2017). Patient-specific induced pluripotent stem cells to evaluate the pathophysiology of TRNT1-associated Retinitis pigmentosa. Stem Cell Res 21: 58-70.
• 1299 Shi, Y. J., et al. (2017). The integration of multiple signaling pathways provides for bidirectional control of CRHR1 gene transcription in rat pituitary cell during hypoxia. Mol Cell Endocrinol 454: 12-22.
• 1300 Shi, Y., et al. (2017). Monitoring and Targeting Anti-VEGF Induced Hypoxia within the Viable Tumor by (19)F-MRI and Multispectral Analysis. Neoplasia 19(11): 950-959.
• 1301 Singh, J. N., et al. (2017). Quantifying three-dimensional rodent retina vascular development using optical tissue clearing and light-sheet microscopy. J Biomed Opt 22(7): 76011.
• 1302 Sniegon, I., et al. (2017). Endothelial mesenchymal transition in hypoxic microvascular endothelial cells and paracrine induction of cardiomyocyte apoptosis are mediated via TGFβ1/SMAD signaling. International journal of molecular sciences 18(11): 2290
• 1303 Son, J. H., et al. (2017). A novel combination treatment to stimulate bone healing and regeneration under hypoxic conditions: photobiomodulation and melatonin. Lasers Med Sci 32(3): 533-541.
• 1304 Song, A., et al. (2017). Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent. Nature communications 8: 14108
• 1305 Songstad, A. E., et al. (2017). Connective Tissue Growth Factor Promotes Efficient Generation of Human Induced Pluripotent Stem Cell-Derived Choroidal Endothelium. Stem Cells Transl Med 6(6): 1533-1546.
• 1306 Stokes, R. A., et al. (2017). Transplantation sites for human and murine islets. Diabetologia 60(10): 1961-1971.
• 1307 Suh, J. H., et al. (2017). Steroid receptor coactivator-2 (SRC-2) coordinates cardiomyocyte paracrine signaling to promote pressure overload–induced angiogenesis. Journal of Biological Chemistry 292(52): 21643-21652
• 1308 Tang, M., et al. (2017). Discordant mRNA and protein expression of CXCR4 under in vitro CoCl 2-induced hypoxic conditions. Biochemical and biophysical research communications 484(2): 285-291
• 1309 Tang, X., et al. (2017). hCLOCK induction by hypoxia promotes inflammatory responses by activating the NF‑κB pathway. Molecular medicine reports 15(3): 1401-1406.
• 1310 Tatin, F., et al. (2017). Apelin modulates pathological remodeling of lymphatic endothelium after myocardial infarction. JCI Insight 2(12).
• 1311 Tejchman, A., et al. (2017). Tumor hypoxia modulates podoplanin/CCL21 interactions in CCR7+ NK cell recruitment and CCR7+ tumor cell mobilization. Oncotarget 8(19): 31876-31887.
• 1312 Teo, J. D., et al. (2017). Hypoxic postconditioning improves behavioural deficits at 6 weeks following hypoxic-ischemic brain injury in neonatal rats. Behavioural brain research 333: 27-34
• 1313 Teo, J. D., et al. (2017). Maternal obesity increases inflammation and exacerbates damage following neonatal hypoxic-ischaemic brain injury in rats. Brain Behav Immun 63: 186-196.
• 1314 Thiagarajan, D., et al. (2017). Aldose reductase modulates acute activation of mesenchymal markers via the beta-catenin pathway during cardiac ischemia-reperfusion. PLOS ONE 12(11): e0188981.
• 1315 Tilwani, R. K., et al. (2017). Oxygen tension modulates the effects of TNFalpha in compressed chondrocytes. Inflamm Res 66(1): 49-58.
• 1316 Touma, M., et al. (2017). Wnt11 regulates cardiac chamber development and disease during perinatal maturation. JCI Insight 2(17).
• 1317 Truong, G., et al. (2017). Oxygen tension regulates the miRNA profile and bioactivity of exosomes released from extravillous trophoblast cells–liquid biopsies for monitoring complications of pregnancy. PLOS ONE 12(3)
• 1318 Tsang, K. M., et al. (2017). Embryonic Stem Cell Differentiation to Functional Arterial Endothelial Cells through Sequential Activation of ETV2 and NOTCH1 Signaling by HIF1α. Stem Cell Reports
• 1319 Turan, S., et al. (2017). Chronic hypoxia alters maternal uterine and fetal hemodynamics in the full-term pregnant guinea pig. Am J Physiol Regul Integr Comp Physiol 313(4): R330-R339.
• 1320van Dijk, I., et al. (2017). COMBINED IMPACTS OF OCEAN ACIDIFICATION AND DYSOXIA ON SURVIVAL AND GROWTH OF FOUR AGGLUTINATING FORAMINIFERA. Journal of Foraminiferal Research 47(3): 294-303
• 1321 Vang, A., et al. (2017). Effect of α7 nicotinic acetylcholine receptor activation on cardiac fibroblasts: a mechanism underlying RV fibrosis associated with cigarette smoke exposure. American Journal of Physiology-Lung Cellular and Molecular Physiology 312(5): L748-L759.
• 1322 Vargas, V. E., et al. (2017). Gestational hypoxia disrupts the neonatal leptin surge and programs hyperphagia and obesity in male offspring in the Sprague-Dawley rat. PLOS ONE 12(9): e0185272.
• 1323 Villacampa, P., et al. (2017). Accelerated oxygen-induced retinopathy is a reliable model of ischemia-induced retinal neovascularization. PLOS ONE 12(6): e0179759.
• 1324 Vuletic, I., et al. (2017). Validation of Bevacizumab Therapy Effect on Colon Cancer Subtypes by Using Whole Body Imaging in Mice. Mol Imaging Biol 19(6): 847-856.
• 1325 Wakeland, A. K., et al. (2017). Hypoxia Directs Human Extravillous Trophoblast Differentiation in a Hypoxia-Inducible Factor-Dependent Manner. Am J Pathol 187(4): 767-780.
• 1326 Wang, D., et al. (2017). BIRC3 is a biomarker of mesenchymal habitat of glioblastoma, and a mediator of survival adaptation in hypoxia-driven glioblastoma habitats. Sci Rep 7(1): 9350.
• 1327 Wang, H., et al. (2017). Mesenchymal stem cells microvesicles stabilize endothelial barrier function partly mediated by hepatocyte growth factor (HGF). Stem Cell Res Ther 8(1): 211.
• 1328 Wang, S., et al. (2017). Bim expression in endothelial cells and pericytes is essential for regression of the fetal ocular vasculature. PLOS ONE 12(5): e0178198.
• 1329 Wang, Z. H., et al. (2017). Inhibition of Rho-kinase Attenuates Left Ventricular Remodeling Caused by Chronic Intermittent Hypoxia in Rats via Suppressing Myocardial Inflammation and Apoptosis. J Cardiovasc Pharmacol 70(2): 102-109.
• 1330 Wani, A., et al. (2017). Surface PEGylation of Mesoporous Silica Nanorods (MSNR): Effect on loading, release, and delivery of mitoxantrone in hypoxic cancer cells. Sci Rep 7(1): 2274.
• 1331 Wiley, L. A., et al. (2017). Generation of Xeno-Free, cGMP-Compliant Patient-Specific iPSCs from Skin Biopsy. Curr Protoc Stem Cell Biol 42: 4A 12 11-14A 12 14.
• 1332 Wohlkoenig, C., et al. (2017). TR3 is involved in hypoxia-induced apoptosis resistance in lung cancer cells downstream of HIF-1α. Lung Cancer
• 1333 Wong, E., et al. (2017). The multi-level impact of chronic intermittent hypoxia on central auditory processing. NeuroImage 156: 232-239.
• 1334 Worthington, K. S., et al. (2017). Two-photon polymerization for production of human iPSC-derived retinal cell grafts. Acta Biomater 55: 385-395.
• 1335 Wu, J., et al. (2017). Lung protection by inhalation of exogenous solubilized extracellular matrix. PLOS ONE 12(2): e0171165.
• 1336 Wu, J., et al. (2017). The effect of chronic intermittent hypoxia on respiratory sensitivity to morphine in rats. Sleep Breath 21(1): 227-233.
• 1337 Xu, D., et al. (2017). The triterpenoid CDDO-imidazolide ameliorates mouse liver ischemia-reperfusion injury through activating the Nrf2/HO-1 pathway enhanced autophagy. Cell Death and Disease 8(8)
• 1338 Xue, J., et al. (2017). Intermittent Hypoxia and Hypercapnia Accelerate Atherosclerosis, Partially via Trimethylamine-Oxide. Am J Respir Cell Mol Biol 57(5): 581-588.
• 1339 Yada, R. C., et al. (2017). Rhesus Macaque iPSC Generation and Maintenance. Curr Protoc Stem Cell Biol 41: 4A 11 11-14A 11 13.
• 1340 Yang, X., et al. (2017). YAP mediate hypoxia-induced pancreatic cancer cells invasion and migration via promoting survivin expression. Cancer Cell Research 14: 356-361
• 1341 Yonchuk, J. G., et al. (2017). Characterization of the Potent, Selective Nrf2 Activator, 3-(Pyridin-3-Ylsulfonyl)-5-(Trifluoromethyl)-2H-Chromen-2-One, in Cellular and In Vivo Models of Pulmonary Oxidative Stress. J Pharmacol Exp Ther 363(1): 114-125.
• 1342 Yong, K. W., et al. (2017). Assessment of tumourigenic potential in long-term cryopreserved human adipose-derived stem cells. J Tissue Eng Regen Med 11(8): 2217-2226.
• 1343 Yoon, D. W., et al. (2017). Accelerated tumor growth under intermittent hypoxia is associated with hypoxia-inducible factor-1-dependent adaptive responses to hypoxia. Oncotarget
• 1344 Zhang, D., et al. (2017). Integrin alphavbeta5 inhibition protects against ischemia-reperfusion-induced lung injury in an autophagy-dependent manner. Am J Physiol Lung Cell Mol Physiol 313(2): L384-L394.
• 1345 Zhang, Q. Y., et al. (2017). Novel Therapeutic Effects of Leonurine On Ischemic Stroke: New Mechanisms of BBB Integrity. Oxid Med Cell Longev 2017: 7150376.
• 1346 Zhang, W., et al. (2017). Follistatin-like 1 protects against hypoxia-induced pulmonary hypertension in mice. Sci Rep 7: 45820.
• 1347 Zhang, Y., et al. (2017). Nrdp1 increases ischemia induced primary rat cerebral cortical neurons and pheochromocytoma cells apoptosis via downregulation of HIF-1α protein. Frontiers in cellular neuroscience 11: 293
• 1348 Zhao, Y., et al. (2017). GSK-3β inhibition induced neuroprotection, regeneration, and functional recovery after intracerebral hemorrhagic stroke. Cell transplantation 26(3): 395-407
• 1349 Zhou, Y., et al. (2017). Characterization and Standardization of Cultured Cardiac Fibroblasts for Ex Vivo Models of Heart Fibrosis and Heart Ischemia. Tissue Eng Part C Methods 23(7): 422-433.
• 1350 Zhu, Y., et al. (2017). Identification of different macrophage subpopulations with distinct activities in a mouse model of oxygen-induced retinopathy. Int J Mol Med 40(2): 281-292.
• 1351 Zungu-Edmondson, M., et al. (2017). Natural reversal of pulmonary vascular remodeling and right ventricular remodeling in SU5416/hypoxia-treated Sprague-Dawley rats. PLOS ONE 12(8): e0182551.
• 1352 Abdel-Wahab, B. A. and M. M. Abdel-Wahab (2016). Protective effect of resveratrol against chronic intermittent hypoxia-induced spatial memory deficits, hippocampal oxidative DNA damage and increased p47Phox NADPH oxidase expression in young rats. Behav Brain Res 305: 65-75.
• 1353 Agematsu, K., et al. (2016). Hypoxia diminishes the protective function of white-matter astrocytes in the developing brain. J Thorac Cardiovasc Surg 151(1): 265-272 e261-263.
• 1354 Agrawal, R., et al. (2016). Pluripotent and Multipotent Stem Cells Display Distinct Hypoxic miRNA Expression Profiles. PLOS ONE 11(10): e0164976.
• 1355 Ahlfeld, S. K., et al. (2016). Initial Suppression of Transforming Growth Factor-beta Signaling and Loss of TGFBI Causes Early Alveolar Structural Defects Resulting in Bronchopulmonary Dysplasia. Am J Pathol 186(4): 777-793.
• 1356 Al-Assar, O., et al. (2016). The radiosensitizing effects of Nelfinavir on pancreatic cancer with and without pancreatic stellate cells. Radiotherapy and Oncology
• 1357Alhallak, K., et al. (2016). Optical Imaging of Cancer Cell Metabolism in Murine Metastatic Breast Cancer. Clinical and Translational Biophotonics: JM3A. 34
• 1358 Alvarez-Martins, I., et al. (2016). The impact of chronic intermittent hypoxia on hematopoiesis and the bone marrow microenvironment. Pflugers Arch 468(5): 919-932.
• 1359 Anderson, D. E., et al. (2016). Responses to altered oxygen tension are distinct between human stem cells of high and low chondrogenic capacity. Stem Cell Res Ther 7(1): 154.
• 1360 Aranda, J. V., et al. (2016). Pharmacologic synergism of ocular ketorolac and systemic caffeine citrate in rat oxygen-induced retinopathy. Pediatr Res 80(4): 554-565.
• 1361 Aron, N., et al. (2016). Pharmacological Interventions for Vascular Targeting in Retinopathy of Prematurity: An Experimental Study. Indian J Physiol Pharmacol 60(3): 282-290.
• 1362 Bailey, K. M., et al. (2016). Micro-Environmental Stress Induces Src-Dependent Activation of Invadopodia and Cell Migration in Ewing Sarcoma. Neoplasia 18(8): 480-488.
• 1363Bardon-Albaret, A. and E. A. Saillant (2016). Effects of hypoxia and elevated ammonia concentration on the viability of red snapper embryos and early larvae. Aquaculture 459: 148-155
• 1364 Battello, N., et al. (2016). The role of HIF-1 in oncostatin M-dependent metabolic reprogramming of hepatic cells. Cancer Metab 4(1): 3.
• 1365 Bertagnolli, M., et al. (2016). Activation of the cardiac renin–angiotensin system in high oxygen-exposed newborn rats: angiotensin receptor blockade prevents the developmental programming of cardiac dysfunction. Hypertension 67(4): 774-782
• 1366Bhatia, M., et al. (2016). Expression of the thioredoxin system in an in vivo-like cancer cell environment upon auranofin treatment. Eur J Cell Biol 95(10): 378-388
• 1367 Blair, N. P., et al. (2016). The effect of intravitreal vascular endothelial growth factor on inner retinal oxygen delivery and metabolism in rats. Exp Eye Res 143: 141-147.
• 1368 Blum, J. I., et al. (2016). Time-dependent PPARγ modulation of HIF-1α signaling in hypoxic pulmonary artery smooth muscle cells. The American journal of the medical sciences 352(1): 71-79
• 1369 Booze, M. L., et al. (2016). A novel mouse model for the identification of thioredoxin-1 protein interactions. Free Radic Biol Med 99: 533-543.
• 1370 Bryant, A. J., et al. (2016). Endothelial HIF signaling regulates pulmonary fibrosis-associated pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 310(3): L249-262.
• 1371Bryant, A. J., et al. (2016). Translational Research in Acute Lung Injury and Pulmonary Fibrosis: Endothelial HIF signaling regulates pulmonary fibrosis-associated pulmonary hypertension. American Journal of Physiology-Lung Cellular and Molecular Physiology 310(3): L249
• 1372 Bu, P., et al. (2016). A Prolactin Family Paralog Regulates Placental Adaptations to a Physiological Stressor in the Mouse. Biology of reproduction: biolreprod. 115.138032
• 1373 Burnier, L., et al. (2016). Physiological cerebrovascular remodeling in response to chronic mild hypoxia: A role for activated protein C. Exp Neurol 283(Pt A): 396-403.
• 1374 Cai, B., et al. (2016). Neuroglobin Overexpression Inhibits AMPK Signaling and Promotes Cell Anabolism. Mol Neurobiol 53(2): 1254-1265.
• 1375 Chahla, J., et al. (2016). Intra-Articular Cellular Therapy for Osteoarthritis and Focal Cartilage Defects of the Knee: A Systematic Review of the Literature and Study Quality Analysis. J Bone Joint Surg Am 98(18): 1511-1521.
• 1376 Chao, D., et al. (2016). Attenuating Ischemic Disruption of K(+) Homeostasis in the Cortex of Hypoxic-Ischemic Neonatal Rats: DOR Activation vs. Acupuncture Treatment. Mol Neurobiol 53(10): 7213-7227.
• 1377 Chen, T., et al. (2016). miR‐17/20 Controls Prolyl Hydroxylase 2 (PHD2)/Hypoxia‐Inducible Factor 1 (HIF1) to Regulate Pulmonary Artery Smooth Muscle Cell Proliferation. Journal of the American Heart Association 5(12).
• 1378 Chen, Y., et al. (2016). Tyrosine kinase receptor EGFR regulates the switch in cancer cells between cell survival and cell death induced by autophagy in hypoxia. Autophagy 12(6): 1029-1046.
• 1379 Cheng, Y., et al. (2016). Induction of Connective Tissue Growth Factor Expression by Hypoxia in Human Lung Fibroblasts via the MEKK1/MEK1/ERK1/GLI-1/GLI-2 and AP-1 Pathways. PLOS ONE 11(8): e0160593.
• 1380 Choi, J. H., et al. (2016). Hypoxia inducible factor-1α regulates the migration of bone marrow mesenchymal stem cells via integrin α4. Stem Cells International 2016
• 1381 Chopra, S., et al. (2016). Sleep Apnea Research in Animals. Past, Present, and Future. Am J Respir Cell Mol Biol 54(3): 299-305.
• 1382 Chou, H. C., et al. (2016). Human mesenchymal stem cells attenuate experimental bronchopulmonary dysplasia induced by perinatal inflammation and hyperoxia. Am J Transl Res 8(2): 342-353.
• 1383 Chua, S. K., et al. (2016). Tumor Necrosis Factor-Alpha and the ERK Pathway Drive Chemerin Expression in Response to Hypoxia in Cultured Human Coronary Artery Endothelial Cells. PLOS ONE 11(10): e0165613.
• 1384 Cikla, U., et al. (2016). Suppression of microglia activation after hypoxia–ischemia results in age-dependent improvements in neurologic injury. Journal of Neuroimmunology 291: 18-27
• 1385 Clermont, A., et al. (2016). Plasma Kallikrein Mediates Vascular Endothelial Growth Factor–Induced Retinal Dysfunction and ThickeningRole of Plasma Kallikrein in VEGF-Induced Retinal Edema. Investigative Ophthalmology & Visual Science 57(6): 2390-2399
• 1386 Cole, M. A., et al. (2016). On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury. The FASEB Journal 30(8): 2684-2697
• 1387 Collet, G., et al. (2016). Endothelial precursor cell-based therapy to target the pathologic angiogenesis and compensate tumor hypoxia. Cancer Lett 370(2): 345-357.
• 1388 Cui, T. X., et al. (2016). Hyperoxic Exposure of Immature Mice Increases the Inflammatory Response to Subsequent Rhinovirus Infection: Association with Danger Signals. J Immunol 196(11): 4692-4705.
• 1389 Cunningham, K. F., et al. (2016). Increased expression of estrogen-related receptor beta during adaptation of adult cardiomyocytes to sustained hypoxia. Am J Cardiovasc Dis 6(2): 46-54.
• 1390 Das, A. M., et al. (2016). Melanomas prevent endothelial cell death under restrictive culture conditions by signaling through AKT and p38 MAPK/ERK-1/2 cascades. Oncoimmunology 5(10): e1219826
• 1391 Datta, R., et al. (2016). Label-free imaging of metabolism and oxidative stress in human induced pluripotent stem cell-derived cardiomyocytes. Biomed Opt Express 7(5): 1690-1701.
• 1392 Davies, T. G., et al. (2016). Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1: NRF2) Protein–Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery. Journal of medicinal chemistry 59(8): 3991-4006
• 1393 DeLuca, A. P., et al. (2016). Hypomorphic mutations in TRNT1 cause retinitis pigmentosa with erythrocytic microcytosis. Hum Mol Genet 25(1): 44-56.
• 1394 Desai, R. A., et al. (2016). Cause and prevention of demyelination in a model multiple sclerosis lesion. Ann Neurol 79(4): 591-604.
• 1395 Detweiler, N. D., et al. (2016). BK Channels in Rat and Human Pulmonary Smooth Muscle Cells are BK-1 Functional Complexes Lacking the Oxygen-Sensitive STREX Insert. Pulmonary Circulation
• 1396 Dhawan, A., et al. (2016). Breast cancer cells compete with hematopoietic stem and progenitor cells for intercellular adhesion molecule 1-mediated binding to the bone marrow microenvironment. Carcinogenesis 37(8): 759-767.
• 1397 Diaz-Trelles, R., et al. (2016). Notch-independent RBPJ controls angiogenesis in the adult heart. Nat Commun 7: 12088.
• 1398 Dinu, D., et al. (2016). Mechanistic role of cytochrome P450 (CYP)1B1 in oxygen-mediated toxicity in pulmonary cells: A novel target for prevention of hyperoxic lung injury. Biochem Biophys Res Commun 476(4): 346-351.
• 1399 Divoky, V., et al. (2016). Delayed hemoglobin switching and perinatal neocytolysis in mice with gain-of-function erythropoietin receptor. J Mol Med (Berl) 94(5): 597-608.
• 1400 Dong, H., et al. (2016). Breast Cancer MDA-MB-231 Cells Use Secreted Heat Shock Protein-90alpha (Hsp90alpha) to Survive a Hostile Hypoxic Environment. Sci Rep 6: 20605.
• 1401 DuBois, J. C., et al. (2016). Yeast Transcriptome and In Vivo Hypoxia Detection Reveals Histoplasma capsulatum Response to Low Oxygen Tension. Med Mycol 54(1): 40-58.
• 1402Dyugovskaya, L., et al. (2016). Intermittent hypoxia affects the spontaneous differentiation in vitro of human neutrophils into long-lived giant phagocytes. Oxidative Medicine and Cellular Longevity 2016
• 1403 Emin, M., et al. (2016). Increased internalization of complement inhibitor CD59 may contribute to endothelial inflammation in obstructive sleep apnea. Sci Transl Med 8(320): 320ra321.
• 1404Ernawati, T., et al. (2016). Hypoxic Preconditioning Improved Neuroprotective Effect of Bone Marrow-Mesenchymal Stem Cells Transplantation in Acute Glaucoma Models. Journal of Biomedical Science and Engineering 9(04): 245
• 1405 Esen, N., et al. (2016). Endogenous adaptation to low oxygen modulates T-cell regulatory pathways in EAE. J Neuroinflammation 13(1): 13.
• 1406 Foldager, C. B., et al. (2016). Collagen Type IV and Laminin Expressions during Cartilage Repair and in Late Clinically Failed Repair Tissues from Human Subjects. Cartilage 7(1): 52-61.
• 1407 Friedman, G. K., et al. (2016). Pediatric medulloblastoma xenografts including molecular subgroup 3 and CD133+ and CD15+ cells are sensitive to killing by oncolytic herpes simplex viruses. Neuro Oncol 18(2): 227-235.
• 1408 Galam, L., et al. (2016). Deletion of P2X7 attenuates hyperoxia-induced acute lung injury via inflammasome suppression. Am J Physiol Lung Cell Mol Physiol 310(6): L572-581.
• 1409 Gammons, M. V. and D. O. Bates (2016). Models of Oxygen Induced Retinopathy in Rodents. Methods Mol Biol 1430: 317-332.
• 1410 Gao, X., et al. (2016). Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia. Nature communications 7
• 1411 Garvey, C. M., et al. (2016). A high-content image-based method for quantitatively studying context-dependent cell population dynamics. Sci Rep 6: 29752.
• 1412 Geng, Y., et al. (2016). Identification of crucial microRNAs and genes in hypoxia-induced human lung adenocarcinoma cells. Onco Targets Ther 9: 4605-4616.
• 1413 Giacalone, J. C., et al. (2016). Concise Review: Patient-Specific Stem Cells to Interrogate Inherited Eye Disease. Stem Cells Transl Med 5(2): 132-140.
• 1414 Gidlöf, O., et al. (2016). Ischemic Preconditioning Confers Epigenetic Repression of Mtor and Induction of Autophagy Through G9a‐Dependent H3K9 Dimethylation. Journal of the American Heart Association 5(12): e004076
• 1415 Gleixner, E., et al. (2016). Knockdown of Drosophila hemoglobin suggests a role in O2 homeostasis. Insect Biochem Mol Biol 72: 20-30.
• 1416 Go, H., et al. (2016). MiR-196a regulates heme oxygenase-1 by silencing Bach1 in the neonatal mouse lung. Am J Physiol Lung Cell Mol Physiol 311(2): L400-411.
• 1417 Goey, A. K., et al. (2016). Screening and Biological Effects of Marine Pyrroloiminoquinone Alkaloids: Potential Inhibitors of the HIF-1α/p300 Interaction. Journal of natural products
• 1418 Gomez Perdiguero, E., et al. (2016). ANGPTL4–αvβ3 interaction counteracts hypoxia‐induced vascular permeability by modulating Src signalling downstream of vascular endothelial growth factor receptor 2. The Journal of pathology 240(4): 461-471
• 1419 Hammoud, A. A., et al. (2016). Murine Embryonic Stem Cell Plasticity Is Regulated through Klf5 and Maintained by Metalloproteinase MMP1 and Hypoxia. PLOS ONE 11(1): e0146281.
• 1420 Han, J., et al. (2016). Photosensitizer-Conjugated Hyaluronic Acid-Shielded Polydopamine Nanoparticles for Targeted Photo-mediated Tumor Therapy. ACS Applied Materials & Interfaces
• 1421 Heikal, L., et al. (2016). Erythropoietin and a nonerythropoietic peptide analog promote aortic endothelial cell repair under hypoxic conditions: role of nitric oxide. Hypoxia (Auckl) 4: 121-133.
• 1422 Helenius, I. T., et al. (2016). Focused Screening Identifies Evoxine as a Small Molecule That Counteracts CO2-Induced Immune Suppression. J Biomol Screen 21(4): 363-371.
• 1423 Helenius, I. T., et al. (2016). Identification of Drosophila Zfh2 as a mediator of hypercapnic immune regulation by a genome-wide RNA interference screen. The Journal of Immunology 196(2): 655-667
• 1424 Hoeber, D., et al. (2016). Erythropoietin Restores Long-Term Neurocognitive Function Involving Mechanisms of Neuronal Plasticity in a Model of Hyperoxia-Induced Preterm Brain Injury. Oxid Med Cell Longev 2016: 9247493.
• 1425 Hofig, I., et al. (2016). p53-Dependent Senescence in Mesenchymal Stem Cells under Chronic Normoxia Is Potentiated by Low-Dose gamma-Irradiation. Stem Cells Int 2016: 6429853.
• 1426 Hoppe, G., et al. (2016). Comparative systems pharmacology of HIF stabilization in the prevention of retinopathy of prematurity. Proc Natl Acad Sci U S A 113(18): E2516-2525.
• 1427 Horii, M., et al. (2016). Human pluripotent stem cells as a model of trophoblast differentiation in both normal development and disease. Proc Natl Acad Sci U S A 113(27): E3882-3891.
• 1428 Hou, J.-Y., et al. (2016). Protective effect of hyperoside on cardiac ischemia reperfusion injury through inhibition of ER stress and activation of Nrf2 signaling. Asian Pacific Journal of Tropical Medicine 9(1): 76-80
• 1429 Houssaini, A., et al. (2016). Selective Tuberous Sclerosis Complex 1 Gene Deletion in Smooth Muscle Activates Mammalian Target of Rapamycin Signaling and Induces Pulmonary Hypertension. Am J Respir Cell Mol Biol 55(3): 352-367.
• 1430 Howell, K. R. and A. Pillai (2016). Long-Term Effects of Prenatal Hypoxia on Schizophrenia-Like Phenotype in Heterozygous Reeler Mice. Mol Neurobiol 53(5): 3267-3276.
• 1431 Hu, J., et al. (2016). Targeting TRAF3 signaling protects against hepatic ischemia/reperfusions injury. J Hepatol 64(1): 146-159.
• 1432 Hu, X., et al. (2016). A Large-Scale Investigation of Hypoxia-Preconditioned Allogeneic Mesenchymal Stem Cells for Myocardial Repair in Non-Human Primates: Paracrine Activity Without Remuscularization. Circulation research: CIRCRESAHA. 115.307516
• 1433 Hu, X., et al. (2016). MiR-211/STAT5A Signaling Modulates Migration of Mesenchymal Stem Cells to Improve its Therapeutic Efficacy. Stem Cells 34(7): 1846-1858.
• 1434 Hua, Y., et al. (2016). MMP-2 Is Mainly Expressed in Arterioles and Contributes to Cerebral Vascular Remodeling Associated with TGF-beta1 Signaling. J Mol Neurosci 59(3): 317-325.
• 1435 Hua-Huy, T., et al. (2016). Inhaled nitric oxide decreases pulmonary endothelial nitric oxide synthase expression and activity in normal newborn rat lungs. ERJ Open Res 2(1): 00060-02015.
• 1436 Huetsch, J. C., et al. (2016). The Na+/H+ exchanger contributes to increased smooth muscle proliferation and migration in a rat model of pulmonary arterial hypertension. Physiol Rep 4(5): e12729.
• 1437 Huynh, L., et al. (2016). Opposing regulation of the late phase TNF response by mTORC1-IL-10 signaling and hypoxia in human macrophages. Sci Rep 6: 31959.
• 1438 Jameson, H., et al. (2016). Oxytocin neuron activation prevents hypertension that occurs with chronic intermittent hypoxia/hypercapnia in rats. American Journal of Physiology-Heart and Circulatory Physiology: ajpheart. 00808.02015
• 1439 Jiwon, S. and R. M. Jeffrey (2016). Economic 3D-printing approach for transplantation of human stem cell-derived β -like cells. Biofabrication 9(1): 015002.
• 1440 Jürgen, G., et al. (2016). Biofabrication: reappraising the definition of an evolving field. Biofabrication 8(1): 013001.
• 1441 Kapitsinou, P. P., et al. (2016). The Endothelial Prolyl-4-Hydroxylase Domain 2/Hypoxia-Inducible Factor 2 Axis Regulates Pulmonary Artery Pressure in Mice. Mol Cell Biol 36(10): 1584-1594.
• 1442 Kessel, D. and C. L. Evans (2016). Promotion of Proapoptotic Signals by Lysosomal Photodamage: Mechanistic Aspects and Influence of Autophagy. Photochem Photobiol 92(4): 620-623.
• 1443 Kim, C., et al. (2016). The alternative complement pathway aids in vascular regression during the early stages of a murine model of proliferative retinopathy. FASEB J 30(3): 1300-1305.
• 1444 Kim, H. J. and H. Y. Yoo (2016). Hypoxic pulmonary vasoconstriction and vascular contractility in monocrotaline-induced pulmonary arterial hypertensive rats. Korean J Physiol Pharmacol 20(6): 641-647.
• 1445 Kim, Y., et al. (2016). Methylation-dependent regulation of HIF-1alpha stability restricts retinal and tumour angiogenesis. Nat Commun 7: 10347.
• 1446 Kimura, K. and R. C. Huang (2016). Tetra-O-Methyl Nordihydroguaiaretic Acid Broadly Suppresses Cancer Metabolism and Synergistically Induces Strong Anticancer Activity in Combination with Etoposide, Rapamycin and UCN-01. PLOS ONE 11(2): e0148685.
• 1447 Kobayashi, H., et al. (2016). Distinct subpopulations of FOXD1 stroma-derived cells regulate renal erythropoietin. J Clin Invest 126(5): 1926-1938.
• 1448Konsavage, W., et al. (2016). Maintenance of Feeding-Induced Translation Initiation Complex Assembly in the Lungs of Hyperoxia-Exposed Newborn Rats. Pediatr Neonatal Nurs Open Access 2(3): 2470-0983.2114
• 1449 Kossatz, E., et al. (2016). CB2 cannabinoid receptors modulate HIF-1α and TIM-3 expression in a hypoxia-ischemia mouse model. European Neuropsychopharmacology 26(12): 1972-1988
• 1450 Kovacs, L., et al. (2016). Activation of Calpain-2 by Mediators in Pulmonary Vascular Remodeling of Pulmonary Arterial Hypertension. Am J Respir Cell Mol Biol 54(3): 384-393.
• 1451 Krause, B. J., et al. (2016). Arginase-2 is cooperatively up-regulated by nitric oxide and histone deacetylase inhibition in human umbilical artery endothelial cells. Biochemical pharmacology 99: 53-59
• 1452 Ku, J. M., et al. (2016). Characterisation of a mouse cerebral microvascular endothelial cell line (bEnd.3) after oxygen glucose deprivation and reoxygenation. Clin Exp Pharmacol Physiol 43(8): 777-786.
• 1453 Kudryashova, T. V., et al. (2016). HIPPO-integrin Linked Kinase Crosstalk Controls Self-sustaining Proliferation and Survival in Pulmonary Hypertension. American journal of respiratory and critical care medicine(ja)
• 1454 Kumar, V., et al. (2016). CD45 Phosphatase Inhibits STAT3 Transcription Factor Activity in Myeloid Cells and Promotes Tumor-Associated Macrophage Differentiation. Immunity 44(2): 303-315.
• 1455 Kvarik, T., et al. (2016). PACAP is protective in a rat model of retinopathy of prematurity. Journal of Molecular Neuroscience 60(2): 179-185
• 1456 Lai, K., et al. (2016). Regulation of angiogenin expression and epithelial-mesenchymal transition by HIF-1α signaling in hypoxic retinal pigment epithelial cells. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease
• 1457 Lajko, M., et al. (2016). Hyperoxia-Induced Proliferative Retinopathy: Early Interruption of Retinal Vascular Development with Severe and Irreversible Neurovascular Disruption. PLOS ONE 11(11): e0166886.
• 1458 Leca, J., et al. (2016). Cancer-associated fibroblast-derived annexin A6+ extracellular vesicles support pancreatic cancer aggressiveness. J Clin Invest 126(11): 4140-4156.
• 1459 Lee, M. Y., et al. (2016). Intermittent hypoxia induces NF-kappaB-dependent endothelial activation via adipocyte-derived mediators. Am J Physiol Cell Physiol 310(6): C446-455.
• 1460 Lee, W.-H., et al. (2016). Mouse Tmem135 mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologies. eLife 5: e19264
• 1461 Leithner, K., et al. (2016). TASK-1 Regulates Apoptosis and Proliferation in a Subset of Non-Small Cell Lung Cancers. PLOS ONE 11(6): e0157453.
