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• 1 Geng, H., et al. (2022). miR-431-5p regulates apoptosis of cardiomyocytes after acute myocardial infarction via targeting selenoprotein T. Physiol Res.
• 2 He, Y., et al. (2022). Pachymic Acid Ameliorates Pulmonary Hypertension by Regulating Nrf2-Keap1-ARE Pathway. Curr Med Sci 42(1): 56-67.
• 3 Hou, Y., et al. (2022). Mechanism of SMND-309 against lung injury induced by chronic intermittent hypoxia. Int Immunopharmacol 105: 108576.
• 4 Klaska, I. P., et al. (2022). Intravitreal administration of recombinant human opticin protects against hyperoxia-induced pre-retinal neovascularization. Exp Eye Res 215: 108908.
• 5 Paco-Meza, L.-M., et al. (2022). Identification of molecular pathways and protein-protein interactions in adipose tissue-derived mesenchymal stromal cells (ASCs) under physiological oxygen concentration in a diabetic rat model. Iranian Journal of Basic Medical Sciences 25(2)
• 6 Penumatsa, K. C., et al. (2022). Vascular smooth muscle ROCK1 contributes to hypoxia-induced pulmonary hypertension development in mice. Biochemical and biophysical research communications 604: 137-143.
• 7 Wilson, M. L., et al. (2022). Effects of Anesthesia on Ozone-Induced Lung and Systemic Inflammation. Lung.
• 8 Xu, Y., et al. (2022). miR-485-5p alleviates obstructive sleep apnea syndrome with hypertension by inhibiting PI3K/AKT signaling pathway via downregulating HIF3A expression. Sleep Breath: 1-11.
• 9 Yang, J., et al. (2022). Hepatoma‐derived growth factor is associated with pulmonary vascular remodeling and PAH disease severity and survival. Pulmonary Circulation 12(1): e12007.
• 10 Zheng, Z., et al. (2022). Gene losses may contribute to subterranean adaptations in naked mole-rat and blind mole-rat. BMC biology 20(1): 1-17
• 11 AlMarabeh, S., et al. (2022). Intrarenal pelvic bradykinin-induced sympathoexcitatory reno-renal reflex is attenuated in rats exposed to chronic intermittent hypoxia. Journal of hypertension 40(1): 46-64
• 12 Bastarache, J. A., et al. (2022). A two-hit model of sepsis plus hyperoxia causes lung permeability and inflammation. Am J Physiol Lung Cell Mol Physiol 322(2): L273-L282.
• 13 Beckmann, L., et al. (2022). Regulatory T Cells Contribute to Sexual Dimorphism in Neonatal Hypoxic-Ischemic Brain Injury. Stroke 53(2): 381-390.
• 14 Bensaid, S., et al. (2022). Oxygen supplementation to limit hypoxia-induced muscle atrophy in C2C12 myotubes: comparison with amino acid supplement and electrical stimulation. Cell Tissue Res 387(2): 287-301.
• 15 Camacho-Hernandez, P., et al. (2022). Perinatal inflammation and gestational intermittent hypoxia disturbs respiratory rhythm generation and long-term facilitation in vitro: Partial protection by acute minocycline. Respir Physiol Neurobiol 297: 103829.
• 16 Carmona, M., et al. (2022). Hypoxia preconditioning increases the ability of healthy but not diabetic rat-derived adipose stromal/stem cells (ASC) to improve histological lesions of streptozotocin-induced diabetic nephropathy. Pathol Res Pract 230: 153756.
• 17 Clees, A.-S., et al. (2022). Identification of the Cysteine Protease Legumain as a Potential Chronic Hypoxia-Specific Multiple Myeloma Target Gene. Cells 11(2): 292
• 18 Cluff, E., et al. (2022). Hypoxia-inducible factor-1 alpha expression is induced by IL-2 via the PI3K/mTOR pathway in hypoxic NK cells and supports effector functions in NKL cells and ex vivo expanded NK cells. Cancer Immunol Immunother.
• 19 Cole, H. D., et al. (2022). Fine-Feature Modifications to Strained Ruthenium Complexes Radically Alter Their Hypoxic Anticancer Activity(dagger). Photochem Photobiol 98(1): 73-84.
