Closed incubators, hoods
and chambers for
pathophysiologic conditions
in COVID research
Options for Adding Hypoxic Control Capabilities to the Lab
How do I get cytocentric equipment FOR SIMULATING physioxia/hypoxia?
Step 1
Step 2
LET US HELP YOU REFINE OR REPLACE YOUR INCUBATOR WITH CYTOCENTRIC EQUIPMENT
Step 3
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Publications

Li Y, et al. Physiological and pathological regulation of ACE2, the SARS-CoV-2 receptor. Pharmacol Res. 2020 Apr 14:104833. [Epub ahead of print]
Joshi S, et al. Hypoxic regulation of angiotensin-converting enzyme 2 and Mas receptor in human CD34(+) cells. J Cell Physiol. 2019 Nov;234(11):20420-20431.
Zhang R, et al. Role of HIF-1alpha in the regulation ACE and ACE2 expression in hypoxic human pulmonary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2009 Oct;297(4):L631-40.
Mason RJ. Pathogenesis of COVID-19 from a cell biology perspective. Eur Respir J. 2020 Apr 16;55(4).
Kumar A, et al. Quantifying the magnitude of the oxygen artefact inherent in culturing airway cells under atmospheric oxygen versus physiological levels. FEBS Lett. 2016 Jan;590(2):258-69.
Blog Posts

Interview with Cytocentric Visionary: Ian Mudway, Lecturer – Respiratory Toxicology Lung Biology Group , King’s College London, Part One: What Are the Fundamental Things That We Absolutely Have To Get Right?
CytoCentric Blog – More Tips for Extreme Oxygen Studies: Anoxia, Hypoxia, Physioxia and Hyperphysioxia
CytoCentric Blog – The Biology of HIF Proteins Impacts the Outcome of Your Experiments in Physiologic Oxygen: Considerations for protocol design

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