• 1462 Lewis, D. M., et al. (2016). Intratumoral oxygen gradients mediate sarcoma cell invasion. Proc Natl Acad Sci U S A 113(33): 9292-9297.
• 1463 Li, P., et al. (2016). Effects and relationship of intermittent hypoxia on serum lipid levels, hepatic low-density lipoprotein receptor-related protein 1, and hypoxia-inducible factor 1alpha. Sleep Breath 20(1): 167-173.
• 1464 Li, X., et al. (2016). KLF5 mediates vascular remodeling via HIF-1α in hypoxic pulmonary hypertension. American Journal of Physiology-Lung Cellular and Molecular Physiology 310(4): L299-L310
• 1465 Li, X., et al. (2016). MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features. Oncotarget 7(26): 40297-40313.
• 1466 Liu, C. H., et al. (2016). Peroxiredoxin 1 induces inflammatory cytokine response and predicts outcome of cardiogenic shock patients necessitating extracorporeal membrane oxygenation: an observational cohort study and translational approach. J Transl Med 14(1): 114.
• 1467 Liu, Z., et al. (2016). EGFRvIII/integrin β3 interaction in hypoxic and vitronectinenriching microenvironment promote GBM progression and metastasis. Oncotarget 7(4): 4680
• 1468 Logan, S., et al. (2016). Chronic intermittent hyperoxia alters the development of the hypoxic ventilatory response in neonatal rats. Respir Physiol Neurobiol 220: 69-80.
• 1469 Lopez, N. C., et al. (2016). Role of the RhoA/ROCK pathway in high-altitude associated neonatal pulmonary hypertension in lambs. Am J Physiol Regul Integr Comp Physiol 310(11): R1053-1063.
• 1470 Luangphakdy, V., et al. (2016). Assessment of Methods for Rapid Intraoperative Concentration and Selection of Marrow-Derived Connective Tissue Progenitors for Bone Regeneration Using the Canine Femoral Multidefect Model. Tissue Eng Part A 22(1-2): 17-30.
• 1471 Luo, D., et al. (2016). Plant-derived triterpene celastrol ameliorates oxygen glucose deprivation-induced disruption of endothelial barrier assembly via inducing tight junction proteins. Phytomedicine 23(13): 1621-1628.
• 1472 Lv, X., et al. (2016). Structural and functional evaluation of oxygenating keratin/silk fibroin scaffold and initial assessment of their potential for urethral tissue engineering. Biomaterials 84: 99-110.
• 1473Lv, X.-l., et al. (2016). Neurotherapeutic effect of mangiferin against hypoxic–ischemic encephalopathy in neonatal rats. African Journal of Traditional, Complementary and Alternative Medicines 13(2): 229-236
• 1474 Ma, X., et al. (2016). The pancreatic cancer secreted REG4 promotes macrophage polarization to M2 through EGFR/AKT/CREB pathway. Oncology reports 35(1): 189-196
• 1475 Mansor, L. S., et al. (2016). Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation. J Physiol 594(2): 307-320.
• 1476 Marco, I., et al. (2016). Degradation testing of Mg alloys in Dulbecco’s modified eagle medium: Influence of medium sterilization. Materials Science and Engineering: C
• 1477 Markway, B. D., et al. (2016). Reoxygenation enhances tumour necrosis factor alpha-induced degradation of the extracellular matrix produced by chondrogenic cells. Eur Cell Mater 31: 425-439.
• 1478 McDonald, F. B., et al. (2016). Early Life Exposure to Chronic Intermittent Hypoxia Primes Increased Susceptibility to Hypoxia-Induced Weakness in Rat Sternohyoid Muscle during Adulthood. Front Physiol 7: 69.
• 1479 McDonald, F. B., et al. (2016). Effects of Gestational and Postnatal Exposure to Chronic Intermittent Hypoxia on Diaphragm Muscle Contractile Function in the Rat. Front Physiol 7: 276.
• 1480 Mei, X., et al. (2016). The Thioredoxin Encoded by the Rod-Derived Cone Viability Factor Gene Protects Cone Photoreceptors Against Oxidative Stress. Antioxid Redox Signal 24(16): 909-923.
• 1481 Mezu-Ndubuisi, O. J. (2016). In Vivo Angiography Quantifies Oxygen-Induced Retinopathy Vascular Recovery. Optom Vis Sci 93(10): 1268-1279.
• 1482 Michaloski, J. S., et al. (2016). Discovery of pan-VEGF inhibitory peptides directed to the extracellular ligand-binding domains of the VEGF receptors. Sci Adv 2(10): e1600611.
• 1483 Milash, B., et al. (2016). Temporal Dysynchrony in brain connectivity gene expression following hypoxia. BMC genomics 17(1): 334.
• 1484Mingming, Z., et al. (2016). GW27-e0037 Notch3/Akt Signaling Contributes to OSM-Induced Protection against Cardiac Ischemia/Reperfusion Injury. Journal of the American College of Cardiology 68(16): C2
• 1485 Mistry, R. K., et al. (2016). Transcriptional regulation of cystathionine-γ-lyase in endothelial cells by NADPH oxidase 4-dependent signaling. Journal of Biological Chemistry 291(4): 1774-1788
• 1486 Mizuuchi, M., et al. (2016). Placental endoplasmic reticulum stress negatively regulates transcription of placental growth factor via ATF4 and ATF6β: implications for the pathophysiology of human pregnancy complications. The Journal of pathology 238(4): 550-561
• 1487 Mondal, A., et al. (2016). IDO1 is an Integral Mediator of Inflammatory Neovascularization. EBioMedicine
• 1488 Morita, A., et al. (2016). Exposure to high-concentration oxygen in the neonatal period induces abnormal retinal vascular patterning in mice. Birth Defects Res B Dev Reprod Toxicol 107(6): 216-224.
• 1489 Mumaw, C. L., et al. (2016). Microglial priming through the lung–brain axis: the role of air pollution–induced circulating factors. The FASEB Journal: fj. 201500047
• 1490Murakami, Y., et al. (2016). Exposure to Mild Hypoxia Associated with Oral Breathing Affects The NK Cell Ratio in The Spleen. International Journal of Oral-Medical Sciences 14(4): 67-73
• 1491 Nam, H., et al. (2016). Synergistic Inhibitory Effects of Hypoxia and Iron Deficiency on Hepatic Glucose Response in Mouse Liver. Diabetes 65(6): 1521-1533.
• 1492 Namba, F., et al. (2016). Sex-related differences in long-term pulmonary outcomes of neonatal hyperoxia in mice. Exp Lung Res 42(2): 57-65.
• 1493 Nguyen, D. D., et al. (2016). Modulation of Muscle Fiber Compositions in Response to Hypoxia via Pyruvate Dehydrogenase Kinase-1. Front Physiol 7: 604.
• 1494 Nuschke, A., et al. (2016). Mesenchymal stem cells/multipotent stromal cells (MSCs) are glycolytic and thus glucose is a limiting factor of in vitro models of MSC starvation. Stem Cell Res Ther 7(1): 179.
• 1495 O’Neill, C. L., et al. (2016). Endothelial cell-derived pentraxin 3 limits the vasoreparative therapeutic potential of circulating angiogenic cells. Cardiovascular research: cvw209
• 1496 Orue, A., et al. (2016). Hypoxic resistance of KRAS mutant tumor cells to 3-Bromopyruvate is counteracted by Prima-1 and reversed by N-acetylcysteine. BMC cancer 16(1): 902.
• 1497 Page, S., et al. (2016). Cerebral hypoxia/ischemia selectively disrupts tight junctions complexes in stem cell-derived human brain microvascular endothelial cells. Fluids Barriers CNS 13(1): 16.
• 1498 Pan, Y.-Y., et al. (2016). Altered Wnt Signaling Pathway in Cognitive Impairment Caused by Chronic Intermittent Hypoxia: Focus on Glycogen Synthase Kinase-3β and β-catenin. Chinese medical journal 129(7): 838
• 1499 Panchanathan, R., et al. (2016). Hypoxia primes human normal prostate epithelial cells and cancer cell lines for the NLRP3 and AIM2 inflammasome activation. Oncotarget 7(19): 28183-28194.
• 1500 Park, E. C. and C. Rongo (2016). The p38 MAP kinase pathway modulates the hypoxia response and glutamate receptor trafficking in aging neurons. eLife 5.
• 1501 Park, W., et al. (2016). A highly tumor-specific light-triggerable drug carrier responds to hypoxic tumor conditions for effective tumor treatment. Biomaterials 77: 227-234.
• 1502 Patel, V. S., et al. (2016). Ascorbic Acid Attenuates Hyperoxia-Compromised Host Defense against Pulmonary Bacterial Infection. Am J Respir Cell Mol Biol 55(4): 511-520.
• 1503 Pereboeva, L., et al. (2016). Robust DNA Damage Response and Elevated Reactive Oxygen Species in TINF2-Mutated Dyskeratosis Congenita Cells. PLOS ONE 11(2): e0148793.
• 1504 Poon, A. W., et al. (2016). Impact of bronchopulmonary dysplasia on brain and retina. Biol Open 5(4): 475-483.
• 1505 Przygodda, F., et al. (2016). Acute intermittent hypoxia in rats activates muscle proteolytic pathways through a glucocorticoid-dependent mechanism. Journal of Applied Physiology: jap. 00977.02015
• 1506 Puro, D. G., et al. (2016). Bioelectric impact of pathological angiogenesis on vascular function. Proc Natl Acad Sci U S A 113(35): 9934-9939.
• 1507 Racca, A. C., et al. (2016). Low oxygen tension induces Kruppel-Like Factor 6 expression in trophoblast cells. Placenta 45: 50-57.
• 1508 Ravikumar, P., et al. (2016). Nanoparticle facilitated inhalational delivery of erythropoietin receptor cDNA protects against hyperoxic lung injury. Nanomedicine 12(3): 811-821.
• 1509 Reinboth, B. S., et al. (2016). Endogenous hypothermic response to hypoxia reduces brain injury: Implications for modeling hypoxic-ischemic encephalopathy and therapeutic hypothermia in neonatal mice. Exp Neurol 283(Pt A): 264-275.
• 1510 Reis, M., et al. (2016). Recent Developments in Cellular Immunotherapy for HSCT-Associated Complications. Front Immunol 7(500): 500.
• 1511 Rumsey, W. L., et al. (2016). Effects of airborne toxicants on pulmonary function and mitochondrial DNA damage in rodent lungs. Mutagenesis: gew063
• 1512 Russo, M. A., et al. (2016). Hypoxia and Inflammation in Prostate Cancer Progression. Cross-talk with Androgen and Estrogen Receptors and Cancer Stem Cells. Endocr Metab Immune Disord Drug Targets 16(4): 235-248.
• 1513 Sacramento, J., et al. (2016). Insulin resistance is associated with tissue-specific regulation of HIF-1α and HIF-2α during mild chronic intermittent hypoxia. Respiratory physiology & neurobiology 228: 30-38
• 1514 Schreiber-Brynzak, E., et al. (2016). Behavior of platinum(iv) complexes in models of tumor hypoxia: cytotoxicity, compound distribution and accumulation. Metallomics 8(4): 422-433.
• 1515 Seedorf, G. J., et al. (2016). Hepatocyte Growth Factor as a Downstream Mediator of Vascular Endothelial Growth Factor-Dependent Preservation of Growth in the Developing Lung. American Journal of Physiology-Lung Cellular and Molecular Physiology: ajplung. 00423.02015
• 1516 Sengoku, T., et al. (2016). Neonatal hyperoxia induces alterations in neurotrophin gene expression. Int J Dev Neurosci 48: 31-37.
• 1517 Sengupta, S., et al. (2016). The circadian gene Rev-erbα improves cellular bioenergetics and provides preconditioning for protection against oxidative stress. Free Radical Biology and Medicine 93: 177-189
• 1518 Serdar, M., et al. (2016). Fingolimod protects against neonatal white matter damage and long-term cognitive deficits caused by hyperoxia. Brain Behav Immun 52: 106-119.
• 1519 Shafiee, A., et al. (2016). Evaluation and comparison of the in vitro characteristics and chondrogenic capacity of four adult stem/progenitor cells for cartilage cell-based repair. J Biomed Mater Res A 104(3): 600-610.
• 1520Shanshan, L. and Y. Zhu (2016). GW27-e0039 ZYZ-168 alleviates myocardial infarction induced cardiac fibrosis through inhibition of ERK-dependent ROCK1 activation. Journal of the American College of Cardiology 68(16): C2
• 1521 Shen, Y., et al. (2016). Effect of cytokeratin 17 on retinal pigment epithelium degeneration and choroidal neovascularization. Int J Ophthalmol 9(3): 363-368.
• 1522Sherwood, J. W., et al. (2016). Chronic Exposure to Elevated Ambient CO2 Influences the Orexinergic System in the Lateral Hypothalamus and Dorsocaudal Medulla. The FASEB Journal 30(1 Supplement): 772.779-772.779
• 1523 Shi, L., et al. (2016). miR-223–IGF-IR signaling in hypoxia-and load-induced right ventricular failure: a novel therapeutic approach. Cardiovascular research: cvw065
• 1524 Shi, T., et al. (2016). α 1A-Adrenergic receptor prevents cardiac ischemic damage through PKC δ/GLUT1/4-mediated glucose uptake. Journal of Receptors and Signal Transduction 36(3): 261-270
• 1525 Siemerink, M. J., et al. (2016). CD34 Promotes Pathological Epi-Retinal Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy. PLOS ONE 11(6): e0157902
• 1526 Singh, P., et al. (2016). GRK5 deficiency leads to susceptibility to intermittent hypoxia-induced cognitive impairment. Behav Brain Res 302: 29-34.
• 1527 Singh, S., et al. (2016). Stem Cells in Neurotoxicology/Developmental Neurotoxicology: Current Scenario and Future Prospects. Mol Neurobiol 53(10): 6938-6949.
• 1528 Siwetz, M., et al. (2016). TNF-alpha alters the inflammatory secretion profile of human first trimester placenta. Lab Invest 96(4): 428-438.
• 1529 Spix, N. J., et al. (2016). Vulnerability of Dopaminergic Amacrine Cells to Chronic Ischemia in a Mouse Model of Oxygen-Induced RetinopathyLoss of Dopaminergic Amacrine Cells in OIR. Investigative Ophthalmology & Visual Science 57(7): 3047-3057
• 1530 Srivastava, I. N., et al. (2016). mTOR pathway inhibition prevents neuroinflammation and neuronal death in a mouse model of cerebral palsy. Neurobiol Dis 85: 144-154.
• 1531 Stelter, Z., et al. (2016). Hypoxia-induced cardiac injury in dystrophic mice. Am J Physiol Heart Circ Physiol 310(7): H938-948.
• 1532 Stover, A. E., et al. (2016). Culturing Human Pluripotent and Neural Stem Cells in an Enclosed Cell Culture System for Basic and Preclinical Research. J Vis Exp(112).
• 1533 Strasser, K., et al. (2016). Dose-dependent effects of levetiracetam after hypoxia and hypothermia in the neonatal mouse brain. Brain Res 1646: 116-124.
• 1534 Sun, Y. W., et al. (2016). CK0403, a 9‑aminoacridine, is a potent anti‑cancer agent in human breast cancer cells. Molecular medicine reports 13(1): 933-938
• 1535 Sunderram, J., et al. (2016). Heme oxygenase-1-dependent central cardiorespiratory adaptations to chronic intermittent hypoxia in mice. J Appl Physiol (1985) 121(4): 944-952.
• 1536 Sutherland, M. R., et al. (2016). Age- and sex-related changes in rat renal function and pathology following neonatal hyperoxia exposure. Physiol Rep 4(15): e12887.
• 1537 Tafreshi, N. K., et al. (2016). Evaluation of CAIX and CAXII expression in breast cancer at varied O 2 levels: CAIX is the superior surrogate imaging biomarker of tumor hypoxia. Molecular Imaging and Biology 18(2): 219-231
• 1538 Tan, F., et al. (2016). Original Research: Diametric effects of hypoxia on pathophysiology of sickle cell disease in a murine model. Exp Biol Med (Maywood) 241(7): 766-771.
• 1539 Tang, X., et al. (2016). CLOCK Promotes Endothelial Damage by Inducing Autophagy through Reactive Oxygen Species. Oxidative Medicine and Cellular Longevity 2016
• 1540 Tanimoto, N., et al. (2016). Differentiation of murine models of “negative ERG” by single and repetitive light stimuli. Doc Ophthalmol 132(2): 101-109.
• 1541 Tiwari, A., et al. (2016). Impact of Oxygen Levels on Human Hematopoietic Stem and Progenitor Cell Expansion. Stem Cells Dev 25(20): 1604-1613.
• 1542 Tuomela, J. M., et al. (2016). Telomeric G-quadruplex-forming DNA fragments induce TLR9-mediated and LL-37-regulated invasion in breast cancer cells in vitro. Breast Cancer Res Treat 155(2): 261-271.
• 1543 Uddin, M. I., et al. (2016). In Vivo Imaging of Retinal Hypoxia in a Model of Oxygen-Induced Retinopathy. Sci Rep 6: 31011.
• 1544 Ulbrich, F., et al. (2016). Propofol, but not ketamine or midazolam, exerts neuroprotection after ischaemic injury by inhibition of Toll-like receptor 4 and nuclear factor kappa-light-chain-enhancer of activated B-cell signalling: A combined in vitro and animal study. European Journal of Anaesthesiology (EJA) 33(9): 670-680
• 1545 Vasilevskaya, I. A., et al. (2016). JNK1 Inhibition Attenuates Hypoxia-Induced Autophagy and Sensitizes to Chemotherapy. Mol Cancer Res 14(8): 753-763.
• 1546 Vecchio, E. A., et al. (2016). Ligand-independent adenosine A2B receptor constitutive activity as a promoter of prostate cancer cell proliferation. Journal of Pharmacology and Experimental Therapeutics: jpet. 115.230003
• 1547 Veerappan, A., et al. (2016). Mast cells and exosomes in hyperoxia-induced neonatal lung disease. Am J Physiol Lung Cell Mol Physiol 310(11): L1218-1232.
• 1548 Vera-Cruz, P., et al. (2016). Structure of the rat tracheal mucosa after chronic intermittent hypoxia or chronic hyperbaric oxygen therapy. Histol Histopathol 31(6): 657-662.
• 1549 Visovatti, S. H., et al. (2016). Purinergic dysregulation in pulmonary hypertension. Am J Physiol Heart Circ Physiol 311(1): H286-298.
• 1550Vyas, M., et al. (2016). Hypoxia induced HIF-1 alpha expression promotes angiogenesis, tumor budding cell survival and cell proliferation arrest in highgrade tumor budding colorectal carcinomas. Int J Clin Exp Patho 9: 13047-13055
• 1551 Wan, F., et al. (2016). Extracellular Calpain/Calpastatin Balance is Involved in the Progression of Pulmonary Hypertension. American Journal of Respiratory Cell and Molecular Biology(ja)
• 1552 Wang, H., et al. (2016). Tideglusib, a chemical inhibitor of GSK3β, attenuates hypoxic-ischemic brain injury in neonatal mice. Biochimica et Biophysica Acta (BBA)-General Subjects 1860(10): 2076-2085
• 1553 Wang, L., et al. (2016). Effect of Hypoxia-regulated Polo-like Kinase 3 (Plk3) on Human Limbal Stem Cell Differentiation. J Biol Chem 291(32): 16519-16529.
• 1554 Wang, X., et al. (2016). Carfilzomib reverses pulmonary arterial hypertension. Cardiovasc Res 110(2): 188-199.
• 1555 Wang, X., et al. (2016). Inhibitory effect of TGF-beta peptide antagonist on the fibrotic phenotype of human hypertrophic scar fibroblasts. Pharm Biol 54(7): 1189-1197.
• 1556 Wang, Y., et al. (2016). The Eyes Absent Proteins in Developmental and Pathological Angiogenesis. Am J Pathol 186(3): 568-578.
• 1557 Wei, G. and S. Wen (2016). GW27-e0044 ADRB2 Polymorphisms and Dyslipidemia Risk in Chinese Hypertensive Patients. Journal of the American College of Cardiology 68(16): C2
• 1558 Welser-Alves, J. V., et al. (2016). β4 integrin is not essential for localization of hemidesmosome proteins plectin and CD151 in cerebral vessels. Brain circulation 2(4): 189
• 1559 Werner, F., et al. (2016). Endothelial actions of atrial natriuretic peptide prevent pulmonary hypertension in mice. Basic Res Cardiol 111(2): 22.
• 1560 Wiley, L. A., et al. (2016). cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness. Sci Rep 6: 30742.
• 1561 Wiley, L. A., et al. (2016). Using patient-specific induced pluripotent stem cells and wild-type mice to develop a gene augmentation-based strategy to treat CLN3-associated retinal degeneration. Human gene therapy 27(10): 835-846
• 1562Williams, J. M., et al. (2016). Psg22-null mouse embryos develop normally under normoxic and hypoxic conditions of pregnancy. Matters 2(12): e201611000023
• 1563Wit, J. C., et al. (2016). A SHORT-TERM SURVIVAL EXPERIMENT ASSESSING IMPACTS OF OCEAN ACIDIFICATION AND HYPOXIA ON THE BENTHIC FORAMINIFER GLOBOBULIMINA TURGIDA. The Journal of Foraminiferal Research 46(1): 25-33
• 1564 Worthington, K. S., et al. (2016). Differentiation of Induced Pluripotent Stem Cells to Neural Retinal Precursor Cells on Porous Poly-Lactic-co-Glycolic Acid Scaffolds. J Ocul Pharmacol Ther 32(5): 310-316.
• 1565 Wu, Y., et al. (2016). RSUME is implicated in tumorigenesis and metastasis of pancreatic neuroendocrine tumors. Oncotarget
• 1566 Xie, S., et al. (2016). Chronic intermittent hypoxia induces cardiac hypertrophy by impairing autophagy through the adenosine 5′-monophosphate-activated protein kinase pathway. Archives of Biochemistry and Biophysics 606: 41-52
• 1567 Xu, B., et al. (2016). Neuroprotective Effects of a PSD-95 Inhibitor in Neonatal Hypoxic-Ischemic Brain Injury. Mol Neurobiol 53(9): 5962-5970.
• 1568 Xu, J. C., et al. (2016). Cultured networks of excitatory projection neurons and inhibitory interneurons for studying human cortical neurotoxicity. Sci Transl Med 8(333): 333ra348.
• 1569 Yang, C., et al. (2016). Adropin reduces paracellular permeability of rat brain endothelial cells exposed to ischemia-like conditions. Peptides 81: 29-37.
• 1570 Yang, R., et al. (2016). Transcriptional Profiling Identifies the Signaling Axes of IGF and Transforming Growth Factor-b as Involved in the Pathogenesis of Osteosarcoma. Clin Orthop Relat Res 474(1): 178-189.
• 1571 Yeh, T.-H., et al. (2016). Selective intracellular delivery of recombinant arginine deiminase (ADI) using pH-sensitive cell penetrating peptides to overcome ADI resistance in hypoxic breast cancer cells. Molecular pharmaceutics 13(1): 262-271
• 1572 Yeng, C. H., et al. (2016). Attenuating spinal cord injury by conditioned medium from human umbilical cord blood-derived CD34(+) cells in rats. Taiwan J Obstet Gynecol 55(1): 85-93.
• 1573 Zera, K., et al. (2016). Role of HIF-1α in the hypoxia inducible expression of the thiamine transporter, SLC19A3. Gene 595(2): 212-220
• 1574 Zhang, L., et al. (2016). Hypoxia Created Human Mesenchymal Stem Cell Sheet for Prevascularized 3D Tissue Construction. Adv Healthc Mater 5(3): 342-352.
• 1575 Zhang, S., et al. (2016). Stabilization of Hypoxia-inducible Factor by DMOG Inhibits Development of Chronic Hypoxia–Induced Right Ventricular Remodeling. Journal of cardiovascular pharmacology 67(1): 68-75
• 1576 Zhang, Y. Q., et al. (2016). Delayed reendothelialization with rapamycin is rescued by the addition of nicorandil in balloon-injured rat carotid arteries. Oncotarget 7(46): 75926-75939
• 1577 Zhang, Y., et al. (2016). Cerebral Microvascular Endothelial Cell Apoptosis after Ischemia: Role of Enolase-Phosphatase 1 Activation and Aci-Reductone Dioxygenase 1 Translocation. Front Mol Neurosci 9: 79.
• 1578Zhao, Y., et al. (2016). Nonenzymatic detection of glucose using three-dimensional PtNi nanoclusters electrodeposited on the multiwalled carbon nanotubes. Sensors and Actuators B: Chemical 231: 800-810
• 1579 Zhu, L., et al. (2016). Mitochondrial transplantation attenuates hypoxic pulmonary hypertension. Oncotarget 7(31): 48925-48940.
• 1580 Zimmer, A. D., et al. (2016). Phosphorylation of the pyruvate dehydrogenase complex precedes HIF-1-mediated effects and pyruvate dehydrogenase kinase 1 upregulation during the first hours of hypoxic treatment in hepatocellular carcinoma cells. Hypoxia (Auckl) 4: 135-145.
• 1581 Zungu-Edmondson, M., et al. (2016). Modulators of right ventricular apoptosis and contractility in a rat model of pulmonary hypertension. Cardiovasc Res 110(1): 30-39.
• 1582 Zynda, E. R., et al. (2016). An RNA interference screen identifies new avenues for nephroprotection. Cell Death Differ 23(4): 608-615.
• 1583 Abdalla, M., et al. (2015). Akt inhibitor, triciribine, ameliorates chronic hypoxia‐induced vascular pruning and TGFβ‐induced pulmonary fibrosis. British Journal of Pharmacology
• 1584 Abdelsaid, M., et al. (2015). Metformin treatment in the period after stroke prevents nitrative stress and restores angiogenic signaling in the brain in diabetes. Diabetes 64(5): 1804-1817.
• 1585 Abdul, K. S. M., et al. (2015). Mild hypoxia in vivo regulates cardioprotective SUR2A: A role for Akt and LDH. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease
• 1586 Accorsi-Mendonça, D., et al. (2015). Enhanced Firing in NTS Induced by Short-Term Sustained Hypoxia Is Modulated by Glia-Neuron Interaction. The Journal of Neuroscience 35(17): 6903-6917
• 1587 Agrawal, V., et al. (2015). Potential role of increased oxygenation in altering perinatal adrenal steroidogenesis. Pediatr Res 77(2): 298-309.
• 1588 Ahlfeld, S. K., et al. (2015). Relationship of structural to functional impairment during alveolar-capillary membrane development. Am J Pathol 185(4): 913-919.
• 1589 Ahn, K. C., et al. (2015). Inhibition of p53 attenuates ischemic stress-induced activation of astrocytes. NeuroReport 26(14): 862-869.
• 1590 Ahn, S. H., et al. (2015). Interaction of peroxiredoxin V with dihydrolipoamide branched chain transacylase E2 (DBT) in mouse kidney under hypoxia. Proteome Sci 13(1): 4.
• 1591 Aras, S., et al. (2015). MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism. Mitochondrion 20: 43-51.
• 1592 Arlier, Z., et al. (2015). Hypertension alters phosphorylation of VASP in brain endothelial cells. Int J Neurosci 125(4): 288-297.
• 1593 Baek, K. S., et al. (2015). Immunotoxicological Effects of Aripiprazole: In vivo and In vitro Studies. Korean J Physiol Pharmacol 19(4): 365-372.
• 1594 Baik, S. W., et al. (2015). Effects of Remifentanil Preconditioning on Osteoblasts under Hypoxia-Reoxygenation Condition. Int J Med Sci 12(7): 583-589.
• 1595 Bailey, C. K., et al. (2015). Efficacy of the HSP70 inhibitor PET-16 in multiple myeloma. Cancer Biol Ther 16(9): 1422-1426.
• 1596 Bao, M. W., et al. (2015). Dickkopf-3 protects against cardiac dysfunction and ventricular remodelling following myocardial infarction. Basic Res Cardiol 110(3): 25.
• 1597 Basu, J., et al. (2015). Preclinical biosafety evaluation of cell-based therapies: emerging global paradigms. Toxicol Pathol 43(1): 115-125.
• 1598 Belcastro, R., et al. (2015). Chronic lung injury in the neonatal rat: Up-regulation of TGFβ1 and nitration of IGF-R1 by peroxynitrite as likely contributors to impaired alveologenesis. Free Radical Biology and Medicine 80: 1-11
• 1599 Berghold, V. M., et al. (2015). Phospholipid scramblase 1 (PLSCR1) in villous trophoblast of the human placenta. Histochem Cell Biol 143(4): 381-396.
• 1600 Bertero, T., et al. (2015). Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit. Cell Reports 13(5): 1016-1032.
• 1601 Bertero, T., et al. (2015). The microRNA-130/301 family controls vasoconstriction in pulmonary hypertension. J Biol Chem 290(4): 2069-2085.
• 1602 Bettaga, N., et al. (2015). Cell-specific impact of nitric oxide-dependent guanylyl cyclase on arteriogenesis and angiogenesis in mice. Angiogenesis 18(3): 245-254.
• 1603Bhatti, F., et al. (2015). Pulmonary Surfactant Protein A Is Expressed in Mouse Retina by Müller Cells and Impacts Neovascularization in Oxygen-Induced Retinopathy. Investigative Ophthalmology & Visual Science 56(1): 232-242
• 1604 Biesterveld, B. E., et al. (2015). Intestinal alkaline phosphatase to treat necrotizing enterocolitis. J Surg Res 196(2): 235-240.
• 1605 Binder, U., et al. (2015). Effect of reduced oxygen on the antifungal susceptibility of clinically relevant aspergilli. Antimicrob Agents Chemother 59(3): 1806-1810.
• 1606 Blaschitz, A., et al. (2015). Adhering maternal platelets can contribute to the cytokine and chemokine cocktail released by human first trimester villous placenta. Placenta 36(11): 1333-1336
• 1607 Boroujerdi, A. and R. Milner (2015). Defining the critical hypoxic threshold that promotes vascular remodeling in the brain. Experimental neurology 263: 132-140.
• 1608 Boroujerdi, A., et al. (2015). Matrix metalloproteinase-9 mediates post-hypoxic vascular pruning of cerebral blood vessels by degrading laminin and claudin-5. Angiogenesis 18(3): 255-264.
• 1609 Brand, F. J., 3rd, et al. (2015). RIG-I contributes to the innate immune response after cerebral ischemia. J Inflamm (Lond) 12(1): 52.
• 1610 Cai, L., et al. (2015). Weight loss: indication of brain damage and effect of combined normobaric oxygen and ethanol therapy after stroke. Neurol Res 37(5): 441-446.
• 1611 Carreras, A., et al. (2015). Resveratrol attenuates intermittent hypoxia-induced macrophage migration to visceral white adipose tissue and insulin resistance in male mice. Endocrinology 156(2): 437-443.
• 1612 Casalino-Matsuda, S. M., et al. (2015). Hypercapnia Inhibits Autophagy and Bacterial Killing in Human Macrophages by Increasing Expression of Bcl-2 and Bcl-xL. J Immunol 194(11): 5388-5396.
• 1613 Charrin, E., et al. (2015). Oxidative stress is decreased in physically active sickle cell SAD mice. British journal of haematology 168(5): 747-756
• 1614Chen, T., et al. (2015). Loss of miR-17~ 92 in Smooth Muscle Cells Attenuates Experimental Pulmonary Hypertension via Induction of PDLIM5. American journal of respiratory and critical care medicine(ja)
• 1615 Chen, W. L., et al. (2015). Cycling hypoxia induces chemoresistance through the activation of reactive oxygen species-mediated B-cell lymphoma extra-long pathway in glioblastoma multiforme. J Transl Med 13(1): 389.
• 1616 Chen, W., et al. (2015). TRPM7 inhibitor carvacrol protects brain from neonatal hypoxic-ischemic injury. Mol Brain 8(1): 11.
• 1617 Chen, Y. C., et al. (2015). Co-upregulation of Toll-like receptors 2 and 6 on peripheral blood cells in patients with obstructive sleep apnea. Sleep Breath 19(3): 873-882.
• 1618 Cherif, M., et al. (2015). Gab1 Is Modulated by Chronic Hypoxia in Children with Cyanotic Congenital Heart Defect and Its Overexpression Reduces Apoptosis in Rat Neonatal Cardiomyocytes. BioMed Research International 2015
• 1619 Chichger, H., et al. (2015). PKC δ and βII Regulate Angiotensin II Mediated Fibrosis through p38: A Mechanism of RV Fibrosis in Pulmonary Hypertension. American Journal of Physiology-Lung Cellular and Molecular Physiology: ajplung. 00184.02014
• 1620 Chiu, C. Z., et al. (2015). Molecular regulation of the expression of leptin by hypoxia in human coronary artery smooth muscle cells. J Biomed Sci 22(1): 5.
• 1621Choi, J. H., et al. (2015). Hypoxia Inducible Factor-1α Regulates the Migration of Bone Marrow Mesenchymal Stem Cells via Integrin α4. Stem Cells International
• 1622Choi, J. H., et al. (2015). Microenvironmental Interaction Between Hypoxia and Endothelial Cells Controls the Migration Ability of Placenta‐Derived Mesenchymal Stem Cells via α4 Integrin and Rho Signaling. Journal of cellular biochemistry
• 1623 Chow, A. K., et al. (2015). A preclinical study on the combination therapy of everolimus and transarterial chemoembolization in hepatocellular carcinoma. Am J Cancer Res 5(8): 2376-2386.
• 1624 Chu, A., et al. (2015). Cardiovascular dysfunction in adult mice following postnatal intermittent hypoxia. Pediatr Res 77(3): 425-433.
• 1625 Cikla, U., et al. (2015). Suppression of microglia activation after hypoxia–ischemia results in age-dependent improvements in neurologic injury. Journal of Neuroimmunology
• 1626 Cox, J., Ruan, et al. (2015). Aspirin-Triggered Resolvin D1 Treatment Enhances Resolution of Hyperoxic Acute Lung Injury. American Journal of Respiratory Cell and Molecular Biology(ja)
• 1627 Cunningham, K. F., et al. (2015). Estrogen-Related Receptor α (ERRα) Is Required for Adaptive Increases in PGC-1 Isoform Expression During Electrically Stimulated Contraction of Adult Cardiomyocytes in Sustained Hypoxic Conditions. International Journal of Cardiology
• 1628 Dada, L. A., et al. (2015). High CO2 Leads to Na,K-ATPase Endocytosis via c-Jun Amino-Terminal Kinase-Induced LMO7b Phosphorylation. Mol Cell Biol 35(23): 3962-3973.