• 20 Cui, T. X., et al. (2022). Gelsolin Attenuates Neonatal Hyperoxia-Induced Inflammatory Responses to Rhinovirus Infection and Preserves Alveolarization. Frontiers in Immunology 13.
• 21 Danielpour, D., et al. (2022). Hypoxia represses early responses of prostate and renal cancer cells to YM155 independent of HIF-1alpha and HIF-2alpha. Curr Res Pharmacol Drug Discov 3: 100076.
• 22 Dupont, M., et al. (2022). Autophagy Targeting and Hematological Mobilization in FLT3-ITD Acute Myeloid Leukemia Decrease Repopulating Capacity and Relapse by Inducing Apoptosis of Committed Leukemic Cells. Cancers (Basel) 14(2): 453.
• 23 Fouda, A. Y., et al. (2022). Preclinical investigation of Pegylated arginase 1 as a treatment for retina and brain injury. Exp Neurol 348: 113923.
• 24 Ganouna-Cohen, G., et al. (2022). Additive effects of orchiectomy and intermittent hypoxia on lung mechanics and inflammation in C57BL/6J male mice. Exp Physiol 107(1): 68-81.
• 25 Gierhardt, M., et al. (2022). Genetic deletion of p66shc and/or cyclophilin D results in decreased pulmonary vascular tone. Cardiovasc Res 118(1): 305-315.
• 26 He, Y., et al. (2022). Optimal Efficacy and Safety of Humanized Anti-Scg3 Antibody to Alleviate Oxygen-Induced Retinopathy. International journal of molecular sciences 23(1): 350.
• 27 Huang, Z., et al. (2022). AD-16 Protects Against Hypoxic-Ischemic Brain Injury by Inhibiting Neuroinflammation. Neurosci Bull.
• 28 Im, J., et al. (2022). Normobaric hyperoxia re-sensitizes paclitaxel-resistant lung cancer cells. Molecular & Cellular Toxicology.
• 29 Ismaeel, A., et al. (2022). Endothelial cell-derived pro-fibrotic factors increase TGF-beta1 expression by smooth muscle cells in response to cycles of hypoxia-hyperoxia. Biochim Biophys Acta Mol Basis Dis 1868(1): 166278.
• 30 Labuz, D. F., et al. (2022). Intrauterine Growth Restriction (IUGR) as a Potential Target for Transamniotic Stem Cell Therapy. Journal of pediatric surgery.
• 31 Lana, D., et al. (2022). Hypoxia/Ischemia-Induced Rod Microglia Phenotype in CA1 Hippocampal Slices. International journal of molecular sciences 23(3): 1422.
• 32 Li, C., et al. (2022). Under-Oil Autonomously Regulated Oxygen Microenvironments: A Goldilocks Principle-Based Approach for Microscale Cell Culture. Adv Sci (Weinh) n/a(n/a): e2104510.
• 33 Li, D., et al. (2022). Abnormal lipid droplets accumulation induced cognitive deficits in obstructive sleep apnea syndrome mice via JNK/SREBP/ACC pathway but not through PDP1/PDC pathway. Mol Med 28(1): 3.
• 34 Li, X., et al. (2022). Hypoxia-induced lncRNA RBM5-AS1 promotes tumorigenesis via activating Wnt/beta-catenin signaling in breast cancer. Cell Death Dis 13(2): 95.
• 35 Liu, W., et al. (2022). Long non-coding RNA muscleblind like splicing regulator 1 antisense RNA 1 (LncRNA MBNL1-AS1) promotes the progression of acute myocardial infarction by regulating the microRNA-132-3p/SRY-related high-mobility-group box 4 (SOX4) axis. Bioengineered 13(1): 1424-1435.
• 36 Liu, W., et al. (2022). Rapamycin ameliorates chronic intermittent hypoxia and sleep deprivation-induced renal damage via the mammalian target of rapamycin (mTOR)/NOD-like receptor protein 3 (NLRP3) signaling pathway. Bioengineered 13(3): 5537-5550.
