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Medical research is illuminating more and more roles bioactive gases play in living organisms. Both physiologic and pathologic functions are being discovered that will eventually enable doctors to treat and even cure human disease. However, it can only be studied if it can be recreated.
BioSpherix offers oxygen profiling with our sophisticated OxyCycler A-Series controllers for in vivo models. The OxyCycler independently controls in multiple chambers and can hold any setpoint for any length of time, manipulate any rate of change between setpoints and cycle any profile any number of times in any chamber.
The A-Series allows you to easily create any profile you need with full range oxygen control (0.1% to 99.9%) and/or CO2 control (0.1% to 20.0%) as well as other bioactive gas control such as CO, NO, and O3.
HOW IT WORKS
The OxyCycler sits outside your incubator and is attached to the chambers within the incubator by umbilicals with actuator pods on the ends. The pods contain the bioactive gas sensor, a gas nozzle and mounting hardware.
Our A-Chambers are specifically designed for the actuator pods to mount to. The OxyCycler remotely senses the gas concentration in the chamber and infuses gas until it reaches your setpoint. The OxyCycler comes with a computer system for an easy interface, real-time trend charting, data logging and remote operation.
Since the OxyCycler works in semi-sealed chambers, the profiles are normobaric. Nitrogen and oxygen gas infusions displace the chamber gas and pressure remains equilibrated with outside pressure.
Any gas supply can be utilized by the OxyCycler but some supplies may be more efficient. Compressed is best with low consumption, generators are best with high consumption and liquid is best in the middle.
Our OxyCycler A-Series has many different options. This is an example of our OxyCycler AT controller for toxic gas control. These systems control O2, CO, NO, O3 or CO2 and any combination of these bioactive gases. The animal chambers with the AT system are enclosed in a fume shroud with an exhaust fan.
The toxic gases that leak of the ventilation holes in the chambers are whisked away within the fume shrouds and never build up in the room. The system also includes a sensor that monitors and logs the gases in the room outside the shrouds and has an alarm if any dangerous gases are released into the room.
PROFILES
The OxyCycler allows you to create any change in the bioactive gas concentration. You can independently control and profile up to four chambers simultaneously. For example you could have one control profile and up to three experimental profiles.
Up to 17 different profiles can be stored and each can be run in any of the four chambers at any time. Chambers can have the same profile simultaneously or staggered to begin at different times.
Each profile can have 1 to 20 setpoints and can be from 0.1% to 99.9% oxygen. The rate between setpoints can be 0 - 999 minutes with resolution to seconds. Profiles can be cycled continuously or 1 to 99 times. Examples of profiles are shown at right
For a downloadable and printable version click here.
Downloadable and printable version for the OxyCycler AT Series.
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