• 1629 Das, K. C. (2015). Thioredoxin-deficient mice, a novel phenotype sensitive to ambient air and hypersensitive to hyperoxia-induced lung injury. Am J Physiol Lung Cell Mol Physiol 308(5): L429-442.
• 1630 Datta, A., et al. (2015). Mouse lung development and NOX1 induction during hyperoxia are developmentally regulated and mitochondrial ROS dependent. Am J Physiol Lung Cell Mol Physiol 309(4): L369-377.
• 1631 de Raaf, M. A., et al. (2015). Serotonin transporter is not required for the development of severe pulmonary hypertension in the Sugen hypoxia rat model. Am J Physiol Lung Cell Mol Physiol 309(10): L1164-1173.
• 1632 Deng, Y., et al. (2015). Efficacy of atorvastatin on hippocampal neuronal damage caused by chronic intermittent hypoxia: Involving TLR4 and its downstream signaling pathway. Respir Physiol Neurobiol 218: 57-63.
• 1633 Deng, Y., et al. (2015). P2X7 Receptor Antagonism Attenuates the Intermittent Hypoxia-induced Spatial Deficits in a Murine Model of Sleep Apnea Via Inhibiting Neuroinflammation and Oxidative Stress. Chin Med J (Engl) 128(16): 2168-2175.
• 1634 Dergacheva, O. (2015). Chronic intermittent hypoxia alters neurotransmission from lateral paragigantocellular nucleus to parasympathetic cardiac neurons in the brain stem. J Neurophysiol 113(1): 380-389.
• 1635 Diogo, L. N., et al. (2015). Efficacy of carvedilol in reversing hypertension induced by chronic intermittent hypoxia in rats. Eur J Pharmacol 765: 58-67.
• 1636 Do, J. Y., et al. (2015). Retinal hypoxia induces vascular endothelial growth factor through induction of estrogen-related receptor γ. Biochemical and biophysical research communications 460(2): 457-463
• 1637 Dokun, A. O., et al. (2015). ADAM12: a genetic modifier of preclinical peripheral arterial disease. Am J Physiol Heart Circ Physiol 309(5): H790-803.
• 1638 Domigan, C. K., et al. (2015). Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy. Journal of cell science: jcs. 163774
• 1639 Dominguez, E., et al. (2015). Experimental Branch Retinal Vein Occlusion Induces Upstream Pericyte Loss and Vascular Destabilization. PLOS ONE 10(7): e0132644.
• 1640 Duchez, P., et al. (2015). Interleukin-6 enhances the activity of in vivo long-term reconstituting hematopoietic stem cells in “hypoxic-like” expansion cultures ex vivo. Transfusion 55(11): 2684-2691.
• 1641Dyugovskaya, L., et al. (2015). Intermittent Hypoxia Affects the Spontaneous Differentiation In Vitro of Human Neutrophils into Long-Lived Giant Phagocytes. Oxidative Medicine and Cellular Longevity 2016
• 1642 Edgar, K. S., et al. (2015). Hyperoxia depletes (6R)-5,6,7,8-tetrahydrobiopterin levels in the neonatal retina: implications for nitric oxide synthase function in retinopathy. Am J Pathol 185(6): 1769-1782.
• 1643 El Refaey, M., et al. (2015). Oxidation of the aromatic amino acids tryptophan and tyrosine disrupts their anabolic effects on bone marrow mesenchymal stem cells. Molecular and cellular endocrinology
• 1644 Fan, L., et al. (2015). Transplantation of hypoxia preconditioned bone marrow mesenchymal stem cells enhances angiogenesis and osteogenesis in rabbit femoral head osteonecrosis. Bone 81: 544-553.
• 1645 Fan, Z., et al. (2015). YM155, a selective survivin inhibitor, reverses chronic hypoxic pulmonary hypertension in rats via upregulating voltage-gated potassium channels. Clin Exp Hypertens 37(5): 381-387.
• 1646Fang, L., et al. (2015). Regulation of Fibroblast Growth Factor 2 Expression in Oxygen-Induced Retinopathy. Investigative Ophthalmology & Visual Science 56(1): 207-215
• 1647 Fei, F., et al. (2015). Upregulation of Homer1a Promoted Retinal Ganglion Cell Survival After Retinal Ischemia and Reperfusion via Interacting with Erk Pathway. Cell Mol Neurobiol 35(7): 1039-1048.
• 1648 Fei, P., et al. (2015). Thrombospondin-2 Expression During Retinal Vascular Development and Neovascularization. J Ocul Pharmacol Ther 31(7): 429-444.
• 1649 Fischer, C., et al. (2015). Panobinostat reduces hypoxia-induced cisplatin resistance of non-small cell lung carcinoma cells via HIF-1alpha destabilization. Mol Cancer 14(1): 4.
• 1650 Foldager, C. B., et al. (2015). Collagen Type IV and Laminin Expressions during Cartilage Repair and in Late Clinically Failed Repair Tissues from Human Subjects. Cartilage: 1947603515604022
• 1651 Fröhlich, J. D., et al. (2015). Oxygen and glucose dependent viability of HLA-G positive and negative trophoblasts using ACH-3P cells as first trimester trophoblast-derived cell model. Journal of Reproductive Health and Medicine 1(1): 4-9.
• 1652 Fu, Z., et al. (2015). Deficiency of aldose reductase attenuates inner retinal neuronal changes in a mouse model of retinopathy of prematurity. Graefes Arch Clin Exp Ophthalmol 253(9): 1503-1513.
• 1653 Galam, L., et al. (2015). 4-hydroxynonenal regulates mitochondrial function in human small airway epithelial cells. Oncotarget 6(39): 41508-41521.
• 1654 Galam, L., et al. (2015). Adenovirus-mediated transfer of the SOCS-1 gene to mouse lung confers protection against hyperoxic acute lung injury. Free Radic Biol Med 84: 196-205.
• 1655 Geng, X., et al. (2015). Ethanol and normobaric oxygen: novel approach in modulating pyruvate dehydrogenase complex after severe transient and permanent ischemic stroke. Stroke 46(2): 492-499.
• 1656 Geng, X., et al. (2015). Reduced cerebral monocarboxylate transporters and lactate levels by ethanol and normobaric oxygen therapy in severe transient and permanent ischemic stroke. Brain Res 1603: 65-75.
• 1657 Gerace, E., et al. (2015). Interplay between histone acetylation/deacetylation and poly (ADP-ribosyl) ation in the development of ischemic tolerance in vitro. Neuropharmacology
• 1658 Gold, B., et al. (2015). A multi-stress model for high throughput screening against non-replicating Mycobacterium tuberculosis. Methods Mol Biol 1285: 293-315.
• 1659 Gopal, P., et al. (2015). Effect of chronic hypoxia on RAGE and its soluble forms in lungs and plasma of mice. Biochim Biophys Acta 1852(5): 992-1000.
• 1660 Goss, K. N., et al. (2015). Neonatal hyperoxic lung injury favorably alters adult right ventricular remodeling response to chronic hypoxia exposure. Am J Physiol Lung Cell Mol Physiol 308(8): L797-806.
• 1661 Granton, J., et al. (2015). Endothelial NO-Synthase Gene-Enhanced Progenitor Cell Therapy for Pulmonary Arterial Hypertension: The PHACeT Trial. Circ Res 117(7): 645-654.
• 1662 Green, D. E., et al. (2015). PPARγ Ligands Attenuate Hypoxia-Induced Proliferation in Human Pulmonary Artery Smooth Muscle Cells through Modulation of MicroRNA-21. PLOS ONE 10(7): e0133391.
• 1663 Guo, X., et al. (2015). Alterations in left ventricular function during intermittent hypoxia: Possible involvement of O-GlcNAc protein and MAPK signaling. Int J Mol Med 36(1): 150-158.
• 1664 Gupta, A., et al. (2015). SOD2 Activity Is not Impacted by Hyperoxia in Murine Neonatal Pulmonary Artery Smooth Muscle Cells and Mice. International journal of molecular sciences 16(3): 6373-6390
• 1665 Haga, C. L., et al. (2015). Small Molecule Inhibition of miR-544 Biogenesis Disrupts Adaptive Responses to Hypoxia by Modulating ATM-mTOR Signaling. ACS Chem Biol 10(10): 2267-2276.
• 1666 Hamalainen, R. H., et al. (2015). mtDNA Mutagenesis Disrupts Pluripotent Stem Cell Function by Altering Redox Signaling. Cell Rep 11(10): 1614-1624.
• 1667 Hao, K., et al. (2015). Inactivation of corticotropin-releasing hormone-induced insulinotropic role by high-altitude hypoxia. Diabetes 64(3): 785-795.
• 1668 Hartman, W., et al. (2015). Role of Hypoxia-Induced Brain Derived Neurotrophic Factor in Human Pulmonary Artery Smooth Muscle. PLOS ONE 10(7): e0129489.
• 1669 He, J., et al. (2015). Hypoxic adipose mesenchymal stem cells derived conditioned medium protects myocardial infarct in rat. Eur Rev Med Pharmacol Sci 19(22): 4397-4406.
• 1670 Helenius, I. T., et al. (2015). Identification of Drosophila Zfh2 as a Mediator of Hypercapnic Immune Regulation by a Genome-Wide RNA Interference Screen. The Journal of Immunology: 1501708
• 1671 Hoffmann, E. K., et al. (2015). Role of volume-regulated and calcium-activated anion channels in cell volume homeostasis, cancer and drug resistance. Channels (Austin) 9(6): 380-396.
• 1672 Hopper, N., et al. (2015). Peripheral blood derived mononuclear cells enhance the migration and chondrogenic differentiation of multipotent mesenchymal stromal cells. Stem Cells Int 2015: 323454.
• 1673 Hu, X., et al. (2015). Safety and efficacy of intracoronary hypoxia-preconditioned bone marrow mononuclear cell administration for acute myocardial infarction patients: The CHINA-AMI randomized controlled trial. Int J Cardiol 184: 446-451.
• 1674 Huan, J., et al. (2015). Coordinate regulation of residual bone marrow function by paracrine trafficking of AML exosomes. Leukemia 29(12): 2285-2295.
• 1675 Iizuka, N., et al. (2015). Retinal region-dependent susceptibility of capillaries to high-concentration oxygen exposure and vascular endothelial growth factor receptor inhibition in neonatal mice. J Pharmacol Sci 129(2): 107-118.
• 1676 Jaitovich, A., et al. (2015). High CO2 levels cause skeletal muscle atrophy via AMP-activated kinase (AMPK), FoxO3a protein, and muscle-specific Ring finger protein 1 (MuRF1). J Biol Chem 290(14): 9183-9194.
• 1677 Jang, K. J., et al. (2015). Mitochondrial function provides instructive signals for activation-induced B-cell fates. Nat Commun 6: 6750.
• 1678 Kaiser, A. D., et al. (2015). Towards a commercial process for the manufacture of genetically modified T cells for therapy. Cancer Gene Ther 22(2): 72-78.
• 1679Kang, B.-Y., et al. (2015). PPARγ Activation Reduces Hypoxia-induced Endothelin-1 Expression through Upregulation of miR-98. American Journal of Respiratory Cell and Molecular Biology(ja)
• 1680 Kim, B. H., et al. (2015). Imidazole-based alkaloid derivative LCB54-0009 suppresses ocular angiogenesis and lymphangiogenesis in models of experimental retinopathy and corneal neovascularization. Br J Pharmacol 172(15): 3875-3889.
• 1681 Kim, B. S., et al. (2015). Cyclin-dependent kinase five mediates activation of lung xanthine oxidoreductase in response to hypoxia. PLOS ONE 10(4): e0124189.
• 1682Kim, I. and J. Carroll (2015). Effect of Chronic Hypoxia on the Carotid Body Glomus Cell Mitochondrial Response to Acute Hypoxia. The FASEB Journal 29(1 Supplement): LB691
• 1683 Kim, K. K., et al. (2015). Tetrathiomolybdate inhibits mitochondrial complex IV and mediates degradation of hypoxia-inducible factor-1α in cancer cells. Scientific Reports 5
• 1684 Koh, H. S., et al. (2015). The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia. Nat Commun 6: 6340.
• 1685 Kolb, T. M., et al. (2015). Right ventricular angiogenesis is an early adaptive response to chronic hypoxia‐induced pulmonary hypertension. Microcirculation
• 1686 Krause, B. J., et al. (2015). Arginase-2 is cooperatively up-regulated by nitric oxide and histone deacetylase inhibition in human umbilical artery endothelial cells. Biochemical pharmacology
• 1687 Kurlak, L. O., et al. (2015). Human placental renin‐angiotensin system in normotensive and pre‐eclamptic pregnancies at high altitude and after acute hypoxia‐reoxygenation insult. The Journal of physiology
• 1688 Lages, Y. M., et al. (2015). Low oxygen alters mitochondrial function and response to oxidative stress in human neural progenitor cells. PeerJ 3: e1486.
• 1689 Laval, M., et al. (2015). Increased gastrin gene expression provides a physiological advantage to mice under hypoxic conditions. Am J Physiol Gastrointest Liver Physiol 308(2): G76-84.
• 1690Le Moan, N., et al. (2015). Hypoxia Inducible Factor-1α in Astrocytes and/or Myeloid Cells Is Not Required for the Development of Autoimmune Demyelinating Disease. eneuro 2(2): ENEURO. 0050-0014.2015
• 1691 Lee, H. S. and D. G. Lee (2015). rIL-10 enhances IL-10 signalling proteins in foetal alveolar type II cells exposed to hyperoxia. J Cell Mol Med 19(7): 1538-1547.
• 1692 Lewis, P., et al. (2015). Chronic sustained hypoxia-induced redox remodeling causes contractile dysfunction in mouse sternohyoid muscle. Front Physiol 6: 122.
• 1693 Lewis, P., et al. (2015). Redox Remodelling is Pivotal in Murine Diaphragm Muscle Adaptation to Chronic Sustained Hypoxia. American Journal of Respiratory Cell and Molecular Biology(ja)
• 1694 Li, K. C., et al. (2015). Preclinical Safety Evaluation of ASCs Engineered by FLPo/Frt-Based Hybrid Baculovirus: In Vitro and Large Animal Studies. Tissue Eng Part A 21(9-10): 1471-1482.
• 1695 Li, L., et al. (2015). Regulatory role of CARD3 in left ventricular remodelling and dysfunction after myocardial infarction. Basic Res Cardiol 110(6): 56.
• 1696 Li, M., et al. (2015). Protection of Diltiazem on Vascular Endothelial Cells against Angiotensin II and Hypoxia. Clinical and Experimental Pharmacology and Physiology
• 1697 Li, T., et al. (2015). Influence of Nano-HA Coated Bone Collagen to Acrylic (Polymethylmethacrylate) Bone Cement on Mechanical Properties and Bioactivity. PLOS ONE 10(6): e0129018.
• 1698 Liao, J., et al. (2015). The NLRP3 inflammasome is critically involved in the development of bronchopulmonary dysplasia. Nature communications 6
• 1699Lim, J., et al. (2015). Functionalized Biomaterials-Oxygen Releasing Scaffolds. J Biotechnol Biomater 5(182): 2
• 1700 Liu, B., et al. (2015). Augmented Wnt‐Signaling as a Therapeutic Tool to Prevent Ischemia and Reperfusion Injury in Liver: Preclinical Studies in a Mouse Model. Liver Transplantation
• 1701 Liu, F. J., et al. (2015). MiR-335 regulates Hif-1α to reduce cell death in both mouse cell line and rat ischemic models. PLOS ONE 10(6): e0128432
• 1702 Liu, T., et al. (2015). Hypoxia-induced MTA1 promotes MC3T3 osteoblast growth but suppresses MC3T3 osteoblast differentiation. Eur J Med Res 20(1): 10.
• 1703 Liu, X., et al. (2015). Vinexin-beta exacerbates cardiac dysfunction post-myocardial infarction via mediating apoptotic and inflammatory responses. Clin Sci (Lond) 128(12): 923-936.
• 1704 Liu, Y., et al. (2015). Hyperoxia-induced immature brain injury through the TLR4 signaling pathway in newborn mice. Brain research 1610: 51-60
• 1705 Llorente, I. L., et al. (2015). Glutamate receptor and transporter modifications in rat organotypic hippocampal slice cultures exposed to oxygen-glucose deprivation: the contribution of cyclooxygenase-2. Neuroscience 292: 118-128.
• 1706 Lottes, R. G., et al. (2015). Lactate as substrate for mitochondrial respiration in alveolar epithelial type II cells. American Journal of Physiology-Lung Cellular and Molecular Physiology 308(9): L953-L961
• 1707 Lu, C., et al. (2015). Attenuation of cardiac dysfunction and remodeling of myocardial infarction by microRNA-130a are mediated by suppression of PTEN and activation of PI3K dependent signaling. J Mol Cell Cardiol 89(Pt A): 87-97.
• 1708 Lu, J., et al. (2015). Cell orientation gradients on an inverse opal substrate. ACS Appl Mater Interfaces 7(19): 10091-10095.
• 1709 Lu, Q., et al. (2015). Autophagy in neonatal hypoxia ischemic brain is associated with oxidative stress. Redox Biology
• 1710 Lu, Q., et al. (2015). Nitric oxide induces hypoxia ischemic injury in the neonatal brain via the disruption of neuronal iron metabolism. Redox Biol 6: 112-121.
• 1711 Luangphakdy, V., et al. (2015). Evaluation of rhBMP-2/collagen/TCP-HA bone graft with and without bone marrow cells in the canine femoral multi defect model. Eur Cell Mater 29: 57-68; discussion 68-59.
• 1712 Madsen, J. S., et al. (2015). Facultative control of matrix production optimizes competitive fitness in Pseudomonas aeruginosa PA14 biofilm models. Appl Environ Microbiol 81(24): 8414-8426.
• 1713 Manchenkov, T., et al. (2015). Novel Genes Critical for Hypoxic Preconditioning in Zebrafish Are Regulators of Insulin and Glucose Metabolism. G3 (Bethesda) 5(6): 1107-1116.
• 1714 Marathe, C. S., et al. (2015). Islet cell transplantation in Australia: screening, remote transplantation, and incretin hormone secretion in insulin independent patients. Horm Metab Res 47(1): 16-23.
• 1715 Markway, B. D., et al. (2015). Hypoxia‐inducible factor 3‐alpha expression is associated with the stable chondrocyte phenotype. Journal of Orthopaedic Research
• 1716 Maurer, E., et al. (2015). Susceptibility profiles of amphotericin B and posaconazole against clinically relevant mucorales species under hypoxic conditions. Antimicrob Agents Chemother 59(2): 1344-1346.
• 1717 McDonald, F. B., et al. (2015). Early life exposure to chronic intermittent hypoxia causes upper airway dilator muscle weakness which persists into young adulthood. Experimental Physiology
• 1718 Mistry, R. K., et al. (2015). Transcriptional Regulation of Cystathionine-γ-lyase in Endothelial cells by NADPH oxidase 4-dependent Signaling. Journal of Biological Chemistry: jbc. M115. 685578
• 1719 Miyazaki, T., et al. (2015). Calpastatin counteracts pathological angiogenesis by inhibiting suppressor of cytokine signaling 3 degradation in vascular endothelial cells. Circ Res 116(7): 1170-1181.
• 1720Mizuuchi, M., et al. (2015). Placental endoplasmic reticulum stress negatively regulates transcription of placental growth factor via ATF4 and ATF6β: implications for the pathophysiology of human pregnancy complications. The Journal of pathology
• 1721 Mou, J., et al. (2015). Ultrasmall Cu2-x S Nanodots for Highly Efficient Photoacoustic Imaging-Guided Photothermal Therapy. Small 11(19): 2275-2283.
• 1722 Mouraret, N., et al. (2015). Role for telomerase in pulmonary hypertension. Circulation 131(8): 742-755.
• 1723 Niu, J., et al. (2015). Association between endothelin-1/endothelin receptor A and inflammation in mouse kidneys following acute ischemia/reperfusion. Molecular medicine reports 11(5): 3981-3987
• 1724 Nowak, G. and D. Bakajsova (2015). Protein kinase C-alpha interaction with F0F1-ATPase promotes F0F1-ATPase activity and reduces energy deficits in injured renal cells. J Biol Chem 290(11): 7054-7066.
• 1725 Oku, H., et al. (2015). Nitric Oxide Increases the Expression of Aquaporin-4 Protein in Rat Optic Nerve Astrocytes through the Cyclic Guanosine Monophosphate/Protein Kinase G Pathway. Ophthalmic research 54(4): 212-221
• 1726 Orłowska, J., et al. (2015). The use of biodegradable polymers in design of cellular scaffolds. Postepy Hig Med Dosw (online) 69: 294-301
• 1727 Påhlman, L. I., et al. (2015). Hypoxia down-regulates expression of secretory leukocyte protease inhibitor in bronchial epithelial cells via TGF-β1. BMC pulmonary medicine 15(1): 19.
• 1728 Parmar, J. and N. M. Jones (2015). Hypoxic preconditioning can reduce injury-induced inflammatory processes in the neonatal rat brain. International Journal of Developmental Neuroscience
• 1729 Peiris, H. N., et al. (2015). Expression of Myostatin in Intrauterine Growth Restriction and Preeclampsia Complicated Pregnancies and Alterations to Cytokine Production by First-Trimester Placental Explants Following Myostatin Treatment. Reprod Sci 22(10): 1202-1211.
• 1730 Perche, F., et al. (2015). Hypoxia-Responsive Copolymer for siRNA Delivery. RNA Imaging: Methods and Protocols: 139-162
• 1731 Perez-Sepulveda, A., et al. (2015). Placental Aromatase Is Deficient in Placental Ischemia and Preeclampsia. PLOS ONE 10(10): e0139682.
• 1732 Perim, R. R., et al. (2015). Cardiovascular and respiratory outcome of preconditioned rats submitted to chronic intermittent hypoxia. Exp Physiol 100(9): 1008-1017.
• 1733 Pfleger, J., et al. (2015). Mitochondrial complex II is a source of the reserve respiratory capacity that is regulated by metabolic sensors and promotes cell survival. Cell death & disease 6(7): e1835
• 1734 Pham, H., et al. (2015). Impact of inhaled nitric oxide on white matter damage in growth-restricted neonatal rats. Pediatr Res 77(4): 563-569.
• 1735 Phan Duy, A., et al. (2015). Nitric Oxide Pathway and Proliferation of Neural Progenitors in the Neonatal Rat. Dev Neurosci 37(4-5): 417-427.
• 1736 Phinney, D. G., et al. (2015). Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs. Nat Commun 6: 8472.
• 1737 Pittenger, M. F., et al. (2015). MSCs: Scientific Support for Multiple Therapies. Stem Cells Int 2015: 280572.
• 1738 Poniewierska-Baran, A., et al. (2015). Human rhabdomyosarcoma cells express functional erythropoietin receptor: Potential therapeutic implications. Int J Oncol 47(5): 1989-1997.
• 1739 Prows, D. R., et al. (2015). Age and Sex of Mice Markedly Affect Survival Times Associated with Hyperoxic Acute Lung Injury. PLOS ONE 10(6): e0130936.
• 1740 Rafikova, O., et al. (2015). The sexual dimorphism associated with pulmonary hypertension corresponds to a fibrotic phenotype. Pulm Circ 5(1): 184-197.
• 1741 Rama, N., et al. (2015). Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization. Nature medicine
• 1742 Rao, X., et al. (2015). O-GlcNAcylation of G6PD promotes the pentose phosphate pathway and tumor growth. Nat Commun 6: 8468.
• 1743 Reddy, N. M., et al. (2015). PI3K-AKT Signaling via Nrf2 Protects against Hyperoxia-Induced Acute Lung Injury, but Promotes Inflammation Post-Injury Independent of Nrf2 in Mice. PLOS ONE 10(6): e0129676.
• 1744 Rice, G. E., et al. (2015). The Effect of Glucose on the Release and Bioactivity of Exosomes From First Trimester Trophoblast Cells. J Clin Endocrinol Metab 100(10): E1280-1288.
• 1745 Rivera, J. C., et al. (2015). BIBF1120 (Vargatef) Inhibits Preretinal Neovascularization and Enhances Normal Vascularization in a Model of Vasoproliferative RetinopathyBIBF1120 in a Model of Vasoproliferative Retinopathy. Investigative Ophthalmology & Visual Science 56(13): 7897-7907
• 1746 Romacho, T., et al. (2015). Nutritional ingredients modulate adipokine secretion and inflammation in human primary adipocytes. Nutrients 7(2): 865-886.
• 1747 Ryland, K. E., et al. (2015). Polycomb-dependent repression of the potassium channel-encoding gene KCNA5 promotes cancer cell survival under conditions of stress. Oncogene 34(35): 4591-4600.
• 1748 Sallon, C., et al. (2015). Automated High-Performance Analysis of Lung Morphometry. Am J Respir Cell Mol Biol 53(2): 149-158.
• 1749 Sart, S., et al. (2015). Intracellular labeling of mouse embryonic stem cell-derived neural progenitor aggregates with micron-sized particles of iron oxide. Cytotherapy 17(1): 98-111.
• 1750 Schallner, N., et al. (2015). Microglia regulate blood clearance in subarachnoid hemorrhage by heme oxygenase-1. J Clin Invest 125(7): 2609-2625.
• 1751 Scharf, A., et al. (2015). Superparamagnetic iron oxide nanoparticles as a means to track mesenchymal stem cells in a large animal model of tendon injury. Contrast Media Mol Imaging 10(5): 388-397.
• 1752 Scheuer, T., et al. (2015). Oligodendroglial maldevelopment in the cerebellum after postnatal hyperoxia and its prevention by minocycline. Glia 63(10): 1825-1839.
• 1753 Schiavo, A. A., et al. (2015). Endothelial properties of third-trimester amniotic fluid stem cells cultured in hypoxia. Stem Cell Res Ther 6(1): 209.
• 1754 Schlaepfer, I. R., et al. (2015). Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation. Oncotarget 6(26): 22836-22856.
• 1755 Schlosser, K., et al. (2015). Discordant regulation of microRNA between multiple experimental models and human pulmonary hypertension. CHEST Journal
• 1756 Schrobback, K., et al. (2015). The importance of connexin hemichannels during chondroprogenitor cell differentiation in hydrogel versus microtissue culture models. Tissue Eng Part A 21(11-12): 1785-1794.
• 1757 Shanab, A. Y., et al. (2015). Candesartan stimulates reparative angiogenesis in ischemic retinopathy model: role of hemeoxygenase-1 (HO-1). Angiogenesis 18(2): 137-150.
• 1758 Shapiro, J. P., et al. (2015). Mass spectrometry identification of potential mediators of progestin-only contraceptive-induced abnormal uterine bleeding in human endometrial stromal cells. Contraception 91(3): 253-260.
• 1759 Sharma, S., et al. (2015). APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophages. Nat Commun 6: 6881.
• 1760 Sheikh, A. Q., et al. (2015). Smooth muscle cell progenitors are primed to muscularize in pulmonary hypertension. Sci Transl Med 7(308): 308ra159.
• 1761 Shen, X., et al. (2015). Altered viral replication and cell responses by inserting microRNA recognition element into PB1 in pandemic influenza A virus (H1N1) 2009. Mediators Inflamm 2015: 976575.
• 1762Sherwood, J., et al. (2015). Chronic CO2 retention stimulates gastric acid secretion and induces gastric mucosal hyperplasia in rats. The FASEB Journal 29(1 Supplement): 849.848
• 1763 Shi, T., et al. (2015). α 1A-Adrenergic receptor prevents cardiac ischemic damage through PKC δ/GLUT1/4-mediated glucose uptake. Journal of Receptors and Signal Transduction: 1-10
• 1764 Shi, Y., et al. (2015). Temporal and spatial changes in VEGF, αA-and αB-crystallin expression in a mouse model of oxygen-induced retinopathy. Int J Clin Exp Med 8(3): 3349-3359
• 1765 Shimi, T., et al. (2015). Structural Organization of Nuclear Lamins A, C, B1 and B2 Revealed by Super-Resolution Microscopy. Molecular biology of the cell: mbc. E15-07-0461
• 1766 Shin, D. H., et al. (2015). Regulation of MMP-1 expression in response to hypoxia is dependent on the intracellular redox status of metastatic bladder cancer cells. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852(12): 2593-2602
• 1767 Sidaly, R., et al. (2015). Hypoxia increases the expression of enamel genes and cytokines in an ameloblast-derived cell line. Eur J Oral Sci 123(5): 335-340.
• 1768 Sifringer, M., et al. (2015). Neuroprotective effect of dexmedetomidine on hyperoxia-induced toxicity in the neonatal rat brain. Oxid Med Cell Longev 2015: 530371.
• 1769 Sitaras, N., et al. (2015). Retinal neurons curb inflammation and enhance revascularization in ischemic retinopathies via proteinase-activated receptor-2. Am J Pathol 185(2): 581-595.
• 1770 Siwetz, M., et al. (2015). Placental Fractalkine Is Up-Regulated in Severe Early-Onset Preeclampsia. The American Journal of Pathology
• 1771Slot, I. G., et al. (2015). Alterations in Skeletal Muscle Oxidative Phenotype in Mice Exposed to Three Weeks of Normobaric Hypoxia. Journal of Cellular Physiology
• 1772Smith, K. A., et al. (2015). Notch Activation of Ca2+ Signaling Mediates Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension. American Journal of Respiratory Cell and Molecular Biology(ja)
• 1773 Soetikno, B. T., et al. (2015). Inner retinal oxygen metabolism in the 50/10 oxygen-induced retinopathy model. Sci Rep 5: 16752.
• 1774 Soliman, S., et al. (2015). Sequential Therapy with Minocycline and Candesartan Improves Long-Term Recovery After Experimental Stroke. Transl Stroke Res 6(4): 309-322.
• 1775 Song, J., et al. (2015). HIF-mediated increased ROS from reduced mitophagy and decreased catalase causes neocytolysis. J Mol Med (Berl) 93(8): 857-866.
• 1776 Souza, G. M., et al. (2015). Cardiovascular and respiratory responses to chronic intermittent hypoxia in adult female rats. Exp Physiol 100(3): 249-258.
• 1777 Staal, J. A., et al. (2015). Proteomic profiling of high risk medulloblastoma reveals functional biology. Oncotarget 6(16): 14584-14595.
• 1778 Suleiman, M. S., et al. (2015). Cardioprotection during Adult and Pediatric Open Heart Surgery. Biomed Res Int 2015: 712721.
• 1779 Sullivan, K. E., et al. (2015). An in vitro model for the assessment of stem cell fate following implantation within the infarct microenvironment identifies ISL-1 expression as the strongest predictor of c-Kit+ cardiac progenitor cells’ therapeutic potential. Journal of molecular and cellular cardiology 88: 91-100.
• 1780 Sun, H. S., et al. (2015). Neuronal K(ATP) channels mediate hypoxic preconditioning and reduce subsequent neonatal hypoxic-ischemic brain injury. Exp Neurol 263: 161-171.
• 1781 Sun, J., et al. (2015). Intranasal delivery of hypoxia-preconditioned bone marrow-derived mesenchymal stem cells enhanced regenerative effects after intracerebral hemorrhagic stroke in mice. Exp Neurol 272: 78-87.
• 1782 Sun, P., et al. (2015). Mindin deficiency protects the liver against ischemia/reperfusion injury. J Hepatol 63(5): 1198-1211.
• 1783 Sun, Y., et al. (2015). The biosafety of lanthanide upconversion nanomaterials. Chem Soc Rev 44(6): 1509-1525.
• 1784 Ta, N. L. and T. N. Seyfried (2015). Influence of Serum and Hypoxia on Incorporation of [14C]-d-Glucose or [14C]-l-Glutamine into Lipids and Lactate in Murine Glioblastoma Cells. Lipids 50(12): 1167-1184
• 1785 Tafreshi, N. K., et al. (2015). Evaluation of CAIX and CAXII Expression in Breast Cancer at Varied O2 Levels: CAIX is the Superior Surrogate Imaging Biomarker of Tumor Hypoxia. Molecular Imaging and Biology: 1-13
• 1786 Tang, X., et al. (2015). hCLOCK causes Rho-kinase-mediated endothelial dysfunction and NF-κB-mediated inflammatory responses. Oxidative Medicine and Cellular Longevity
• 1787 Teo, J. D., et al. (2015). Hypoxic postconditioning reduces microglial activation, astrocyte and caspase activity, and inflammatory markers after hypoxia-ischemia in the neonatal rat brain. Pediatr Res 77(6): 757-764.
• 1788 Thurmond, P., et al. (2015). Structural modifications of the prostate in hypoxia, oxidative stress, and chronic ischemia. Korean J Urol 56(3): 187-196.
• 1789 Tibboel, J., et al. (2015). Hypoxia-Inducible Factor-1 Stimulates Postnatal Lung Development but Does Not Prevent O2-Induced Alveolar Injury. American Journal of Respiratory Cell and Molecular Biology 52(4): 448-458
• 1790 Tojo, Y., et al. (2015). Hypoxia Signaling Cascade for Erythropoietin Production in Hepatocytes. Mol Cell Biol 35(15): 2658-2672.
• 1791 Townsend, D. (2015). Diastolic dysfunction precedes hypoxia-induced mortality in dystrophic mice. Physiol Rep 3(8): e12513.
• 1792 Tsai, A. C., et al. (2015). Compaction, fusion, and functional activation of three-dimensional human mesenchymal stem cell aggregate. Tissue Eng Part A 21(9-10): 1705-1719.
• 1793 Tsai, C.-H., et al. (2015). NcoA2-dependent inhibition of HIF-1α activation is regulated via AhR. Toxicological Sciences: kfv199
• 1794 Tsai, M. J., et al. (2015). Acidic FGF promotes neurite outgrowth of cortical neurons and improves neuroprotective effect in a cerebral ischemic rat model. Neuroscience 305: 238-247.
• 1795 Tse, A. C., et al. (2015). Hypoxia induces miR-210, leading to anti-apoptosis in ovarian follicular cells of marine medaka Oryzias melastigma. Aquat Toxicol 165: 189-196.
• 1796 Tu, C., et al. (2015). Proteomic profiling of the retinas in a neonatal rat model of oxygen-induced retinopathy with a reproducible ion-current-based MS1 approach. J Proteome Res 14(5): 2109-2120.
• 1797 Tucker, B., et al. (2015). Using patient specific iPSCs to interrogate the pathogenicity of a novel RPE65 cryptic splice site mutation and confirm eligibility for enrollment into a clinical gene augmentation trial. Translational research: the journal of laboratory and clinical medicine 166(6): 740
• 1798 Uddin, M. I., et al. (2015). Applications of azo-based probes for imaging retinal hypoxia. ACS Med Chem Lett 6(4): 445-449.
• 1799 Vasilevskaya, I. A., et al. (2015). Inhibition of JNK Sensitizes Hypoxic Colon Cancer Cells to DNA-Damaging Agents. Clin Cancer Res 21(18): 4143-4152.
