Applications

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- reproducibly model high-altitude hypoxia

- reproducibly model dynamic hypoxia (ascent) and reoxygenation (descent)

Cell Research - hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - hypoxia chamber(s) with dynamic control of O2 and CO2 - C42 & C-Chamber(s)

Animal Modeling - hypoxia chamber with static control of O2 - P360 & A-Chamber

Animal Modeling - hypoxia chamber(s) with dynamic control of O2 - A84 & A-Chamber(s)


- simulate physiological blood O2 levels

- simulate bone marrow O2 niche

- reproducibly model hypoxemia

- reproducibly model hyperoxemia

- induce RBC sickling

- maintain HSC quiescence

- increase HSC yield

- enhance HSC repopulating activity

- promote HSC differentiation

Cell Research - physiologic oxygen chamber, hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - physiologic oxygen incubator and hood system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell handling chamber(s) - Xvivo System

Animal Modeling - hypoxia chamber with static control of O2 - P360 & A-Chamber


- simulate solid tumor tissue O2 levels

- reproducibly model hypoxic tumor core

- simulate blood cancer niche

- induce cancer stem-like traits

- reproducibly model tumor hypoxia/reoxygenation

Cell Research - hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - hypoxic incubator and hood system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell handling chamber(s) - Xvivo System


- provide reproducible PPM-scale CO exposures

- reproducibly model cellular CO signaling

- reproducibly model therapeutic Carbon Monoxide

Cell Research - carbon monoxide chamber with dynamic control of parts per million CO, O2, and CO2 - GT4181C & C-Chamber

Animal Modeling - carbon monoxide chamber(s) with dynamic control of parts per million CO - AT42CO & A-Chamber(s)


- simulate cardiac tissue O2 levels

- promote cardiac lineage differentiation

- induce VEGF expression and angiogenesis

- reproducibly model myocardial ischemia reperfusion injury

Cell Research - physiologic oxygen chamber, hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - physiologic oxygen chamber(s), hypoxia chamber(s) with dynamic control of O2 and CO2 - C42 & C-Chamber(s)

Animal Modeling - hypoxia chamber with static control of O2 - P360 & A-Chamber


- analyze cells within non-interrupted, physiologically relevant conditions

Cell-Based Assays - physiologic oxygen chamber, hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell-Based Assays - physiologic oxygen incubator and hood system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell handling chamber(s) - Xvivo System


- simulate cellular physiological O2 levels

- reduce DNA damage

- remove ROS/oxidative stress artifact

- induce oxidative stress/ROS production

Cell Research - physiologic oxygen chamber, hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - physiologic oxygen incubator and hood system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell handling chamber(s) - Xvivo System


- image cells within non-interrupted, physiologically relevant conditions

Cell Research - physiologic oxygen chamber, hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - physiologic oxygen incubator and hood system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell microscopy chamber(s) - Xvivo System


- reproducibly model hypoxia-circadian patterns

Cell Research - hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - hypoxia chamber(s) with dynamic control of O2 and CO2 - C42 & C-Chamber(s)

Animal Modeling - hypoxia chamber with static control of O2 - P360 & A-Chamber

Animal Modeling - hypoxia chamber(s) with dynamic control of O2 - A84 & A-Chamber(s)


- simulate physiologic intrauterine O2 levels

- simulate physiologic embryonic/fetal tissue O2 levels

- reproducibly model developmental/gestational hypoxia

- reproducibly perform trophoblast models of pre-eclampsia

- reproducibly model placental/intrauterine hypoxia

Cell Research - physiologic oxygen chamber, hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - physiologic oxygen incubator and hood system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell handling chamber(s) - Xvivo System

Animal Modeling - hypoxia chamber with static control of O2 - P360 & A-Chamber


- simulate physiologic pancreatic tissue O2 levels

- reproducibly model hypoxic beta cell/pancreatic islet transplant conditions

Cell Research - physiologic oxygen chamber, hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - physiologic oxygen incubator and hood system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell handling chamber(s) - Xvivo System


- reproducibly model exercise induced hypoxia

Cell Research - hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - hypoxia chamber(s) with dynamic control of O2 and CO2 - C42 & C-Chamber(s)

Cell Research - physiologic oxygen incubator and hood system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell handling chamber(s) - Xvivo System


- simulate physiologic GI tissue oxygen levels

Cell Research - physiologic oxygen chamber, hypoxia chamber with static control of O2 and CO2 -

C21 & C-Chamber

Cell Research - physiologic oxygen incubator and hood system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell handling chamber(s) -

Xvivo System


- preserve genetic integrity

- remove ROS/oxidative stress artifact

- decrease genetic aberration

Cell Research - physiologic oxygen chamber, hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - physiologic oxygen incubator and hood system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell handling chamber(s) - Xvivo System