• 37 Lu, M., et al. (2022). Mineralocorticoid Receptor Antagonist Treatment of Established Pulmonary Arterial Hypertension Improves Interventricular Dependence in SU5416-Hypoxia Rat Model. Am J Physiol Lung Cell Mol Physiol 0(0): null.
• 38 Ma, C., et al. (2022). Ubiquitinated AIF is a major mediator of hypoxia-induced mitochondrial dysfunction and pulmonary artery smooth muscle cell proliferation. Cell Biosci 12(1): 9.
• 39 Osinski, V., et al. (2022). Loss of Id3 (Inhibitor of Differentiation 3) Increases the Number of IgM-Producing B-1b Cells in Ischemic Skeletal Muscle Impairing Blood Flow Recovery During Hindlimb Ischemia. Arterioscler Thromb Vasc Biol 42(1): 6-18.
• 40 Ozgur, B., et al. (2022). Hypoxia increases expression of selected blood-brain barrier transporters GLUT-1, P-gp, SLC7A5 and TFRC, while maintaining barrier integrity, in brain capillary endothelial monolayers. Fluids Barriers CNS 19(1): 1.
• 41Pavlatovská, B., et al. (2022). Lactic Acidosis Interferes With Toxicity of Perifosine to Colorectal Cancer Spheroids: Multimodal Imaging Analysis. Front Oncol: 2527
• 42 Peeples, E. S., et al. (2022). Temporal brain microRNA expression changes in a mouse model of neonatal hypoxic-ischemic injury. Pediatr Res 91(1): 92-100.
• 43 Purandare, N., et al. (2022). Intraperitoneal Triamcinolone Reduces Postoperative Adhesions, Possibly through Alteration of Mitochondrial Function. Journal of clinical medicine 11(2): 301
• 44 Ravizzoni Dartora, D., et al. (2022). Cardiac Left Ventricle Mitochondrial Dysfunction After Neonatal Exposure to Hyperoxia: Relevance for Cardiomyopathy After Preterm Birth. Hypertension: HYPERTENSIONAHA. 121.17979
• 45 Reddy, N. M., et al. (2022). Nrf2 Is Required for Optimal Alveolar-Macrophage-Mediated Apoptotic Neutrophil Clearance after Oxidant Injury. Antioxidants 11(2): 212.
• 46 Ryan, R. M., et al. (2022). Oxygen and steroids affect the regulatory role of natriuretic peptide receptor-C on surfactant secretion by type II cells. Am J Physiol Lung Cell Mol Physiol 322(1): L13-L22.
• 47 Salazar, C., et al. (2022). Dynamic Distribution of HIG2A between the Mitochondria and the Nucleus in Response to Hypoxia and Oxidative Stress. International journal of molecular sciences 23(1): 389.
• 48 Smith, T. L., et al. (2022). eNOS controls angiogenic sprouting and retinal neovascularization through the regulation of endothelial cell polarity. Cellular and Molecular Life Sciences 79(1): 1-18
• 49 Snyder, B., et al. (2022). Aged Mouse Hippocampus Exhibits Signs of Chronic Hypoxia and an Impaired HIF-Controlled Response to Acute Hypoxic Exposures. Cells 11(3): 423.
• 50 Šranková, M., et al. (2022). Antiproliferative and Cytotoxic Activities of Fluorescein—A Diagnostic Angiography Dye. International journal of molecular sciences 23(3): 1504
• 51 Szojka, A. R. A., et al. (2022). Time course of 3D fibrocartilage formation by expanded human meniscus fibrochondrocytes in hypoxia. J Orthop Res 40(2): 495-503.
• 52 Tao, Y., et al. (2022). Long noncoding RNA LUCAT1 enhances the survival and therapeutic effects of mesenchymal stromal cells post-myocardial infarction. Mol Ther Nucleic Acids 27: 412-426.
• 53 Vandenberg, G. G., et al. (2022). Mitochondrial bioenergetics of astrocytes in Fragile X syndrome: new perspectives on culture conditions and sex effects. Am J Physiol Cell Physiol 322(2): C125-C135.
• 54 Won, T., et al. (2022). Endothelial thrombomodulin downregulation caused by hypoxia contributes to severe infiltration and coagulopathy in COVID-19 patient lungs. EBioMedicine 75: 103812.