• 1800 Verduzco, D., et al. (2015). Intermittent hypoxia selects for genotypes and phenotypes that increase survival, invasion, and therapy resistance. PLOS ONE 10(3)
• 1801 Vogel, J., et al. (2015). Nox4 supports proper capillary growth in exercise and retina neo-vascularization. J Physiol 593(9): 2145-2154.
• 1802 Wan, N., et al. (2015). Toll‐interacting protein contributes to mortality following myocardial infarction through promoting inflammation and apoptosis. British Journal of Pharmacology
• 1803 Wang, C.-Y., et al. (2015). PKC-dependent GAP43 phosphorylation regulates gephyrin aggregation at developing GABAergic synapses. Molecular and Cellular Biology: MCB. 01332-01314
• 1804 Wang, J., et al. (2015). Recommendation for modifying current cytotoxicity testing standards for biodegradable magnesium-based materials. Acta Biomater 21: 237-249.
• 1805 Wang, X., et al. (2015). Hypoxia precondition promotes adipose-derived mesenchymal stem cells based repair of diabetic erectile dysfunction via augmenting angiogenesis and neuroprotection. PLOS ONE 10(3): e0118951.
• 1806 Webb, T. E., et al. (2015). An internal ribosome entry site in the 5′ untranslated region of epidermal growth factor receptor allows hypoxic expression. Oncogenesis 4(1): e134.
• 1807 Wenger, R. H., et al. (2015). Frequently asked questions in hypoxia research. Hypoxia (Auckl) 3: 35-43.
• 1808 Whitmore, S. S., et al. (2015). Complement activation and choriocapillaris loss in early AMD: implications for pathophysiology and therapy. Prog Retin Eye Res 45: 1-29.
• 1809 Wiley, L. A., et al. (2015). Patient-specific induced pluripotent stem cells (iPSCs) for the study and treatment of retinal degenerative diseases. Prog Retin Eye Res 44: 15-35.
• 1810 Wiley, L. A., et al. (2015). Stem cells as tools for studying the genetics of inherited retinal degenerations. Cold Spring Harbor perspectives in medicine 5(5): a017160
• 1811 Wilkinson, L. J., et al. (2015). Renal developmental defects resulting from in utero hypoxia are associated with suppression of ureteric beta-catenin signaling. Kidney Int 87(5): 975-983.
• 1812 Williams, R., et al. (2015). Chronic intermittent hypoxia increases rat sternohyoid muscle NADPH oxidase expression with attendant modest oxidative stress. Front Physiol 6: 15.
• 1813 Witthaus, M. W., et al. (2015). Bladder oxidative stress in sleep apnea contributes to detrusor instability and nocturia. J Urol 193(5): 1692-1699.
• 1814 Won, S., et al. (2015). Recombinant tissue plasminogen activator promotes, and progesterone attenuates, microglia/macrophage M1 polarization and recruitment of microglia after MCAO stroke in rats. Brain Behav Immun 49: 267-279.
• 1815 Won, S., et al. (2015). Vitamin D prevents hypoxia/reoxygenation-induced blood-brain barrier disruption via vitamin D receptor-mediated NF-kB signaling pathways. PLOS ONE 10(3): e0122821.
• 1816 Wong, L. L., et al. (2015). Natriuretic peptide receptor 3 (NPR3) is regulated by microRNA-100. Journal of molecular and cellular cardiology 82: 13-21
• 1817 Woods, I. G. and F. B. Imam (2015). Transcriptome analysis of severe hypoxic stress during development in zebrafish. Genom Data 6: 83-88.
• 1818 Xie, S., et al. (2015). Melatonin protects against chronic intermittent hypoxia-induced cardiac hypertrophy by modulating autophagy through the 5′ adenosine monophosphate-activated protein kinase pathway. Biochemical and biophysical research communications
• 1819 Xing, L., et al. (2015). A Serotonin Circuit Acts as an Environmental Sensor to Mediate Midline Axon Crossing through EphrinB2. The Journal of Neuroscience 35(44): 14794-14808
• 1820 Xu, J., et al. (2015). NOTCH reprograms mitochondrial metabolism for proinflammatory macrophage activation. J Clin Invest 125(4): 1579-1590.
• 1821 Yamaguchi, J., et al. (2015). Inflammation and hypoxia linked to renal injury by CCAAT/enhancer-binding protein delta. Kidney Int 88(2): 262-275.
• 1822 Yan, L., et al. (2015). Single and Compound Knock-outs of MicroRNA (miRNA)-155 and Its Angiogenic Gene Target CCN1 in Mice Alter Vascular and Neovascular Growth in the Retina via Resident Microglia. J Biol Chem 290(38): 23264-23281.
• 1823 Yang, F., et al. (2015). Effects of Apelin on RAW264. 7 cells under both normal and hypoxic conditions. Peptides 69: 133-143
• 1824 Yang, Q., et al. (2015). IGF-1 signaling in neonatal hypoxia-induced pulmonary hypertension: Role of epigenetic regulation. Vascul Pharmacol 73: 20-31.
• 1825 Yang, W. J., et al. (2015). Semaphorin‐3C signals through Neuropilin‐1 and PlexinD1 receptors to inhibit pathological angiogenesis. EMBO molecular medicine: e201404922
• 1826 Yao, J., et al. (2015). Enhanced differentiation and delivery of mouse retinal progenitor cells using a micropatterned biodegradable thin-film polycaprolactone scaffold. Tissue Engineering Part A 21(7-8): 1247-1260.
• 1827 Yeh, T.-H., et al. (2015). Selective intracellular delivery of recombinant arginine deiminase (ADI) using pH-sensitive cell penetrating peptides to overcome ADI resistance in hypoxic breast cancer cells. Molecular pharmaceutics
• 1828 Yen, T.-L., et al. (2015). Andrographolide stimulates p38 MAPK-Nrf2-HO-1 signaling in primary cerebral endothelial cells for definite protection against ischemic stroke in rats. Translational Research
• 1829 Yilmaz, C., et al. (2015). Alveolar-capillary adaptation to chronic hypoxia in the fatty lung. Acta Physiol (Oxf) 213(4): 933-946.
• 1830 Yong, K. W., et al. (2015). Cryopreservation of Human Mesenchymal Stem Cells for Clinical Applications: Current Methods and Challenges. Biopreserv Biobank 13(4): 231-239.
• 1831 Yuan, X., et al. (2015). Chronic intermittent hypoxia-induced neuronal apoptosis in the hippocampus is attenuated by telmisartan through suppression of iNOS/NO and inhibition of lipid peroxidation and inflammatory responses. Brain research 1596: 48-57.
• 1832 Yuan, X., et al. (2015). Telmisartan attenuates myocardial apoptosis induced by chronic intermittent hypoxia in rats: modulation of nitric oxide metabolism and inflammatory mediators. Sleep Breath 19(2): 703-709.
• 1833 Zaitoun, I. S., et al. (2015). Endothelium Expression of Bcl-2 Is Essential for Normal and Pathological Ocular Vascularization. PLOS ONE 10(10): e0139994
• 1834 Zeng, Y., et al. (2015). Hypoxia inducible factor-1 mediates expression of miR-322: potential role in proliferation and migration of pulmonary arterial smooth muscle cells. Sci Rep 5: 12098.
• 1835 Zhang, H., et al. (2015). TIPE2 acts as a negative regulator linking NOD2 and inflammatory responses in myocardial ischemia/reperfusion injury. Journal of Molecular Medicine: 1-11
• 1836 Zhang, L., et al. (2015). Autophagy regulates hyperoxia-induced intracellular accumulation of surfactant protein C in alveolar type II cells. Mol Cell Biochem 408(1-2): 181-189.
• 1837 Zhang, L., et al. (2015). The role of placenta growth factor in the hyperoxia-induced acute lung injury in an animal model. Cell Biochem Funct 33(1): 44-49.
• 1838 Zhang, M., et al. (2015). Notch3/Akt signaling contributes to OSM-induced protection against cardiac ischemia/reperfusion injury. Apoptosis 20(9): 1150-1163.
• 1839Zhao, Y., et al. (2015). Three-dimensional Pt x Ni 1− x nanoclusters supported on multiwalled carbon nanotubes in enzyme-free glucose biofuel cells. Journal of Power Sources 296: 30-39
• 1840 Zheleznyak, A., et al. (2015). Preclinical Positron Emission Tomographic Imaging of Acute Hyperoxia Therapy of Chronic Hypoxia during Pregnancy. Mol Imaging 14: 366-372.
• 1841 Zhen, Y. Q., et al. (2015). 2,3-Oxidosqualene cyclase protects liver cells from the injury of intermittent hypoxia by regulating lipid metabolism. Sleep Breath 19(4): 1475-1481.
• 1842 Zhu, H., et al. (2015). Microencapsulated Pig Islet Xenotransplantation as an Alternative Treatment of Diabetes. Tissue Eng Part B Rev 21(5): 474-489.
• 1843 Abdelsaid, M. A., et al. (2014). Deletion of thioredoxin interacting protein (TXNIP) augments hyperoxia-induced vaso-obliteration in a mouse model of oxygen induced-retinopathy. PLOS ONE 9(10): e110388.
• 1844 Abdul, K. S. M., et al. (2014). Upregulation of cardioprotective SUR2A by sub-hypoxic drop in oxygen. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research
• 1845 Ahmad, A., et al. (2014). Benefits of pre-, pro- and Syn-biotics for lung angiogenesis in malnutritional rats exposed to intermittent hypoxia. Am J Transl Res 6(5): 459-470.
• 1846 Almado, C. E. L., et al. (2014). Intrinsic properties of rostral ventrolateral medulla presympathetic and bulbospinal respiratory neurons of juvenile rats are not affected by chronic intermittent hypoxia. Experimental Physiology 99(7): 937-950.
• 1847 Alphonse, R. S., et al. (2014). Existence, functional impairment, and lung repair potential of endothelial colony-forming cells in oxygen-induced arrested alveolar growth. Circulation 129(21): 2144-2157.
• 1848 Al-Qahtani, J. M., et al. (2014). Long-term moderate dose exogenous erythropoietin treatment protects from intermittent hypoxia-induced spatial learning deficits and hippocampal oxidative stress in young rats. Neurochem Res 39(1): 161-171.
• 1849 Amsellem, V., et al. (2014). CCR5 as a Treatment Target in Pulmonary Arterial Hypertension. Circulation 130(11): 880-891.
• 1850Anne, H.-H. T., et al. (2014). SIRT3 interactions with FOXO3 acetylation, phosphorylation and ubiquitinylation mediate endothelial cell responses to hypoxia. Biochemical Journal 464(1): 157-168
• 1851 Anyanwu, A. C., et al. (2014). Suppression of inflammatory cell trafficking and alveolar simplification by the heme oxygenase-1 product carbon monoxide. Am J Physiol Lung Cell Mol Physiol 306(8): L749-763.
• 1852 Baddoura, P., et al. (2014). Right Ventricular Angiogenesis Is An Early Adaptive Response To Chronic Hypoxia-Induced Pulmonary Hypertension. Am J Respir Crit Care Med 189: A2351
• 1853 Baranov, P. Y., et al. (2014). Low-oxygen culture conditions extend the multipotent properties of human retinal progenitor cells. Tissue Eng Part A 20(9-10): 1465-1475.
• 1854 Barbosa, M., et al. (2014). Integral-geometry characterization of photobiomodulation effects on retinal vessel morphology. Biomed Opt Express 5(7): 2317-2332.
• 1855 Bauer, E. M., et al. (2014). Recombinant human interferon alpha 2b prevents and reverses experimental pulmonary hypertension. PLOS ONE 9(5): e96720.
• 1856 Bertagnolli, M., et al. (2014). Transient Neonatal High Oxygen Exposure Leads to Early Adult Cardiac Dysfunction, Remodeling, and Activation of the Renin–Angiotensin System. Hypertension 63(1): 143-150.
• 1857 Blank, T. and W. Burggren (2014). Hypoxia-induced developmental plasticity of the gills and air-breathing organ of Trichopodus trichopterus. J Fish Biol 84(3): 808-826.
• 1858 Brodowski, L., et al. (2014). Vitamin D prevents endothelial progenitor cell dysfunction induced by sera from women with preeclampsia or conditioned media from hypoxic placenta. PLOS ONE 9(6): e98527.
• 1859 Buck, L. D., et al. (2014). Co-regulation of primary mouse hepatocyte viability and function by oxygen and matrix. Biotechnol Bioeng 111(5): 1018-1027.
• 1860 Burnight, E. R., et al. (2014). CEP290 gene transfer rescues Leber congenital amaurosis cellular phenotype. Gene Ther 21(7): 662-672.
• 1861 Campen, M. J., et al. (2014). Muscle RING finger-1 promotes a maladaptive phenotype in chronic hypoxia-induced right ventricular remodeling. PLOS ONE 9(5): e97084.
• 1862 Capozzi, M. E., et al. (2014). The role of cytochrome P450 epoxygenases in retinal angiogenesis. Invest Ophthalmol Vis Sci 55(7): 4253-4260.
• 1863 Chavez-Perez, V. A., et al. (2014). Hypoxia and hypoxia mimetic cooperate to counteract tumor cell resistance to glucose starvation preferentially in tumor cells with mutant p53. Biochem Biophys Res Commun 443(1): 120-125.
• 1864 Chen, L., et al. (2014). Conditioned medium from hypoxic bone marrow-derived mesenchymal stem cells enhances wound healing in mice. PLOS ONE 9(4): e96161.
• 1865 Chen, P., et al. (2014). Hypoxia preconditioned mesenchymal stem cells prevent cardiac fibroblast activation and collagen production via leptin. PLOS ONE 9(8): e103587.
• 1866 Chen, W., et al. (2014). CYP2J2 and EETs Protect against Oxidative Stress and Apoptosis in Vivo and in Vitro Following Lung Ischemia/Reperfusion. Cell Physiol Biochem 33(6): 1663-1680.
• 1867 Chen, Y., et al. (2014). Highly effective inhibition of lung cancer growth and metastasis by systemic delivery of siRNA via multimodal mesoporous silica-based nanocarrier. Biomaterials 35(38): 10058-10069.
• 1868 Chiu, C. Z., et al. (2014). Angiotensin II and the JNK pathway mediate urotensin II expression in response to hypoxia in rat cardiomyocytes. J Endocrinol 220(3): 233-246.
• 1869 Choi, B. H., et al. (2014). Highly purified mussel adhesive protein to secure biosafety for in vivo applications. Microb Cell Fact 13(1): 52.
• 1870 Collet, G., et al. (2014). Hypoxia-regulated overexpression of soluble VEGFR2 controls angiogenesis and inhibits tumor growth. Mol Cancer Ther 13(1): 165-178.
• 1871Cullberg, K. B., et al. (2014). Inhibitory effects of resveratrol on hypoxia-induced inflammation in 3T3-L1 adipocytes and macrophages. Journal of Functional Foods 7: 171-179
• 1872 Dai, T., et al. (2014). Dextran-based fluorescent nanoprobes for sentinel lymph node mapping. Biomaterials 35(28): 8227-8235.
• 1873 Darashchonak, N., et al. (2014). Activation of adenosine A 2B receptor impairs properties of trophoblast cells and involves mitogen-activated protein (MAP) kinase signaling. Placenta 35(9): 763-771.
• 1874 Darashchonak, N., et al. (2014). Adenosine A2B receptors induce proliferation, invasion and activation of cAMP response element binding protein (CREB) in trophoblast cells. BMC Pregnancy Childbirth 14(1): 2.
• 1875 Davies, J., et al. (2014). Adenosine promotes vascular barrier function in hyperoxic lung injury. Physiol Rep 2(9): e12155.
• 1876 de Raaf, M. A., et al. (2014). SuHx rat model: partly reversible pulmonary hypertension and progressive intima obstruction. Eur Respir J 44(1): 160-168.
• 1877 Decembrini, S., et al. (2014). Derivation of traceable and transplantable photoreceptors from mouse embryonic stem cells. Stem Cell Reports 2(6): 853-865.
• 1878 Dergacheva, O., et al. (2014). Chronic intermittent hypoxia and hypercapnia inhibit the hypothalamic paraventricular nucleus neurotransmission to parasympathetic cardiac neurons in the brain stem. Hypertension 64(3): 597-603.
• 1879Deschepper, M., et al. (2014). NUTRIENT AND O2 TENSION ARE CRUCIAL REGULATORS OF HUMAN MESENCHYMAL STEM CELLS (HMSCS) PARACRINE POTENTIALITIES. Bone & Joint Journal Orthopaedic Proceedings Supplement 96(SUPP 11): 117-117
• 1880 Dier, U., et al. (2014). Bioenergetic analysis of ovarian cancer cell lines: profiling of histological subtypes and identification of a mitochondria-defective cell line. PLOS ONE 9(5): e98479.
• 1881 Ding, W. X., et al. (2014). Adiponectin protects rat heart from left ventricular remodeling induced by chronic intermittent hypoxia via inhibition of TGF-beta/smad2/3 pathway. J Thorac Dis 6(9): 1278-1284.
• 1882 Dong, J., et al. (2014). Preparation, characterization, and in vitro cytotoxicity evaluation of a novel anti-tuberculosis reconstruction implant. PLOS ONE 9(4): e94937.
• 1883 dos Santos, P. R., et al. (2014). Modified in vivo lung perfusion allows for prolonged perfusion without acute lung injury. J Thorac Cardiovasc Surg 147(2): 774-781: discussion 781-772.
• 1884 Dunlop, K., et al. (2014). Therapeutic hypercapnia prevents inhaled nitric oxide-induced right-ventricular systolic dysfunction in juvenile rats. Free Radic Biol Med 69: 35-49.
• 1885 Duong-Quy, S., et al. (2014). Early inhaled nitric oxide at high dose enhances rat lung development after birth. Nitric Oxide 38: 8-16.
• 1886 Dyavanapalli, J., et al. (2014). Chronic intermittent hypoxia–hypercapnia blunts heart rate responses and alters neurotransmission to cardiac vagal neurons. The Journal of physiology 592(13): 2799-2811
• 1887 Endesfelder, S., et al. (2014). Caffeine protects neuronal cells against injury caused by hyperoxia in the immature brain. Free Radic Biol Med 67: 221-234.
• 1888 Enomoto, M., et al. (2014). Newborn rat response to single vs. combined cGMP-dependent pulmonary vasodilators. Am J Physiol Lung Cell Mol Physiol 306(2): L207-215.
• 1889 Entezari, M., et al. (2014). Inhibition of extracellular HMGB1 attenuates hyperoxia-induced inflammatory acute lung injury. Redox Biol 2: 314-322.
• 1890 Eurlings, I. M., et al. (2014). Cigarette smoke extract induces a phenotypic shift in epithelial cells; involvement of HIF1alpha in mesenchymal transition. PLOS ONE 9(10): e107757.
• 1891 Fancy, S. P., et al. (2014). Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer. Nat Neurosci 17(4): 506-512.
• 1892 Fawzi, A. A., et al. (2014). Sildenafil attenuates vaso-obliteration and neovascularization in a mouse model of retinopathy of prematurity. Invest Ophthalmol Vis Sci 55(3): 1493-1501.
• 1893 Fazzi, F., et al. (2014). TNFR1/phox interaction and TNFR1 mitochondrial translocation Thwart silica-induced pulmonary fibrosis. J Immunol 192(8): 3837-3846.
• 1894 Frazier, T. P., et al. (2014). Human adipose-derived stromal/stem cells induce functional CD4+CD25+FoxP3+CD127- regulatory T cells under low oxygen culture conditions. Stem Cells Dev 23(9): 968-977.
• 1895 Gantenbein, B., et al. (2014). Activation of intervertebral disc cells by co-culture with notochordal cells, conditioned medium and hypoxia. BMC Musculoskelet Disord 15(1): 422.
• 1896 Gaston, B., et al. (2014). Essential role of hemoglobin beta-93-cysteine in posthypoxia facilitation of breathing in conscious mice. J Appl Physiol (1985) 116(10): 1290-1299.
• 1897 Ghanian, Z., et al. (2014). Organ specific optical imaging of mitochondrial redox state in a rodent model of hereditary hemorrhagic telangiectasia-1. J Biophotonics 7(10): 799-809.
• 1898 Gong, X., et al. (2014). Trimetazidine protects umbilical cord mesenchymal stem cells against hypoxia and serum deprivation induced apoptosis by activation of Akt. Cell Physiol Biochem 34(6): 2245-2255.
• 1899 Gosal, K., et al. (2014). Rho-kinase Mediates Right Ventricular Systolic Dysfunction in Rats with Chronic Neonatal Pulmonary Hypertension. American Journal of Respiratory Cell and Molecular Biology(ja)
• 1900 Guan, X., et al. (2014). Enhancement of osteogenesis and biodegradation control by brushite coating on Mg-Nd-Zn-Zr alloy for mandibular bone repair. ACS Appl Mater Interfaces 6(23): 21525-21533.
• 1901 Guo, X., et al. (2014). PGC-1α Signaling Coordinates Susceptibility to Metabolic and Oxidative Injury in the Inner Retina. The American Journal of Pathology 184(4): 1017-1029.
• 1902 Gutsaeva, D. R., et al. (2014). Molecular mechanisms underlying synergistic adhesion of sickle red blood cells by hypoxia and low nitric oxide bioavailability. Blood 123(12): 1917-1926.
• 1903 Han, Q., et al. (2014). Cellular mechanisms in intermittent hypoxia-induced cardiac damage in vivo. J Physiol Biochem 70(1): 201-213.
• 1904 Han, Y., et al. (2014). Emetine enhances the tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of pancreatic cancer cells by downregulation of myeloid cell leukemia sequence-1 protein. Oncol Rep 31(1): 456-462.
• 1905Harada, T., et al. (2014). Decreased “ineffective erythropoiesis” preserves polycythemia in mice under long-term hypoxia. Clinical and experimental medicine: 1-10
• 1906 Hasnain, S. Z., et al. (2014). Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress. Nat Med 20(12): 1417-1426.
• 1907 Heylman, C. M., et al. (2014). Modeling and experimental methods to predict oxygen distribution in bone defects following cell transplantation. Med Biol Eng Comput 52(4): 321-330.
• 1908 Hoppe, G., et al. (2014). Inducing a Visceral Organ to Protect a Peripheral Capillary Bed: Stabilizing Hepatic HIF-1α Prevents Oxygen-Induced Retinopathy. The American Journal of Pathology 184(6): 1890-1899.
• 1909 Hou, P., et al. (2014). Intermediary Metabolite Precursor Dimethyl-2-Ketoglutarate Stabilizes Hypoxia-Inducible Factor-1α by Inhibiting Prolyl-4-Hydroxylase PHD2. PLOS ONE 9(11): e113865.
• 1910 Howell, K. R. and A. Pillai (2014). Effects of prenatal hypoxia on schizophrenia-related phenotypes in heterozygous reeler mice: A gene× environment interaction study. European Neuropsychopharmacology 24(8): 1324-1336.
• 1911 Hu, X., et al. (2014). Severe hypoxia exerts parallel and cell-specific regulation of gene expression and alternative splicing in human mesenchymal stem cells. BMC genomics 15(1): 303.
• 1912 Huang, T., et al. (2014). Hypoxia-inducible factor-1α upregulation in microglia following hypoxia protects against ischemia-induced cerebral infarction. NeuroReport 25(14): 1122-1128
• 1913 Huyard, F., et al. (2014). Remodeling of Aorta Extracellular Matrix as a Result of Transient High Oxygen Exposure in Newborn Rats: Implication for Arterial Rigidity and Hypertension Risk. PLOS ONE 9(4): e92287.
• 1914 Ibrahim, Y. F., et al. (2014). Mechanism of the susceptibility of remodeled pulmonary vessels to drug-induced cell killing. J Am Heart Assoc 3(1): e000520.
• 1915 Isakova, I. A., et al. (2014). Allo-reactivity of mesenchymal stem cells in rhesus macaques is dose and haplotype dependent and limits durable cell engraftment in vivo. PLOS ONE 9(1): e87238.
• 1916 Jagadapillai, R., et al. (2014). Ceftriaxone preserves glutamate transporters and prevents intermittent hypoxia-induced vulnerability to brain excitotoxic injury. PLOS ONE 9(7): e100230.
• 1917 Januszyk, M., et al. (2014). Diabetes Irreversibly Depletes Bone Marrow–Derived Mesenchymal Progenitor Cell Subpopulations. Diabetes 63(9): 3047-3056.
• 1918 Jeong, D., et al. (2014). Anti-inflammatory activities and mechanisms of Artemisia asiatica ethanol extract. J Ethnopharmacol 152(3): 487-496.
• 1919 Jiang, M., et al. (2014). Neuroprotective effects of bilobalide on cerebral ischemia and reperfusion injury are associated with inhibition of pro-inflammatory mediator production and down-regulation of JNK1/2 and p38 MAPK activation. J Neuroinflammation 11(1): 167.
• 1920 Jiang, Y., et al. (2014). Targeting Müller Cell–Derived VEGF164 to Reduce Intravitreal Neovascularization in the Rat Model of Retinopathy of Prematurity. Investigative Ophthalmology & Visual Science 55(2): 824-831
• 1921 Jo, H., et al. (2014). Sulodexide inhibits retinal neovascularization in a mouse model of oxygen-induced retinopathy. BMB Rep 47(11): 637-642.
• 1922 Julian, G. S., et al. (2014). Validation of housekeeping genes in the brains of rats submitted to chronic intermittent hypoxia, a sleep apnea model. PLOS ONE 9(10): e109902.
• 1923 Jun, J. C., et al. (2014). Intermittent hypoxia-induced glucose intolerance is abolished by α-adrenergic blockade or adrenal medullectomy. American Journal of Physiology-Endocrinology and Metabolism 307(11): E1073-E1083.
• 1924 Kaur, P., et al. (2014). Expression profiling of RNA transcripts during neuronal maturation and ischemic injury. PLOS ONE 9(7): e103525.
• 1925 Kempes, C. P., et al. (2014). Morphological optimization for access to dual oxidants in biofilms. Proc Natl Acad Sci U S A 111(1): 208-213.
• 1926 Kim, J., et al. (2014). Downregulation of metabolic activity increases cell survival under hypoxic conditions: potential applications for tissue engineering. Tissue Eng Part A 20(15-16): 2265-2272.
• 1927 Kondrikov, D., et al. (2014). Novel peptide for attenuation of hyperoxia-induced disruption of lung endothelial barrier and pulmonary edema via modulating peroxynitrite formation. J Biol Chem 289(48): 33355-33363.
• 1928Krishnappa, V., et al. (2014). FGF2 protects mouse mesenchymal stem cells from oxidative stress by modulating a twist2-p53 signaling axis. Cytotherapy 16(4): S74
• 1929 Krook, M. A., et al. (2014). Stress-induced CXCR4 promotes migration and invasion of ewing sarcoma. Mol Cancer Res 12(6): 953-964.
• 1930 Kuiper, C., et al. (2014). Intracellular ascorbate enhances hypoxia-inducible factor (HIF)-hydroxylase activity and preferentially suppresses the HIF-1 transcriptional response. Free Radic Biol Med 69: 308-317.
• 1931 Lagishetty, V., et al. (2014). Dysregulation of CLOCK gene expression in hyperoxia-induced lung injury. Am J Physiol Cell Physiol 306(11): C999-C1007.
• 1932 Lee, D., et al. (2014). Hyperoxia resensitizes chemoresistant glioblastoma cells to temozolomide through unfolded protein response. Anticancer research 34(6): 2957-2966.
• 1933 Lee, K. J., et al. (2014). Disrupted pulmonary artery cyclic guanosine monophosphate signaling in mice with hyperoxia-induced pulmonary hypertension. Am J Respir Cell Mol Biol 50(2): 369-378.
• 1934 Leithner, K., et al. (2014). Hypoxia increases membrane metallo-endopeptidase expression in a novel lung cancer ex vivo model – role of tumor stroma cells. BMC cancer 14(1): 40.
• 1935 Li, C.-H., et al. (2014). Minocycline accelerates hypoxia-inducible factor-1 alpha degradation and inhibits hypoxia-induced neovasculogenesis through prolyl hydroxylase, von Hippel–Lindau-dependent pathway. Archives of toxicology 88(3): 659-671.
• 1936 Li, D., et al. (2014). Propofol selectively inhibits nuclear factor-κB activity by suppressing p38 mitogen‑activated protein kinase signaling in human EA. hy926 endothelial cells during intermittent hypoxia/reoxygenation. Molecular medicine reports 9(4): 1460-1466.
• 1937 Lima-Ojeda, J. M., et al. (2014). Lack of protracted behavioral abnormalities following intermittent or continuous chronic mild hypoxia in perinatal C57BL/6 mice. Neurosci Lett 577: 77-82.
• 1938 Lin, H. and S. Qin (2014). Tipping points in seaweed genetic engineering: scaling up opportunities in the next decade. Mar Drugs 12(5): 3025-3045.
• 1939 Linzke, N., et al. (2014). Carbon monoxide promotes proliferation of uterine natural killer cells and remodeling of spiral arteries in pregnant hypertensive heme oxygenase-1 mutant mice. Hypertension 63(3): 580-588.
• 1940 Liu, H., et al. (2014). Proteasomal degradation of O-GlcNAc transferase elevates hypoxia-induced vascular endothelial inflammatory response. Cardiovascular research 103(1): 131-139
• 1941 Liu, L., et al. (2014). Intranasal versus Intraperitoneal Delivery of Human Umbilical Cord Tissue–Derived Cultured Mesenchymal Stromal Cells in a Murine Model of Neonatal Lung Injury. The American Journal of Pathology 184(12): 3344-3358.
• 1942 Liu, X. B., et al. (2014). Enhancement of cisplatin-based TACE by a hemoglobin-based oxygen carrier in an orthotopic rat HCC model. Artif Cells Nanomed Biotechnol 42(4): 229-236.
• 1943 Liu, Y., et al. (2014). Long-term biodistribution in vivo and toxicity of radioactive/magnetic hydroxyapatite nanorods. Biomaterials 35(10): 3348-3355.
• 1944Liu, Y.-S., et al. (2014). The expression of epidermal growth factor-like domain 7 regulated by oxygen tension via hypoxia inducible factor (HIF)-1α activity. Postgraduate medicine(0): 1-6
• 1945 Lobo, M. R., et al. (2014). Combined Efficacy of Cediranib and Quinacrine in Glioma Is Enhanced by Hypoxia and Causally Linked to Autophagic Vacuole Accumulation. PLOS ONE 9(12): e114110.
• 1946 Lottes, R. G., et al. (2014). Alveolar type II cells maintain bioenergetic homeostasis in hypoxia through metabolic and molecular adaptation. American Journal of Physiology-Lung Cellular and Molecular Physiology 306(10): L947-L955.
• 1947 Lu, M.-J., et al. (2014). Hypoxic preconditioning protects rat hearts against ischemia–reperfusion injury via the arachidonate12-lipoxygenase/transient receptor potential vanilloid 1 pathway. Basic research in cardiology 109(4): 1-14
• 1948 Lu, W., et al. (2014). Effect of intermittent hypoxia on rat INS-1 cells and the protective effect of melatonin. Eur Rev Med Pharmacol Sci 18(7): 941-948.
• 1949 Lucking, E. F., et al. (2014). Increased cardiac output contributes to the development of chronic intermittent hypoxia-induced hypertension. Exp Physiol 99(10): 1312-1324.
• 1950 Ludewig, P., et al. (2014). CEACAM1 confers resistance towards oxygen-induced vessel damage in a mouse model of retinopathy of prematurity. Investigative Ophthalmology & Visual Science: IOVS-13-13403
• 1951 Mahnke, A., et al. (2014). Hypoxia in Leishmania major skin lesions impairs the NO-dependent leishmanicidal activity of macrophages. J Invest Dermatol 134(9): 2339-2346.
• 1952 Marampon, F., et al. (2014). Hypoxia sustains glioblastoma radioresistance through ERKs/DNA-PKcs/HIF-1α functional interplay. International journal of oncology 44(6): 2121-2131.
• 1953 Marconi, G. D., et al. (2014). Postnatal hyperoxia exposure differentially affects hepatocytes and liver haemopoietic cells in newborn rats. PLOS ONE 9(8): e105005.
• 1954 Maron, B. A., et al. (2014). Upregulation of steroidogenic acute regulatory protein by hypoxia stimulates aldosterone synthesis in pulmonary artery endothelial cells to promote pulmonary vascular fibrosis. Circulation 130(2): 168-179.
• 1955 Marozkina, L. A. P., et al. (2014). Essential role of hemoglobin beta-93-cysteine in. J Appl Physiol 116: 1290-1299
• 1956 Martindale, J. J. and J. M. Metzger (2014). Uncoupling of increased cellular oxidative stress and myocardial ischemia reperfusion injury by directed sarcolemma stabilization. J Mol Cell Cardiol 67: 26-37.
• 1957 Matsubara, M., et al. (2014). Influence of the difference of breastfeeding volume on a rat model of oxygen-induced retinopathy. J Clin Biochem Nutr 55(2): 129-134.
• 1958McIntyre-Wressnig, A., et al. (2014). Ocean acidification not likely to affect the survival and fitness of two temperate benthic foraminiferal species: results from culture experiments. The Journal of Foraminiferal Research 44(4): 341-351
• 1959 McKenna, S., et al. (2014). Sustained hyperoxia-induced NF-κB activation improves survival and preserves lung development in neonatal mice. American Journal of Physiology-Lung Cellular and Molecular Physiology 306(12): L1078-L1089.
• 1960 Mei, S. H., et al. (2014). Isolation and large-scale expansion of bone marrow-derived mesenchymal stem cells with serum-free media under GMP-compliance. Cytotherapy 16(4): S111.
• 1961Mei, S. H., et al. (2014). Isolation and large-scale expansion of bone marrow-derived mesenchymal stem cells with serum-free media under GMP-compliance. mortality 40: 1
• 1962 Mendez-Sanchez, J. F. and W. W. Burggren (2014). Environmental modulation of the onset of air breathing and survival of Betta splendens and Trichopodus trichopterus. J Fish Biol 84(3): 794-807.
• 1963Mennesson, E., et al. (2014). SilenciX®, novel stable knock-down cellular models to screen new molecular targets through the synthetic lethality approach. Cancer Research 74(19 Supplement): 3733-3733
• 1964 Menon, D. R., et al. (2014). A stress-induced early innate response causes multidrug tolerance in melanoma. Oncogene
• 1965 Mezu-Ndubuisi, O. J., et al. (2014). Correspondence of retinal thinning and vasculopathy in mice with oxygen-induced retinopathy. Exp Eye Res 122: 119-122.
• 1966 Michaelis, K. A., et al. (2014). IκBβ-Mediated NF-κB Activation Confers Protection against Hyperoxic Lung Injury. American Journal of Respiratory Cell and Molecular Biology 50(2): 429-438.