- simulate physiologic liver O2 levels

- induce hepatocyte differentiation

- reproducibly model metabolic zonation of liver

- improve hepatocyte phenotypic stability

Cell Research - physiologic oxygen chamber, hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - physiologic oxygen incubator and hood system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell handling chamber(s) - Xvivo System


- induce HIF-1 expression

- maintain HIF-1 stabilization

Cell Research - hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - hypoxic incubator and cabinet system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell handling chamber(s) - Xvivo System


- reproducibly model with controlled CO2 levels

- ensure environmental quality with limit-control of PPM CO2 levels

Animal Modeling - hypercapnia chamber with static control of CO2 - P120 & A-Chamber

Animal Modeling - chamber with limit control of parts per million CO2 - P120PPM & A-Chamber

Animal Modeling - hypercapnia chamber(s) with dynamic control of CO2 - A44C & A-Chamber(s)


- simulate bone marrow niche O2 levels

- simulate physiologic lymphatic tissue O2 levels

- model pathologic hypoxia conditions during injury/disease

- ensure relevant immune cell function

- reproducibly model conditions during immune cell homing/migration

- increase immune cell expansion

- control immune cell fate decisions

Cell Research - physiologic oxygen chamber, hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - physiologic oxygen chamber(s), hypoxia chamber(s) with dynamic control of O2 and CO2 - C42 & C-Chamber(s)

Cell Research - physiologic oxygen incubator and hood system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell handling chamber(s) - Xvivo System


- simulate physiologic tissue O2 levels

- model pathologic hypoxia conditions

- increase predictive ability of cell-based assays

- improve correlation between in vitro and in vivo data

Cell-Based Assays - physiologic oxygen chamber, hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell-Based Assays - physiologic oxygen incubator and hood system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell analysis chamber(s) - Xvivo System


- remove ROS/oxidative stress artifact

- model pathologic hypoxia conditions

- increase predictive ability of cell-based toxicology assays

- improve correlation between in vitro and in vivo data

Cell-Based Assays - physiologic oxygen chamber, hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell-Based Assays - physiologic oxygen incubator and hood system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell analysis chamber(s) - Xvivo System


- reproducibly control intermittent hypoxia

Cell Research - intermittent hypoxia chamber(s) with dynamic control of O2 and CO2 - C42 & C-Chamber(s)

Animal Modeling - intermittent hypoxia chamber with dynamic control of O2 - A41 & A-Chamber

Animal Modeling - intermittent hypoxia chamber(s) with dynamic control of O2 - A84 & A-Chamber(s)

Animal Modeling - accessory kit for rapid profiling upgrade to intermittent hypoxia chamber(s) - Quick & Quiet Profiler


- simulate physiologic kidney tissue O2 levels

- reproducibly model kidney injury

Cell Research - physiologic oxygen chamber, hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Animal Modeling - hypoxia chamber with static control of O2 - P360 & A-Chamber


- ensure physiologic baseline metabolic phenotype

- remove oxidative stress artifact from stressed metabolic phenotype

Cell Research - physiologic oxygen chamber, hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - physiologic oxygen incubator and hood system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell handling chamber(s) - Xvivo System


- simulate neurological tissue physiological O2 levels

- reproducibly model ischemia/OGD/stroke

- control neural phenotype lineage commitment

- reproducibly model anxiety

- induce neural plasticity response

Cell Research - physiologic oxygen chamber, hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - hypoxia chamber(s) with dynamic control of O2 and CO2 - C42 & C-Chamber(s)

Animal Modeling - hypoxia chamber with static control of O2 - P360 & A-Chamber

Animal Modeling - hypoxia chamber(s) with static control of O2 - A84 & A-Chamber(s)


- provide reproducible PPM-scale NO exposures

- reproducibly model cellular NO signaling

- reproducibly model therapeutic Nitric Oxide

Cell Research - nitric oxide chamber with dynamic control of parts per million NO, O2, and CO2 - GT4181N & C-Chamber

Animal Modeling - nitric oxide chamber(s) with dynamic control of parts per million NO - AT42N & A-Chamber(s)

Animal Modeling - nitric oxide chamber(s) with dynamic control of parts per million NO and limit control of NO2 by-product - AT82NN & A-Chamber(s)


- simulate musculoskeletal tissue O2 levels

- model pathologic hypoxia conditions

- increase MSC expansion

- generate appropriate cellular phenotype

- enhance chondrogenic differentiation

- enhance osteogenic differentiation

- enhance myogenic differentiation

- enhance tenogenic differentiation

Cell Research - physiologic oxygen chamber, hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - physiologic oxygen chamber, hypoxia chamber with dynamic control of O2 and CO2 - C42 & C-Chamber(s)