• 55 Xu, P., et al. (2022). Erythrocyte transglutaminase-2 combats hypoxia and chronic kidney disease by promoting oxygen delivery and carnitine homeostasis. Cell Metab 34(2): 299-316 e296.
• 56 Xu, Y., et al. (2022). A novel regulatory mechanism network mediated by lncRNA TUG1 that induces the impairment of spiral artery remodeling in Preeclampsia. Mol Ther.
• 57 Yang, K., et al. (2022). Lactate promotes macrophage HMGB1 lactylation, acetylation, and exosomal release in polymicrobial sepsis. Cell Death Differ 29(1): 133-146.
• 58 Zhang, G., et al. (2022). Sulforaphane Does Not Protect Right Ventricular Systolic and Diastolic Functions in Nrf2 Knockout Pulmonary Artery Hypertension Mice. Cardiovasc Drugs Ther.
• 59 Zhang, J. S., et al. (2022). microRNA-455-5p alleviates neuroinflammation in cerebral ischemia/reperfusion injury. Neural Regen Res 17(8): 1769-1775.
• 60 Zhang, J., et al. (2022). Hypoxia promotes steroidogenic competence of buffalo (Bubalus bubalis) theca cells. Theriogenology 180: 113-120.
• 61 Zhao, C., et al. (2022). Dynamic Multiscale Regulation of Perfusion Recovery in Experimental Peripheral Arterial Disease: A Mechanistic Computational Model. JACC Basic Transl Sci 7(1): 28-50.
• 62 Adams, K. V., et al. (2021). Constraint-induced movement therapy promotes motor recovery after neonatal stroke in the absence of neural precursor activation. Eur J Neurosci 53(4): 1334-1349.
• 63 Aghajanian, A., et al. (2021). Decreased inspired oxygen stimulates de novo formation of coronary collaterals in adult heart. J Mol Cell Cardiol 150: 1-11.
• 64 Al Khazal, F., et al. (2021). Unexpected obesity, rather than tumorigenesis, in a conditional mouse model of mitochondrial complex II deficiency. FASEB J 35(2): e21227.
• 65 Alhalhooly, L., et al. (2021). Dynamic cellular biomechanics in responses to chemotherapeutic drug in hypoxia probed by atomic force spectroscopy. Oncotarget 12(12): 1165-1177.
• 66 Al-Hilal, T. A., et al. (2021). Design, synthesis and biological evaluations of a long-acting, hypoxia-activated prodrug of fasudil, a ROCK inhibitor, to reduce its systemic side-effects. J Control Release 334: 237-247.
• 67 Alicea-Torres, K., et al. (2021). Immune suppressive activity of myeloid-derived suppressor cells in cancer requires inactivation of the type I interferon pathway. Nat Commun 12(1): 1717.
• 68 Allan, K. C., et al. (2021). Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function. Cell Stem Cell 28(2): 257-272 e211.
• 69 Allmon, E., et al. (2021). The influence of hypoxia on the cardiac transcriptomes of two estuarine species – C. variegatus and F. grandis. Comp Biochem Physiol Part D Genomics Proteomics 39: 100837.
• 70 AlMarabeh, S., et al. (2021). Chronic intermittent hypoxia impairs diuretic and natriuretic responses to volume expansion in rats with preserved low-pressure baroreflex control of the kidney. Am J Physiol Renal Physiol 320(1): F1-F16.
• 71 Alzahrani, A. A., et al. (2021). beta-Adrenoceptor blockade prevents carotid body hyperactivity and elevated vascular sympathetic nerve density induced by chronic intermittent hypoxia. Pflugers Arch 473(1): 37-51.
• 72 Amin, S. M., et al. (2021). Efficacy of Aflibercept Treatment and Its Effect on the Retinal Perfusion in the Oxygen-Induced Retinopathy Mouse Model of Retinopathy of Prematurity. Ophthalmic Res 64(1): 91-98.
• 73 Arce, C., et al. (2021). Hypoxia Increases Nitric Oxide-Dependent Inhibition of Angiogenic Growth. International Journal of Translational Medicine 1(3): 366-380.