• 1967 Miloudi, K., et al. (2014). Assessment of vascular regeneration in the CNS using the mouse retina. JoVE (Journal of Visualized Experiments)(88): e51351-e51351
• 1968 Miners, S., et al. (2014). Reduced vascular endothelial growth factor and capillary density in the occipital cortex in dementia with Lewy bodies. Brain Pathol 24(4): 334-343.
• 1969 Moraes, D. J., et al. (2014). Short-term sustained hypoxia induces changes in the coupling of sympathetic and respiratory activities in rats. J Physiol 592(9): 2013-2033.
• 1970 Muñoz, N., et al. (2014). Gas chromatography–mass spectrometry analysis of human mesenchymal stem cell metabolism during proliferation and osteogenic differentiation under different oxygen tensions. Journal of biotechnology 169: 95-102.
• 1971 Nagai, M., et al. (2014). Simultaneous comparison of thrombogenic reactions to different combinations of anticoagulants, activated clotting times, and materials. J Biomed Mater Res B Appl Biomater 102(8): 1605-1612.
• 1972 Nahar, K., et al. (2014). Peptide-coated liposomal fasudil enhances site specific vasodilation in pulmonary arterial hypertension. Mol Pharm 11(12): 4374-4384.
• 1973 Nakamura, S., et al. (2014). Role of metallothioneins 1 and 2 in ocular neovascularization. Invest Ophthalmol Vis Sci 55(10): 6851-6860.
• 1974 Nalwa, H. S. (2014). A special issue on reviews in biomedical applications of nanomaterials, tissue engineering, stem cells, bioimaging, and toxicity. J Biomed Nanotechnol 10(10): 2421-2423.
• 1975 Namba, F., et al. (2014). Expression level and subcellular localization of heme oxygenase-1 modulates its cytoprotective properties in response to lung injury: a mouse model. PLOS ONE 9(3): e90936.
• 1976 Nuschke, A., et al. (2014). Human mesenchymal stem cells/multipotent stromal cells consume accumulated autophagosomes early in differentiation. Stem Cell Res Ther 5(6): 140.
• 1977 Oghli, M. G., et al. (2014). Right Ventricle Functional Parameters Estimation in Arrhythmogenic Right Ventricular Dysplasia Using a Robust Shape Based Deformable Model. Journal of medical signals and sensors 4(3): 211
• 1978Papaioannou, S. (2014). Adipose-Derived Stem Cell Exosomes & Their Relevance In Regenerative Medicine. Thesis
• 1979 Peng, X., et al. (2014). Involvement of calcium-sensing receptors in hypoxia-induced vascular remodeling and pulmonary hypertension by promoting phenotypic modulation of small pulmonary arteries. Mol Cell Biochem 396(1-2): 87-98.
• 1980 Phinney, D. G. and I. A. Isakova (2014). Mesenchymal stem cells as cellular vectors for pediatric neurological disorders. Brain Res 1573: 92-107.
• 1981 Poitz, D. M., et al. (2014). Regulation of the HIF-system in human macrophages–Differential regulation of HIF-α subunits under sustained hypoxia. Molecular immunology 57(2): 226-235.
• 1982 Popova, A. P., et al. (2014). Reduced platelet-derived growth factor receptor expression is a primary feature of human bronchopulmonary dysplasia. American Journal of Physiology-Lung Cellular and Molecular Physiology 307(3): L231-L239.
• 1983 Porter, K. M., et al. (2014). Chronic Hypoxia Promotes Pulmonary Artery Endothelial Cell Proliferation through H2O2-Induced 5-Lipoxygenase. PLOS ONE 9(6): e98532.
• 1984Porzionato, A., et al. (2014). Effects of postnatal hyperoxia exposure on the rat dentate gyrus and subventricular zone. Brain Structure and Function 220(1): 229-247
• 1985 Potdar, A. A., et al. (2014). Computational modeling and analysis of iron release from macrophages. PLoS Comput Biol 10(7): e1003701.
• 1986 Prasad, M., et al. (2014). Moderate hypoxia influences potassium outward currents in adipose-derived stem cells. PLOS ONE 9(8): e104912.
• 1987 Prasain, N., et al. (2014). Differentiation of human pluripotent stem cells to cells similar to cord-blood endothelial colony-forming cells. Nat Biotechnol 32(11): 1151-1157.
• 1988 Ramchandran, R., et al. (2014). PKG1α leucine zipper domain defect increases pulmonary vascular tone: implications in hypoxic pulmonary hypertension. American Journal of Physiology-Lung Cellular and Molecular Physiology: ajplung. 00093.02014
• 1989 Rau, T. F., et al. (2014). Phenoxybenzamine Is Neuroprotective in a Rat Model of Severe Traumatic Brain Injury. International journal of molecular sciences 15(1): 1402-1417.
• 1990 Ravikumar, P., et al. (2014). alpha-Klotho protects against oxidative damage in pulmonary epithelia. Am J Physiol Lung Cell Mol Physiol 307(7): L566-575.
• 1991 Reitman, Z. J., et al. (2014). Cancer-associated isocitrate dehydrogenase 1 (IDH1) R132H mutation and d-2-hydroxyglutarate stimulate glutamine metabolism under hypoxia. J Biol Chem 289(34): 23318-23328.
• 1992 Röhrborn, D., et al. (2014). Shedding of dipeptidyl peptidase 4 is mediated by metalloproteases and up-regulated by hypoxia in human adipocytes and smooth muscle cells. FEBS letters 588(21): 3870-3877.
• 1993 Ronkainen, V.-P., et al. (2014). Hypoxia-inducible factor 1-induced G protein-coupled receptor 35 expression is an early marker of progressive cardiac remodelling. Cardiovascular research 101(1): 69-77.
• 1994 Rueda-Clausen, C. F., et al. (2014). Effect of prenatal hypoxia in transgenic mouse models of preeclampsia and fetal growth restriction. Reprod Sci 21(4): 492-502.
• 1995 Russo, V., et al. (2014). Comparison of human adipose-derived stem cells isolated from subcutaneous, omental, and intrathoracic adipose tissue depots for regenerative applications. Stem Cells Transl Med 3(2): 206-217.
• 1996 Salomon, C., et al. (2014). Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration. Front Pharmacol 5: 175.
• 1997 Sandholm, J., et al. (2014). Hypoxia regulates Toll-like receptor-9 expression and invasive function in human brain cancer cells in vitro. Oncol Lett 8(1): 266-274.
• 1998 Schmitz, T., et al. (2014). Minocycline protects the immature white matter against hyperoxia. Exp Neurol 254: 153-165.
• 1999 Schwingshackl, A., et al. (2014). Deficiency of the two-pore-domain potassium channel TREK-1 promotes hyperoxia-induced lung injury. Crit Care Med 42(11): e692-701.
• 2000 Shah, P. K., et al. (2014). Dynamics and evolution of β-catenin-dependent Wnt signaling revealed through massively parallel clonogenic screening. Integrative Biology
• 2001 Shah, P. K., et al. (2014). Small sample sorting of primary adherent cells by automated micropallet imaging and release. Cytometry A 85(7): 642-649.
• 2002 Shatat, M. A., et al. (2014). Endothelial Kruppel-like factor 4 modulates pulmonary arterial hypertension. Am J Respir Cell Mol Biol 50(3): 647-653.
• 2003 Shlyonsky, V., et al. (2014). Possible role of lysophosphatidic acid in rat model of hypoxic pulmonary vascular remodeling. Pulm Circ 4(3): 471-481.
• 2004 Shyu, K. G., et al. (2014). Hypoxia activates muscle-restricted coiled-coil protein (MURC) expression via transforming growth factor-beta in cardiac myocytes. Clin Sci (Lond) 126(5): 367-375.
• 2005 Siwetz, M., et al. (2014). Metalloprotease dependent release of placenta derived fractalkine. Mediators Inflamm 2014: 839290.
• 2006 Słomka, M., et al. (2014). NMDA receptor antagonists MK-801 and memantine induce tolerance to oxygen and glucose deprivation in primary cultures of rat cerebellar granule cells. Acta Neurobiol Exp 74: 396-404
• 2007 Sobeih, D., et al. (2014). Deletion of SPARC Enhances Retinal Vaso-Obliteration in Mouse Model of Oxygen-Induced Retinopathy. HSOA J Ophthalmol Clin Res 1(1): 2.
• 2008 Sohn, E. H., et al. (2014). Structural and biochemical analyses of choroidal thickness in human donor eyes. Invest Ophthalmol Vis Sci 55(3): 1352-1360.
• 2009 Soliman, S., et al. (2014). Candesartan induces a prolonged proangiogenic effect and augments endothelium-mediated neuroprotection after oxygen and glucose deprivation: role of vascular endothelial growth factors A and B. J Pharmacol Exp Ther 349(3): 444-457.
• 2010 Son, J.-H., et al. (2014). Melatonin promotes osteoblast differentiation and mineralization of MC3T3-E1 cells under hypoxic conditions through activation of PKD/p38 pathways. Journal of pineal research
• 2011Stimson, R. J. (2014). 1 Proximity and endogenous regional development. Regional Development and Proximity Relations: 47
• 2012 Sturrock, A., et al. (2014). Key role of microRNA in the regulation of granulocyte macrophage colony-stimulating factor expression in murine alveolar epithelial cells during oxidative stress. J Biol Chem 289(7): 4095-4105.
• 2013 Su, C. L., et al. (2014). Combined effects of maternal inflammation and neonatal hyperoxia on lung fibrosis and RAGE expression in newborn rats. Pediatr Res 75(2): 273-280.
• 2014 Su, J., et al. (2014). Raphe serotonergic neurons modulate genioglossus corticomotor activity in intermittent hypoxic rats. Respir Res 15(1): 76.
• 2015 Sullivan, E. J., et al. (2014). Targeting cisplatin-resistant human tumor cells with metabolic inhibitors. Cancer Chemother Pharmacol 73(2): 417-427.
• 2016 Suryana, E. and N. M. Jones (2014). The effects of hypoxic preconditioning on white matter damage following hypoxic-ischaemic injury in the neonatal rat brain. Int J Dev Neurosci 37: 69-75.
• 2017 Sweigard, J. H., et al. (2014). The alternative complement pathway regulates pathological angiogenesis in the retina. FASEB J 28(7): 3171-3182.
• 2018Taha, M., et al. (2014). Circulating Extracellular Micrornas In Hypoxia-Induced Pulmonary Hypertension In Mice. Am J Respir Crit Care Med 189: A3309
• 2019 Tang, H., et al. (2014). Deficiency of Akt1, but not Akt2, Attenuates the Development of Pulmonary Hypertension. American Journal of Physiology-Lung Cellular and Molecular Physiology: ajplung. 00242.02014
• 2020 Tertil, M., et al. (2014). Regulation and novel action of thymidine phosphorylase in non-small cell lung cancer: crosstalk with Nrf2 and HO-1. PLOS ONE 9(5): e97070.
• 2021Tibboel, J., et al. (2014). HIF-1 Stimulates Postnatal Lung Development but Does Not Prevent O2-induced Alveolar Injury. American Journal of Respiratory Cell and Molecular Biology(ja)
• 2022 Tjärnlund-Wolf, A., et al. (2014). Species-Specific regulation of t-PA and PAI-1 gene expression in human and rat astrocytes. Gene regulation and systems biology 8: 113.
• 2023 Toutounchian, J. J., et al. (2014). Modulation of radiation injury response in retinal endothelial cells by quinic acid derivative KZ-41 involves p38 MAPK. PLOS ONE 9(6): e100210.
• 2024 Tucker, B. A., et al. (2014). Stem cells for investigation and treatment of inherited retinal disease. Hum Mol Genet 23(R1): R9-R16.
• 2025 Vadivel, A., et al. (2014). Exogenous hydrogen sulfide (H2S) protects alveolar growth in experimental O2-induced neonatal lung injury. PLOS ONE 9(3): e90965.
• 2026 Vadivel, A., et al. (2014). Hypoxia-inducible factors promote alveolar development and regeneration. Am J Respir Cell Mol Biol 50(1): 96-105.
• 2027 Varela-Nallar, L., et al. (2014). Chronic hypoxia induces the activation of the Wnt/β-catenin signaling pathway and stimulates hippocampal neurogenesis in wild-type and APPswe-PS1ΔE9 transgenic mice in vivo. Frontiers in cellular neuroscience 8
• 2028 Viswanathan, P., et al. (2014). Human pluripotent stem cells on artificial microenvironments: a high content perspective. Front Pharmacol 5: 150.
• 2029 Vitali, S. H., et al. (2014). The Sugen 5416/hypoxia mouse model of pulmonary hypertension revisited: long-term follow-up. Pulm Circ 4(4): 619-629.
• 2030 Vlaski, M., et al. (2014). Hypoxia/Hypercapnia‐Induced Adaptation Maintains Functional Capacity of Cord Blood Stem and Progenitor Cells at 4° C. Journal of Cellular Physiology 229(12): 2153-2165.
• 2031 Vyas-Read, S., et al. (2014). Hyperoxia induces alveolar epithelial-to-mesenchymal cell transition. Am J Physiol Lung Cell Mol Physiol 306(4): L326-340.
• 2032 Wall, A. M., et al. (2014). Effects of prolyl-hydroxylase inhibition and chronic intermittent hypoxia on synaptic transmission and plasticity in the rat CA1 and dentate gyrus. Neurobiol Dis 62: 8-17.
• 2033 Wallace, K., et al. (2014). Enodthelin 1 Is Elevated in Plasma and Explants From Patients Having Uterine Leiomyomas. Reproductive Sciences 21(9): 1196-1205.
• 2034 Wang, C., et al. (2014). Preparation of laponite bioceramics for potential bone tissue engineering applications. PLOS ONE 9(6): e99585.
• 2035 Wang, H., et al. (2014). Quantitative analyses of retinal vascular area and density after different methods to reduce VEGF in a rat model of retinopathy of prematurity. Invest Ophthalmol Vis Sci 55(2): 737-744.
• 2036 Wang, L., et al. (2014). Increased leptin by hypoxic-preconditioning promotes autophagy of mesenchymal stem cells and protects them from apoptosis. Science China Life Sciences 57(2): 171-180.
• 2037 Wang, S., et al. (2014). Overexpression of FABP3 inhibits human bone marrow derived mesenchymal stem cell proliferation but enhances their survival in hypoxia. Experimental cell research 323(1): 56-65.
• 2038Wang, W., et al. (2014). The Influence Of Chronic Intermittent Hypoxia On The Corticomotor Cortex Of Genioglossus In Rats. Am J Respir Crit Care Med 189: A3900
• 2039 Weis, S., et al. (2014). Autophagy in the brain of neonates following hypoxia–ischemia shows sex-and region-specific effects. Neuroscience 256: 201-209.
• 2040 Welschoff, J., et al. (2014). RGD peptides induce relaxation of pulmonary arteries and airways via β3-integrins. The FASEB Journal 28(5): 2281-2292.
• 2041 Westwood, D. A., et al. (2014). Gastrin mediates resistance to hypoxia-induced cell death in xenografts of the human colorectal cancer cell line LoVo. Biochim Biophys Acta 1843(11): 2471-2480.
• 2042 Wilhelm, K. R., et al. (2014). Hyperoxia increases the elastic modulus of alveolar epithelial cells through Rho kinase. FEBS Journal 281(3): 957-969.
• 2043 Won, S., et al. (2014). Progesterone attenuates hemorrhagic transformation after delayed tPA treatment in an experimental model of stroke in rats: involvement of the VEGF–MMP pathway. Journal of Cerebral Blood Flow & Metabolism 34(1): 72-80
• 2044 Wu, C. P., et al. (2014). Hypoxia promotes stem-like properties of laryngeal cancer cell lines by increasing the CD133+ stem cell fraction. Int J Oncol 44(5): 1652-1660.
• 2045 Wu, M., et al. (2014). Dynamic regulation of Rad51 by E2F1 and p53 in prostate cancer cells upon drug-induced DNA damage under hypoxia. Molecular pharmacology 85(6): 866-876.
• 2046 Xiao, A. J., et al. (2014). Marine compound xyloketal B reduces neonatal hypoxic-ischemic brain injury. Mar Drugs 13(1): 29-47.
• 2047 Yagasaki, R., et al. (2014). Anti-angiogenic effects of mammalian target of rapamycin inhibitors in a mouse model of oxygen-induced retinopathy. Biol Pharm Bull 37(11): 1838-1842.
• 2048Yamada, K. Y., et al. (2014). Effect of postnatal intermittent hypoxia on locomotor activity and neuronal development in rats tested in early adulthood. Psychology & Neuroscience(AHEAD): 0-0
• 2049 Yang, G., et al. (2014). Oxidative stress and inflammation modulate rev-erbα signaling in the neonatal lung and affect circadian rhythmicity. Antioxidants & redox signaling 21(1): 17-32
• 2050 Yang, Z., et al. (2014). VEGFA activates erythropoietin receptor and enhances VEGFR2-mediated pathological angiogenesis. Am J Pathol 184(4): 1230-1239.
• 2051 Ye, P., et al. (2014). Hypoxia-induced deregulation of miR-126 and its regulative effect on VEGF and MMP-9 expression. Int J Med Sci 11(1): 17-23.
• 2052 Yu, W., et al. (2014). Cardiac shock wave therapy attenuates H9c2 myoblast apoptosis by activating the AKT signal pathway. Cell Physiol Biochem 33(5): 1293-1303.
• 2053 Yuan, X., et al. (2014). Atorvastatin attenuates myocardial remodeling induced by chronic intermittent hypoxia in rats: partly involvement of TLR-4/MYD88 pathway. Biochem Biophys Res Commun 446(1): 292-297.
• 2054 Yufit, T., et al. (2014). Topical delivery of cultured stem cells to human non-healing wounds: GMP facility development in an academic setting and FDA requirements for an IND and human testing. Curr Drug Deliv 11(5): 572-581.
• 2055 Yung, H. W., et al. (2014). Differential activation of placental unfolded protein response pathways implies heterogeneity in causation of early- and late-onset pre-eclampsia. J Pathol 234(2): 262-276.
• 2056 Zaghloul, N., et al. (2014). Overexpression of extracellular superoxide dismutase protects against brain injury induced by chronic hypoxia. PLOS ONE 9(9): e108168.
• 2057 Zaja, I., et al. (2014). Cdk1, PKCδ and calcineurin-mediated Drp1 pathway contributes to mitochondrial fission-induced cardiomyocyte death. Biochemical and biophysical research communications 453(4): 710-721.
• 2058 Zanelli, S., et al. (2014). Impact of transient acute hypoxia on the developing mouse EEG. Neurobiol Dis 68: 37-46.
• 2059 Zhang, C., et al. (2014). Peptide dendrimer-Doxorubicin conjugate-based nanoparticles as an enzyme-responsive drug delivery system for cancer therapy. Adv Healthc Mater 3(8): 1299-1308.
• 2060 Zhang, H., et al. (2014). MicroRNA-145 inhibits the growth, invasion, metastasis and angiogenesis of neuroblastoma cells through targeting hypoxia-inducible factor 2 alpha. Oncogene 33(3): 387-397
• 2061 Zhang, L., et al. (2014). Baicalin Inhibits Hypoxia-Induced Pulmonary Artery Smooth Muscle Cell Proliferation via the AKT/HIF-1α/p27-Associated Pathway. International journal of molecular sciences 15(5): 8153-8168.
• 2062 Zhang, M., et al. (2014). Lin28a protects against hypoxia/reoxygenation induced cardiomyocytes apoptosis by alleviating mitochondrial dysfunction under high glucose/high fat conditions. PLOS ONE 9(10): e110580.
• 2063 Zhao, W., et al. (2014). Mesenchymal stem cell biodistribution, migration, and homing in vivo. Stem Cells Int 2014: 292109.
• 2064Zhao, Y., et al. (2014). High-power non-enzymatic glucose biofuel cells based on three-dimensional platinum nanoclusters immobilized on multiwalled carbon nanotubes. Electrochimica Acta 145: 159-169
• 2065 Abdalla, M., et al. (2013). Akt1 mediates alpha-smooth muscle actin expression and myofibroblast differentiation via myocardin and serum response factor. J Biol Chem 288(46): 33483-33493.
• 2066 Abdelsaid, M. A., et al. (2013). Thioredoxin-interacting protein expression is required for VEGF-mediated angiogenic signal in endothelial cells. Antioxidants & redox signaling 19(18): 2199-2212
• 2067 Ahlfeld, S. K., et al. (2013). Periostin downregulation is an early marker of inhibited neonatal murine lung alveolar septation. Birth Defects Research Part A: Clinical and Molecular Teratology 97(6): 373-385.
• 2068 Alagappan, D., et al. (2013). Egr-1 is a critical regulator of EGF-receptor-mediated expansion of subventricular zone neural stem cells and progenitors during recovery from hypoxia–hypoglycemia. ASN neuro 5(3): AN20120032
• 2069 Albarracin, R., et al. (2013). 670 nm light mitigates oxygen-induced degeneration in C57BL/6 J mouse retina. BMC neuroscience 14(1): 125
• 2070 Ali, I., et al. (2013). Hypoxia preconditioning increases survival and decreases expression of Toll-like receptor 4 in pulmonary artery endothelial cells exposed to lipopolysaccharide. Pulm Circ 3(3): 578-588.
• 2071 Alibrahim, A., et al. (2013). Neuroprotective effects of volume-regulated anion channel blocker DCPIB on neonatal hypoxic-ischemic injury. Acta Pharmacol Sin 34(1): 113-118.
• 2072 Ameri, K., et al. (2013). Nuclear localization of the mitochondrial factor HIGD1A during metabolic stress. PLOS ONE 8(4): e62758.
• 2073 Angelini, D. J., et al. (2013). Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMα) in chronic hypoxia-and antigen-mediated pulmonary vascular remodeling. Respir Res 14(1)
• 2074Anna, C., et al. (2013). A rapid screening test for endocrine disrupting chemicals using primary cell culture of the marine medaka. Aquatic Toxicology 144: 50-58
• 2075 Aras, S., et al. (2013). Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2. Nucleic acids research: gks1454
• 2076 Aufradet, E., et al. (2013). Hypoxia/reoxygenation stress increases markers of vasoocclusive crisis in sickle SAD mice. Clin Hemorheol Microcirc 54(3): 297-312
• 2077 Bansal, G., et al. (2013). IL-22 activates oxidant signaling in pulmonary vascular smooth muscle cells. Cell Signal 25(12): 2727-2733.
• 2078 Bath, C. (2013). Human corneal epithelial subpopulations: oxygen dependent ex vivo expansion and transcriptional profiling. Acta Ophthalmol 91 Thesis 4(thesis4): 1-34.
• 2079 Bath, C., et al. (2013). Hypoxia is a key regulator of limbal epithelial stem cell growth and differentiation. Stem cell research 10(3): 349-360.
• 2080 Bathina, C. S., et al. (2013). Knockdown of tyrosine hydroxylase in the nucleus of the solitary tract reduces elevated blood pressure during chronic intermittent hypoxia. Am J Physiol Regul Integr Comp Physiol 305(9): R1031-1039.
• 2081 Bauer, A. J., et al. (2013). Pravastatin attenuates hypertension, oxidative stress, and angiogenic imbalance in rat model of placental ischemia-induced hypertension. Hypertension 61(5): 1103-1110.
• 2082 Baumann, G., et al. (2013). Pronounced hypoxia in the subventricular zone following traumatic brain injury and the neural stem/progenitor cell response. Exp Biol Med (Maywood) 238(7): 830-841.
• 2083 Baysal, B. E., et al. (2013). Hypoxia-inducible C-to-U coding RNA editing downregulates SDHB in monocytes. PeerJ 1: e152.
• 2084 Berger, S., et al. (2013). Endothelial progenitor cells in acute myocardial infarction and sleep-disordered breathing. Am J Respir Crit Care Med 187(1): 90-98.
• 2085 Berkelhamer, S. K., et al. (2013). Developmental differences in hyperoxia-induced oxidative stress and cellular responses in the murine lung. Free Radic Biol Med 61: 51-60.
• 2086 Bianco, C., et al. (2013). Regulation of human Cripto-1 expression by nuclear receptors and DNA promoter methylation in human embryonal and breast cancer cells. J Cell Physiol 228(6): 1174-1188.
• 2087 Blaustein, M., et al. (2013). Modulation of the Akt pathway reveals a novel link with PERK/eIF2α, which is relevant during hypoxia. PLOS ONE 8(7)
• 2088 Brill, A., et al. (2013). Hypoxia, such as encountered at high altitude, promotes deep vein thrombosis in mice. Journal of Thrombosis and Haemostasis 11(9): 1773-1775
• 2089 Cameron, J. C., et al. (2013). Biogenesis of a bacterial organelle: the carboxysome assembly pathway. Cell 155(5): 1131-1140.
• 2090 Cao, X., et al. (2013). A new approach to screening cancer stem cells from the U251 human glioma cell line based on cell growth state. Oncol Rep 29(3): 1013-1018.
• 2091 Caralla, T., et al. (2013). In vivo transplantation of autogenous marrow-derived cells following rapid intraoperative magnetic separation based on hyaluronan to augment bone regeneration. Tissue Eng Part A 19(1-2): 125-134.
• 2092 Chang, C. P., et al. (2013). Hypoxic preconditioning enhances the therapeutic potential of the secretome from cultured human mesenchymal stem cells in experimental traumatic brain injury. Clin Sci (Lond) 124(3): 165-176.
• 2093 Chang, W. W., et al. (2013). Salmonella enhance chemosensitivity in tumor through connexin 43 upregulation. International Journal of Cancer 133(8): 1926-1935
• 2094 Chaturvedi, S., et al. (2013). Slit2 prevents neutrophil recruitment and renal ischemia-reperfusion injury. J Am Soc Nephrol 24(8): 1274-1287.
• 2095 Chen, X. Q., et al. (2013). Lipoxin A4-induced heme oxygenase-1 protects cardiomyocytes against hypoxia/reoxygenation injury via p38 MAPK activation and Nrf2/ARE complex. PLOS ONE 8(6): e67120.
• 2096 Chen, X.-Q., et al. (2013). Involvement of K+ channel-dependant pathways in lipoxin A 4-induced protective effects on hypoxia/reoxygenation injury of cardiomyocytes. Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) 88(5): 391-397
• 2097 Ch’ng, W.-C., et al. (2013). The Oncolytic Activity of Newcastle Disease Virus in Clear Cell Renal Carcinoma Cells in Normoxic and Hypoxic Conditions: The Interplay Between von Hippel-Lindau and Interferon-β Signaling. Journal of Interferon & Cytokine Research 33(7): 346-354
• 2098 Choi, H. J., et al. (2013). ECM-dependent HIF induction directs trophoblast stem cell fate via LIMK1-mediated cytoskeletal rearrangement. PLOS ONE 8(2): e56949.
• 2099 Choi, J., et al. (2013). Degradome products of the matricellular protein CCN1 as modulators of pathological angiogenesis in the retina. Journal of Biological Chemistry 288(32): 23075-23089
• 2100 Chou, Y. T., et al. (2013). C/EBP homologous binding protein (CHOP) underlies neural injury in sleep apnea model. Sleep 36(4): 481-492.
• 2101 Colleoni, F., et al. (2013). Suppression of mitochondrial electron transport chain function in the hypoxic human placenta: a role for miRNA-210 and protein synthesis inhibition. PLOS ONE 8(1): e55194.
• 2102 Cordero-Espinoza, L. and T. Hagen (2013). Regulation of Cullin-RING ubiquitin ligase 1 by Spliceosome-associated protein 130 (SAP130). Biol Open 2(8): 838-844.
• 2103 Costa, K. M., et al. (2013). Acute inhibition of glial cells in the NTS does not affect respiratory and sympathetic activities in rats exposed to chronic intermittent hypoxia. Brain research 1496: 36-48
• 2104 Cullberg, K. B., et al. (2013). Resveratrol has inhibitory effects on the hypoxia-induced inflammation and angiogenesis in human adipose tissue in vitro. European Journal of Pharmaceutical Sciences 49(2): 251-257.
• 2105 Cunningham-Bussel, A., et al. (2013). Nitrite impacts the survival of Mycobacterium tuberculosis in response to isoniazid and hydrogen peroxide. MicrobiologyOpen 2(6): 901-911.
• 2106 Das, K. C. (2013). Hyperoxia decreases glycolytic capacity, glycolytic reserve and oxidative phosphorylation in MLE-12 cells and inhibits complex I and II function, but not complex IV in isolated mouse lung mitochondria. PLOS ONE 8(9): e73358
• 2107 de Theije, C. C., et al. (2013). Distinct responses of protein turnover regulatory pathways in hypoxia- and semistarvation-induced muscle atrophy. Am J Physiol Lung Cell Mol Physiol 305(1): L82-91.
• 2108 Diaz, B., et al. (2013). Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia. J Cell Biol 201(2): 279-292.
• 2109 Dick, A. S., et al. (2013). Cyclic stretch stimulates nitric oxide synthase-1-dependent peroxynitrite formation by neonatal rat pulmonary artery smooth muscle. Free Radic Biol Med 61: 310-319.
• 2110 Dietrich, A. K., et al. (2013). 17β-Estradiol increases expression of the oxidative stress response and DNA repair protein apurinic endonuclease (Ape1) in the cerebral cortex of female mice following hypoxia. The Journal of steroid biochemistry and molecular biology 138: 410-420.
• 2111 Dietrich, L. E., et al. (2013). Bacterial community morphogenesis is intimately linked to the intracellular redox state. Journal of bacteriology 195(7): 1371-1380
• 2112 Dobes, N. C., et al. (2013). Laser-based directed release of array elements for efficient collection into targeted microwells. Analyst 138(3): 831-838.
• 2113 Doran, P. M. (2013). Therapeutically important proteins from in vitro plant tissue culture systems. Curr Med Chem 20(8): 1047-1055.
• 2114 Douglas, R. M., et al. (2013). Intermittent hypoxia and hypercapnia induce pulmonary artery atherosclerosis and ventricular dysfunction in low density lipoprotein receptor deficient mice. J Appl Physiol (1985) 115(11): 1694-1704.
• 2115 Escobar, J., et al. (2013). Prolonging in utero-like oxygenation after birth diminishes oxidative stress in the lung and brain of mice pups. Redox Biol 1(1): 297-303.
• 2116 Evensen, N. A., et al. (2013). Development of a high-throughput three-dimensional invasion assay for anti-cancer drug discovery. PLOS ONE 8(12): e82811.
• 2117 Ferrazzano, P., et al. (2013). Age-dependent microglial activation in immature brains after hypoxia- ischemia. CNS Neurol Disord Drug Targets 12(3): 338-349.
• 2118 Foldager, C. B. (2013). Advances in autologous chondrocyte implantation and related techniques for cartilage repair. Dan Med J 60(4): B4600.
• 2119 Frazier, T. P., et al. (2013). Impact of low oxygen on the secretome of human adipose-derived stromal/stem cell primary cultures. Biochimie 95(12): 2286-2296.
• 2120 Fukumoto, J., et al. (2013). NLRP3 deletion protects from hyperoxia-induced acute lung injury. Am J Physiol Cell Physiol 305(2): C182-189.
• 2121 Gates, K. L., et al. (2013). Hypercapnia impairs lung neutrophil function and increases mortality in murine pseudomonas pneumonia. Am J Respir Cell Mol Biol 49(5): 821-828.
• 2122 Geng, X., et al. (2013). Reduced apoptosis by combining normobaric oxygenation with ethanol in transient ischemic stroke. Brain Res 1531: 17-24.
• 2123 Geng, X., et al. (2013). Synergetic neuroprotection of normobaric oxygenation and ethanol in ischemic stroke through improved oxidative mechanism. Stroke 44(5): 1418-1425
• 2124 Gerez, J., et al. (2013). In silico structural and functional characterization of the RSUME splice variants. PLOS ONE 8(2): e57795.
• 2125 Ghatnekar, A., et al. (2013). Endothelial GATA-6 deficiency promotes pulmonary arterial hypertension. Am J Pathol 182(6): 2391-2406.
• 2126 Ghosh, P., et al. (2013). Biological safety assessment of mutant variant of Allium sativum leaf agglutinin (mASAL), a novel antifungal protein for future transgenic application. J Agric Food Chem 61(48): 11858-11864.
• 2127 Ghosh, S., et al. (2013). Extracellular hemin crisis triggers acute chest syndrome in sickle mice. J Clin Invest 123(11): 4809-4820.
• 2128 Gordon, L., et al. (2013). EMP2 regulates angiogenesis in endometrial cancer cells through induction of VEGF. Oncogene 32(46): 5369-5376.
• 2129 Gortner, L., et al. (2013). Bronchopulmonary dysplasia in a double-hit mouse model induced by intrauterine hypoxia and postnatal hyperoxia: closer to clinical features? Ann Anat 195(4): 351-358.
• 2130 Graham, B. B., et al. (2013). Transforming growth factor-beta signaling promotes pulmonary hypertension caused by Schistosoma mansoni. Circulation 128(12): 1354-1364.
• 2131 Grisafi, D., et al. (2013). Human amniotic fluid stem cells protect rat lungs exposed to moderate hyperoxia. Pediatr Pulmonol 48(11): 1070-1080.
• 2132 Guo, X. L., et al. (2013). ERK signaling mediates enhanced angiotensin II-induced rat aortic constriction following chronic intermittent hypoxia. Chin Med J (Engl) 126(17): 3251-3258.
• 2133 Gutierrez, D. V., et al. (2013). Intermittent hypoxia training after C2 hemisection modifies the expression of PTEN and mTOR. Exp Neurol 248: 45-52.
• 2134 Hamilton, T. K., et al. (2013). Potential therapeutic applications of phosphodiesterase inhibition in prostate cancer. World J Urol 31(2): 325-330.
• 2135 Han, Q., et al. (2013). Intermittent hypoxia-induced NF-κB and HO-1 regulation in human endothelial EA. hy926 cells. Cell biochemistry and biophysics 66(3): 431-441
• 2136 Hein, M. and S. Graver (2013). Tumor cell response to bevacizumab single agent therapy in vitro. Cancer Cell Int 13(1): 94.
• 2137Herr, K. B., et al. (2013). Metabolic effects of intermittent hypoxia in mice. Am J Physiol Regul Integr Comp Physiol 304(7): R514-R522
• 2138 Herr, K. B., et al. (2013). Reduced c-Fos expression in medullary catecholaminergic neurons in rats 20 h after exposure to chronic intermittent hypoxia. Am J Physiol Regul Integr Comp Physiol 304(7): R514-522.
• 2139 Hewing, N. J., et al. (2013). Intravitreal injection of TIMP3 or the EGFR inhibitor erlotinib offers protection from oxygen-induced retinopathy in mice. Invest Ophthalmol Vis Sci 54(1): 864-870.