Cell Research - physiologic oxygen incubator and hood system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell handling chamber(s) - Xvivo System


- simulate physiological O2 levels

- reproducibly model hypoxic challenge

Cell Research - physiologic oxygen chamber, hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Animal Modeling - hypoxia chamber with static control of O2 - P360 & A-Chamber


- simulate physiologic pulmonary O2 levels

- reproducibly model pulmonary hypertension/PAH

- reproducibly model asthma

- reproducibly model COPD

- reproducibly model pulmonary fibrosis

Cell Research - physiologic oxygen chamber, hypoxia chamber, hyperoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Animal Modeling - hypoxia chamber, hyperoxia chamber with static control of O2 - P360 & A-Chamber

Animal Modeling - hypoxia chamber(s), hyperoxia chamber(s) with dynamic control of O2 - A84 & A-Chamber(s)


- remove ROS/oxidative stress artifact

- induce oxidative stress/ROS production

Cell Research - physiologic oxygen chamber, hypoxia chamber, hyperoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - physiologic oxygen incubator and hood system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell handling chamber(s) - Xvivo System


- reproducibly model therapeutic IH

- induce neural/respiratory plasticity response

Cell Research - intermittent hypoxia chamber(s) with dynamic control of O2 and CO2 - C42 & C-Chamber(s)

Animal Modeling - intermittent hypoxia chamber(s) with dynamic control of O2 - A84 & A-Chamber(s)

Animal Modeling - accessory kit for rapid profiling upgrade to intermittent hypoxia chamber(s) - Quick & Quiet Profiler


- reproducibly model sleep apnea IH

Cell Research - intermittent hypoxia chamber(s) with dynamic control of O2 and CO2 - C42 & C-Chamber(s)

Animal Modeling - intermittent hypoxia chamber(s) with dynamic control of O2 - A84 & A-Chamber(s)

Animal Modeling - accessory kit for rapid profiling upgrade to intermittent hypoxia chamber(s) - Quick & Quiet Profiler

Animal Modeling - intermittent hypoxia chamber(s) with dynamic control of O2 and CO2 - A42OC & A-Chamber(s)


- simulate physiological cellular O2 levels

- reproducibly model pathological hypoxia

- increase stem cell yield

- decrease cell doubling time

- improve cell phenotype characteristics

- maintain cell stemness characteristics

- increase cell reprogramming efficiency

- maintain stem cell quiescence

- control stem cell differentiation/lineage commitment

- improve cell engraftment/function

Cell Research - physiologic oxygen chamber, hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - physiologic oxygen chamber(s), hypoxia chamber(s) with dynamic control of O2 and CO2 - C42 & C-Chamber(s)

Cell Research - physiologic oxygen incubator and hood system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell handling chamber(s) - Xvivo System


- optimize conditions for organ/tissue engineering

- simulate physiologic tissue O2 conditions

- model ischemic transplant site conditions

Cell Research - physiologic oxygen chamber, hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - physiologic oxygen chamber(s), hypoxia chamber(s) with dynamic control of O2 and CO2 - C42 & C-Chamber(s)

Cell Research - physiologic oxygen incubator and hood system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell handling chamber(s) - Xvivo System


- simulate physiologic vascular tissue O2 levels

- improve cell-cell junction adhesion

- induce VEGF expression and angiogenesis

- promote neovascularization

- reproducibly model vascular oxidative stress/ROS production

- reproducibly model pathologic hypoxia/ischemia

Cell Research - physiologic oxygen chamber, hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - physiologic oxygen chamber(s), hypoxia chamber(s) with dynamic control of O2 and CO2 - C42 & C-Chamber(s)

Cell Research - physiologic oxygen incubator and hood system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell handling chamber(s) - Xvivo System


- simulate physiologic O2 levels in ocular tissue

- maintain multipotent properties of retinal progenitors

- control differentiation to desired ocular lineage

- remove ROS/oxidative stress artifact

- induce oxidative stress/ROS production

- induce ocular angiogenesis

- reproducibly model ROP and OIR

Cell Research - physiologic oxygen chamber, hypoxia chamber, hyperoxia chamber with static control of O2 and CO2 - C21 & C-Chamber

Cell Research - physiologic oxygen incubator and hood system, hypoxia workstation, hypoxia glove box with independently programmable control of O2, CO2, and Temperature in one (or more) modular incubator chamber(s) and/or cell handling chamber(s) - Xvivo System

Animal Modeling - hyperoxia chamber, hypoxia chamber with static control of O2 - P360 & A-Chamber

Animal Modeling - hyperoxia chamber(s), hypoxia chamber(s) with dynamic control of O2 - A84 & A-Chamber(s)