• 74 Arias-Reyes, C., et al. (2021). Mice and Rats Display Different Ventilatory, Hematological, and Metabolic Features of Acclimatization to Hypoxia. Front Physiol 12: 647822.
• 75 Atala, A., et al. (2021). Regen med therapeutic opportunities for fighting COVID-19. Stem Cells Transl Med 10(1): 5-13.
• 76 Bapat, A., et al. (2021). Hypoxia promotes erythroid differentiation through the development of progenitors and proerythroblasts. Exp Hematol 97: 32-46 e35.
• 77 Barreto-Duran, E., et al. (2021). 3D Multicellular Spheroid for the Study of Human Hematopoietic Stem Cells: Synergistic Effect Between Oxygen Levels, Mesenchymal Stromal Cells and Endothelial Cells. Journal of Blood Medicine 12: 517.
• 78 Bazilio, D. S., et al. (2021). Distinct cardiovascular and respiratory responses to short-term sustained hypoxia in juvenile Sprague Dawley and Wistar Hannover rats. Auton Neurosci 230: 102746.
• 79 Berghausen, E. M., et al. (2021). Disrupted PI3K subunit p110alpha signaling protects against pulmonary hypertension and reverses established disease in rodents. J Clin Invest 131(19).
• 80Bernhard, J. M., et al. (2021). Impacts of multiple stressors on a benthic foraminiferal community: A long-term experiment assessing response to ocean acidification, hypoxia and warming. Frontiers in Marine Science
• 81 Bodkin, D., et al. (2021). Neonatal intermittent hypoxia, fish oil, and/or antioxidant supplementation on gut microbiota in neonatal rats. Pediatr Res.
• 82 Cahill, L. S., et al. (2021). Sex differences in modulation of fetoplacental vascular resistance in growth-restricted mouse fetuses following betamethasone administration: comparisons with human fetuses. Am J Obstet Gynecol MFM 3(1): 100251.
• 83 Cai, C., et al. (2021). Lymphocytic microparticles suppress retinal angiogenesis via targeting Muller cells in the ischemic retinopathy mouse model. Exp Cell Res 399(2): 112470.
• 84 Cao, X., et al. (2021). TRB3 mediates vascular remodeling by activating the MAPK signaling pathway in hypoxic pulmonary hypertension. Respir Res 22(1): 312.
• 85 Casalino-Matsuda, S. M., et al. (2021). Hypercapnia selectively modulates LPS-induced changes in innate immune and DNA replication-related gene transcription in the macrophage. Interface Focus 11(2): 20200039.
• 86 Castillo, M. C., et al. (2021). NIN-like protein7 and PROTEOLYSIS6 functional interaction enhances tolerance to sucrose, ABA, and submergence. Plant Physiol 187(4): 2731-2748.
• 87 Chandran, R. R., et al. (2021). Distinct roles of KLF4 in mesenchymal cell subtypes during lung fibrogenesis. Nat Commun 12(1): 7179.
• 88 Chang, C. C., et al. (2021). Three-dimensional Imaging Coupled with Topological Quantification Uncovers Retinal Vascular Plexuses Undergoing Obliteration. Theranostics 11(3): 1162-1175.
• 89 Chang, J., et al. (2021). Intrauterine growth restriction followed by oxygen support uniquely interferes with genetic regulators of myelination. eneuro.
• 90 Chaubey, S., et al. (2021). alpha1,3-Fucosyltransferase-IX, an enzyme of pulmonary endogenous lung stem cell marker SSEA-1, alleviates experimental bronchopulmonary dysplasia. Pediatr Res 89(5): 1126-1135.
• 91 Chen, C. M., et al. (2021). Immunization with anti-Tn immunogen in maternal rats protects against hyperoxia-induced kidney injury in newborn offspring. Pediatr Res 89(3): 476-482.
• 92 Chen, C. M., et al. (2021). Maternal antibiotic exposure disrupts microbiota and exacerbates hyperoxia-induced lung injury in neonatal mice. Pediatr Res 90(4): 776-783.
• 93 Chen, J. E., et al. (2021). Matrix Hyaluronic Acid and Hypoxia Influence a CD133(+) Subset of Patient-Derived Glioblastoma Cells. Tissue Eng Part A 0(ja): null.