• 2140 Heylman, C. M., et al. (2013). Slowing the Onset of Hypoxia Increases Colony Forming Efficiency of Connective Tissue Progenitor Cells In Vitro. J Regen Med Tissue Eng 2.
• 2141 Hofmann, J., et al. (2013). Ratiometric luminescence 2D in vivo imaging and monitoring of mouse skin oxygenation. Methods Appl Fluoresc 1(4): 045002.
• 2142 Holm, J. B., et al. (2013). Volume-sensitive release of organic osmolytes in the human lung epithelial cell line A549: role of the 5-lipoxygenase. Am J Physiol Cell Physiol 305(1): C48-60.
• 2143 Hsieh, I. S., et al. (2013). Upregulation of drug transporter expression by osteopontin in prostate cancer cells. Mol Pharmacol 83(5): 968-977.
• 2144 Hsu, C. S., et al. (2013). Response to stress in early tumor colonization modulates switching of CD133-positive and CD133-negative subpopulations in a human metastatic colon cancer cell line, SW620. PLOS ONE 8(4): e61133.
• 2145Huppertz, N. D., et al. (2013). Characterization of urinary bladder function in Göttingen Minipigs (GM) monitored by radiotelemetric natural filling cystometry (CM): Non-micturition-associated (NM) and micturition-associated (MI) detrusor events. The Journal of Urology 189(4S)
• 2146 Ibe, J. C. F., et al. (2013). Adenosine Monophosphate–Activated Protein Kinase Is Required for Pulmonary Artery Smooth Muscle Cell Survival and the Development of Hypoxic Pulmonary Hypertension. American Journal of Respiratory Cell and Molecular Biology 49(4): 609-618.
• 2147 Israelsen, W. J., et al. (2013). PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells. Cell 155(2): 397-409.
• 2148 Ito, T., et al. (2013). Girdin and its phosphorylation dynamically regulate neonatal vascular development and pathological neovascularization in the retina. Am J Pathol 182(2): 586-596.
• 2149 Jaeger, A. A., et al. (2013). Microfabricated polymeric vessel mimetics for 3-D cancer cell culture. Biomaterials 34(33): 8301-8313.
• 2150 Jaussaud, J., et al. (2013). Hypoxia-preconditioned mesenchymal stromal cells improve cardiac function in a swine model of chronic myocardial ischaemia. Eur J Cardiothorac Surg 43(5): 1050-1057.
• 2151 Kameda, S. R., et al. (2013). Opposite effects of neonatal hypoxia on acute amphetamine-induced hyperlocomotion in adult and adolescent mice. Psychiatry Res 208(1): 74-77.
• 2152 Kan, C.-Y., et al. (2013). Up-regulation of Survivin during Immortalization of Human Myofibroblasts Is Linked to Repression of Tumor Suppressor p16INK4a Protein and Confers Resistance to Oxidative Stress. Journal of Biological Chemistry 288(17): 12032-12041.
• 2153 Kang, B. Y., et al. (2013). Hypoxia mediates mutual repression between microRNA-27a and PPARgamma in the pulmonary vasculature. PLOS ONE 8(11): e79503.
• 2154 Kawedia, J. D., et al. (2013). Hypoxia and hypoxia mimetics decrease aquaporin 5 (AQP5) expression through both hypoxia inducible factor-1alpha and proteasome-mediated pathways. PLOS ONE 8(3): e57541
• 2155 Keenaghan, M., et al. (2013). Response of vascular endothelial growth factor and angiogenesis-related genes to stepwise increases in inspired oxygen in neonatal rat lungs. Pediatr Res 73(5): 630-638.
• 2156 Kim, E. J., et al. (2013). Response of bone marrow derived connective tissue progenitor cell morphology and proliferation on geometrically modulated microtextured substrates. Biomed Microdevices 15(3): 385-396.
• 2157 Kim, I., et al. (2013). Perinatal hyperoxia exposure impairs hypoxia-induced depolarization in rat carotid body glomus cells. Respir Physiol Neurobiol 188(1): 9-14.
• 2158 Kim, J. and T. Ma (2013). Autocrine fibroblast growth factor 2‐mediated interactions between human mesenchymal stem cells and the extracellular matrix under varying oxygen tension. Journal of cellular biochemistry 114(3): 716-727.
• 2159 Kim, J. and T. Ma (2013). Endogenous extracellular matrices enhance human mesenchymal stem cell aggregate formation and survival. Biotechnol Prog 29(2): 441-451.
• 2160 King, T. L., et al. (2013). Acute systemic hypoxia activates hypothalamic paraventricular nucleus-projecting catecholaminergic neurons in the caudal ventrolateral medulla. Am J Physiol Regul Integr Comp Physiol 305(10): R1112-1123.
• 2161Klein, O. D., et al. (2013). The society of craniofacial genetics and developmental biology 35th annual meeting. American Journal of Medical Genetics Part A 161(12): 2938-2952
• 2162Köhler, S. E., et al. (2013). Characterization of the inflammatory and metabolic. J Appl Physiol 114: 1619-1628
• 2163Kommuguri, U. N., et al. (2013). Role of mitochondrial respiration in sensitization of copper-deficient yeast to cisplatin-induced cytotoxicity. Frontiers in Life Science 7(3-4): 210-217
• 2164 Konsavage, W. M., et al. (2013). Hyperoxia-induced alterations in the pulmonary proteome of juvenile rats. Exp Lung Res 39(2): 107-117.
• 2165 Krause, B. J., et al. (2013). Endothelial eNOS/arginase imbalance contributes to vascular dysfunction in IUGR umbilical and placental vessels. Placenta 34(1): 20-28.
• 2166 Krishnappa, V., et al. (2013). The peculiar biology of mouse mesenchymal stromal cells–oxygen is the key. Cytotherapy 15(5): 536-541.
• 2167 Lai, A. Y., et al. (2013). Distinct activation profiles in microglia of different ages: a systematic study in isolated embryonic to aged microglial cultures. Neuroscience 254: 185-195.
• 2168 Lai, W. H., et al. (2013). Attenuation of hind-limb ischemia in mice with endothelial-like cells derived from different sources of human stem cells. PLOS ONE 8(3): e57876.
• 2169 Lee, H. S. and C. K. Kim (2013). Interleukin-10 down-regulates cathepsin B expression in fetal rat alveolar type II cells exposed to hyperoxia. Yonsei Med J 54(2): 445-452.
• 2170Lee, H.-S. (2013). Effect of short-term exposure of different concentrations of hyperoxia on fetal alveolar type II cell death. Neonatal Medicine 20(2): 199-206
• 2171 Lee, J., et al. (2013). Angiopoietin-1 guides directional angiogenesis through integrin αvβ5 signaling for recovery of ischemic retinopathy. Science translational medicine 5(203): 203ra127-203ra127.
• 2172 Leijten, J. C., et al. (2013). GREM1, FRZB and DKK1 mRNA levels correlate with osteoarthritis and are regulated by osteoarthritis-associated factors. Arthritis Res Ther 15(5): R126.
• 2173 Leucker, T. M., et al. (2013). Impairment of endothelial-myocardial interaction increases the susceptibility of cardiomyocytes to ischemia/reperfusion injury. PLOS ONE 8(7): e70088.
• 2174 Li, H., et al. (2013). Influence of hypoxia in the intervertebral disc on the biological behaviors of rat adipose-and nucleus pulposus-derived mesenchymal stem cells. Cells Tissues Organs 198(4): 266-277
• 2175 Li, X., et al. (2013). NOD2 deficiency protects against cardiac remodeling after myocardial infarction in mice. Cell Physiol Biochem 32(6): 1857-1866.
• 2176 Lin, C., et al. (2013). Silibinin inhibits VEGF secretion and age‐related macular degeneration in a hypoxia‐dependent manner through the PI‐3 kinase/Akt/mTOR pathway. British Journal of Pharmacology 168(4): 920-931.
• 2177 Lirdprapamongkol, K., et al. (2013). A flavonoid chrysin suppresses hypoxic survival and metastatic growth of mouse breast cancer cells. Oncol Rep 30(5): 2357-2364.
• 2178 Liu, F. J., et al. (2013). microRNAs Involved in Regulating Spontaneous Recovery in Embolic Stroke Model. PLOS ONE 8(6): e66393.
• 2179 Liu, J., et al. (2013). Notch1 is a 5-fluorouracil resistant and poor survival marker in human esophagus squamous cell carcinomas. PLOS ONE 8(2): e56141.
• 2180 Lu, C., et al. (2013). The role of oxygen during fracture healing. Bone 52(1): 220-229.
• 2181Lu, Q., et al. (2013). Ca (2)(+)/calmodulin-dependent protein kinase II contributes to hypoxic ischemic cell death in neonatal hippocampal slice cultures. PLOS ONE 8: e70750
• 2182 Lu, X., et al. (2013). Hypoxia downregulates PPARγ via an ERK1/2–NF-κB–Nox4-dependent mechanism in human pulmonary artery smooth muscle cells. Free Radical Biology and Medicine 63: 151-160
• 2183 Lu, Y., et al. (2013). Synergistic regulation of hyphal elongation by hypoxia, CO(2), and nutrient conditions controls the virulence of Candida albicans. Cell Host Microbe 14(5): 499-509.
• 2184 Luo, J., et al. (2013). TCF7L2 variation and proliferative diabetic retinopathy. Diabetes 62(7): 2613-2617.
• 2185 Manley, E., Jr. and D. J. Waxman (2013). Impact of tumor blood flow modulation on tumor sensitivity to the bioreductive drug banoxantrone. J Pharmacol Exp Ther 344(2): 368-377.
• 2186 Mao, X., et al. (2013). N-acetylcysteine and allopurinol confer synergy in attenuating myocardial ischemia injury via restoring HIF-1alpha/HO-1 signaling in diabetic rats. PLOS ONE 8(7): e68949.
• 2187 Markway, B. D., et al. (2013). Hypoxia promotes redifferentiation and suppresses markers of hypertrophy and degeneration in both healthy and osteoarthritic chondrocytes. Arthritis research & therapy 15(4): R92
• 2188 Marwick, J. A., et al. (2013). Oxygen levels determine the ability of glucocorticoids to influence neutrophil survival in inflammatory environments. J Leukoc Biol 94(6): 1285-1292.
• 2189 Matoba, K., et al. (2013). Rho-kinase inhibition prevents the progression of diabetic nephropathy by downregulating hypoxia-inducible factor 1α. Kidney international 84(3): 545-554
• 2190 McCloskey, M., et al. (2013). Anti-VEGF antibody leads to later atypical intravitreous neovascularization and activation of angiogenic pathways in a rat model of retinopathy of prematurity. Invest Ophthalmol Vis Sci 54(3): 2020-2026.
• 2191McCloskey, M., et al. (2013). Knockdown of Mueller cell specific VEGF reduces retinal neovascularization in a rat model of retinopathy of prematurity (ROP). Investigative Ophthalmology & Visual Science 54(15): 621-621
• 2192 Mendel, T. A., et al. (2013). Pericytes derived from adipose-derived stem cells protect against retinal vasculopathy. PLOS ONE 8(5): e65691.
• 2193 Mezu-Ndubuisi, O. J., et al. (2013). In vivo retinal vascular oxygen tension imaging and fluorescein angiography in the mouse model of oxygen-induced retinopathy. Invest Ophthalmol Vis Sci 54(10): 6968-6972.
• 2194 Miyake, M., et al. (2013). Erythropoietin is a JAK2 and ERK1/2 effector that can promote renal tumor cell proliferation under hypoxic conditions. J Hematol Oncol 6(1): 65
• 2195 Mizrahi, O., et al. (2013). Nucleus pulposus degeneration alters properties of resident progenitor cells. Spine J 13(7): 803-814.
• 2196 Morken, T. S., et al. (2013). Brain development after neonatal intermittent hyperoxia-hypoxia in the rat studied by longitudinal MRI and immunohistochemistry. PLOS ONE 8(12): e84109.
• 2197 Mouraret, N., et al. (2013). Activation of lung p53 by Nutlin-3a prevents and reverses experimental pulmonary hypertension. Circulation 127(16): 1664-1676.
• 2198 Nair, D., et al. (2013). Growth hormone releasing hormone (GHRH) signaling modulates intermittent hypoxia-induced oxidative stress and cognitive deficits in mouse. J Neurochem 127(4): 531-540.
• 2199 Nakamura, S., et al. (2013). Mild endoplasmic reticulum stress promotes retinal neovascularization via induction of BiP/GRP78. PLOS ONE 8(3): e60517.
• 2200 Natoli, R., et al. (2013). 670nm Photobiomodulation as a Novel Protection against Retinopathy of Prematurity: Evidence from Oxygen Induced Retinopathy Models. PLOS ONE 8(8): e72135.
• 2201Nedungadi, T. P., et al. (2013). Intermittent hypoxia in vitro reduces TRPC4 and neuropeptide expression in 4B cells. The FASEB Journal 27(1_MeetingAbstracts): 699.617
• 2202 Ni, J., et al. (2013). The role of RhoA and cytoskeleton in myofibroblast transformation in hyperoxic lung fibrosis. Free Radic Biol Med 61: 26-39.
• 2203 Orabi, H., et al. (2013). Tissue engineering of urinary bladder and urethra: advances from bench to patients. ScientificWorldJournal 2013: 154564.
• 2204Palumbo, S., et al. (2013). Macrophage Migration Inhibitory Factor Regulates AKT Signaling in Hypoxic Culture to Modulate Senescence of Human Mesenchymal Stem Cells. Stem cells and development 23(8): 852-865
• 2205 Park, S., et al. (2013). Endoglin regulates the activation and quiescence of endothelium by participating in canonical and non-canonical TGF-beta signaling pathways. J Cell Sci 126(Pt 6): 1392-1405.
• 2206 Parker, E., et al. (2013). Low oxygen tension increased fibronectin fragment induced catabolic activities–response prevented with biomechanical signals. Arthritis Res Ther 15(5): R163.
• 2207 Patel, V. S., et al. (2013). High Mobility Group Box–1 Mediates Hyperoxia-Induced Impairment of Pseudomonas aeruginosa Clearance and Inflammatory Lung Injury in Mice. American Journal of Respiratory Cell and Molecular Biology 48(3): 280-287.
• 2208 Pattappa, G., et al. (2013). Continuous and uninterrupted oxygen tension influences the colony formation and oxidative metabolism of human mesenchymal stem cells. Tissue Eng Part C Methods 19(1): 68-79.
• 2209 Phinney, D. G. and L. Sensebe (2013). Mesenchymal stromal cells: misconceptions and evolving concepts. Cytotherapy 15(2): 140-145.
• 2210 Phinney, D. G., et al. (2013). MSCs: science and trials. Nat Med 19(7): 812.
• 2211 Pierro, M., et al. (2013). Short-term, long-term and paracrine effect of human umbilical cord-derived stem cells in lung injury prevention and repair in experimental bronchopulmonary dysplasia. Thorax 68(5): 475-484.
• 2212 Popescu, C. R., et al. (2013). Hyperoxia Exposure Impairs Nephrogenesis in the Neonatal Rat: Role of HIF-1α. PLOS ONE 8(12): e82421.
• 2213 Porter, K. M., et al. (2013). Human immunodeficiency virus-1 transgene expression increases pulmonary vascular resistance and exacerbates hypoxia-induced pulmonary hypertension development. Pulm Circ 3(1): 58-67.
• 2214 Portwood, S., et al. (2013). Activity of the hypoxia-activated prodrug, TH-302, in preclinical human acute myeloid leukemia models. Clin Cancer Res 19(23): 6506-6519.
• 2215 Porzionato, A., et al. (2013). Cyclosporine and hyperoxia-induced lung damage in neonatal rats. Respir Physiol Neurobiol 187(1): 41-46.
• 2216 Price, M., et al. (2013). Effects of the oxygenation level on formation of different reactive oxygen species during photodynamic therapy. Photochem Photobiol 89(3): 683-686.
• 2217 Pyo, S.-J., et al. (2013). Low-level laser therapy induces the expressions of BMP-2, osteocalcin, and TGF-β1 in hypoxic-cultured human osteoblasts. Lasers in medical science 28(2): 543-550
• 2218 Radom-Aizik, S., et al. (2013). Growth inhibition and compensation in response to neonatal hypoxia in rats. Pediatr Res 74(2): 111-120.
• 2219 Rafikova, O., et al. (2013). Bosentan inhibits oxidative and nitrosative stress and rescues occlusive pulmonaryhypertension. Free Radical Biology and Medicine 56: 28-43
• 2220 Ranasinghe, W., et al. (2013). The role of hypoxia-inducible factor 1α in determining the properties of castrate-resistant prostate cancers. PLOS ONE 8(1): e54251
• 2221 Ravi, Y., et al. (2013). Dysregulation of PTEN in cardiopulmonary vascular remodeling induced by pulmonary hypertension. Cell Biochem Biophys 67(2): 363-372.
• 2222 Ren, D., et al. (2013). SR-A deficiency reduces myocardial ischemia/reperfusion injury; involvement of increased microRNA-125b expression in macrophages. Biochim Biophys Acta 1832(2): 336-346.
• 2223 Rentea, R. M., et al. (2013). Enteral intestinal alkaline phosphatase administration in newborns decreases iNOS expression in a neonatal necrotizing enterocolitis rat model. J Pediatr Surg 48(1): 124-128.
• 2224 Riggle, K. M., et al. (2013). Intestinal alkaline phosphatase prevents the systemic inflammatory response associated with necrotizing enterocolitis. J Surg Res 180(1): 21-26.
• 2225 Rodrigues, M., et al. (2013). Surface tethered epidermal growth factor protects proliferating and differentiating multipotential stromal cells from FasL-induced apoptosis. Stem Cells 31(1): 104-116.
• 2226 Rodriguez, M., et al. (2013). Worms under stress: C. elegans stress response and its relevance to complex human disease and aging. Trends Genet 29(6): 367-374.
• 2227 Rosenberg, J. T., et al. (2013). Magnetic resonance contrast and biological effects of intracellular superparamagnetic iron oxides on human mesenchymal stem cells with long-term culture and hypoxic exposure. Cytotherapy 15(3): 307-322.
• 2228 Ryou, M. G., et al. (2013). Pyruvate minimizes rtPA toxicity from in vitro oxygen-glucose deprivation and reoxygenation. Brain Res 1530: 66-75.
• 2229 Salomon, C., et al. (2013). Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. PLOS ONE 8(7): e68451.
• 2230 Salomon, C., et al. (2013). Hypoxia-induced changes in the bioactivity of cytotrophoblast-derived exosomes. PLOS ONE 8(11): e79636.
• 2231 Santos, E., et al. (2013). Therapeutic cell encapsulation: ten steps towards clinical translation. J Control Release 170(1): 1-14.
• 2232 Saxena, S., et al. (2013). Generation of murine sympathoadrenergic progenitor-like cells from embryonic stem cells and postnatal adrenal glands. PLOS ONE 8(5): e64454.
• 2233 Schaafhausen, M. K., et al. (2013). Tumor angiogenesis is caused by single melanoma cells in a manner dependent on reactive oxygen species and NF-κB. Journal of cell science 126(17): 3862-3872
• 2234 Schrobback, K., et al. (2013). Stage-specific embryonic antigen-4 is not a marker for chondrogenic and osteogenic potential in cultured chondrocytes and mesenchymal progenitor cells. Tissue Engineering Part A 19(11-12): 1316-1326
• 2235 Sen, A., et al. (2013). MicroRNA-138 regulates hypoxia-induced endothelial cell dysfunction by targeting S100A1. PLOS ONE 8(11): e78684.
• 2236 Serrano-Saiz, E., et al. (2013). Modular control of glutamatergic neuronal identity in C. elegans by distinct homeodomain proteins. Cell 155(3): 659-673.
• 2237 Shafy, A., et al. (2013). Development of cardiac support bioprostheses for ventricular restoration and myocardial regeneration. Eur J Cardiothorac Surg 43(6): 1211-1219.
• 2238 Shang, J., et al. (2013). Ang II type 1 receptor expression in rat aorta exposed to chronic intermittent hypoxia: effects of p38MAPK and ERK1/2 signaling. Chin Med J (Engl) 126(17): 3264-3269.
• 2239 Shepardson, K. M., et al. (2013). Hypoxia enhances innate immune activation to< i> Aspergillus fumigatus through cell wall modulation. Microbes and Infection 15(4): 259-269.
• 2240 Smith, F., et al. (2013). The effect of hypoxia on facial shape variation and disease phenotypes in chicken embryos. Dis Model Mech 6(4): 915-924.
• 2241Sun, W., et al. (2013). Intermittent Hypoxia-Induced Renal Antioxidants and Oxidative Damage in Male Mice: Hormetic Dose Response. Dose-Response 11(3): 385-400
• 2242 Sweet, R. L. and J. A. Zastre (2013). HIF1-α-Mediated Gene Expression Induced by Vitamin B 1 Deficiency. International Journal for Vitamin and Nutrition Research 83(3): 188-197.
• 2243 Tache, V., et al. (2013). Hypoxia and trophoblast differentiation: a key role for PPARγ. Stem cells and development 22(21): 2815-2824.
• 2244 Tan, C. Y. and T. Hagen (2013). Destabilization of CDC6 upon DNA damage is dependent on neddylation but independent of Cullin E3 ligases. The international journal of biochemistry & cell biology 45(7): 1489-1498
• 2245 Tan, C. Y. and T. Hagen (2013). Post-translational regulation of mTOR complex 1 in hypoxia and reoxygenation. Cell Signal 25(5): 1235-1244.
• 2246 Tan, S., et al. (2013). Mycobacterium tuberculosis responds to chloride and pH as synergistic cues to the immune status of its host cell. PLoS pathog 9(4): e1003282
• 2247 Tan, X., et al. (2013). Melatonin attenuates hippocampal neuron apoptosis and oxidative stress during chronic intermittent hypoxia via up-regulating B-cell lymphoma-2 and down-regulating B-cell lymphoma-2-associated X protein. Saudi Med J 34(7): 701-708.
• 2248 Tang, Z., et al. (2013). c-Src and neural Wiskott-Aldrich syndrome protein (N-WASP) promote low oxygen-induced accelerated brain invasion by gliomas. PLOS ONE 8(9): e75436.
• 2249 Thompson, E. M., et al. (2013). Inhibiting αv Integrins Decreases the Malignant Characteristics of Medulloblastoma. Journal of neurosurgery. Pediatrics 11(1): 60.
• 2250 Thompson, E. M., et al. (2013). The effect of alpha-v integrin inhibition on the malignant characteristics of medulloblastoma. J Neurosurg Pediatr 11(1): 60-67.
• 2251 Tian, X., et al. (2013). Effect of delta-opioid receptor activation on BDNF-TrkB vs. TNF-alpha in the mouse cortex exposed to prolonged hypoxia. Int J Mol Sci 14(8): 15959-15976.
• 2252 Tibboel, J., et al. (2013). Amelioration of hyperoxia-induced lung injury using a sphingolipid-based intervention. European Respiratory Journal 42(3): 776-784.
• 2253 Trichonas, G., et al. (2013). Prolyl hydroxylase inhibition during hyperoxia prevents oxygen-induced retinopathy in the rat 50/10 model. Invest Ophthalmol Vis Sci 54(7): 4919-4926.
• 2254 Tsai, I. L., et al. (2013). Metabolomic Dynamic Analysis of Hypoxia in MDA-MB-231 and the Comparison with Inferred Metabolites from Transcriptomics Data. Cancers (Basel) 5(2): 491-510.
• 2255 Tse, A. C., et al. (2013). A rapid screening test for endocrine disrupting chemicals using primary cell culture of the marine medaka. Aquatic Toxicology 144: 50-58.
• 2256 Tucker, B. A., et al. (2013). Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa. eLife 2: e00824
• 2257 Tuomela, J., et al. (2013). Chloroquine has tumor‑inhibitory and tumor‑promoting effects in triple‑negative breast cancer. Oncology letters 6(6): 1665-1672.
• 2258 Uluc, K., et al. (2013). TrkB receptor agonist 7, 8 dihydroxyflavone triggers profound gender- dependent neuroprotection in mice after perinatal hypoxia and ischemia. CNS Neurol Disord Drug Targets 12(3): 360-370.
• 2259 Urao, N. and M. Ushio-Fukai (2013). Redox regulation of stem/progenitor cells and bone marrow niche. Free Radic Biol Med 54: 26-39.
• 2260 Vadivel, A., et al. (2013). The axonal guidance cue semaphorin 3C contributes to alveolar growth and repair. PLOS ONE 8(6): e67225.
• 2261 van den Borst, B., et al. (2013). Characterization of the inflammatory and metabolic profile of adipose tissue in a mouse model of chronic hypoxia. J Appl Physiol (1985) 114(11): 1619-1628.
• 2262 Vavilala, D. T., et al. (2013). Honokiol inhibits pathological retinal neovascularization in oxygen-induced retinopathy mouse model. Biochem Biophys Res Commun 438(4): 697-702.
• 2263 Veasey, S. C., et al. (2013). Long-term intermittent hypoxia elevates cobalt levels in the brain and injures white matter in adult mice. Sleep 36(10): 1471-1481.
• 2264 Wang, H., et al. (2013). Short hairpin RNA-mediated knockdown of VEGFA in Muller cells reduces intravitreal neovascularization in a rat model of retinopathy of prematurity. Am J Pathol 183(3): 964-974.
• 2265 Wang, J., et al. (2013). Effects of endothelial progenitor cell-derived microvesicles on hypoxia/reoxygenation-induced endothelial dysfunction and apoptosis. Oxid Med Cell Longev 2013: 572729.
• 2266 Wang, X., et al. (2013). Increased expression of microRNA-146a decreases myocardial ischaemia/reperfusion injury. Cardiovasc Res 97(3): 432-442.
• 2267 Ward, C. L., et al. (2013). Oxygen generating biomaterials preserve skeletal muscle homeostasis under hypoxic and ischemic conditions. PLOS ONE 8(8): e72485.
• 2268 Wei, N., et al. (2013). Delayed intranasal delivery of hypoxic-preconditioned bone marrow mesenchymal stem cells enhanced cell homing and therapeutic benefits after ischemic stroke in mice. Cell Transplant 22(6): 977-991.
• 2269 Weichelt, U., et al. (2013). Prevention of hyperoxia-mediated pulmonary inflammation in neonatal rats by caffeine. Eur Respir J 41(4): 966-973.
• 2270 Wu, C., et al. (2013). Opposing influence of intracellular and membrane thiols on the toxicity of reducible polycations. Biomaterials 34(34): 8843-8850.
• 2271 Xi, H., et al. (2013). Endoplasmic reticulum stress induced by 2-deoxyglucose but not glucose starvation activates AMPK through CaMKKβ leading to autophagy. Biochemical pharmacology 85(10): 1463-1477
• 2272 Yamamoto, K., et al. (2013). Resetting of the sympathetic baroreflex is associated with the onset of hypertension during chronic intermittent hypoxia. Autonomic Neuroscience 173(1): 22-27
• 2273 Yen, L. C., et al. (2013). Neurovirulent flavivirus can be attenuated in mice by incorporation of neuron-specific microRNA recognition elements into viral genome. Vaccine 31(49): 5915-5922.
• 2274 Yoo, H. Y. and S. J. Kim (2013). Disappearance of hypoxic pulmonary vasoconstriction and o2-sensitive nonselective cationic current in arterial myocytes of rats under ambient hypoxia. Korean J Physiol Pharmacol 17(5): 463-468.
• 2275 Yu, L.-X., et al. (2013). The Notch1/cyclooxygenase-2/Snail/E-cadherin pathway is associated with hypoxia-induced hepatocellular carcinoma cell invasion and migration. Oncology reports 29(1): 362-370
• 2276 Yzydorczyk, C., et al. (2013). Developmental programming of eNOS uncoupling and enhanced vascular oxidative stress in adult rats after transient neonatal oxygen exposure. J Cardiovasc Pharmacol 61(1): 8-16.
• 2277 Zara, S., et al. (2013). NF-κB involvement in hyperoxia-induced myocardial damage in newborn rat hearts. Histochemistry and cell biology 140(5): 575-583
• 2278 Zhang, N., et al. (2013). The Rat With Oxygen-Induced Retinopathy Is Myopic With Low Retinal Dopamine. Investigative Ophthalmology & Visual Science 54(13): 8275-8284
• 2279 Zhang, S., et al. (2013). Distinct post-transcriptional regulation of Igfbp1 gene by hypoxia in lowland mouse and Qinghai-Tibet plateau root vole Microtus oeconomus. Mol Cell Endocrinol 376(1-2): 33-42.
• 2280 Abbasi, A., et al. (2012). Myocardial macronutrient transporter adaptations in the adult pregestational female intrauterine and postnatal growth-restricted offspring. Am J Physiol Endocrinol Metab 302(11): E1352-1362.
• 2281 Abdel-Wahab, B. A. and S. M. Abd El-Aziz (2012). Ginkgo biloba protects against intermittent hypoxia-induced memory deficits and hippocampal DNA damage in rats. Phytomedicine 19(5): 444-450.
• 2282 Abid, S., et al. (2012). Inhibition of gut- and lung-derived serotonin attenuates pulmonary hypertension in mice. Am J Physiol Lung Cell Mol Physiol 303(6): L500-508.
• 2283 Ahmed, M. N., et al. (2012). Extracellular superoxide dismutase overexpression can reverse the course of hypoxia-induced pulmonary hypertension. Molecular Medicine 18(1): 38
• 2284 Akeel, S., et al. (2012). Recombinant bone morphogenetic protein-2 induces up-regulation of vascular endothelial growth factor and interleukin 6 in human pre-osteoblasts: role of reactive oxygen species. Arch Oral Biol 57(5): 445-452.
• 2285 Almado, C. E., et al. (2012). Chronic intermittent hypoxia depresses afferent neurotransmission in NTS neurons by a reduction in the number of active synapses. J Neurosci 32(47): 16736-16746.
• 2286 An, X., et al. (2012). Endothelial Cells Require Related Transcription Enhancer Factor-1 for Cell–Cell Connections Through the Induction of Gap Junction Proteins. Arteriosclerosis, thrombosis, and vascular biology 32(8): 1951-1959
• 2287 Azad, P., et al. (2012). Identification of genes underlying hypoxia tolerance in Drosophila by a P-element screen. G3 (Bethesda) 2(10): 1169-1178.
• 2288 Ball, K. A., et al. (2012). Nitric oxide produced by cytochrome c oxidase helps stabilize HIF-1α in hypoxic mammalian cells. Biochemical and biophysical research communications 420(4): 727-732.
• 2289 Bao, Q., et al. (2012). Mesenchymal stem cell-based tumor-targeted gene therapy in gastrointestinal cancer. Stem Cells Dev 21(13): 2355-2363.
• 2290 Barbosa, H., et al. (2012). New insights into the mechanisms of embryonic stem cell self-renewal under hypoxia: a multifactorial analysis approach. PLOS ONE 7(6)
• 2291 Benderro, G. F., et al. (2012). Decreased VEGF expression and microvascular density, but increased HIF-1 and 2α accumulation and EPO expression in chronic moderate hyperoxia in the mouse brain. Brain research 1471: 46-55
• 2292 Bendix, I., et al. (2012). Erythropoietin modulates autophagy signaling in the developing rat brain in an in vivo model of oxygen-toxicity. Int J Mol Sci 13(10): 12939-12951.
• 2293 Bendix, I., et al. (2012). Hyperoxia changes the balance of the thioredoxin/peroxiredoxin system in the neonatal rat brain. Brain Res 1484: 68-75.
• 2294 Boregowda, S. V. and D. G. Phinney (2012). Therapeutic applications of mesenchymal stem cells: current outlook. BioDrugs 26(4): 201-208.
• 2295 Boregowda, S. V., et al. (2012). Atmospheric oxygen inhibits growth and differentiation of marrow-derived mouse mesenchymal stem cells via a p53-dependent mechanism: implications for long-term culture expansion. Stem Cells 30(5): 975-987.
• 2296 Boroujerdi, A., et al. (2012). Chronic cerebral hypoxia promotes arteriogenic remodeling events that can be identified by reduced endoglin (CD105) expression and a switch in β1 integrins. Journal of Cerebral Blood Flow & Metabolism 32(9): 1820-1830
• 2297 Bourgeaux, V., et al. (2012). Efficacy of homologous inositol hexaphosphate-loaded red blood cells in sickle transgenic mice. Br J Haematol 157(3): 357-369.
• 2298 Bozyk, P. D., et al. (2012). Neonatal periostin knockout mice are protected from hyperoxia-induced alveolar simplification. PLOS ONE 7(2): e31336
• 2299 Brehmer, F., et al. (2012). Interaction of inflammation and hyperoxia in a rat model of neonatal white matter damage. PLOS ONE 7(11): e49023.
• 2300 Cahill, E., et al. (2012). The pathophysiological basis of chronic hypoxic pulmonary hypertension in the mouse: vasoconstrictor and structural mechanisms contribute equally. Exp Physiol 97(6): 796-806.
• 2301 Carreras, A., et al. (2012). Metabolic effects of intermittent hypoxia in mice: steady versus high-frequency applied hypoxia daily during the rest period. Am J Physiol Regul Integr Comp Physiol 303(7): R700-709.
• 2302 Chai, T. F., et al. (2012). A potential mechanism of metformin-mediated regulation of glucose homeostasis: inhibition of Thioredoxin-interacting protein (Txnip) gene expression. Cell Signal 24(8): 1700-1705.
• 2303 Charriaut-Marlangue, C., et al. (2012). Inhaled nitric oxide reduces brain damage by collateral recruitment in a neonatal stroke model. Stroke 43(11): 3078-3084.
• 2304 Chintala, H., et al. (2012). Connective tissue growth factor regulates retinal neovascularization through p53 protein-dependent transactivation of the matrix metalloproteinase (MMP)-2 gene. Journal of Biological Chemistry 287(48): 40570-40585
• 2305 Chiu, C. Z., et al. (2012). Use of atorvastatin to inhibit hypoxia‐induced myocardin expression. European journal of clinical investigation 42(5): 564-571
• 2306 Chiu, G. S., et al. (2012). Hypoxia/reoxygenation impairs memory formation via adenosine-dependent activation of caspase 1. J Neurosci 32(40): 13945-13955.
• 2307 Choi, J.-H., et al. (2012). Effects of hypoxia inducible factors-1α on autophagy and invasion of trophoblasts. Clinical and experimental reproductive medicine 39(2): 73-80
• 2308 Chou, C. W., et al. (2012). Tumor cycling hypoxia induces chemoresistance in glioblastoma multiforme by upregulating the expression and function of ABCB1. Neuro Oncol 14(10): 1227-1238.
• 2309 Chou, H. C., et al. (2012). Angiotensin II type 1 receptor antagonist attenuates lung fibrosis in hyperoxia-exposed newborn rats. J Pharmacol Exp Ther 340(1): 169-175.
