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Biocontainment: Cells Need Technician Protection

“I’ve been handling cells this way for years and I’VE never gotten sick.”

How many times have you heard that, and doubted it?

Continue reading to learn why biosafety and biocontainment have become increasingly important.

Confidence in handling potentially dangerous cells, tissues, and vectors, can easily become complacency. Now in an uncertain era of CRISPR/Cas GMOs and gene drives, biocontainment and biosafety have taken on more urgency.

Following recent laboratory biosafety lapses, NIH is updating its biosafety policies and the White House recently released their recommendations for increased biosafety. While these were aimed primarily at Federal facilities, it also called for an increased application of best practices at non-Federal institutions as well to achieve “a laboratory culture of responsible conduct.”

Across industries and around the world, a workplace culture of safety is the product of organizational, managerial, and human factors. Engineered safety measures, put in place by management, help prevent human failures by front-line workers from becoming disasters. [1] While establishing a biosafety-first culture from top management down to the frontline laboratory worker is necessary, it is smart to start by providing frontline laboratory workers with equipment that enforces safe practices.

In cytocentric equipment design, the focus is on the cells and their needs. However, if you put all laboratory equipment that the cells need into an enclosed space, where they have unbroken physiologic conditions, those cells are necessarily separated from the open laboratory and personnel. By incorporating cytocentric principles like full-time protection of the cellular environment into equipment design, you get biocontainment and the biosafety that technicians need as well.

Be sure to follow us as we talk to leaders in the biosafety field about different ways cytocentric equipment can enhance biocontainment and biosafety in the laboratory.

For more information about biocontainment and biosafety in the cytocentric laboratory, contact us here.

1. Reason, J., The contribution of latent human failures to the breakdown of complex systems. Philosophical Transactions of the Royal Society B: Biological Sciences, 1990. 327(1241): p. 475-484.

 


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About The Author

Alicia D Henn, PhD, MBA

Alicia D Henn, PhD, MBA

Chief Scientific Officer of BioSpherix, Ltd

 

 

Alicia Henn has been the Chief Scientific Officer of BioSpherix, Ltd since 2013. Previously, she was a researcher at the Center for Biodefense Immune Modeling in Rochester, NY. Alicia obtained her PhD in molecular pharmacology and cancer therapeutics from Roswell Park Cancer Institute in Buffalo, NY and her MBA from the Simon School at University of Rochester in Rochester, NY.

ahenn@biospherix.com

 

 

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