• 94 Chen, J., et al. (2021). A drug-tunable Flt23k gene therapy for controlled intervention in retinal neovascularization. Angiogenesis 24(1): 97-110.
• 95 Chen, J., et al. (2021). Exploiting the acquired vulnerability of cisplatin-resistant tumors with a hypoxia-amplifying DNA repair–inhibiting (HYDRI) nanomedicine. Sci Adv 7(13): eabc5267.
• 96 Chen, J., et al. (2021). The protective role of SOD1 overexpression in central mediation of bradycardia following chronic intermittent hypoxia in mice. Am J Physiol Regul Integr Comp Physiol 320(3): R317-R330.
• 97 Chen, L., et al. (2021). Chronic Exposure to Hypoxia Inhibits Myelinogenesis and Causes Motor Coordination Deficits in Adult Mice. Neurosci Bull 37(10): 1397-1411.
• 98 Chen, Y., et al. (2021). The lncRNA Malat1 regulates microvascular function after myocardial infarction in mice via miR-26b-5p/Mfn1 axis-mediated mitochondrial dynamics. Redox Biol 41: 101910.
• 99 Cheng, W. H., et al. (2021). Hypoxia-induced preadipocyte factor 1 expression in human lung fibroblasts through ERK/PEA3/c-Jun pathway. Mol Med 27(1): 69.
• 100 Cheng, W. H., et al. (2021). Pref-1 induced lung fibroblast differentiation by hypoxia through integrin alpha5beta1/ERK/AP-1 cascade. Eur J Pharmacol 909: 174385.
• 101 Chiang, C. T., et al. (2021). High-throughput microscopy reveals the impact of multifactorial environmental perturbations on colorectal cancer cell growth. GigaScience 10(4): giab026.
• 102 Cho, H., et al. (2021). Dendrimer-Triamcinolone Acetonide Reduces Neuroinflammation, Pathological Angiogenesis, and Neuroretinal Dysfunction in Ischemic Retinopathy. Adv Ther (Weinh) 4(2): 2000181.
• 103 Christou, H., et al. (2021). Carbonic anhydrase inhibition improves pulmonary artery reactivity and nitric oxide-mediated relaxation in sugen-hypoxia model of pulmonary hypertension. Am J Physiol Regul Integr Comp Physiol 320(6): R835-R850.
• 104 Clapper, E., et al. (2021). The regulation of bcr-abl in hypoxia is through the mTOR pathway. Leukemia & Lymphoma 62(4): 967-978
• 105 Cole, H. D., et al. (2021). Anticancer Agent with Inexplicable Potency in Extreme Hypoxia: Characterizing a Light-Triggered Ruthenium Ubertoxin. J Am Chem Soc.
• 106 Compton, S. L. E., et al. (2021). Adaptation of metabolism to multicellular aggregation, hypoxia and obese stromal cell incorporation as potential measure of survival of ovarian metastases. Exp Cell Res 399(1): 112397.
• 107 Cooper, J. F., et al. (2021). Stress increases in exopher-mediated neuronal extrusion require lipid biosynthesis, FGF, and EGF RAS/MAPK signaling. Proc Natl Acad Sci U S A 118(36).
• 108 Correia, M. J., et al. (2021). Aryl Hydrocarbon Receptor and Cysteine Redox Dynamics Underlie (Mal)adaptive Mechanisms to Chronic Intermittent Hypoxia in Kidney Cortex. Antioxidants (Basel) 10(9): 1484.
• 109 Cortese, R., et al. (2021). Gestational sleep apnea perturbations induce metabolic disorders by divergent epigenomic regulation. Epigenomics 13(10): 751-765.
• 110 Coyle, R. C., et al. (2021). Targeting HIF-alpha for robust prevascularization of human cardiac organoids. J Tissue Eng Regen Med 15(2): 189-202.
• 111 Cui, T. X., et al. (2021). Lung CD103(+)dendritic cells and Clec9a signaling are required for neonatal hyperoxia-induced inflammatory responses to rhinovirus infection. Am J Physiol Lung Cell Mol Physiol 320(2): L193-L204.