• 2310 Christou, H., et al. (2012). Improved pulmonary vascular reactivity and decreased hypertrophic remodeling during nonhypercapnic acidosis in experimental pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 302(9): L875-890.
• 2311 Chui, T. Y., et al. (2012). Refractive Development in the “ROP Rat”. J Ophthalmol 2012: 956705.
• 2312 Cochemé, H. M., et al. (2012). Using the mitochondria-targeted ratiometric mass spectrometry probe MitoB to measure H2O2 in living Drosophila. Nature protocols 7(5): 946-958
• 2313 Contreras, M., et al. (2012). Hypercapnic acidosis attenuates ventilation-induced lung injury by a nuclear factor-κB–dependent mechanism. Critical care medicine 40(9): 2622-2630
• 2314 Cook, C. C., et al. (2012). Consumption of oxygen: a mitochondrial-generated progression signal of advanced cancer. Cell Death Dis 3(1): e258.
• 2315 Costa-Silva, J. H., et al. (2012). Chronic intermittent hypoxia alters glutamatergic control of sympathetic and respiratory activities in the commissural NTS of rats. Am J Physiol Regul Integr Comp Physiol 302(6): R785-793.
• 2316 Criswell, K., et al. (2012). Pregabalin Induces Hepatic Hypoxia and Increases Endothelial Cell Proliferation in is Mice which Attenuated by Dietary Vitamin E Supplementation. Toxicological Sciences: kfs148
• 2317 D’Souza, A., et al. (2012). Cytokines and Toll-like receptor signaling pathways in the terminal ileum of hypoxic/hyperoxic neonatal rats: benefits of probiotics supplementation. American journal of translational research 4(2): 187
• 2318 Dayyat, E. A., et al. (2012). Exogenous erythropoietin administration attenuates intermittent hypoxia-induced cognitive deficits in a murine model of sleep apnea. BMC Neurosci 13(1): 77.
• 2319 de Jesus Perez, V. A., et al. (2012). Loss of adenomatous poliposis coli-α3 integrin interaction promotes endothelial apoptosis in mice and humans. Circulation research 111(12): 1551-1564
• 2320 De Meyer, S. F., et al. (2012). Extracellular chromatin is an important mediator of ischemic stroke in mice. Arteriosclerosis, thrombosis, and vascular biology 32(8): 1884-1891
• 2321 DeNiro, M. and F. A. Al-Mohanna (2012). Zinc transporter 8 (ZnT8) expression is reduced by ischemic insults: a potential therapeutic target to prevent ischemic retinopathy. PLOS ONE 7(11): e50360
• 2322 Detwiler, D. A., et al. (2012). Polystyrene-coated micropallets for culture and separation of primary muscle cells. Anal Bioanal Chem 402(3): 1083-1091.
• 2323 Diaz, F., et al. (2012). Cells lacking Rieske iron-sulfur protein have a reactive oxygen species-associated decrease in respiratory complexes I and IV. Molecular and Cellular Biology 32(2): 415-429
• 2324 Dvoriantchikova, G., et al. (2012). Genetic ablation of Pannexin1 protects retinal neurons from ischemic injury. PLOS ONE 7(2): e31991.
• 2325 Dyugovskaya, L., et al. (2012). Bax/Mcl-1 balance affects neutrophil survival in intermittent hypoxia and obstructive sleep apnea: effects of p38MAPK and ERK1/2 signaling. J Transl Med 10: 211.
• 2326 El-Mousleh, T., et al. (2012). Exploring the potential of low doses carbon monoxide as therapy in pregnancy complications. Med Gas Res 2(1): 4
• 2327 Famulla, S., et al. (2012). Differentiation of human adipocytes at physiological oxygen levels results in increased adiponectin secretion and isoproterenol-stimulated lipolysis. Adipocyte 1(3): 132-181.
• 2328 Farrow, K. N., et al. (2012). Brief hyperoxia increases mitochondrial oxidation and increases phosphodiesterase 5 activity in fetal pulmonary artery smooth muscle cells. Antioxid Redox Signal 17(3): 460-470.
• 2329 Fenik, V. B., et al. (2012). Glucoregulatory consequences and cardiorespiratory parameters in rats exposed to chronic–intermittent hypoxia: effects of the duration of exposure and losartan. Frontiers in neurology 3
• 2330 Fernandez-Gonzalez, A., et al. (2012). Vasculoprotective effects of heme oxygenase-1 in a murine model of hyperoxia-induced bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol 302(8): L775-784.
• 2331 Fike, C. D., et al. (2012). Prolonged hypoxia augments L-citrulline transport by system A in the newborn piglet pulmonary circulation. Cardiovasc Res 95(3): 375-384.
• 2332Foda, H. and J. Patel (2012). Extracellular Matrix Metalloproteinase Inducer (emmprin) Upregulation By Hypoxia Partially Regulates Hypoxia-Inducible Factor-1 Alpha (hif-1α) Release In Human Lung Epithelial Cells. Am J Respir Crit Care Med 185: A2135
• 2333Foda, H. and J. Patel (2012). Hyperoxia Promotes Extracellular Matrix Metalloproteinase Inducer (emmprin) Upregulation In Airway Epithelial Cells. Am J Respir Crit Care Med 185: A2124
• 2334 Foldager, C. B., et al. (2012). Dermatan sulphate in methoxy polyethylene glycol-polylactide-co-glycolic acid scaffolds upregulates fibronectin gene expression but has no effect on in vivo osteochondral repair. International orthopaedics 36(7): 1507-1513.
• 2335 Fox, K., et al. (2012). Recent advances in research applications of nanophase hydroxyapatite. Chemphyschem 13(10): 2495-2506.
• 2336 Foxler, D. E., et al. (2012). The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity. NATURE CELL BIOLOGY 14(2): 201-208
• 2337 Fraker, C. A., et al. (2012). Optimization of perfluoro nano-scale emulsions: the importance of particle size for enhanced oxygen transfer in biomedical applications. Colloids Surf B Biointerfaces 98: 26-35.
• 2338 Frohlich, J. D., et al. (2012). Oxygen modulates the response of first-trimester trophoblasts to hyperglycemia. Am J Pathol 180(1): 153-164.
• 2339 Fu, Z. J., et al. (2012). Aldose Reductase Deficiency Reduced Vascular Changes in Neonatal Mouse Retina in Oxygen-Induced RetinopathyAR Deficiency Protects Retinal Vasculature in OIR. Investigative Ophthalmology & Visual Science 53(9): 5698-5712
• 2340 Gamboa, J. L. and F. H. Andrade (2012). Muscle endurance and mitochondrial function after chronic normobaric hypoxia: contrast of respiratory and limb muscles. Pflugers Arch 463(2): 327-338.
• 2341 Gattas-Asfura, K. M., et al. (2012). Perfluorinated alginate for cellular encapsulation. J Biomed Mater Res A 100(8): 1963-1971.
• 2342 Gerace, E., et al. (2012). Mild activation of poly (ADP‐ribose) polymerase (PARP) is neuroprotective in rat hippocampal slice models of ischemic tolerance. European Journal of Neuroscience 36(1): 1993-2005
• 2343 Gharib, S. A., et al. (2012). Intermittent hypoxia activates temporally coordinated transcriptional programs in visceral adipose tissue. J Mol Med (Berl) 90(4): 435-445.
• 2344 Gleixner, E., et al. (2012). Testes-specific hemoglobins in Drosophila evolved by a combination of sub- and neofunctionalization after gene duplication. BMC Evol Biol 12(1): 34.
• 2345 Gokey, T., et al. (2012). Conformational dynamics of threonine 195 and the S1 subsite in functional trypsin variants. J Mol Model 18(11): 4941-4954.
• 2346 Gold, B., et al. (2012). Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials. Proc Natl Acad Sci U S A 109(40): 16004-16011.
• 2347 Grinnell, K., et al. (2012). Heterogeneity in apoptotic responses of microvascular endothelial cells to oxidative stress. J Cell Physiol 227(5): 1899-1910.
• 2348 Gu, S., et al. (2012). Optical coherence tomography captures rapid hemodynamic responses to acute hypoxia in the cardiovascular system of early embryos. Dev Dyn 241(3): 534-544.
• 2349 Guo, J., et al. (2012). 17β-Estradiol prevents cell death and mitochondrial dysfunction by an estrogen receptor-dependent mechanism in astrocytes after oxygen–glucose deprivation/reperfusion. Free Radical Biology and Medicine 52(11): 2151-2160
• 2350 Gyabaah, K., et al. (2012). Controlled regulation of erythropoietin by primary cultured renal cells for renal failure induced anemia. J Urol 188(5): 2000-2006.
• 2351 Haddad, D., et al. (2012). A novel genetically modified oncolytic vaccinia virus in experimental models is effective against a wide range of human cancers. Ann Surg Oncol 19 Suppl 3: S665-674.
• 2352 Haga, C. L. and D. G. Phinney (2012). MicroRNAs in the imprinted DLK1-DIO3 region repress the epithelial-to-mesenchymal transition by targeting the TWIST1 protein signaling network. J Biol Chem 287(51): 42695-42707.
• 2353 Hamidi, T., et al. (2012). Nupr1-aurora kinase A pathway provides protection against metabolic stress-mediated autophagic-associated cell death. Clin Cancer Res 18(19): 5234-5246.
• 2354 Hammoud, M., et al. (2012). Combination of low O2 concentration and mesenchymal stromal cells during culture of cord blood CD34+ cells improves the maintenance and proliferative capacity of hematopoietic stem cells. Journal of Cellular Physiology 227(6): 2750-2758
• 2355 Hansmann, G., et al. (2012). Mesenchymal stem cell-mediated reversal of bronchopulmonary dysplasia and associated pulmonary hypertension. Pulm Circ 2(2): 170-181.
• 2356 Heather, L. C., et al. (2012). Metabolic adaptation to chronic hypoxia in cardiac mitochondria. Basic Res Cardiol 107(3): 268.
• 2357 Heinrichsen, E. T. and G. G. Haddad (2012). Role of high-fat diet in stress response of Drosophila. PLOS ONE 7(8): e42587.
• 2358 Hildreth, R. L., et al. (2012). Viral mitochondria-localized inhibitor of apoptosis (UL37 exon 1 protein) does not protect human neural precursor cells from human cytomegalovirus-induced cell death. Journal of General Virology 93(Pt 11): 2436-2446
• 2359 Hofmann, N. A., et al. (2012). Oxygen sensing mesenchymal progenitors promote neo-vasculogenesis in a humanized mouse model in vivo. PLOS ONE 7(9): e44468.
• 2360 Hofstetter, C. P., et al. (2012). Protein phosphatase 2A mediates dormancy of glioblastoma multiforme-derived tumor stem-like cells during hypoxia. PLOS ONE 7(1): e30059.
• 2361 Hollenbeck, S. T., et al. (2012). Tissue engraftment of hypoxic-preconditioned adipose-derived stem cells improves flap viability. Wound Repair Regen 20(6): 872-878.
• 2362 Hosny, N. A., et al. (2012). Single photon counting fluorescence lifetime detection of pericellular oxygen concentrations. J Biomed Opt 17(1): 016007.
• 2363 Hsieh, C. H., et al. (2012). Imaging the impact of Nox4 in cycling hypoxia-mediated U87 glioblastoma invasion and infiltration. Mol Imaging Biol 14(4): 489-499.
• 2364 Hsieh, C. H., et al. (2012). NADPH oxidase subunit 4 mediates cycling hypoxia-promoted radiation resistance in glioblastoma multiforme. Free Radic Biol Med 53(4): 649-658.
• 2365 Ikejiri, A., et al. (2012). Dynamic regulation of Th17 differentiation by oxygen concentrations. Int Immunol 24(3): 137-146.
• 2366 Ji, K. and S. E. Tsirka (2012). Inflammation modulates expression of laminin in the central nervous system following ischemic injury. J Neuroinflammation 9(159): 159.
• 2367 Jing, D., et al. (2012). Oxygen tension plays a critical role in the hematopoietic microenvironment in vitro. Haematologica 97(3): 331-339.
• 2368 Johnson, P. L., et al. (2012). Activation of the orexin 1 receptor is a critical component of CO2-mediated anxiety and hypertension but not bradycardia. Neuropsychopharmacology 37(8): 1911-1922
• 2369KABAYAMA, J., et al. (2012). Effects of subconjunctival injection of anti-vascular endothelial growth factor antibody on oxygen-induced ischemic retinopathy in a neonatal rat model. The Showa University Journal of Medical Sciences 24(1): 11-19
• 2370 Kang, S. S., et al. (2012). Loss of neuron-astroglial interaction rapidly induces protective CNTF expression after stroke in mice. J Neurosci 32(27): 9277-9287.
• 2371 Karlenius, T. C., et al. (2012). Cycling hypoxia up-regulates thioredoxin levels in human MDA-MB-231 breast cancer cells. Biochem Biophys Res Commun 419(2): 350-355.
• 2372 Karoor, V., et al. (2012). Alveolar hypoxia promotes murine lung tumor growth through a VEGFR-2/EGFR-dependent mechanism. Cancer Prevention Research 5(8): 1061-1071
• 2373 Kaushal, N., et al. (2012). Human apolipoprotein E4 targeted replacement in mice reveals increased susceptibility to sleep disruption and intermittent hypoxia. Am J Physiol Regul Integr Comp Physiol 303(1): R19-29.
• 2374 Kempster, S. L., et al. (2012). Disruption of paraoxonase 3 impairs proliferation and antioxidant defenses in human A549 cells and causes embryonic lethality in mice. Am J Physiol Endocrinol Metab 302(1): E103-107.
• 2375 Kim, S. J., et al. (2012). Retinal proteome analysis in a mouse model of oxygen-induced retinopathy. J Proteome Res 11(11): 5186-5203.
• 2376 Kim, S. Y., et al. (2012). Bortezomib alleviates experimental pulmonary arterial hypertension. Am J Respir Cell Mol Biol 47(5): 698-708.
• 2377 King, T. L., et al. (2012). Hypoxia activates nucleus tractus solitarii neurons projecting to the paraventricular nucleus of the hypothalamus. Am J Physiol Regul Integr Comp Physiol 302(10): R1219-1232.
• 2378 Konsavage, W. M., et al. (2012). Hyperoxia-induced activation of the integrated stress response in the newborn rat lung. Am J Physiol Lung Cell Mol Physiol 302(1): L27-35.
• 2379 Koulnis, M., et al. (2012). Contrasting dynamic responses in vivo of the Bcl-xL and Bim erythropoietic survival pathways. Blood 119(5): 1228-1239.
• 2380 Krause, B. J., et al. (2012). Role of arginase-2 and eNOS in the differential vascular reactivity and hypoxia-induced endothelial response in umbilical arteries and veins. Placenta 33(5): 360-366.
• 2381 Lee, B. F., et al. (2012). Hypoxia imaging predicts success of hypoxia-induced cytosine deaminase/5-fluorocytosine gene therapy in a murine lung tumor model. Cancer Gene Ther 19(4): 255-262.
• 2382 Lee, P., et al. (2012). Severe microcytic anemia but increased erythropoiesis in mice lacking Hfe or Tfr2 and Tmprss6. Blood Cells Mol Dis 48(3): 173-178.
• 2383 Lehman, N. L., et al. (2012). Aurora A is differentially expressed in gliomas, is associated with patient survival in glioblastoma and is a potential chemotherapeutic target in gliomas. Cell Cycle 11(3): 489-502
• 2384 Leijten, J. C., et al. (2012). Hypoxia inhibits hypertrophic differentiation and endochondral ossification in explanted tibiae. PLOS ONE 7(11): e49896.
• 2385 Levin, V. A., et al. (2012). Protein and phosphoprotein levels in glioma and adenocarcinoma cell lines grown in normoxia and hypoxia in monolayer and three-dimensional cultures. Proteome Sci 10(1): 5.
• 2386 Li, J., et al. (2012). Down-regulation of MutS homolog 3 by hypoxia in human colorectal cancer. Biochim Biophys Acta 1823(4): 889-899.
• 2387 Li, J., et al. (2012). N-methyl-D-aspartate receptor subtype 3A promotes apoptosis in developing mouse brain exposed to hyperoxia. Neural Regen Res 7(4): 273-277.
• 2388 Li, L., et al. (2012). An angiogenic role for the α5β1 integrin in promoting endothelial cell proliferation during cerebral hypoxia. Experimental neurology 237(1): 46-54
• 2389 Li, X., et al. (2012). Epidermal growth factor-ferritin H-chain protein nanoparticles for tumor active targeting. Small 8(16): 2505-2514.
• 2390 Liang, D., et al. (2012). The hypoxic microenvironment upgrades stem-like properties of ovarian cancer cells. BMC cancer 12(1): 201.
• 2391 Liang, X. J., et al. (2012). Phosphomannopentaose sulfate (PI-88) suppresses angiogenesis by downregulating heparanase and vascular endothelial growth factor in an oxygen-induced retinal neovascularization animal model. Mol Vis 18: 1649-1657.
• 2392 Liang, X. L., et al. (2012). A comparing study of quantitative staining techniques for retinal neovascularization in a mouse model of oxygen-induced retinopathy. Int J Ophthalmol 5(1): 1-6.
• 2393 Liew, S. Y., et al. (2012). Hypoxia affects cellular responses to plant extracts. J Ethnopharmacol 144(2): 453-456.
• 2394 Lin, H. H., et al. (2012). Identification of an AAA ATPase VPS4B-dependent pathway that modulates epidermal growth factor receptor abundance and signaling during hypoxia. Molecular and Cellular Biology 32(6): 1124-1138
• 2395 Liu, Q., et al. (2012). Hypoxia-inducible factor regulates hepcidin via erythropoietin-induced erythropoiesis. J Clin Invest 122(12): 4635-4644.
• 2396 Locy, M. L., et al. (2012). Thioredoxin reductase inhibition elicits Nrf2-mediated responses in Clara cells: implications for oxidant-induced lung injury. Antioxid Redox Signal 17(10): 1407-1416.
• 2397 Lu, Q., et al. (2012). Increased NADPH oxidase-derived superoxide is involved in the neuronal cell death induced by hypoxia–ischemia in neonatal hippocampal slice cultures. Free Radical Biology and Medicine 53(5): 1139-1151
• 2398 Lv, C., et al. (2012). Blocking the Na+/H+ exchanger 1 with cariporide (HOE642) reduces the hypoxia-induced invasion of human tongue squamous cell carcinoma. Int J Oral Maxillofac Surg 41(10): 1206-1210.
• 2399 Maile, L. A., et al. (2012). Disruption of the association of integrin-associated protein (IAP) with tyrosine phosphatase non-receptor type substrate-1 (SHPS)-1 inhibits pathophysiological changes in retinal endothelial function in a rat model of diabetes. Diabetologia 55(3): 835-844.
• 2400 Mishra, S., et al. (2012). Poly(alkylene oxide) copolymers for nucleic acid delivery. Acc Chem Res 45(7): 1057-1066.
• 2401 Murugesan, N., et al. (2012). Brain regional angiogenic potential at the neurovascular unit during normal aging. Neurobiology of aging 33(5): 1004. e1001-1004. e1016
• 2402 Na, K. H., et al. (2012). Dynamic alterations in integrin α4 expression by hypoxia are involved in trophoblast invasion during early implantation. Journal of cellular biochemistry 113(2): 685-694
• 2403 Nair, D., et al. (2012). Adverse cognitive effects of high-fat diet in a murine model of sleep apnea are mediated by NADPH oxidase activity. Neuroscience 227: 361-369.
• 2404 Nakamura, S., et al. (2012). Candesartan, an angiotensin II type 1 receptor antagonist, inhibits pathological retinal neovascularization by downregulating VEGF receptor-2 expression. Eur J Pharmacol 685(1-3): 8-14.
• 2405 Nakamura, S., et al. (2012). Morphological and functional changes in the retina after chronic oxygen-induced retinopathy. PLOS ONE 7(2): e32167.
• 2406Narwal, S., et al. (2012). Behavior & pharmacological animal models for the evaluation of learning & memory condition. Indo Global J Pharm Sci 2(2): 121-129
• 2407 O’Bryhim, B. E., et al. (2012). The genetic control of avascular area in mouse oxygen-induced retinopathy. Molecular vision 18: 377
• 2408 Ogle, M. E., et al. (2012). Inhibition of prolyl hydroxylases by dimethyloxaloylglycine after stroke reduces ischemic brain injury and requires hypoxia inducible factor-1α. Neurobiology of disease 45(2): 733-742
• 2409 Olave, N., et al. (2012). Transforming growth factor-beta regulates endothelin-1 signaling in the newborn mouse lung during hypoxia exposure. Am J Physiol Lung Cell Mol Physiol 302(9): L857-865.
• 2410 Oliner, J. D., et al. (2012). AMG 386, a Selective Angiopoietin 1/2-Neutralizing Peptibody, Inhibits Angiogenesis in Models of Ocular Neovascular DiseasesEffect of AMG 386 on Ocular Neovascularization. Investigative Ophthalmology & Visual Science 53(4): 2170-2180
• 2411 Parikh, V. N., et al. (2012). MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: results of a network bioinformatics approach. Circulation 125(12): 1520-1532.
• 2412 Park, E. C., et al. (2012). Hypoxia regulates glutamate receptor trafficking through an HIF‐independent mechanism. The EMBO journal 31(6): 1379-1393.
• 2413 Peng, G., et al. (2012). Sustained therapeutic hypercapnia attenuates pulmonary arterial Rho-kinase activity and ameliorates chronic hypoxic pulmonary hypertension in juvenile rats. Am J Physiol Heart Circ Physiol 302(12): H2599-2611.
• 2414 Perveen, S., et al. (2012). Role of EC-SOD overexpression in preserving pulmonary angiogenesis inhibited by oxidative stress. PLOS ONE 7(12): e51945.
• 2415 Phinney, D. G. (2012). Functional heterogeneity of mesenchymal stem cells: implications for cell therapy. J Cell Biochem 113(9): 2806-2812.
• 2416 Piao, L., et al. (2012). GRK2-mediated inhibition of adrenergic and dopaminergic signaling in right ventricular hypertrophy: therapeutic implications in pulmonary hypertension. Circulation 126(24): 2859-2869.
• 2417 Popova, A. P., et al. (2012). Glycogen synthase kinase-3beta/beta-catenin signaling regulates neonatal lung mesenchymal stromal cell myofibroblastic differentiation. Am J Physiol Lung Cell Mol Physiol 303(5): L439-448.
• 2418 Porzionato, A., et al. (2012). Fluoxetine may worsen hyperoxia-induced lung damage in neonatal rats. Histology and histopathology 27(10): 1599
• 2419 Prows, D. R., et al. (2012). Synchronizing allelic effects of opposing quantitative trait loci confirmed a major epistatic interaction affecting acute lung injury survival in mice. PLOS ONE 7(5): e38177.
• 2420 Rasmussen, J. G., et al. (2012). Activation of protease-activated receptor 2 induces VEGF independently of HIF-1. PLOS ONE 7(9): e46087.
• 2421 Ren, M. L., et al. (2012). Allogeneic adipose-derived stem cells with low immunogenicity constructing tissue-engineered bone for repairing bone defects in pigs. Cell Transplant 21(12): 2711-2721.
• 2422 Richter, S., et al. (2012). Expression and role in glycolysis of human ADP-dependent glucokinase. Mol Cell Biochem 364(1-2): 131-145.
• 2423Riis, S. E. (2012). Hypoxia and Trypsin enhance the Proangiogenic Proper-ties of human Adipose-derived Stem Cells. Thesis
• 2424 Rodriguez, E. S., et al. (2012). Biosafety evaluation of recombinant protein production in goat mammary gland using adenoviral vectors: preliminary study. Biotechnol J 7(8): 1049-1053.
• 2425 Sahu, D., et al. (2012). A potentially common peptide target in secreted heat shock protein-90α for hypoxia-inducible factor-1α–positive tumors. Molecular biology of the cell 23(4): 602-613
• 2426 Sakulterdkiat, T., et al. (2012). Curcumin resistance induced by hypoxia in HepG2 cells is mediated by multidrug-resistance-associated proteins. Anticancer research 32(12): 5337-5342
• 2427 Saller, M. M., et al. (2012). Increased stemness and migration of human mesenchymal stem cells in hypoxia is associated with altered integrin expression. Biochemical and biophysical research communications 423(2): 379-385
• 2428 Schrobback, K., et al. (2012). Effects of oxygen and culture system on in vitro propagation and redifferentiation of osteoarthritic human articular chondrocytes. Cell Tissue Res 347(3): 649-663.
• 2429 Schrobback, K., et al. (2012). Effects of oxygen on zonal marker expression in human articular chondrocytes. Tissue Eng Part A 18(9-10): 920-933.
• 2430 Sensebe, L., et al. (2012). Limited acquisition of chromosomal aberrations in human adult mesenchymal stromal cells. Cell Stem Cell 10(1): 9-10; author reply 10-11.
• 2431 Sewing, A. C., et al. (2012). Therapeutic hypercapnia prevents bleomycin-induced pulmonary hypertension in neonatal rats by limiting macrophage-derived tumor necrosis factor-alpha. Am J Physiol Lung Cell Mol Physiol 303(1): L75-87.
• 2432 Shyu, K. G., et al. (2012). Angiotensin II mediates urotensin II expression by hypoxia in cultured cardiac fibroblast. Eur J Clin Invest 42(1): 17-26.
• 2433 Signore, M., et al. (2012). Identity and ranking of colonic mesenchymal stromal cells. J Cell Physiol 227(9): 3291-3300.
• 2434 Sparrow, D. B., et al. (2012). A mechanism for gene-environment interaction in the etiology of congenital scoliosis. Cell 149(2): 295-306.
• 2435 Stapor, P. C. and W. L. Murfee (2012). Identification of class III β-tubulin as a marker of angiogenic perivascular cells. Microvascular research 83(2): 257-262
• 2436 Stettner, G. M., et al. (2012). Effect of chronic intermittent hypoxia on noradrenergic activation of hypoglossal motoneurons. J Appl Physiol (1985) 112(2): 305-312.
• 2437 Stevenson, T. J., et al. (2012). Hypoxia disruption of vertebrate CNS pathfinding through ephrinB2 Is rescued by magnesium. PLoS Genet 8(4): e1002638.
• 2438 Sun, H., et al. (2012). Chronic hypoxia-induced upregulation of Ca2+-activated Cl- channel in pulmonary arterial myocytes: a mechanism contributing to enhanced vasoreactivity. J Physiol 590(15): 3507-3521.
• 2439 Tao, J. D., et al. (2012). Histopathologic correlation with diffusion tensor imaging after chronic hypoxia in the immature ferret. Pediatr Res 71(2): 192-198.
• 2440 Tropea, K. A., et al. (2012). Bronchioalveolar stem cells increase after mesenchymal stromal cell treatment in a mouse model of bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol 302(9): L829-837.
• 2441 Tuomela, J., et al. (2012). Low TLR9 expression defines an aggressive subtype of triple-negative breast cancer. Breast Cancer Res Treat 135(2): 481-493.
• 2442 Tuteja, N., et al. (2012). Recent advances in development of marker-free transgenic plants: regulation and biosafety concern. J Biosci 37(1): 167-197.
• 2443 Urbani, L., et al. (2012). Hypoxia increases mouse satellite cell clone proliferation maintaining both in vitro and in vivo heterogeneity and myogenic potential. PLOS ONE 7(11): e49860.
• 2444 Usatyuk, P. V., et al. (2012). Novel role for non-muscle myosin light chain kinase (MLCK) in hyperoxia-induced recruitment of cytoskeletal proteins, NADPH oxidase activation, and reactive oxygen species generation in lung endothelium. J Biol Chem 287(12): 9360-9375.
• 2445 Vadivel, A., et al. (2012). Critical role of the axonal guidance cue EphrinB2 in lung growth, angiogenesis, and repair. Am J Respir Crit Care Med 185(5): 564-574.
• 2446 Vekich, J. A., et al. (2012). Protein disulfide isomerase-associated 6 is an ATF6-inducible ER stress response protein that protects cardiac myocytes from ischemia/reperfusion-mediated cell death. Journal of molecular and cellular cardiology 53(2): 259-267
• 2447 Verschuren, M. T., et al. (2012). The effect of hypoxia-induced intrauterine growth restriction on renal artery function. J Dev Orig Health Dis 3(5): 333-341.
• 2448 Wang, C. T., et al. (2012). Reduced neuronal expression of ribose-5-phosphate isomerase enhances tolerance to oxidative stress, extends lifespan, and attenuates polyglutamine toxicity in Drosophila. Aging cell 11(1): 93-103.
• 2449 Wang, H., et al. (2012). Activation of peroxisome proliferator-activated receptor gamma prolongs islet allograft survival. Cell Transplant 21(10): 2111-2118.
• 2450 Wang, H., et al. (2012). VEGF-mediated STAT3 activation inhibits retinal vascularization by down-regulating local erythropoietin expression. Am J Pathol 180(3): 1243-1253.
• 2451 Wang, S., et al. (2012). A polysaccharides MDG-1 augments survival in the ischemic heart by inducing S1P release and S1P1 expression. Int J Biol Macromol 50(3): 734-740.
• 2452 Waszak, P., et al. (2012). Preconditioning enhances the paracrine effect of mesenchymal stem cells in preventing oxygen-induced neonatal lung injury in rats. Stem Cells Dev 21(15): 2789-2797.
• 2453 Wei, L., et al. (2012). Transplantation of hypoxia preconditioned bone marrow mesenchymal stem cells enhances angiogenesis and neurogenesis after cerebral ischemia in rats. Neurobiol Dis 46(3): 635-645.
• 2454 Wong, C. M., et al. (2012). Iron chelation inhibits the development of pulmonary vascular remodeling. Free Radic Biol Med 53(9): 1738-1747.
• 2455 Xia, L., et al. (2012). Enhanced proliferation and functions of in vitro expanded human hair follicle outer root sheath cells by low oxygen tension culture. Tissue Eng Part C Methods 18(8): 603-613.
• 2456 Xiao, J., et al. (2012). Cellular FLICE-inhibitory protein protects against cardiac remodelling after myocardial infarction. Basic Res Cardiol 107(1): 239.
• 2457 Xiao, L., et al. (2012). Induction of gastrin expression in gastrointestinal cells by hypoxia or cobalt is independent of hypoxia-inducible factor (HIF). Endocrinology 153(7): 3006-3016
• 2458 Xie, M., et al. (2012). SIRT1 regulates endothelial Notch signaling in lung cancer. PLOS ONE 7(9): e45331.
• 2459 Xin, H., et al. (2012). Association of the von Hippel–Lindau Protein with AUF1 and Posttranscriptional Regulation of VEGFA mRNA. Molecular Cancer Research 10(1): 108-120
• 2460 Yamaleyeva, L. M., et al. (2012). Cell therapy with human renal cell cultures containing erythropoietin-positive cells improves chronic kidney injury. Stem Cells Transl Med 1(5): 373-383.
• 2461 Yang, C., et al. (2012). Role of receptor-mediated endocytosis in the antiangiogenic effects of human T lymphoblastic cell-derived microparticles. Am J Physiol Regul Integr Comp Physiol 302(8): R941-949.
• 2462 Yang, S., et al. (2012). Defined xenogeneic-free and hypoxic environment provides superior conditions for long-term expansion of human adipose-derived stem cells. Tissue Eng Part C Methods 18(8): 593-602.
• 2463 York, J. M., et al. (2012). Individually ventilated cages cause chronic low-grade hypoxia impacting mice hematologically and behaviorally. Brain Behav Immun 26(6): 951-958.
• 2464 Yuen, B., et al. (2012). Mice expressing T4826I-RYR1 are viable but exhibit sex- and genotype-dependent susceptibility to malignant hyperthermia and muscle damage. FASEB J 26(3): 1311-1322.
• 2465 Yung, H. W., et al. (2012). Evidence of endoplasmic reticulum stress and protein synthesis inhibition in the placenta of non-native women at high altitude. The FASEB Journal 26(5): 1970-1981.
• 2466 Zara, S., et al. (2012). pPKCα mediated-HIF-1α activation related to the morphological modifications occurring in neonatal myocardial tissue in response to severe and mild hyperoxia. European journal of histochemistry: EJH 56(1)
• 2467 Zeng, X., et al. (2012). Protective effect of apelin on cultured rat bone marrow mesenchymal stem cells against apoptosis. Stem Cell Res 8(3): 357-367.
• 2468 Zhou, J., et al. (2012). Activation of peroxisome proliferator-activated receptor α (PPARα) suppresses hypoxia-inducible factor-1α (HIF-1α) signaling in cancer cells. Journal of Biological Chemistry 287(42): 35161-35169.
• 2469 Ziemińska, E., et al. (2012). Synergistic neurotoxicity of oxygen-glucose deprivation and tetrabromobisphenol A in vitro: role of oxidative stress. Pharmacological Reports 64(5): 1166-1178
• 2470Agaltsov, M., et al. (2011). SLEEP BREATHING DISORDERS AT PATIENTSWITH ACROMEGALY. Sleep Medicine 12: S9-S10
• 2471 Alphonse, R. S., et al. (2011). Activation of Akt protects alveoli from neonatal oxygen-induced lung injury. Am J Respir Cell Mol Biol 44(2): 146-154.
• 2472Arias, L., et al. (2011). Combining erythropoeitin and bone marrow stromal cell therapy after stroke. Translational Neuroscience 2(1): 6-12
• 2473 Azad, P., et al. (2011). Distinct role of Hsp70 in Drosophila hemocytes during severe hypoxia. Free Radic Biol Med 51(2): 530-538.
• 2474 Azadzoi, K. M., et al. (2011). Human bladder smooth muscle cell damage in disturbed oxygen tension. Urology 78(4): 967 e969-915.
• 2475 Bambrick, L., et al. (2011). In vitro cell culture pO2 is significantly different from incubator pO2. Biotechnology progress 27(4): 1185-1189.
• 2476 Barsoum, I. B., et al. (2011). Glyceryl trinitrate inhibits hypoxia-induced release of soluble fms-like tyrosine kinase-1 and endoglin from placental tissues. Am J Pathol 178(6): 2888-2896.
• 2477 Barsoum, I. B., et al. (2011). Hypoxia induces escape from innate immunity in cancer cells via increased expression of ADAM10: role of nitric oxide. Cancer Res 71(24): 7433-7441.
• 2478 Bertrand, Y., et al. (2011). Influence of glioma tumour microenvironment on the transport of ANG1005 via low-density lipoprotein receptor-related protein 1. Br J Cancer 105(11): 1697-1707.
