Cytocentric-Blog

cytocentric visionaries ry p4Cytocentric Visionaries: Randy Yerden, CEO BioSpherix

Part Four: A Trachea for Hannah

This post contains excerpts from an interview that Dr. Alicia Henn, Chief Scientific Officer of BioSpherix, conducted with Randy Yerden, Founder and CEO of BioSpherix.

In part three of our interview, we discussed how cytocentric principles benefit cell based assays. Today we talk about the incredible experience of participating in groundbreaking surgery to implant a stem-cell bearing manufactured trachea into a toddler. Continue reading to learn how GMP cell therapy for the artificial trachea was performed with our donated Xvivo systems.

cytocentric visionaries ry p3

Cytocentric Visionaries: Randy Yerden, CEO BioSpherix

Part Three: Seeing Cytocentric Principles in Action

This post contains excerpts from an interview that Dr. Alicia Henn, Chief Scientific Officer of BioSpherix, conducted with Randy Yerden, Founder and CEO of BioSpherix.

In the 2nd part of this interview, we talked about the potentially reducing animal testing with relevant cell based assays by applying cytocentric principles. Today we talk about seeing Cytocentric Principles in action in research. Continue reading to learn how cytocentric principles have benefited research with cell based assays.

cytocentric visionaries ry p2Cytocentric Visionaries: Randy Yerden, CEO BioSpherix

Part Two: Physiologically-Relevant Cell-Based Assays to Reduce Wasteful Animal Testing

This post contains excerpts from an interview that Dr. Alicia Henn, Chief Scientific Officer of BioSpherix, conducted with Randy Yerden, Founder and CEO of BioSpherix.

In Part One, we talked about how the Cytocentric Principles were formed from decades of insight from top scientists about the needs of cells. Today we talk about how the total quality concepts in the Cytocentric Principles can reduce animal testing through relevant cell-based assays.

cytocentric visionaries ry p1Cytocentric Visionaries: Randy Yerden, CEO BioSpherix, Ltd.

Part One: Origin of the Cytocentric Principles

Randy Yerden is the Founder and Chief Executive Officer of BioSpherix, Ltd. He created the Cytocentric Principles as a way to describe the fundamental biologic factors that drive the development of all of the products at BioSpherix. Here Chief Scientific Officer, Alicia Henn interviews Randy about how the Cytocentric Principles were formed. In part one of a multi-part series, we discuss applying cytocentric principles in future science research.

bp028.5 image001Reproducibility and Variability in Critical Cell Culture Parameters - Temperature

Keep the cells in log-phase growth for batch after batch. Rinse and repeat. The cells should be the same every time you need them. Seems like a simple thing, right? 

But it never is that easy to get consistent cell growth. That’s why we spend so much time and money checking the cells. Do they still express the right markers? Before researchers even get to the biologically question at hand, a lot of space in scientific reports is dedicated to the simple question; “Are the cells being used the type of cell that they are supposed to be?”