• 112 Cyr-Depauw, C., et al. (2021). Characterization of the innate immune response in a novel murine model mimicking bronchopulmonary dysplasia. Pediatr Res 89(4): 803-813.
• 113 da Silva, M. P., et al. (2021). Chronic intermittent hypoxia increases excitability and synaptic excitation of protrudor and retractor hypoglossal motoneurones. J Physiol 599(6): 1917-1932.
• 114 Dai, W., et al. (2021). Effects of Op2113 on Myocardial Infarct Size and No Reflow in a Rat Myocardial Ischemia/reperfusion Model. Cardiovascular Drugs and Therapy: 1-11
• 115 Dani, C., et al. (2021). Neurotoxicity of Unconjugated Bilirubin in Neonatal Hypoxic-Ischemic Brain Injury in vitro. Front Pediatr 9: 659477.
• 116 Das, P., et al. (2021). Chitin-Derived AVR-48 Prevents Experimental Bronchopulmonary Dysplasia (BPD) and BPD-Associated Pulmonary Hypertension in Newborn Mice. Int J Mol Sci 22(16): 8547.
• 117 Deprez, A., et al. (2021). Transient neonatal exposure to hyperoxia, an experimental model of preterm birth, leads to skeletal muscle atrophy and fiber type switching. Clin Sci (Lond) 135(22): 2589-2605.
• 118 Desjarlais, M., et al. (2021). Tyrosine-Protein Phosphatase Non-receptor Type 9 (PTPN9) Negatively Regulates the Paracrine Vasoprotective Activity of Bone-Marrow Derived Pro-angiogenic Cells: Impact on Vascular Degeneration in Oxygen-Induced Retinopathy. Front Cell Dev Biol 9: 679906.
• 119 Dias, G. F., et al. (2021). Uremia and Inadequate Oxygen Supply Induce Eryptosis and Intracellular Hypoxia in Red Blood Cells. Cell Physiol Biochem 55(4): 449-459.
• 120 Díaz-García, E., et al. (2021). Intermittent Hypoxia Mediates Paraspeckle Protein-1 Upregulation in Sleep Apnea. Cancers 13(15): 3888.
• 121 Dizin, E., et al. (2021). Activation of the Hypoxia-Inducible Factor Pathway Inhibits Epithelial Sodium Channel–Mediated Sodium Transport in Collecting Duct Principal Cells. Journal of the American Society of Nephrology 32(12): 3130-3145
• 122 Domingos-Souza, G., et al. (2021). Alpha adrenergic receptor signaling in the hypothalamic paraventricular nucleus is diminished by the chronic intermittent hypoxia model of sleep apnea. Exp Neurol 335: 113517.
• 123 Domogauer, J. D., et al. (2021). Acquired radioresistance in cancer associated fibroblasts is concomitant with enhanced antioxidant potential and DNA repair capacity. Cell Commun Signal 19(1): 30.
• 124 Dong, D., et al. (2021). Hyperoxia sensitizes hypoxic HeLa cells to ionizing radiation by downregulating HIF1alpha and VEGF expression. Mol Med Rep 23(1).
• 125 Drummond, S. E., et al. (2021). The role of NADPH oxidase in chronic intermittent hypoxia-induced respiratory plasticity in adult male mice. Respir Physiol Neurobiol 292: 103713.
• 126 Dumas, P. Y., et al. (2021). Dual Inhibition of FLT3 and AXL by Gilteritinib Overcomes Hematopoietic Niche-Driven Resistance Mechanisms in FLT3-ITD Acute Myeloid Leukemia. Clin Cancer Res 27(21): 6012-6025.
• 127 Dvořák, A., et al. (2021). The effects of bilirubin and lumirubin on metabolic and oxidative stress markers. Frontiers in pharmacology 12: 26
• 128 Dwight, T., et al. (2021). Functional significance of germline EPAS1 variants. Endocr Relat Cancer 28(2): 97-109.
• 129 Dykstra, K. M., et al. (2021). Inhibiting autophagy targets human leukemic stem cells and hypoxic AML blasts by disrupting mitochondrial homeostasis. Blood Adv 5(8): 2087-2100.