• 2479 Briva, A., et al. (2011). Adenosine triphosphate–dependent calcium signaling during ventilator-induced lung injury is amplified by hypercapnia. Experimental lung research 37(8): 471-481
• 2480 Budinger, G. S., et al. (2011). Epithelial cell death is an important contributor to oxidant-mediated acute lung injury. American journal of respiratory and critical care medicine 183(8): 1043-1054
• 2481 Burr, D. B., et al. (2011). Treatment with connexin 46 siRNA suppresses the growth of human Y79 retinoblastoma cell xenografts in vivo. Exp Eye Res 92(4): 251-259.
• 2482 Burridge, P. W., et al. (2011). A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability. PLOS ONE 6(4): e18293.
• 2483 Cai, J., et al. (2011). A neonatal mouse model of intermittent hypoxia associated with features of apnea in premature infants. Respir Physiol Neurobiol 178(2): 210-217.
• 2484 Carreau, A., et al. (2011). Nitric oxide modulates the expression of endothelial cell adhesion molecules involved in angiogenesis and leukocyte recruitment. Exp Cell Res 317(1): 29-41.
• 2485 Cengiz, P., et al. (2011). Chronic neurological deficits in mice after perinatal hypoxia and ischemia correlate with hemispheric tissue loss and white matter injury detected by MRI. Dev Neurosci 33(3-4): 270-279.
• 2486 Cengiz, P., et al. (2011). Inhibition of Na+/H+ exchanger isoform 1 is neuroprotective in neonatal hypoxic ischemic brain injury. Antioxidants & redox signaling 14(10): 1803-1813
• 2487 Chai, T. F., et al. (2011). Hypoxia-inducible factor independent down-regulation of thioredoxin-interacting protein in hypoxia. FEBS Lett 585(3): 492-498.
• 2488 Chen, C. Y., et al. (2011). Baculovirus as a gene delivery vector: recent understandings of molecular alterations in transduced cells and latest applications. Biotechnol Adv 29(6): 618-631.
• 2489 Choudhary, G., et al. (2011). Bosentan attenuates right ventricular hypertrophy and fibrosis in normobaric hypoxia model of pulmonary hypertension. J Heart Lung Transplant 30(7): 827-833.
• 2490 Crnkovic, S., et al. (2011). Origin of neomuscularized vessels in mice exposed to chronic hypoxia. Respir Physiol Neurobiol 179(2-3): 342-345.
• 2491Delebecque, F., et al. (2011). ELEVATED PANCREATIC POLYPEPTIDE (PP) LEVELS IN OBSTRUCTIVE SLEEP APNEA. Sleep Medicine 12: S10
• 2492 DeNiro, M., et al. (2011). Inhibition of reactive gliosis prevents neovascular growth in the mouse model of oxygen-induced retinopathy. PLOS ONE 6(7): e22244.
• 2493 Dhaliwal, C. A., et al. (2011). Early retinal blood vessel growth in normal and growth restricted rat pups raised in oxygen and room air. Br J Ophthalmol 95(11): 1592-1596.
• 2494 Dyugovskaya, L., et al. (2011). Molecular Pathways of Spontaneous and TNF-α–Mediated Neutrophil Apoptosis under Intermittent Hypoxia. American Journal of Respiratory Cell and Molecular Biology 45(1): 154-162
• 2495 Ferrero, E., et al. (2011). CELLFOODTM IMPROVES RESPIRATORY METABOLISM OF ENDOTHELIAL CELLS AND INHIBITS HYPOXIA-INDUCED RECTIVE OXYGEN SPECIES (ROS) GENERATION. Journal of Physiology and Pharmacology 62(3): 287-293
• 2496 Fink, T., et al. (2011). Isolation and expansion of adipose-derived stem cells for tissue engineering. Front Biosci (Elite Ed) 3: 256-263.
• 2497 Foldager, C. B., et al. (2011). Combined 3D and hypoxic culture improves cartilage-specific gene expression in human chondrocytes. Acta Orthop 82(2): 234-240.
• 2498 Foldbjerg, R., et al. (2011). Cytotoxicity and genotoxicity of silver nanoparticles in the human lung cancer cell line, A549. Arch Toxicol 85(7): 743-750.
• 2499 Fukushima, Y., et al. (2011). Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice. J Clin Invest 121(5): 1974-1985.
• 2500Fuller, R. J., et al. (2011). Improving cotton embryo culture by simulating in ovulo nutrient and hormone levels. In Vitro Cellular & Developmental Biology-Plant 47(3): 410-419
• 2501 Gamboa, J. L., et al. (2011). Chronic hypoxia increases insulin-stimulated glucose uptake in mouse soleus muscle. Am J Physiol Regul Integr Comp Physiol 300(1): R85-91.
• 2502 Garbayo, E., et al. (2011). Neuroprotective properties of marrow‐isolated adult multilineage‐inducible cells in rat hippocampus following global cerebral ischemia are enhanced when complexed to biomimetic microcarriers. Journal of neurochemistry 119(5): 972-988
• 2503 Gauster, M., et al. (2011). Fibulin-5 expression in the human placenta. Histochem Cell Biol 135(2): 203-213.
• 2504 Gharib, S. A., et al. (2011). Transcriptional landscape of bone marrow-derived very small embryonic-like stem cells during hypoxia. Respir Res 12: 63
• 2505 Grahl, N., et al. (2011). In vivo hypoxia and a fungal alcohol dehydrogenase influence the pathogenesis of invasive pulmonary aspergillosis. PLoS pathog 7(7): e1002145.
• 2506 Guitart, A., et al. (2011). Very low oxygen concentration (0.1%) reveals two FDCP-Mix cell subpopulations that differ by their cell cycling, differentiation and p27KIP1 expression. Cell Death & Differentiation 18(1): 174-182
• 2507Han, Q., et al. (2011). Role of heme oxygenase-1 in intermittent hypoxia-induced inflammation and oxidative stress in eAhy 926 endothelial cell line. Hong Kong Medical Journal 17(1, suppl. 1): 29-29
• 2508 Hartmann, J. S., et al. (2011). Expression of vascular endothelial growth factor and pigment epithelial-derived factor in a rat model of retinopathy of prematurity. Mol Vis 17: 1577-1587.
• 2509 Hasan, A., et al. (2011). The matricellular protein cysteine-rich protein 61 (CCN1/Cyr61) enhances physiological adaptation of retinal vessels and reduces pathological neovascularization associated with ischemic retinopathy. J Biol Chem 286(11): 9542-9554.
• 2510 Haschemi, A., et al. (2011). Carbon monoxide induced PPARgamma SUMOylation and UCP2 block inflammatory gene expression in macrophages. PLOS ONE 6(10): e26376.
• 2511 Hasegawa, T., et al. (2011). Antioxidant properties of pioglitazone limit nicotinamide adenine dinucleotide phosphate hydrogen oxidase and augment superoxide dismutase activity in cardiac allotransplantation. J Heart Lung Transplant 30(10): 1186-1196.
• 2512 Herr, K. J., et al. (2011). Stereotyped fetal brain disorganization is induced by hypoxia and requires lysophosphatidic acid receptor 1 (LPA1) signaling. Proceedings of the National Academy of Sciences 108(37): 15444-15449
• 2513 Hillery, C. A., et al. (2011). Transient receptor potential vanilloid 1 mediates pain in mice with severe sickle cell disease. Blood 118(12): 3376-3383.
• 2514 Hu, X., et al. (2011). Hypoxic preconditioning enhances bone marrow mesenchymal stem cell migration via Kv2.1 channel and FAK activation. Am J Physiol Cell Physiol 301(2): C362-372.
• 2515 Huang, B., et al. (2011). Hypoxia-inducible factor-1 drives annexin A2 system-mediated perivascular fibrin clearance in oxygen-induced retinopathy in mice. Blood 118(10): 2918-2929.
• 2516 Huh, J. W., et al. (2011). YC-1 attenuates hypoxia-induced pulmonary arterial hypertension in mice. Pulm Pharmacol Ther 24(6): 638-646.
• 2517Husain, R. M. L., et al. (2011). Genomic assessment of a multikinase inhibitor. Eur Respir J 37(6): 1303-1305
• 2518 Johnson, A. S., et al. (2011). Quantitative assessment of islets of Langerhans encapsulated in alginate. Tissue Eng Part C Methods 17(4): 435-449.
• 2519 Johnson, P. L., et al. (2011). Induction of c-Fos in ‘panic/defence’-related brain circuits following brief hypercarbic gas exposure. J Psychopharmacol 25(1): 26-36.
• 2520 Julien, C. A., et al. (2011). Alteration of carotid body chemoreflexes after neonatal intermittent hypoxia and caffeine treatment in rat pups. Respir Physiol Neurobiol 177(3): 301-312.
• 2521 Kang, B.-Y., et al. (2011). The PPARγ ligand rosiglitazone attenuates hypoxia-induced endothelin signaling in vitro and in vivo. American Journal of Physiology-Lung Cellular and Molecular Physiology 301(6): L881-L891
• 2522 Karlenius, T. C., et al. (2011). The selenium content of cell culture serum influences redox-regulated gene expression. Biotechniques 50(5): 295-301.
• 2523 Kasi, V., et al. (2011). Zinc pyrithione salvages reperfusion injury by inhibiting NADPH oxidase activation in cardiomyocytes. Biochem Biophys Res Commun 410(2): 270-275.
• 2524 Kataoka, K., et al. (2011). The roles of vitreal macrophages and circulating leukocytes in retinal neovascularization. Invest Ophthalmol Vis Sci 52(3): 1431-1438.
• 2525 Kelly, T. J., et al. (2011). A hypoxia-induced positive feedback loop promotes hypoxia-inducible factor 1α stability through miR-210 suppression of glycerol-3-phosphate dehydrogenase 1-like. Molecular and Cellular Biology 31(13): 2696-2706
• 2526 Khatibi, N. H., et al. (2011). Endothelin receptor-A (ETa) inhibition fails to improve neonatal hypoxic-ischemic brain injury in rats. Acta Neurochir Suppl 111: 207-212.
• 2527 Kim, I., et al. (2011). Reference gene validation for qPCR in rat carotid body during postnatal development. BMC Res Notes 4(1): 440.
• 2528 Kim, Y., et al. (2011). Suppression of CFTR-mediated Cl secretion of airway epithelium in vitamin C-deficient mice. J Korean Med Sci 26(3): 317-324.
• 2529 Kondrikov, D., et al. (2011). Reactive oxygen species-dependent RhoA activation mediates collagen synthesis in hyperoxic lung fibrosis. Free Radic Biol Med 50(11): 1689-1698.
• 2530 Lai, A. Y., et al. (2011). Neonatal rat microglia derived from different brain regions have distinct activation responses. Neuron glia biology 7(01): 5-16
• 2531 Lan, W. C., et al. (2011). Sex-specific cognitive deficits and regional brain volume loss in mice exposed to chronic, sublethal hypoxia. Pediatr Res 70(1): 15-20.
• 2532 Landucci, E., et al. (2011). CB1 receptors and post-ischemic brain damage: studies on the toxic and neuroprotective effects of cannabinoids in rat organotypic hippocampal slices. Neuropharmacology 60(4): 674-682.
• 2533Larsen, B. F., et al. (2011). The Effect of Hypoxia and Trypsin on the Wound Healing Properties of Adipose-Derived Stem Cells. Thesis
• 2534 Le Moan, N., et al. (2011). Oxygen-dependent cleavage of the p75 neurotrophin receptor triggers stabilization of HIF-1α. Molecular cell 44(3): 476-490
• 2535 Lee, D.-C., et al. (2011). miR-210 targets iron-sulfur cluster scaffold homologue in human trophoblast cell lines: siderosis of interstitial trophoblasts as a novel pathology of preterm preeclampsia and small-for-gestational-age pregnancies. The American Journal of Pathology 179(2): 590-602
• 2536 Lee, H.-S. and C.-K. Kim (2011). Cathepsin B is activated as an executive protease in fetal rat alveolar type II cells exposed to hyperoxia. Experimental & molecular medicine 43(4): 223-229
• 2537 Lee, K. H., et al. (2011). Targeting energy metabolic and oncogenic signaling pathways in triple-negative breast cancer by a novel adenosine monophosphate-activated protein kinase (AMPK) activator. J Biol Chem 286(45): 39247-39258.
• 2538 Lehwald, N., et al. (2011). Wnt–β-catenin signaling protects against hepatic ischemia and reperfusion injury in mice. Gastroenterology 141(2): 707-718. e705.
• 2539 Leucker, T. M., et al. (2011). Endothelial–cardiomyocyte crosstalk enhances pharmacological cardioprotection. Journal of molecular and cellular cardiology 51(5): 803-811
• 2540 Li, D., et al. (2011). Adaptation to moderate hypoxia protects cortical neurons against ischemia–reperfusion injury and excitotoxicity independently of HIF-1α. Experimental neurology 230(2): 302-310
• 2541Li, G., et al. (2011). Melatonin protects mice with intermittent hypoxia from oxidative stress‐induced pancreatic injury. Sleep and Biological Rhythms 9(2): 78-85
• 2542 Li, R. C., et al. (2011). Exogenous growth hormone attenuates cognitive deficits induced by intermittent hypoxia in rats. Neuroscience 196: 237-250.
• 2543 Li, R. C., et al. (2011). Leukotriene B4 receptor-1 mediates intermittent hypoxia-induced atherogenesis. Am J Respir Crit Care Med 184(1): 124-131.
• 2544 Lin, C. D., et al. (2011). Transient ischemia/hypoxia enhances gentamicin ototoxicity via caspase-dependent cell death pathway. Lab Invest 91(7): 1092-1106.
• 2545 Lopez-Iglesias, P., et al. (2011). Short and long term fate of human AMSC subcutaneously injected in mice. World J Stem Cells 3(6): 53-62.
• 2546Lorcheim, K. (2011). Chlorine dioxide gas inactivation of beta-lactams. Appl Biosaf 16: 34-43
• 2547 Loron, G., et al. (2011). Ciprofloxacin prevents myelination delay in neonatal rats subjected to E. coli sepsis. Ann Neurol 69(2): 341-351.
• 2548 Lu, Q., et al. (2011). Increased p38 mitogen‐activated protein kinase signaling is involved in the oxidative stress associated with oxygen and glucose deprivation in neonatal hippocampal slice cultures. European Journal of Neuroscience 34(7): 1093-1101
• 2549 Luo, K., et al. (2011). Gadolinium-labeled peptide dendrimers with controlled structures as potential magnetic resonance imaging contrast agents. Biomaterials 32(31): 7951-7960.
• 2550 Luo, Y., et al. (2011). Differential expression of claudins in retinas during normal development and the angiogenesis of oxygen-induced retinopathy. Invest Ophthalmol Vis Sci 52(10): 7556-7564.
• 2551 Luwor, R. B., et al. (2011). Constitutively active Harvey Ras confers resistance to epidermal growth factor receptor–targeted therapy with cetuximab and gefitinib. Cancer letters 306(1): 85-91
• 2552 Ma, Y., et al. (2011). Prostate cancer cell lines under hypoxia exhibit greater stem-like properties. PLOS ONE 6(12): e29170.
• 2553Mak, J. C., et al. (2011). Effect of intermittent hypoxia on the expression of fatty acid binding proteins in human adipocytes and macrophages. European Respiratory Journal 38(Suppl 55): p3049
• 2554 Manalo, D. J., et al. (2011). Inactivation of prolyl hydroxylase domain (PHD) protein by epigallocatechin (EGCG) stabilizes hypoxia-inducible factor (HIF-1α) and induces hepcidin (Hamp) in rat kidney. Biochemical and biophysical research communications 416(3): 421-426
• 2555 McAneney, J., et al. (2011). Chronic hypoxia and chronic hypercapnia differentially regulate an NMDA-sensitive component of the acute hypercapnic ventilatory response in the cane toad (Rhinella marina). J Comp Physiol B 181(6): 793-805.
• 2556 Medina, R. J., et al. (2011). Myeloid angiogenic cells act as alternative M2 macrophages and modulate angiogenesis through interleukin-8. Molecular Medicine 17(9-10): 1045
• 2557 Mivelaz, Y., et al. (2011). Neonatal oxygen exposure leads to increased aortic wall stiffness in adult rats: a Doppler ultrasound study. J Dev Orig Health Dis 2(3): 184-189.
• 2558 Mody, P., et al. (2011). Rats subjected to chronic-intermittent hypoxia have increased density of noradrenergic terminals in the trigeminal sensory and motor nuclei. Neuroscience Letters 505(2): 176-179
• 2559 Molkov, Y. I., et al. (2011). Intermittent hypoxia-induced sensitization of central chemoreceptors contributes to sympathetic nerve activity during late expiration in rats. J Neurophysiol 105(6): 3080-3091.
• 2560 Morton, J. S., et al. (2011). Flow-mediated vasodilation is impaired in adult rat offspring exposed to prenatal hypoxia. Journal of Applied Physiology 110(4): 1073-1082
• 2561 Nair, D., et al. (2011). Intermittent hypoxia-induced cognitive deficits are mediated by NADPH oxidase activity in a murine model of sleep apnea. PLOS ONE 6(5): e19847.
• 2562 Nakamura, S., et al. (2011). An Arylidene-Thiazolidinedione Derivative, GPU-4, without PPARγ Activation, Reduces Retinal Neovascularization. Current neurovascular research 8(1): 25-34
• 2563 Nakamura, S., et al. (2011). Tissue kallikrein inhibits retinal neovascularization via the cleavage of vascular endothelial growth factor-165. Arterioscler Thromb Vasc Biol 31(5): 1041-1048.
• 2564 Natoli, R., et al. (2011). Morphological, functional and gene expression analysis of the hyperoxic mouse retina. Exp Eye Res 92(4): 306-314.
• 2565 Pae, E. K., et al. (2011). Perinatal intermittent hypoxia alters gamma-aminobutyric acid: a receptor levels in rat cerebellum. Int J Dev Neurosci 29(8): 819-826.
• 2566 Paes, K. T., et al. (2011). Frizzled 4 is required for retinal angiogenesis and maintenance of the blood-retina barrier. Investigative Ophthalmology & Visual Science 52(9): 6452-6461
• 2567 Paley, E. L., et al. (2011). Hypoxia signature of splice forms of tryptophanyl-tRNA synthetase marks pancreatic cancer cells with distinct metastatic abilities. Pancreas 40(7): 1043-1056.
• 2568 Paprocka, M., et al. (2011). CD133 positive progenitor endothelial cell lines from human cord blood. Cytometry A 79(8): 594-602.
• 2569 Park, K. C., et al. (2011). Potential anti‐cancer activity of N‐hydroxy‐7‐(2‐naphthylthio) heptanomide (HNHA), a histone deacetylase inhibitor, against breast cancer both in vitro and in vivo. Cancer science 102(2): 343-350
• 2570 Park, K., et al. (2011). Overexpression of Pigment Epithelium–Derived Factor Inhibits Retinal Inflammation and Neovascularization. The American Journal of Pathology 178(2): 688-698
• 2571 Perdiguero, E. G., et al. (2011). Alteration of developmental and pathological retinal angiogenesis in angptl4-deficient mice. J Biol Chem 286(42): 36841-36851.
• 2572 Perry, J. C., et al. (2011). Differential sympathetic activation induced by intermittent hypoxia and sleep loss in rats: Action of angiotensin (1–7). Autonomic Neuroscience 160(1): 32-36
• 2573 Pierre, S. V., et al. (2011). Modulation of Na(+)-K(+)-ATPase cell surface abundance through structural determinants on the alpha1-subunit. Am J Physiol Cell Physiol 300(1): C42-48.
• 2574 Poitz, D. M., et al. (2011). OxLDL and macrophage survival: essential and oxygen-independent involvement of the Hif-pathway. Basic Res Cardiol 106(5): 761-772.
• 2575 Prieto, C., et al. (2011). Hypoxia-reduced nitric oxide synthase activity is partially explained by higher arginase-2 activity and cellular redistribution in human umbilical vein endothelium. Placenta 32(12): 932-940
• 2576 Proulx-Bonneau, S. and B. Annabi (2011). The primary cilium as a biomarker in the hypoxic adaptation of bone marrow-derived mesenchymal stromal cells: a role for the secreted frizzled-related proteins. Biomarker insights 6: 107
• 2577 Proulx-Bonneau, S., et al. (2011). A concerted HIF-1alpha/MT1-MMP signalling axis regulates the expression of the 3BP2 adaptor protein in hypoxic mesenchymal stromal cells. PLOS ONE 6(6): e21511.
• 2578 Rahnemai-Azar, A., et al. (2011). Human marrow-isolated adult multilineage-inducible (MIAMI) cells protect against peripheral vascular ischemia in a mouse model. Cytotherapy 13(2): 179-192.
• 2579 Ramanathan, L. and J. M. Siegel (2011). Sleep deprivation under sustained hypoxia protects against oxidative stress. Free Radic Biol Med 51(10): 1842-1848.
• 2580 Rao, A. K., et al. (2011). 17β-Estradiol-mediated increase in Cu/Zn superoxide dismutase expression in the brain: a mechanism to protect neurons from ischemia. The Journal of steroid biochemistry and molecular biology 127(3): 382-389
• 2581 Rasmussen, J. G., et al. (2011). Prolonged hypoxic culture and trypsinization increase the pro-angiogenic potential of human adipose tissue-derived stem cells. Cytotherapy 13(3): 318-328.
• 2582 Raval, A. P., et al. (2011). Nicotine and estrogen synergistically exacerbate cerebral ischemic injury. Neuroscience 181: 216-225.
• 2583 Rennel, E. S., et al. (2011). A human neutralizing antibody specific to Ang-2 inhibits ocular angiogenesis. Microcirculation 18(7): 598-607.
• 2584 Rink, C., et al. (2011). Oxygen-inducible glutamate oxaloacetate transaminase as protective switch transforming neurotoxic glutamate to metabolic fuel during acute ischemic stroke. Antioxidants & redox signaling 14(10): 1777-1785
• 2585 Schmitz, T., et al. (2011). Cellular changes underlying hyperoxia-induced delay of white matter development. J Neurosci 31(11): 4327-4344.
• 2586 Shinohara, K., et al. (2011). Stromal cell-derived factor-1 and monocyte chemotactic protein-3 improve recruitment of osteogenic cells into sites of musculoskeletal repair. J Orthop Res 29(7): 1064-1069.
• 2587 Silva, A. Q. and A. M. Schreihofer (2011). Altered sympathetic reflexes and vascular reactivity in rats after exposure to chronic intermittent hypoxia. J Physiol 589(Pt 6): 1463-1476.
• 2588 Singh, D. K., et al. (2011). Hypoxia modulates the expression of leucine zipper-positive MYPT1 and its interaction with protein kinase G and Rho kinases in pulmonary arterial smooth muscle cells. Pulm Circ 1(4): 487-498.
• 2589 Skandalis, D. A., et al. (2011). Responses of Drosophila melanogaster to atypical oxygen atmospheres. J Insect Physiol 57(4): 444-451.
• 2590 Stewart, G. D., et al. (2011). DNA strand breaks and hypoxia response inhibition mediate the radiosensitisation effect of nitric oxide donors on prostate cancer under varying oxygen conditions. Biochem Pharmacol 81(2): 203-210.
• 2591 Sutendra, G., et al. (2011). The role of Nogo and the mitochondria–endoplasmic reticulum unit in pulmonary hypertension. Science translational medicine 3(88): 88ra55-88ra55.
• 2592 Talavera-Adame, D., et al. (2011). Characterization of microvascular endothelial cells isolated from the dermis of adult mouse tails. Microvasc Res 82(2): 97-104.
• 2593 Taylor, A. C., et al. (2011). Attenuation of ephrinB2 reverse signaling decreases vascularized area and preretinal vascular tuft formation in the murine model of oxygen-induced retinopathy. Investigative Ophthalmology & Visual Science 53(9): 5462-5470
• 2594Telerman, A., et al. (2011). Platelets/neutrophils Interactions In Obstructive Sleep Apnea And Intermittent Hypoxia In Vitro. Am J Respir Crit Care Med 183: A5347
• 2595 Tottey, S., et al. (2011). Extracellular matrix degradation products and low-oxygen conditions enhance the regenerative potential of perivascular stem cells. Tissue Eng Part A 17(1-2): 37-44.
• 2596 Valapala, M., et al. (2011). A competitive hexapeptide inhibitor of annexin A2 prevents hypoxia-induced angiogenic events. J Cell Sci 124(Pt 9): 1453-1464.
• 2597 Veschini, L., et al. (2011). The vasostatin-1 fragment of chromogranin A preserves a quiescent phenotype in hypoxia-driven endothelial cells and regulates tumor neovascularization. FASEB J 25(11): 3906-3914.
• 2598 Viswanath, K., et al. (2011). Cardioprotective effect of zinc requires ErbB2 and Akt during hypoxia/reoxygenation. Biometals 24(1): 171-180.
• 2599 Vlachantoni, D., et al. (2011). Evidence of severe mitochondrial oxidative stress and a protective effect of low oxygen in mouse models of inherited photoreceptor degeneration. Hum Mol Genet 20(2): 322-335.
• 2600 Vohwinkel, C. U., et al. (2011). Elevated CO2 levels cause mitochondrial dysfunction and impair cell proliferation. Journal of Biological Chemistry 286(43): 37067-37076
• 2601 Wang, D., et al. (2011). p21 WAF1 and hypoxia/reoxygenation-induced premature senescence of H9c2 cardiomyocytes. Folia Histochem Cytobiol 49(3): 445-451.
• 2602 Wang, S., et al. (2011). Bim is responsible for the inherent sensitivity of the developing retinal vasculature to hyperoxia. Developmental biology 349(2): 296-309
• 2603 Wang, Y., et al. (2011). Monocarboxylate transporter 2 and stroke severity in a rodent model of sleep apnea. J Neurosci 31(28): 10241-10248.
• 2604 Wohlkoenig, C., et al. (2011). Hypoxia-induced cisplatin resistance is reversible and growth rate independent in lung cancer cells. Cancer letters 308(2): 134-143.
• 2605 Wu, Y., et al. (2011). North American ginseng protects the heart from ischemia and reperfusion injury via upregulation of endothelial nitric oxide synthase. Pharmacol Res 64(3): 195-202.
• 2606 Xie, L. and J. F. Collins (2011). Transcriptional regulation of the Menkes copper ATPase (Atp7a) gene by hypoxia-inducible factor (HIF2{alpha}) in intestinal epithelial cells. Am J Physiol Cell Physiol 300(6): C1298-1305.
• 2607 Yan, T., et al. (2011). Neuronal markers are expressed in human gliomas and NSE knockdown sensitizes glioblastoma cells to radiotherapy and temozolomide. BMC cancer 11(1): 524.
• 2608 Yang, G., et al. (2011). Silencing hyperoxia-induced C/EBPα in neonatal mice improves lung architecture via enhanced proliferation of alveolar epithelial cells. American Journal of Physiology-Lung Cellular and Molecular Physiology 301(2): L187-L196
• 2609Yeung, S., et al. (2011). Intermittent Hypoxia Enhances Inflammation And Oxidative Stress In Eahy 926 Endothelial Cells Via Suppression Of Ho-1 Expression. Am J Respir Crit Care Med 183: A2475
• 2610 Zaiman, A. L., et al. (2011). A critical role for the protein apoptosis repressor with caspase recruitment domain in hypoxia-induced pulmonary hypertension. Circulation 124(23): 2533-2542.
• 2611 Zenclussen, M. L., et al. (2011). Haem oxygenase-1 dictates intrauterine fetal survival in mice via carbon monoxide. J Pathol 225(2): 293-304.
• 2612 Zhang, Y. F., et al. (2011). A comprehensive biological evaluation of ceramic nanoparticles as wear debris. Nanomedicine 7(6): 975-982.
• 2613 Zhou, H. Y., et al. (2011). Improving the antibacterial property of porcine small intestinal submucosa by nano-silver supplementation: a promising biological material to address the need for contaminated defect repair. Ann Surg 253(5): 1033-1041.
• 2614 Zoccal, D. B., et al. (2011). Chronic intermittent hypoxia augments sympatho-excitatory response to ATP but not to l-glutamate in the RVLM of rats. Autonomic Neuroscience 165(2): 156-162
• 2615 Zuloaga, K. L. and R. J. Gonzales (2011). Dihydrotestosterone attenuates hypoxia inducible factor-1α and cyclooxygenase-2 in cerebral arteries during hypoxia or hypoxia with glucose deprivation. American Journal of Physiology-Heart and Circulatory Physiology 301(5): H1882-H1890
• 2616 Aitken, K. J., et al. (2010). Mammalian target of rapamycin (mTOR) induces proliferation and de-differentiation responses to three coordinate pathophysiologic stimuli (mechanical strain, hypoxia, and extracellular matrix remodeling) in rat bladder smooth muscle. Am J Pathol 176(1): 304-319.
• 2617 Akula, J. D., et al. (2010). The anatomy of the rat eye with oxygen-induced retinopathy. Doc Ophthalmol 120(1): 41-50.
• 2618 Angelini, D. J., et al. (2010). Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELM alpha) recruits bone marrow-derived cells to the murine pulmonary vasculature. PLOS ONE 5(6): e11251.
• 2619 Aryee, D. N., et al. (2010). Hypoxia modulates EWS-FLI1 transcriptional signature and enhances the malignant properties of Ewing’s sarcoma cells in vitro. Cancer Res 70(10): 4015-4023.
• 2620 Badiwala, M. V., et al. (2010). Epidermal growth factor-like domain 7 suppresses intercellular adhesion molecule 1 expression in response to hypoxia/reoxygenation injury in human coronary artery endothelial cells. Circulation 122(11 Suppl): S156-161.
• 2621 Balasubramaniam, V., et al. (2010). Bone marrow-derived angiogenic cells restore lung alveolar and vascular structure after neonatal hyperoxia in infant mice. Am J Physiol Lung Cell Mol Physiol 298(3): L315-323.
• 2622 Banerjee, D., et al. (2010). A novel role of gap junction connexin46 protein to protect breast tumors from hypoxia. Int J Cancer 127(4): 839-848.
• 2623 Belik, J., et al. (2010). Pulmonary vascular and cardiac effects of peroxynitrite decomposition in newborn rats. Free Radic Biol Med 49(8): 1306-1314.
• 2624 Belloni, D., et al. (2010). Bortezomib induces autophagic death in proliferating human endothelial cells. Exp Cell Res 316(6): 1010-1018.
• 2625 Bucher, R. M., et al. (2010). The structure of the FnIII Tandem A77-A78 points to a periodically conserved architecture in the myosin-binding region of titin. J Mol Biol 401(5): 843-853.
• 2626 Budd, S. J. and M. E. Hartnett (2010). Increased angiogenic factors during avascular retina prior to neovascularization in ROP model. Archives of ophthalmology 128(5): 589
• 2627 Carvalho, C., et al. (2010). Chronic hypoxia potentiates age-related oxidative imbalance in brain vessels and synaptosomes. Curr Neurovasc Res 7(4): 288-300.
• 2628 Chachques, J. C. (2010). Development of bioartificial myocardium using stem cells and nanobiotechnology templates. Cardiology research and practice 2011
• 2629 Chacko, S. M., et al. (2010). Hypoxic preconditioning induces the expression of prosurvival and proangiogenic markers in mesenchymal stem cells. Am J Physiol Cell Physiol 299(6): C1562-1570.
• 2630 Chang, T.-T., et al. (2010). Hypoxia-mediated down-regulation of OCTN2 and PPARα expression in human placentas and in BeWo cells. Molecular pharmaceutics 8(1): 117-125.
• 2631 Chen, Q., et al. (2010). Adipose-derived stem cells modified genetically in vivo promote reconstruction of bone defects. Cytotherapy 12(6): 831-840.
• 2632 Chikaraishi, Y., et al. (2010). Angiostatic effects of Brazilian green propolis and its chemical constituents. Mol Nutr Food Res 54(4): 566-575.
• 2633 Chiu, C. Z., et al. (2010). Angiotensin II and the ERK pathway mediate the induction of myocardin by hypoxia in cultured rat neonatal cardiomyocytes. Clin Sci (Lond) 119(7): 273-282.
• 2634 Chua, Y. L., et al. (2010). Stabilization of hypoxia-inducible factor-1α protein in hypoxia occurs independently of mitochondrial reactive oxygen species production. Journal of Biological Chemistry 285(41): 31277-31284
• 2635 Corzo, C. A., et al. (2010). HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment. The Journal of experimental medicine 207(11): 2439-2453.
• 2636 Darby, C. M. and C. F. Nathan (2010). Killing of non-replicating Mycobacterium tuberculosis by 8-hydroxyquinoline. J Antimicrob Chemother 65(7): 1424-1427.
• 2637 Davis, N. F., et al. (2010). Xenogenic extracellular matrices as potential biomaterials for interposition grafting in urological surgery. J Urol 184(6): 2246-2253.
• 2638 DeNiro, M., et al. (2010). Pleiotropic effects of YC-1 selectively inhibit pathological retinal neovascularization and promote physiological revascularization in a mouse model of oxygen-induced retinopathy. Mol Pharmacol 77(3): 348-367.
• 2639 Dos Santos, F., et al. (2010). Ex vivo expansion of human mesenchymal stem cells: a more effective cell proliferation kinetics and metabolism under hypoxia. J Cell Physiol 223(1): 27-35.
• 2640 Douglas, R. M., et al. (2010). Neuronal death during combined intermittent hypoxia/hypercapnia is due to mitochondrial dysfunction. American Journal of Physiology-Cell Physiology 298(6): C1594-C1602
• 2641 Dyugovskaya, L. and A. Polyakov (2010). Neutrophil apoptosis and hypoxia. International Journal of Physiology and Pathophysiology 1(4)
• 2642 Farrell, M. R., et al. (2010). Thioredoxin-interacting protein inhibits hypoxia-inducible factor transcriptional activity. Free Radic Biol Med 49(9): 1361-1367.
• 2643 Farrow, K. N., et al. (2010). Mitochondrial oxidant stress increases PDE5 activity in persistent pulmonary hypertension of the newborn. Respir Physiol Neurobiol 174(3): 272-281.
• 2644 Fernandes, T. G., et al. (2010). Different stages of pluripotency determine distinct patterns of proliferation, metabolism, and lineage commitment of embryonic stem cells under hypoxia. Stem Cell Res 5(1): 76-89.
• 2645 Finney, M. R., et al. (2010). Umbilical cord blood-selected CD133(+) cells exhibit vasculogenic functionality in vitro and in vivo. Cytotherapy 12(1): 67-78.
• 2646Fung, T., et al. (2010). Functional characterisation of a novel nucleoporin gene NUP98 in zebrafish embryo. Hong Kong Medical Journal 16(suppl. 1): 21-21
• 2647 Gary-Bobo, G., et al. (2010). Effects of HIV protease inhibitors on progression of monocrotaline-and hypoxia-induced pulmonary hypertension in rats. Circulation 122(19): 1937-1947
• 2648 Gauster, M., et al. (2010). Caspases rather than cal