• 130 Dzah, C. S., et al. (2021). Effects of pretreatment and type of hydrolysis on the composition, antioxidant potential and HepG2 cytotoxicity of bound polyphenols from Tartary buckwheat (Fagopyrum tataricum L. Gaerth) hulls. Food Res Int 142: 110187.
• 131 El Hafny-Rahbi, B., et al. (2021). Tumour angiogenesis normalized by myo-inositol trispyrophosphate alleviates hypoxia in the microenvironment and promotes antitumor immune response. J Cell Mol Med 25(7): 3284-3299.
• 132 Elkhenany, H. A., et al. (2021). Bone Marrow Mesenchymal Stem Cell-Derived Tissues are Mechanically Superior to Meniscus Cells. Tissue Eng Part A 27(13-14): 914-928.
• 133 Fachi, J. L., et al. (2021). Hypoxia enhances ILC3 responses through HIF-1alpha-dependent mechanism. Mucosal Immunol 14(4): 828-841.
• 134 Fang, Y. Y., et al. (2021). 7,8-Dihydroxyflavone protects retinal ganglion cells against chronic intermittent hypoxia-induced oxidative stress damage via activation of the BDNF/TrkB signaling pathway. Sleep Breath: 1-9.
• 135 Framnes-DeBoer, S. N., et al. (2021). The timing of intermittent hypoxia differentially affects macronutrient intake and energy substrate utilization in mice. Am J Physiol Endocrinol Metab 321(4): E543-E550.
• 136 Gabrielli, N. M., et al. (2021). TRAF2 is a novel ubiquitin E3 ligase for the Na, K-ATPase β-subunit that drives alveolar epithelial barrier dysfunction in hypercapnia. Frontiers in Cell and Developmental Biology 9: 1744
• 137 Gao, S., et al. (2021). Complement promotes endothelial von Willebrand factor and angiopoietin-2 release in obstructive sleep apnea. Sleep 44(4).
• 138 Garcia, D., et al. (2021). Short exposure to hyperoxia causes cultured lung epithelial cell mitochondrial dysregulation and alveolar simplification in mice. Pediatr Res 90(1): 58-65.
• 139 Gauthier, A. G., et al. (2021). The Positive Allosteric Modulation of alpha7-Nicotinic Cholinergic Receptors by GAT107 Increases Bacterial Lung Clearance in Hyperoxic Mice by Decreasing Oxidative Stress in Macrophages. Antioxidants (Basel) 10(1): 135.
• 140 Ge, H., et al. (2021). Ambroxol Upregulates Glucocerebrosidase Expression to Promote Neural Stem Cells Differentiation Into Neurons Through Wnt/β-Catenin Pathway After Ischemic Stroke. Frontiers in Molecular Neuroscience 13: 263
• 141 Gerace, E., et al. (2021). NIR Laser Photobiomodulation Induces Neuroprotection in an In Vitro Model of Cerebral Hypoxia/Ischemia. Mol Neurobiol 58(10): 5383-5395.
• 142 Getsy, P. M., et al. (2021). Carotid sinus nerve transection abolishes the facilitation of breathing that occurs upon cessation of a hypercapnic gas challenge in male mice. J Appl Physiol (1985) 131(2): 821-835.
• 143 Getsy, P. M., et al. (2021). Short-term facilitation of breathing upon cessation of hypoxic challenge is impaired in male but not female endothelial NOS knock-out mice. Sci Rep 11(1): 18346.
• 144 Getsy, P. M., et al. (2021). Ventilatory Responses During and Following Hypercapnic Gas Challenge are Impaired in Male but Not Female Endothelial NOS Knock-out Mice. Scientific Reports.
• 145 Ginerete, R. P., et al. (2021). Repeated episodes of transient reduction of oxygen exposure simulating aircraft cabin conditions enhance resilience to stress in mice. Eur J Neurosci 54(9): 7109-7124.
• 146 Głuszko, A., et al. (2021). Small Extracellular Vesicles from Head and Neck Squamous Cell Carcinoma Cells Carry a Proteomic Signature for Tumor Hypoxia. Cancers 13(16): 4176
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